Result of FASTA (omim) for
pFN21AB3799
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3799, 485 aa
1>>>pF1KB3799 485 - 485 aa - 485 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8193+/-0.000404; mu= 16.3287+/- 0.025
mean_var=118.9052+/-25.424, 0's: 0 Z-trim(113.9): 199 B-trim: 1347 in 1/56
Lambda= 0.117618
statistics sampled from 23190 (23435) to 23190 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.64), E-opt: 0.2 (0.275), width: 16
Scan time: 9.160
The best scores are: opt bits E(85289)
XP_006724602 (OMIM: 300512) PREDICTED: WD repeat-c ( 485) 3242 561.8 1.5e-159
XP_011542249 (OMIM: 300512) PREDICTED: WD repeat-c ( 485) 3242 561.8 1.5e-159
NP_060353 (OMIM: 300512) WD repeat-containing prot ( 485) 3242 561.8 1.5e-159
XP_006724604 (OMIM: 300512) PREDICTED: WD repeat-c ( 393) 2633 458.4 1.7e-128
NP_001159898 (OMIM: 300512) WD repeat-containing p ( 393) 2633 458.4 1.7e-128
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 270 57.3 7.7e-08
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 270 57.3 7.7e-08
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 270 57.3 7.7e-08
NP_056975 (OMIM: 605585) pre-mRNA-processing facto ( 579) 210 47.4 0.00013
NP_001128304 (OMIM: 608629,608894) jouberin isofor (1053) 201 46.1 0.00057
XP_016866473 (OMIM: 608629,608894) PREDICTED: joub (1053) 201 46.1 0.00057
XP_016866472 (OMIM: 608629,608894) PREDICTED: joub (1064) 201 46.1 0.00057
XP_016866471 (OMIM: 608629,608894) PREDICTED: joub (1168) 201 46.2 0.00061
XP_016866470 (OMIM: 608629,608894) PREDICTED: joub (1178) 201 46.2 0.00061
XP_016866469 (OMIM: 608629,608894) PREDICTED: joub (1179) 201 46.2 0.00061
XP_016866467 (OMIM: 608629,608894) PREDICTED: joub (1186) 201 46.2 0.00062
XP_016866468 (OMIM: 608629,608894) PREDICTED: joub (1186) 201 46.2 0.00062
NP_001128302 (OMIM: 608629,608894) jouberin isofor (1196) 201 46.2 0.00062
XP_011534213 (OMIM: 608629,608894) PREDICTED: joub (1196) 201 46.2 0.00062
XP_011534212 (OMIM: 608629,608894) PREDICTED: joub (1196) 201 46.2 0.00062
XP_016866466 (OMIM: 608629,608894) PREDICTED: joub (1196) 201 46.2 0.00062
NP_001128303 (OMIM: 608629,608894) jouberin isofor (1196) 201 46.2 0.00062
NP_060121 (OMIM: 608629,608894) jouberin isoform a (1196) 201 46.2 0.00062
XP_016878126 (OMIM: 609540) PREDICTED: WD repeat-c ( 270) 185 42.8 0.0015
XP_011520396 (OMIM: 609540) PREDICTED: WD repeat-c ( 305) 185 42.8 0.0016
NP_001290176 (OMIM: 609540) WD repeat-containing p ( 305) 185 42.8 0.0016
NP_079510 (OMIM: 609540) WD repeat-containing prot ( 305) 185 42.8 0.0016
XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD re ( 540) 188 43.6 0.0017
NP_001013433 (OMIM: 606278) F-box/WD repeat-contai ( 589) 188 43.7 0.0018
NP_060785 (OMIM: 606278) F-box/WD repeat-containin ( 627) 188 43.7 0.0018
XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 188 43.7 0.0019
XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 188 43.7 0.0019
XP_011530386 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 188 43.7 0.002
XP_011530385 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 188 43.7 0.002
NP_361014 (OMIM: 606278) F-box/WD repeat-containin ( 707) 188 43.7 0.002
XP_011530387 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 188 43.7 0.002
XP_016863851 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 188 43.7 0.002
>>XP_006724602 (OMIM: 300512) PREDICTED: WD repeat-conta (485 aa)
initn: 3242 init1: 3242 opt: 3242 Z-score: 2985.2 bits: 561.8 E(85289): 1.5e-159
Smith-Waterman score: 3242; 100.0% identity (100.0% similar) in 485 aa overlap (1-485:1-485)
10 20 30 40 50 60
pF1KB3 MAAVWQQVLAVDARYNAYRTPTFPQFRTQYIRRRSQLLRENAKAGHPPALRRQYLRLRGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAAVWQQVLAVDARYNAYRTPTFPQFRTQYIRRRSQLLRENAKAGHPPALRRQYLRLRGQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LLGQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLGQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 AQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 ANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDAT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 MRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 SKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISAR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 SWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 GACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVW
430 440 450 460 470 480
pF1KB3 RREQK
:::::
XP_006 RREQK
>>XP_011542249 (OMIM: 300512) PREDICTED: WD repeat-conta (485 aa)
initn: 3242 init1: 3242 opt: 3242 Z-score: 2985.2 bits: 561.8 E(85289): 1.5e-159
Smith-Waterman score: 3242; 100.0% identity (100.0% similar) in 485 aa overlap (1-485:1-485)
10 20 30 40 50 60
pF1KB3 MAAVWQQVLAVDARYNAYRTPTFPQFRTQYIRRRSQLLRENAKAGHPPALRRQYLRLRGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAVWQQVLAVDARYNAYRTPTFPQFRTQYIRRRSQLLRENAKAGHPPALRRQYLRLRGQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LLGQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLGQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 AQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 ANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDAT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 MRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 SKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISAR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 SWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 GACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVW
430 440 450 460 470 480
pF1KB3 RREQK
:::::
XP_011 RREQK
>>NP_060353 (OMIM: 300512) WD repeat-containing protein (485 aa)
initn: 3242 init1: 3242 opt: 3242 Z-score: 2985.2 bits: 561.8 E(85289): 1.5e-159
Smith-Waterman score: 3242; 100.0% identity (100.0% similar) in 485 aa overlap (1-485:1-485)
10 20 30 40 50 60
pF1KB3 MAAVWQQVLAVDARYNAYRTPTFPQFRTQYIRRRSQLLRENAKAGHPPALRRQYLRLRGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MAAVWQQVLAVDARYNAYRTPTFPQFRTQYIRRRSQLLRENAKAGHPPALRRQYLRLRGQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LLGQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LLGQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 AQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 AQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 ANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDAT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 MRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 SKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISAR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 SWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 GACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVW
430 440 450 460 470 480
pF1KB3 RREQK
:::::
NP_060 RREQK
>>XP_006724604 (OMIM: 300512) PREDICTED: WD repeat-conta (393 aa)
initn: 2633 init1: 2633 opt: 2633 Z-score: 2427.8 bits: 458.4 E(85289): 1.7e-128
Smith-Waterman score: 2633; 100.0% identity (100.0% similar) in 393 aa overlap (93-485:1-393)
70 80 90 100 110 120
pF1KB3 GQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQAQ
::::::::::::::::::::::::::::::
XP_006 MEDFEDDPRALGARGHRRSVSRGSYQLQAQ
10 20 30
130 140 150 160 170 180
pF1KB3 MNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRFAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRFAN
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB3 DDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDATMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDATMR
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB3 IWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGSSK
160 170 180 190 200 210
310 320 330 340 350 360
pF1KB3 LTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISARSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISARSW
220 230 240 250 260 270
370 380 390 400 410 420
pF1KB3 VSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQGA
280 290 300 310 320 330
430 440 450 460 470 480
pF1KB3 CVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVWRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVWRR
340 350 360 370 380 390
pF1KB3 EQK
:::
XP_006 EQK
>>NP_001159898 (OMIM: 300512) WD repeat-containing prote (393 aa)
initn: 2633 init1: 2633 opt: 2633 Z-score: 2427.8 bits: 458.4 E(85289): 1.7e-128
Smith-Waterman score: 2633; 100.0% identity (100.0% similar) in 393 aa overlap (93-485:1-393)
70 80 90 100 110 120
pF1KB3 GQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQAQ
::::::::::::::::::::::::::::::
NP_001 MEDFEDDPRALGARGHRRSVSRGSYQLQAQ
10 20 30
130 140 150 160 170 180
pF1KB3 MNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRFAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRFAN
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB3 DDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDATMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDATMR
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB3 IWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGSSK
160 170 180 190 200 210
310 320 330 340 350 360
pF1KB3 LTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISARSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISARSW
220 230 240 250 260 270
370 380 390 400 410 420
pF1KB3 VSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQGA
280 290 300 310 320 330
430 440 450 460 470 480
pF1KB3 CVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVWRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVWRR
340 350 360 370 380 390
pF1KB3 EQK
:::
NP_001 EQK
>>XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-conta (334 aa)
initn: 337 init1: 123 opt: 270 Z-score: 261.7 bits: 57.3 E(85289): 7.7e-08
Smith-Waterman score: 342; 26.0% identity (57.7% similar) in 350 aa overlap (138-483:19-333)
110 120 130 140 150 160
pF1KB3 HRRSVSRGSYQLQAQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVF
:.:.: :. : .. ::: . ..
XP_005 MATEEKKPETEAARAQPTPSSSATQSKP----TPVKPNYA---LKFTL
10 20 30 40
170 180 190 200 210 220
pF1KB3 DQHVDEAVPRVRFANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSL
:. .:: :.:. . . :: : : :.. . ... :: :.:: :::
XP_005 AGHT-KAVSSVKFSPNGEW-LASSSADKLIKIWGAYDGK--FEKTISGHKLGISDVAWSS
50 60 70 80 90
230 240 250 260 270 280
pF1KB3 SNDILVSTSLDATMRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHV
....:::.: : :..:: .:.:.. . : ..::.:.: ..:: : :. ..:..
XP_005 DSNLLVSASDDKTLKIWDVSSGKCLKTLKG-HSNYVFCCNFNP-QSNLIVSGSFDESVRI
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB3 MNISTGKKVKGGSSKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLV
...::: .: .. . : :. :. : :. ... : . ..: :.:. :. :.
XP_005 WDVKTGKCLKTLPAH-SDPVSAVHFNRDGSLIVSSSYDG--LCRIWDTASGQCLKT--LI
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB3 VHEGSPVTSISARSWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHP
.. ::. . . . . . .. : :.. : .. : :: ..:
XP_005 DDDNPPVSFV-------KFSPNGKYILAATLDNTL--KLWDYSKGKCLK-----TYTGHK
220 230 240 250
410 420 430 440 450 460
pF1KB3 VRSIFCPLMSFR--QGACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDE
.. .: . .: : .:.:::: :...... .: :.:::::. :.... . :
XP_005 NEK-YCIFANFSVTGGKWIVSGSEDNLVYIWNLQ--TKEIVQKLQGHTDVVISTACHPTE
260 270 280 290 300 310
470 480
pF1KB3 SLLASS--DASGMVIVWRREQK
...::. . . . .:. .
XP_005 NIIASAALENDKTIKLWKSDC
320 330
>>NP_438172 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 337 init1: 123 opt: 270 Z-score: 261.7 bits: 57.3 E(85289): 7.7e-08
Smith-Waterman score: 342; 26.0% identity (57.7% similar) in 350 aa overlap (138-483:19-333)
110 120 130 140 150 160
pF1KB3 HRRSVSRGSYQLQAQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVF
:.:.: :. : .. ::: . ..
NP_438 MATEEKKPETEAARAQPTPSSSATQSKP----TPVKPNYA---LKFTL
10 20 30 40
170 180 190 200 210 220
pF1KB3 DQHVDEAVPRVRFANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSL
:. .:: :.:. . . :: : : :.. . ... :: :.:: :::
NP_438 AGHT-KAVSSVKFSPNGEW-LASSSADKLIKIWGAYDGK--FEKTISGHKLGISDVAWSS
50 60 70 80 90
230 240 250 260 270 280
pF1KB3 SNDILVSTSLDATMRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHV
....:::.: : :..:: .:.:.. . : ..::.:.: ..:: : :. ..:..
NP_438 DSNLLVSASDDKTLKIWDVSSGKCLKTLKG-HSNYVFCCNFNP-QSNLIVSGSFDESVRI
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB3 MNISTGKKVKGGSSKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLV
...::: .: .. . : :. :. : :. ... : . ..: :.:. :. :.
NP_438 WDVKTGKCLKTLPAH-SDPVSAVHFNRDGSLIVSSSYDG--LCRIWDTASGQCLKT--LI
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB3 VHEGSPVTSISARSWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHP
.. ::. . . . . . .. : :.. : .. : :: ..:
NP_438 DDDNPPVSFV-------KFSPNGKYILAATLDNTL--KLWDYSKGKCLK-----TYTGHK
220 230 240 250
410 420 430 440 450 460
pF1KB3 VRSIFCPLMSFR--QGACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDE
.. .: . .: : .:.:::: :...... .: :.:::::. :.... . :
NP_438 NEK-YCIFANFSVTGGKWIVSGSEDNLVYIWNLQ--TKEIVQKLQGHTDVVISTACHPTE
260 270 280 290 300 310
470 480
pF1KB3 SLLASS--DASGMVIVWRREQK
...::. . . . .:. .
NP_438 NIIASAALENDKTIKLWKSDC
320 330
>>NP_060058 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 337 init1: 123 opt: 270 Z-score: 261.7 bits: 57.3 E(85289): 7.7e-08
Smith-Waterman score: 342; 26.0% identity (57.7% similar) in 350 aa overlap (138-483:19-333)
110 120 130 140 150 160
pF1KB3 HRRSVSRGSYQLQAQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVF
:.:.: :. : .. ::: . ..
NP_060 MATEEKKPETEAARAQPTPSSSATQSKP----TPVKPNYA---LKFTL
10 20 30 40
170 180 190 200 210 220
pF1KB3 DQHVDEAVPRVRFANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSL
:. .:: :.:. . . :: : : :.. . ... :: :.:: :::
NP_060 AGHT-KAVSSVKFSPNGEW-LASSSADKLIKIWGAYDGK--FEKTISGHKLGISDVAWSS
50 60 70 80 90
230 240 250 260 270 280
pF1KB3 SNDILVSTSLDATMRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHV
....:::.: : :..:: .:.:.. . : ..::.:.: ..:: : :. ..:..
NP_060 DSNLLVSASDDKTLKIWDVSSGKCLKTLKG-HSNYVFCCNFNP-QSNLIVSGSFDESVRI
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB3 MNISTGKKVKGGSSKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLV
...::: .: .. . : :. :. : :. ... : . ..: :.:. :. :.
NP_060 WDVKTGKCLKTLPAH-SDPVSAVHFNRDGSLIVSSSYDG--LCRIWDTASGQCLKT--LI
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB3 VHEGSPVTSISARSWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHP
.. ::. . . . . . .. : :.. : .. : :: ..:
NP_060 DDDNPPVSFV-------KFSPNGKYILAATLDNTL--KLWDYSKGKCLK-----TYTGHK
220 230 240 250
410 420 430 440 450 460
pF1KB3 VRSIFCPLMSFR--QGACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDE
.. .: . .: : .:.:::: :...... .: :.:::::. :.... . :
NP_060 NEK-YCIFANFSVTGGKWIVSGSEDNLVYIWNLQ--TKEIVQKLQGHTDVVISTACHPTE
260 270 280 290 300 310
470 480
pF1KB3 SLLASS--DASGMVIVWRREQK
...::. . . . .:. .
NP_060 NIIASAALENDKTIKLWKSDC
320 330
>>NP_056975 (OMIM: 605585) pre-mRNA-processing factor 17 (579 aa)
initn: 107 init1: 107 opt: 210 Z-score: 203.7 bits: 47.4 E(85289): 0.00013
Smith-Waterman score: 214; 21.9% identity (55.3% similar) in 320 aa overlap (165-480:282-578)
140 150 160 170 180 190
pF1KB3 SVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRFANDDRHRLACCSLD
::.. :. ..: ::. . : : ::.:
NP_056 RSYLHIPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHT-KGVSAVRLFPLSGHLLLSCSMD
260 270 280 290 300 310
200 210 220 230 240 250
pF1KB3 GSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDATMRIWASEDGRCIRE
.:.: . : . ::.. ::...: :. .. .. ..:.. : ...: .: :.:: .
NP_056 CKIKLWE-VYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISR
320 330 340 350 360
260 270 280 290 300 310
pF1KB3 IPDPDSAELLCCTFQPVNN--NLTVVGNAKHNVHVMNISTGKKVKGGSSKLTGRVLALSF
. . : :.: .. :: :.: . ... .: .:. :. . .: : : .. :
NP_056 FTNRKVP--YCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHL-GAVNTIVF
370 380 390 400 410 420
320 330 340 350 360 370
pF1KB3 -DAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISARSWVSREARDPS
: :.. ..::. :. . .:. . . . .: :: .:.. .. : .
NP_056 VDENRRFVSTSDDK-SLRVWEWDIPVD-FKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQ
430 440 450 460 470 480
380 390 400 410 420 430
pF1KB3 LLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQGACVVTGSEDM
.:: . :.. : . .: . . .. : : ::. :..:. .
NP_056 ILIFGAQNRFRLNKKKIFKGHMVAGYACQVD---------FSPDMSY-----VISGDGNG
490 500 510 520 530
440 450 460 470 480
pF1KB3 CVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDE-SLLASSDASGMVIVWRREQK
....: ...: .....:. . . .. : : . . .:.. .:
NP_056 KLNIWDW-KTTKL-YSRFKAHDKVCIGAVWHPHETSKVITCGWDGLIKLWD
540 550 560 570
>>NP_001128304 (OMIM: 608629,608894) jouberin isoform b (1053 aa)
initn: 129 init1: 95 opt: 201 Z-score: 192.3 bits: 46.1 E(85289): 0.00057
Smith-Waterman score: 203; 21.5% identity (49.9% similar) in 381 aa overlap (114-469:548-903)
90 100 110 120 130 140
pF1KB3 RSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQAQMNRAVYEDR--PPGSVVPTSA
:. . :: . .. :. .: .:: .
NP_001 WSKCPRNHYPSTLYVTVRGLKVPDCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPG
520 530 540 550 560 570
150 160 170 180 190
pF1KB3 AEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRFANDDRH--RL---ACCSLDGS
: :. . : . :.:. .. : : : : : :. :: : ::
NP_001 LEESKEVIKWKRLPGQACRIPNKHLFSLNAGE---RGCFCLDFSHNGRILAAACASRDGY
580 590 600 610 620 630
200 210 220 230 240 250
pF1KB3 ISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDATMRIWASE--DGRCIRE
. .:. .: : :: . :..:: .. ....: :.: ::: .: . .:
NP_001 PIILYEIPSG-RFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRV
640 650 660 670 680 690
260 270 280 290 300
pF1KB3 IPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGSSKLTGR-------V
.: : . . :.:. .:.:.: ... .. ... :. :. . .
NP_001 LPHP--SFVYTAKFHPAVRELVVTGCYDSMIRIWKV----EMREDSAILVRQFDVHKSFI
700 710 720 730 740
310 320 330 340 350
pF1KB3 LALSFDAPGRLLWAGDDRGSVFSF-----LFDMATG----KLTKAKRLVVHEGSPVTSIS
.: ::. :. ...:: : . . . :. . ..: . . .: :.. .
NP_001 NSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEFKGIPISYLE
750 760 770 780 790 800
360 370 380 390 400 410
pF1KB3 ARSWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSF
. .: :::.. . : :..: . : .. . . ..: . : .:
NP_001 IHPNGKR------LLIHTKDSTL---RIMDLR-ILVARKFVGAANYREKIHSTLTPCGTF
810 820 830 840 850
420 430 440 450 460 470
pF1KB3 RQGACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVI
. .:::: :. .. : . ..:. . ..:. :.:.. :...:
NP_001 -----LFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFENMVAFCAFGQNEP
860 870 880 890 900 910
480
pF1KB3 VWRREQK
NP_001 ILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGSFQIDEFVHTESS
920 930 940 950 960 970
485 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:23:27 2016 done: Sat Nov 5 05:23:28 2016
Total Scan time: 9.160 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]