Result of FASTA (omim) for
pFN21AB4374
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4374, 414 aa
1>>>pF1KB4374 414 - 414 aa - 414 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3664+/-0.00035; mu= 11.5665+/- 0.022
mean_var=83.2377+/-17.425, 0's: 0 Z-trim(116.3): 221 B-trim: 2132 in 2/51
Lambda= 0.140577
statistics sampled from 27040 (27318) to 27040 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.689), E-opt: 0.2 (0.32), width: 16
Scan time: 8.420
The best scores are: opt bits E(85289)
NP_064525 (OMIM: 607815) ankyrin repeat and steril ( 414) 2812 580.0 3.6e-165
NP_001190999 (OMIM: 607815) ankyrin repeat and ste ( 426) 2657 548.6 1.1e-155
XP_016875154 (OMIM: 607815) PREDICTED: ankyrin rep ( 425) 2652 547.6 2.2e-155
XP_006719577 (OMIM: 607815) PREDICTED: ankyrin rep (1184) 2579 532.9 1.5e-150
XP_016875147 (OMIM: 607815) PREDICTED: ankyrin rep (1188) 2566 530.3 9.7e-150
NP_001190996 (OMIM: 607815) ankyrin repeat and ste ( 394) 2412 498.9 9.1e-141
XP_006719575 (OMIM: 607815) PREDICTED: ankyrin rep (1200) 2411 498.9 2.8e-140
XP_006719576 (OMIM: 607815) PREDICTED: ankyrin rep (1199) 2406 497.9 5.7e-140
NP_001191010 (OMIM: 607815) ankyrin repeat and ste ( 254) 1520 317.9 1.8e-86
NP_690001 (OMIM: 607815) ankyrin repeat and steril (1248) 1521 318.4 6.4e-86
XP_016875143 (OMIM: 607815) PREDICTED: ankyrin rep (1268) 1507 315.5 4.6e-85
XP_016875142 (OMIM: 607815) PREDICTED: ankyrin rep (1272) 1507 315.5 4.6e-85
XP_006719570 (OMIM: 607815) PREDICTED: ankyrin rep (1273) 1507 315.5 4.6e-85
XP_005269089 (OMIM: 607815) PREDICTED: ankyrin rep ( 266) 1365 286.5 5.3e-77
NP_001191009 (OMIM: 607815) ankyrin repeat and ste ( 266) 1365 286.5 5.3e-77
XP_016875153 (OMIM: 607815) PREDICTED: ankyrin rep ( 429) 1366 286.8 7.1e-77
XP_016875149 (OMIM: 607815) PREDICTED: ankyrin rep ( 486) 1366 286.8 7.9e-77
NP_001190997 (OMIM: 607815) ankyrin repeat and ste ( 460) 1361 285.8 1.5e-76
XP_005269086 (OMIM: 607815) PREDICTED: ankyrin rep (1256) 1366 286.9 1.9e-76
XP_005269085 (OMIM: 607815) PREDICTED: ankyrin rep (1260) 1366 286.9 1.9e-76
XP_016875146 (OMIM: 607815) PREDICTED: ankyrin rep (1226) 1365 286.7 2.1e-76
XP_006719573 (OMIM: 607815) PREDICTED: ankyrin rep (1235) 1364 286.5 2.4e-76
NP_001190994 (OMIM: 607815) ankyrin repeat and ste ( 290) 1352 283.9 3.6e-76
XP_006719572 (OMIM: 607815) PREDICTED: ankyrin rep (1259) 1361 285.9 3.8e-76
NP_001190998 (OMIM: 607815) ankyrin repeat and ste ( 450) 1352 283.9 5.3e-76
XP_016875152 (OMIM: 607815) PREDICTED: ankyrin rep ( 476) 1352 284.0 5.6e-76
XP_016875150 (OMIM: 607815) PREDICTED: ankyrin rep ( 479) 1352 284.0 5.6e-76
NP_858056 (OMIM: 607815) ankyrin repeat and steril ( 510) 1352 284.0 5.9e-76
XP_016875148 (OMIM: 607815) PREDICTED: ankyrin rep ( 511) 1352 284.0 5.9e-76
NP_001191008 (OMIM: 607815) ankyrin repeat and ste ( 290) 1347 282.9 7.2e-76
NP_001190995 (OMIM: 607815) ankyrin repeat and ste ( 357) 1347 282.9 8.7e-76
XP_016875151 (OMIM: 607815) PREDICTED: ankyrin rep ( 479) 1347 282.9 1.1e-75
XP_016875145 (OMIM: 607815) PREDICTED: ankyrin rep (1250) 1352 284.1 1.3e-75
XP_011536873 (OMIM: 607815) PREDICTED: ankyrin rep (1251) 1352 284.1 1.3e-75
XP_016875141 (OMIM: 607815) PREDICTED: ankyrin rep (1281) 1352 284.1 1.4e-75
XP_006719567 (OMIM: 607815) PREDICTED: ankyrin rep (1284) 1352 284.1 1.4e-75
XP_016875140 (OMIM: 607815) PREDICTED: ankyrin rep (1285) 1352 284.1 1.4e-75
XP_016875144 (OMIM: 607815) PREDICTED: ankyrin rep (1259) 1350 283.7 1.8e-75
XP_006719571 (OMIM: 607815) PREDICTED: ankyrin rep (1260) 1350 283.7 1.8e-75
XP_006719569 (OMIM: 607815) PREDICTED: ankyrin rep (1283) 1347 283.1 2.7e-75
XP_006719568 (OMIM: 607815) PREDICTED: ankyrin rep (1284) 1347 283.1 2.7e-75
XP_016866082 (OMIM: 608994) PREDICTED: ankyrin rep ( 593) 655 142.6 2.4e-33
XP_011512739 (OMIM: 608994) PREDICTED: ankyrin rep ( 604) 655 142.6 2.5e-33
XP_011512738 (OMIM: 608994) PREDICTED: ankyrin rep (1100) 655 142.7 4.2e-33
NP_056060 (OMIM: 608994) ankyrin repeat and SAM do (1134) 655 142.7 4.3e-33
XP_011512737 (OMIM: 608994) PREDICTED: ankyrin rep (1144) 655 142.7 4.4e-33
XP_011512736 (OMIM: 608994) PREDICTED: ankyrin rep (1145) 655 142.7 4.4e-33
XP_005249021 (OMIM: 608994) PREDICTED: ankyrin rep (1155) 655 142.7 4.4e-33
XP_006715099 (OMIM: 608994) PREDICTED: ankyrin rep (1156) 655 142.7 4.4e-33
XP_011512735 (OMIM: 608994) PREDICTED: ankyrin rep (1162) 655 142.7 4.4e-33
>>NP_064525 (OMIM: 607815) ankyrin repeat and sterile al (414 aa)
initn: 2812 init1: 2812 opt: 2812 Z-score: 3086.3 bits: 580.0 E(85289): 3.6e-165
Smith-Waterman score: 2812; 100.0% identity (100.0% similar) in 414 aa overlap (1-414:1-414)
10 20 30 40 50 60
pF1KB4 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 PPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 PPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK
310 320 330 340 350 360
370 380 390 400 410
pF1KB4 GGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 GGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
370 380 390 400 410
>>NP_001190999 (OMIM: 607815) ankyrin repeat and sterile (426 aa)
initn: 2736 init1: 2654 opt: 2657 Z-score: 2916.2 bits: 548.6 E(85289): 1.1e-155
Smith-Waterman score: 2657; 96.8% identity (98.0% similar) in 407 aa overlap (1-407:1-399)
10 20 30 40 50 60
pF1KB4 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 PPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK
310 320 330 340 350 360
370 380 390 400 410
pF1KB4 GGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
::::::::::::::::::::::::::::::.. .:::..:
NP_001 GGHSSTLPESFENKPSKPIPKPRVSIRKSVQI--------DPSEQKTLANLPWIVEPGQE
370 380 390 400 410
NP_001 AKRGINTKYETTIF
420
>>XP_016875154 (OMIM: 607815) PREDICTED: ankyrin repeat (425 aa)
initn: 2652 init1: 2652 opt: 2652 Z-score: 2910.8 bits: 547.6 E(85289): 2.2e-155
Smith-Waterman score: 2652; 100.0% identity (100.0% similar) in 390 aa overlap (1-390:1-390)
10 20 30 40 50 60
pF1KB4 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 PPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK
310 320 330 340 350 360
370 380 390 400 410
pF1KB4 GGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
::::::::::::::::::::::::::::::
XP_016 GGHSSTLPESFENKPSKPIPKPRVSIRKSVIDPSEQKTLANLPWIVEPGQEAKRGINTKY
370 380 390 400 410 420
>>XP_006719577 (OMIM: 607815) PREDICTED: ankyrin repeat (1184 aa)
initn: 2579 init1: 2579 opt: 2579 Z-score: 2823.6 bits: 532.9 E(85289): 1.5e-150
Smith-Waterman score: 2579; 99.0% identity (99.7% similar) in 387 aa overlap (28-414:798-1184)
10 20 30 40 50
pF1KB4 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHL
:. ..:::::::::::::::::::::::::
XP_006 GNSERTPSFTSEWEEIDKIMSSIDVGINNELKEMNGPRCPVQTVGQWLESIGLPQYENHL
770 780 790 800 810 820
60 70 80 90 100 110
pF1KB4 MANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAE
830 840 850 860 870 880
120 130 140 150 160 170
pF1KB4 WLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDP
890 900 910 920 930 940
180 190 200 210 220 230
pF1KB4 PQKPPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQKPPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSML
950 960 970 980 990 1000
240 250 260 270 280 290
pF1KB4 IKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIR
1010 1020 1030 1040 1050 1060
300 310 320 330 340 350
pF1KB4 NISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQ
1070 1080 1090 1100 1110 1120
360 370 380 390 400 410
pF1KB4 ARKGGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ARKGGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
1130 1140 1150 1160 1170 1180
>>XP_016875147 (OMIM: 607815) PREDICTED: ankyrin repeat (1188 aa)
initn: 2566 init1: 2566 opt: 2566 Z-score: 2809.3 bits: 530.3 E(85289): 9.7e-150
Smith-Waterman score: 2566; 99.7% identity (99.7% similar) in 383 aa overlap (32-414:806-1188)
10 20 30 40 50 60
pF1KB4 MWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMANG
: ::::::::::::::::::::::::::::
XP_016 FTSEWEEIDKIMSSIDVGINNELKEMNGETTRPRCPVQTVGQWLESIGLPQYENHLMANG
780 790 800 810 820 830
70 80 90 100 110 120
pF1KB4 FDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDS
840 850 860 870 880 890
130 140 150 160 170 180
pF1KB4 IELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKP
900 910 920 930 940 950
190 200 210 220 230 240
pF1KB4 PRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKEL
960 970 980 990 1000 1010
250 260 270 280 290 300
pF1KB4 RGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC
1020 1030 1040 1050 1060 1070
310 320 330 340 350 360
pF1KB4 AAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKG
1080 1090 1100 1110 1120 1130
370 380 390 400 410
pF1KB4 GHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
1140 1150 1160 1170 1180
>>NP_001190996 (OMIM: 607815) ankyrin repeat and sterile (394 aa)
initn: 2412 init1: 2412 opt: 2412 Z-score: 2648.2 bits: 498.9 E(85289): 9.1e-141
Smith-Waterman score: 2412; 100.0% identity (100.0% similar) in 358 aa overlap (33-390:2-359)
10 20 30 40 50 60
pF1KB4 WQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMANGF
::::::::::::::::::::::::::::::
NP_001 MGPRCPVQTVGQWLESIGLPQYENHLMANGF
10 20 30
70 80 90 100 110 120
pF1KB4 DNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSI
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB4 ELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKPP
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB4 RSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELR
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB4 GTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCA
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB4 AQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGG
280 290 300 310 320 330
370 380 390 400 410
pF1KB4 HSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
::::::::::::::::::::::::::::
NP_001 HSSTLPESFENKPSKPIPKPRVSIRKSVIDPSEQKTLANLPWIVEPGQEAKRGINTKYET
340 350 360 370 380 390
>>XP_006719575 (OMIM: 607815) PREDICTED: ankyrin repeat (1200 aa)
initn: 2488 init1: 2406 opt: 2411 Z-score: 2639.4 bits: 498.9 E(85289): 2.8e-140
Smith-Waterman score: 2411; 96.3% identity (97.6% similar) in 376 aa overlap (32-407:806-1173)
10 20 30 40 50 60
pF1KB4 MWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMANG
: ::::::::::::::::::::::::::::
XP_006 FTSEWEEIDKIMSSIDVGINNELKEMNGETTRPRCPVQTVGQWLESIGLPQYENHLMANG
780 790 800 810 820 830
70 80 90 100 110 120
pF1KB4 FDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDS
840 850 860 870 880 890
130 140 150 160 170 180
pF1KB4 IELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKP
900 910 920 930 940 950
190 200 210 220 230 240
pF1KB4 PRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKEL
960 970 980 990 1000 1010
250 260 270 280 290 300
pF1KB4 RGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC
1020 1030 1040 1050 1060 1070
310 320 330 340 350 360
pF1KB4 AAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKG
1080 1090 1100 1110 1120 1130
370 380 390 400 410
pF1KB4 GHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
:::::::::::::::::::::::::::::.. .:::..:
XP_006 GHSSTLPESFENKPSKPIPKPRVSIRKSVQI--------DPSEQKTLANLPWIVEPGQEA
1140 1150 1160 1170 1180
XP_006 KRGINTKYETTIF
1190 1200
>>XP_006719576 (OMIM: 607815) PREDICTED: ankyrin repeat (1199 aa)
initn: 2406 init1: 2406 opt: 2406 Z-score: 2633.9 bits: 497.9 E(85289): 5.7e-140
Smith-Waterman score: 2406; 99.7% identity (99.7% similar) in 359 aa overlap (32-390:806-1164)
10 20 30 40 50 60
pF1KB4 MWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMANG
: ::::::::::::::::::::::::::::
XP_006 FTSEWEEIDKIMSSIDVGINNELKEMNGETTRPRCPVQTVGQWLESIGLPQYENHLMANG
780 790 800 810 820 830
70 80 90 100 110 120
pF1KB4 FDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDS
840 850 860 870 880 890
130 140 150 160 170 180
pF1KB4 IELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKP
900 910 920 930 940 950
190 200 210 220 230 240
pF1KB4 PRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKEL
960 970 980 990 1000 1010
250 260 270 280 290 300
pF1KB4 RGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC
1020 1030 1040 1050 1060 1070
310 320 330 340 350 360
pF1KB4 AAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKG
1080 1090 1100 1110 1120 1130
370 380 390 400 410
pF1KB4 GHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
:::::::::::::::::::::::::::::
XP_006 GHSSTLPESFENKPSKPIPKPRVSIRKSVIDPSEQKTLANLPWIVEPGQEAKRGINTKYE
1140 1150 1160 1170 1180 1190
>>NP_001191010 (OMIM: 607815) ankyrin repeat and sterile (254 aa)
initn: 1520 init1: 1520 opt: 1520 Z-score: 1673.6 bits: 317.9 E(85289): 1.8e-86
Smith-Waterman score: 1520; 95.4% identity (97.1% similar) in 240 aa overlap (175-414:15-254)
150 160 170 180 190 200
pF1KB4 IWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKPPRSITLRTGDWGEPSITLRPPNE
:: :.. . .::::::::::::::::
NP_001 MQGDARRRRNENYFDDIPRSKLERQMAQTGDWGEPSITLRPPNE
10 20 30 40
210 220 230 240 250 260
pF1KB4 ATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQ
50 60 70 80 90 100
270 280 290 300 310 320
pF1KB4 MKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHH
110 120 130 140 150 160
330 340 350 360 370 380
pF1KB4 YCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLPESFENKPSKPIPKPRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLPESFENKPSKPIPKPRV
170 180 190 200 210 220
390 400 410
pF1KB4 SIRKSVDLLHASHTGQEPSERHTEEALRKF
::::::::::::::::::::::::::::::
NP_001 SIRKSVDLLHASHTGQEPSERHTEEALRKF
230 240 250
>>NP_690001 (OMIM: 607815) ankyrin repeat and sterile al (1248 aa)
initn: 1602 init1: 1520 opt: 1521 Z-score: 1663.6 bits: 318.4 E(85289): 6.4e-86
Smith-Waterman score: 2436; 86.2% identity (86.2% similar) in 443 aa overlap (32-414:806-1248)
10 20 30 40 50 60
pF1KB4 MWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMANG
: ::::::::::::::::::::::::::::
NP_690 FTSEWEEIDKIMSSIDVGINNELKEMNGETTRPRCPVQTVGQWLESIGLPQYENHLMANG
780 790 800 810 820 830
70 80 90 100 110 120
pF1KB4 FDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 FDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDS
840 850 860 870 880 890
130 140 150 160 170 180
pF1KB4 IELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 IELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKP
900 910 920 930 940 950
pF1KB4 PRSITLR-----------------------------------------------------
:::::::
NP_690 PRSITLREPSGNHTPPQLSPSLSQSTYTTGGSLDVPHIIMQGDARRRRNENYFDDIPRSK
960 970 980 990 1000 1010
190 200 210 220 230 240
pF1KB4 -------TGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKEL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 LERQMAQTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKEL
1020 1030 1040 1050 1060 1070
250 260 270 280 290 300
pF1KB4 RGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 RGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC
1080 1090 1100 1110 1120 1130
310 320 330 340 350 360
pF1KB4 AAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 AAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKG
1140 1150 1160 1170 1180 1190
370 380 390 400 410
pF1KB4 GHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 GHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
1200 1210 1220 1230 1240
414 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:49:03 2016 done: Sat Nov 5 05:49:05 2016
Total Scan time: 8.420 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]