Result of FASTA (omim) for
pFN21AB3122
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3122, 218 aa
1>>>pF1KB3122 218 - 218 aa - 218 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5721+/-0.000266; mu= 8.8448+/- 0.017
mean_var=98.1584+/-20.287, 0's: 0 Z-trim(122.0): 39 B-trim: 2075 in 1/51
Lambda= 0.129452
statistics sampled from 39466 (39514) to 39466 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.797), E-opt: 0.2 (0.463), width: 16
Scan time: 6.230
The best scores are: opt bits E(85289)
NP_001166961 (OMIM: 300935) transmembrane gamma-ca ( 218) 1493 288.1 7.9e-78
NP_001166960 (OMIM: 300935) transmembrane gamma-ca ( 218) 1493 288.1 7.9e-78
NP_001135867 (OMIM: 300935) transmembrane gamma-ca ( 218) 1493 288.1 7.9e-78
NP_000941 (OMIM: 300935) transmembrane gamma-carbo ( 218) 1493 288.1 7.9e-78
NP_001166957 (OMIM: 300935) transmembrane gamma-ca ( 82) 381 80.2 1.1e-15
NP_076987 (OMIM: 300685) transmembrane gamma-carbo ( 231) 362 76.8 3.2e-14
XP_005274804 (OMIM: 300685) PREDICTED: transmembra ( 231) 362 76.8 3.2e-14
XP_011529499 (OMIM: 300685) PREDICTED: transmembra ( 231) 362 76.8 3.2e-14
NP_000122 (OMIM: 227500,608446,613878) coagulation ( 466) 287 63.0 9.5e-10
XP_006720026 (OMIM: 227500,608446,613878) PREDICTE ( 412) 281 61.8 1.9e-09
NP_062562 (OMIM: 227500,608446,613878) coagulation ( 444) 281 61.9 2e-09
XP_011535776 (OMIM: 227500,608446,613878) PREDICTE ( 495) 281 61.9 2.2e-09
NP_001299604 (OMIM: 227600,613872) coagulation fac ( 332) 267 59.2 9.5e-09
NP_001299603 (OMIM: 227600,613872) coagulation fac ( 444) 267 59.2 1.2e-08
XP_005262454 (OMIM: 122700,300746,300807,306900) P ( 418) 266 59.0 1.3e-08
NP_000495 (OMIM: 227600,613872) coagulation factor ( 488) 267 59.3 1.3e-08
NP_000124 (OMIM: 122700,300746,300807,306900) coag ( 461) 266 59.1 1.4e-08
NP_001300842 (OMIM: 122700,300746,300807,306900) c ( 423) 245 55.1 2e-07
XP_011525426 (OMIM: 604429) PREDICTED: transmembra ( 179) 235 53.1 3.5e-07
NP_001303264 (OMIM: 604429) transmembrane gamma-ca ( 179) 235 53.1 3.5e-07
NP_000942 (OMIM: 604429) transmembrane gamma-carbo ( 202) 235 53.1 3.9e-07
XP_006723349 (OMIM: 604429) PREDICTED: transmembra ( 202) 235 53.1 3.9e-07
NP_001298186 (OMIM: 176930,188050,601367,613679,61 ( 606) 242 54.6 4e-07
NP_000497 (OMIM: 176930,188050,601367,613679,61439 ( 622) 242 54.6 4.1e-07
XP_006718377 (OMIM: 611690) PREDICTED: transmembra ( 226) 221 50.5 2.6e-06
NP_076986 (OMIM: 611690) transmembrane gamma-carbo ( 226) 221 50.5 2.6e-06
NP_000303 (OMIM: 176860,612283,612304) vitamin K-d ( 461) 224 51.2 3.3e-06
XP_005263774 (OMIM: 176860,612283,612304) PREDICTE ( 482) 224 51.2 3.4e-06
XP_016859995 (OMIM: 176860,612283,612304) PREDICTE ( 495) 224 51.2 3.5e-06
NP_003882 (OMIM: 176895,614024) vitamin K-dependen ( 400) 222 50.8 3.8e-06
XP_016873764 (OMIM: 611690) PREDICTED: transmembra ( 364) 221 50.6 4e-06
XP_016876302 (OMIM: 176895,614024) PREDICTED: vita ( 334) 218 50.0 5.4e-06
NP_001243063 (OMIM: 176895,614024) vitamin K-depen ( 422) 218 50.1 6.6e-06
XP_016876301 (OMIM: 176895,614024) PREDICTED: vita ( 467) 218 50.1 7.2e-06
NP_000304 (OMIM: 176880,612336,614514) vitamin K-d ( 676) 212 49.1 2.1e-05
NP_001301006 (OMIM: 176880,612336,614514) vitamin ( 708) 212 49.1 2.2e-05
XP_016859994 (OMIM: 176860,612283,612304) PREDICTE ( 542) 196 46.0 0.00014
XP_006718376 (OMIM: 611690) PREDICTED: transmembra ( 288) 185 43.8 0.00034
NP_000811 (OMIM: 600441) growth arrest-specific pr ( 678) 180 43.1 0.0014
>>NP_001166961 (OMIM: 300935) transmembrane gamma-carbox (218 aa)
initn: 1493 init1: 1493 opt: 1493 Z-score: 1518.3 bits: 288.1 E(85289): 7.9e-78
Smith-Waterman score: 1493; 100.0% identity (100.0% similar) in 218 aa overlap (1-218:1-218)
10 20 30 40 50 60
pF1KB3 MGRVFLTGEKANSILKRYPRANGFFEEIRQGNIERECKEEFCTFEEAREAFENNEKTKEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRVFLTGEKANSILKRYPRANGFFEEIRQGNIERECKEEFCTFEEAREAFENNEKTKEF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 WSTYTKAQQGESNRGSDWFQFYLTFPLIFGLFIILLVIFLIWRCFLRNKTRRQTVTEGHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WSTYTKAQQGESNRGSDWFQFYLTFPLIFGLFIILLVIFLIWRCFLRNKTRRQTVTEGHI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 PFPQHLNIITPPPPPDEVFDSSGLSPGFLGYVVGRSDSVSTRLSNCDPPPTYEEATGQVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFPQHLNIITPPPPPDEVFDSSGLSPGFLGYVVGRSDSVSTRLSNCDPPPTYEEATGQVN
130 140 150 160 170 180
190 200 210
pF1KB3 LQRSETEPHLDPPPEYEDIVNSNSASAIPMVPVVTTIK
::::::::::::::::::::::::::::::::::::::
NP_001 LQRSETEPHLDPPPEYEDIVNSNSASAIPMVPVVTTIK
190 200 210
>>NP_001166960 (OMIM: 300935) transmembrane gamma-carbox (218 aa)
initn: 1493 init1: 1493 opt: 1493 Z-score: 1518.3 bits: 288.1 E(85289): 7.9e-78
Smith-Waterman score: 1493; 100.0% identity (100.0% similar) in 218 aa overlap (1-218:1-218)
10 20 30 40 50 60
pF1KB3 MGRVFLTGEKANSILKRYPRANGFFEEIRQGNIERECKEEFCTFEEAREAFENNEKTKEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRVFLTGEKANSILKRYPRANGFFEEIRQGNIERECKEEFCTFEEAREAFENNEKTKEF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 WSTYTKAQQGESNRGSDWFQFYLTFPLIFGLFIILLVIFLIWRCFLRNKTRRQTVTEGHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WSTYTKAQQGESNRGSDWFQFYLTFPLIFGLFIILLVIFLIWRCFLRNKTRRQTVTEGHI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 PFPQHLNIITPPPPPDEVFDSSGLSPGFLGYVVGRSDSVSTRLSNCDPPPTYEEATGQVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFPQHLNIITPPPPPDEVFDSSGLSPGFLGYVVGRSDSVSTRLSNCDPPPTYEEATGQVN
130 140 150 160 170 180
190 200 210
pF1KB3 LQRSETEPHLDPPPEYEDIVNSNSASAIPMVPVVTTIK
::::::::::::::::::::::::::::::::::::::
NP_001 LQRSETEPHLDPPPEYEDIVNSNSASAIPMVPVVTTIK
190 200 210
>>NP_001135867 (OMIM: 300935) transmembrane gamma-carbox (218 aa)
initn: 1493 init1: 1493 opt: 1493 Z-score: 1518.3 bits: 288.1 E(85289): 7.9e-78
Smith-Waterman score: 1493; 100.0% identity (100.0% similar) in 218 aa overlap (1-218:1-218)
10 20 30 40 50 60
pF1KB3 MGRVFLTGEKANSILKRYPRANGFFEEIRQGNIERECKEEFCTFEEAREAFENNEKTKEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRVFLTGEKANSILKRYPRANGFFEEIRQGNIERECKEEFCTFEEAREAFENNEKTKEF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 WSTYTKAQQGESNRGSDWFQFYLTFPLIFGLFIILLVIFLIWRCFLRNKTRRQTVTEGHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WSTYTKAQQGESNRGSDWFQFYLTFPLIFGLFIILLVIFLIWRCFLRNKTRRQTVTEGHI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 PFPQHLNIITPPPPPDEVFDSSGLSPGFLGYVVGRSDSVSTRLSNCDPPPTYEEATGQVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFPQHLNIITPPPPPDEVFDSSGLSPGFLGYVVGRSDSVSTRLSNCDPPPTYEEATGQVN
130 140 150 160 170 180
190 200 210
pF1KB3 LQRSETEPHLDPPPEYEDIVNSNSASAIPMVPVVTTIK
::::::::::::::::::::::::::::::::::::::
NP_001 LQRSETEPHLDPPPEYEDIVNSNSASAIPMVPVVTTIK
190 200 210
>>NP_000941 (OMIM: 300935) transmembrane gamma-carboxygl (218 aa)
initn: 1493 init1: 1493 opt: 1493 Z-score: 1518.3 bits: 288.1 E(85289): 7.9e-78
Smith-Waterman score: 1493; 100.0% identity (100.0% similar) in 218 aa overlap (1-218:1-218)
10 20 30 40 50 60
pF1KB3 MGRVFLTGEKANSILKRYPRANGFFEEIRQGNIERECKEEFCTFEEAREAFENNEKTKEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGRVFLTGEKANSILKRYPRANGFFEEIRQGNIERECKEEFCTFEEAREAFENNEKTKEF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 WSTYTKAQQGESNRGSDWFQFYLTFPLIFGLFIILLVIFLIWRCFLRNKTRRQTVTEGHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 WSTYTKAQQGESNRGSDWFQFYLTFPLIFGLFIILLVIFLIWRCFLRNKTRRQTVTEGHI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 PFPQHLNIITPPPPPDEVFDSSGLSPGFLGYVVGRSDSVSTRLSNCDPPPTYEEATGQVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PFPQHLNIITPPPPPDEVFDSSGLSPGFLGYVVGRSDSVSTRLSNCDPPPTYEEATGQVN
130 140 150 160 170 180
190 200 210
pF1KB3 LQRSETEPHLDPPPEYEDIVNSNSASAIPMVPVVTTIK
::::::::::::::::::::::::::::::::::::::
NP_000 LQRSETEPHLDPPPEYEDIVNSNSASAIPMVPVVTTIK
190 200 210
>>NP_001166957 (OMIM: 300935) transmembrane gamma-carbox (82 aa)
initn: 381 init1: 381 opt: 381 Z-score: 402.4 bits: 80.2 E(85289): 1.1e-15
Smith-Waterman score: 381; 100.0% identity (100.0% similar) in 57 aa overlap (1-57:1-57)
10 20 30 40 50 60
pF1KB3 MGRVFLTGEKANSILKRYPRANGFFEEIRQGNIERECKEEFCTFEEAREAFENNEKTKEF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRVFLTGEKANSILKRYPRANGFFEEIRQGNIERECKEEFCTFEEAREAFENNEKTGLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 WSTYTKAQQGESNRGSDWFQFYLTFPLIFGLFIILLVIFLIWRCFLRNKTRRQTVTEGHI
NP_001 LLPRLECSCEHGSLQPQLPVPK
70 80
>>NP_076987 (OMIM: 300685) transmembrane gamma-carboxygl (231 aa)
initn: 509 init1: 360 opt: 362 Z-score: 376.3 bits: 76.8 E(85289): 3.2e-14
Smith-Waterman score: 443; 38.1% identity (65.9% similar) in 226 aa overlap (4-203:3-226)
10 20 30 40 50 60
pF1KB3 MGRVFLTGEKANSILKRYPRANGFFEEIRQGNIERECKEEFCTFEEAREAFENNEKTKEF
::: .. :.:.:::.:::: :.::.:::.::::: ::.:..::..:.:::.::: ::
NP_076 MAVFLEAKDAHSVLKRFPRANEFLEELRQGTIERECMEEICSYEEVKEVFENKEKTMEF
10 20 30 40 50
70 80 90 100 110
pF1KB3 WSTYTKAQQG--ESNRGSDWFQFYLTFPLIFGLFIILLVIFLIWRCFLRNKTR-------
:. : .: . . ...:: .:.. ::. ..:....:.:::: :.. ::
NP_076 WKGYPNAVYSVRDPSQSSD--AMYVVVPLLGVALLIVIALFIIWRCQLQKATRHHPSYAQ
60 70 80 90 100 110
120 130 140 150 160
pF1KB3 -RQTVTE-GH-IP----FPQHLNIITPPPPPDEVFDSSG--LSPGFLGYVVGRSDSVS--
: ... :: .: . .. : :. .: :.:. : .. : .:.
NP_076 NRYLASRAGHTLPRVMVYRGTVHSQGEPSGHREAANSPQVVLGPSRGGRTTVRLESTLYL
120 130 140 150 160 170
170 180 190 200 210
pF1KB3 -----TRLSNCDPPPTYEEATG-QVNLQRSETEPHLDPPPEYEDIVNSNSASAIPMVPVV
.:::. :::.:::.:. : . .. . . ::::.::.:: .:
NP_076 PELSLSRLSSTTPPPSYEEVTAPQESSSEEASVSYSDPPPKYEEIVAANPGADK
180 190 200 210 220 230
pF1KB3 TTIK
>>XP_005274804 (OMIM: 300685) PREDICTED: transmembrane g (231 aa)
initn: 509 init1: 360 opt: 362 Z-score: 376.3 bits: 76.8 E(85289): 3.2e-14
Smith-Waterman score: 443; 38.1% identity (65.9% similar) in 226 aa overlap (4-203:3-226)
10 20 30 40 50 60
pF1KB3 MGRVFLTGEKANSILKRYPRANGFFEEIRQGNIERECKEEFCTFEEAREAFENNEKTKEF
::: .. :.:.:::.:::: :.::.:::.::::: ::.:..::..:.:::.::: ::
XP_005 MAVFLEAKDAHSVLKRFPRANEFLEELRQGTIERECMEEICSYEEVKEVFENKEKTMEF
10 20 30 40 50
70 80 90 100 110
pF1KB3 WSTYTKAQQG--ESNRGSDWFQFYLTFPLIFGLFIILLVIFLIWRCFLRNKTR-------
:. : .: . . ...:: .:.. ::. ..:....:.:::: :.. ::
XP_005 WKGYPNAVYSVRDPSQSSD--AMYVVVPLLGVALLIVIALFIIWRCQLQKATRHHPSYAQ
60 70 80 90 100 110
120 130 140 150 160
pF1KB3 -RQTVTE-GH-IP----FPQHLNIITPPPPPDEVFDSSG--LSPGFLGYVVGRSDSVS--
: ... :: .: . .. : :. .: :.:. : .. : .:.
XP_005 NRYLASRAGHTLPRVMVYRGTVHSQGEPSGHREAANSPQVVLGPSRGGRTTVRLESTLYL
120 130 140 150 160 170
170 180 190 200 210
pF1KB3 -----TRLSNCDPPPTYEEATG-QVNLQRSETEPHLDPPPEYEDIVNSNSASAIPMVPVV
.:::. :::.:::.:. : . .. . . ::::.::.:: .:
XP_005 PELSLSRLSSTTPPPSYEEVTAPQESSSEEASVSYSDPPPKYEEIVAANPGADK
180 190 200 210 220 230
pF1KB3 TTIK
>>XP_011529499 (OMIM: 300685) PREDICTED: transmembrane g (231 aa)
initn: 509 init1: 360 opt: 362 Z-score: 376.3 bits: 76.8 E(85289): 3.2e-14
Smith-Waterman score: 443; 38.1% identity (65.9% similar) in 226 aa overlap (4-203:3-226)
10 20 30 40 50 60
pF1KB3 MGRVFLTGEKANSILKRYPRANGFFEEIRQGNIERECKEEFCTFEEAREAFENNEKTKEF
::: .. :.:.:::.:::: :.::.:::.::::: ::.:..::..:.:::.::: ::
XP_011 MAVFLEAKDAHSVLKRFPRANEFLEELRQGTIERECMEEICSYEEVKEVFENKEKTMEF
10 20 30 40 50
70 80 90 100 110
pF1KB3 WSTYTKAQQG--ESNRGSDWFQFYLTFPLIFGLFIILLVIFLIWRCFLRNKTR-------
:. : .: . . ...:: .:.. ::. ..:....:.:::: :.. ::
XP_011 WKGYPNAVYSVRDPSQSSD--AMYVVVPLLGVALLIVIALFIIWRCQLQKATRHHPSYAQ
60 70 80 90 100 110
120 130 140 150 160
pF1KB3 -RQTVTE-GH-IP----FPQHLNIITPPPPPDEVFDSSG--LSPGFLGYVVGRSDSVS--
: ... :: .: . .. : :. .: :.:. : .. : .:.
XP_011 NRYLASRAGHTLPRVMVYRGTVHSQGEPSGHREAANSPQVVLGPSRGGRTTVRLESTLYL
120 130 140 150 160 170
170 180 190 200 210
pF1KB3 -----TRLSNCDPPPTYEEATG-QVNLQRSETEPHLDPPPEYEDIVNSNSASAIPMVPVV
.:::. :::.:::.:. : . .. . . ::::.::.:: .:
XP_011 PELSLSRLSSTTPPPSYEEVTAPQESSSEEASVSYSDPPPKYEEIVAANPGADK
180 190 200 210 220 230
pF1KB3 TTIK
>>NP_000122 (OMIM: 227500,608446,613878) coagulation fac (466 aa)
initn: 273 init1: 273 opt: 287 Z-score: 296.0 bits: 63.0 E(85289): 9.5e-10
Smith-Waterman score: 287; 51.6% identity (74.7% similar) in 91 aa overlap (3-87:43-133)
10 20 30
pF1KB3 MGRVFLTGEKANSILKRYPRANGFFEEIRQGN
:::.: :.:...:.: :::.:.::.: :.
NP_000 LGLQGCLAAGGVAKASGGETRDMPWKPGPHRVFVTQEEAHGVLHRRRRANAFLEELRPGS
20 30 40 50 60 70
40 50 60 70 80
pF1KB3 IERECKEEFCTFEEAREAFENNEKTKEFWSTYTKAQQGES----NRGS--DWFQFYLTFP
.::::::: :.:::::: :.. :.:: :: .:. ..: : : :: : .: :. :
NP_000 LERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFC
80 90 100 110 120 130
90 100 110 120 130 140
pF1KB3 LIFGLFIILLVIFLIWRCFLRNKTRRQTVTEGHIPFPQHLNIITPPPPPDEVFDSSGLSP
:
NP_000 LPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVE
140 150 160 170 180 190
>>XP_006720026 (OMIM: 227500,608446,613878) PREDICTED: c (412 aa)
initn: 266 init1: 266 opt: 281 Z-score: 290.8 bits: 61.8 E(85289): 1.9e-09
Smith-Waterman score: 281; 49.5% identity (74.2% similar) in 93 aa overlap (1-87:34-126)
10 20 30
pF1KB3 MGRVFLTGEKANSILKRYPRANGFFEEIRQ
.. ::.: :.:...:.: :::.:.::.:
XP_006 VNRQGQHCRDFIMVSQALRLLCLLLGLQGCLAAVFVTQEEAHGVLHRRRRANAFLEELRP
10 20 30 40 50 60
40 50 60 70 80
pF1KB3 GNIERECKEEFCTFEEAREAFENNEKTKEFWSTYTKAQQGES----NRGS--DWFQFYLT
:..::::::: :.:::::: :.. :.:: :: .:. ..: : : :: : .: :.
XP_006 GSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYIC
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB3 FPLIFGLFIILLVIFLIWRCFLRNKTRRQTVTEGHIPFPQHLNIITPPPPPDEVFDSSGL
: :
XP_006 FCLPAFEGRNCETLEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQL
130 140 150 160 170 180
218 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:51:43 2016 done: Sat Nov 5 04:51:44 2016
Total Scan time: 6.230 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]