Result of FASTA (omim) for
pFN21AE0977
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0977, 571 aa
1>>>pF1KE0977 571 - 571 aa - 571 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.2547+/-0.000483; mu= 1.8399+/- 0.029
mean_var=612.4654+/-136.517, 0's: 0 Z-trim(119.8): 1262 B-trim: 36 in 1/60
Lambda= 0.051824
statistics sampled from 32268 (34163) to 32268 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.401), width: 16
Scan time: 11.340
The best scores are: opt bits E(85289)
XP_006710350 (OMIM: 604746) PREDICTED: dual specif ( 571) 3899 307.5 7.8e-83
XP_011538799 (OMIM: 604746) PREDICTED: dual specif ( 571) 3899 307.5 7.8e-83
NP_009101 (OMIM: 604746) dual specificity testis-s ( 571) 3899 307.5 7.8e-83
NP_001307729 (OMIM: 604746) dual specificity testi ( 488) 3340 265.5 2.8e-70
XP_016855536 (OMIM: 604746) PREDICTED: dual specif ( 522) 2707 218.3 5e-56
XP_005270412 (OMIM: 604746) PREDICTED: dual specif ( 522) 2707 218.3 5e-56
XP_016855537 (OMIM: 604746) PREDICTED: dual specif ( 363) 2519 203.9 7.2e-52
XP_016855538 (OMIM: 604746) PREDICTED: dual specif ( 363) 2519 203.9 7.2e-52
XP_011538802 (OMIM: 604746) PREDICTED: dual specif ( 301) 1990 164.2 5.3e-40
NP_006276 (OMIM: 601782) dual specificity testis-s ( 626) 1336 115.9 3.9e-25
NP_001305159 (OMIM: 601782) dual specificity testi ( 466) 487 52.2 4.4e-06
XP_005269197 (OMIM: 600447) PREDICTED: mitogen-act ( 453) 418 47.0 0.00015
XP_016875445 (OMIM: 600447) PREDICTED: mitogen-act ( 859) 418 47.5 0.00021
NP_006292 (OMIM: 600447) mitogen-activated protein ( 859) 418 47.5 0.00021
NP_005966 (OMIM: 602004) protein-tyrosine kinase 6 ( 451) 412 46.6 0.00021
XP_011537027 (OMIM: 600447) PREDICTED: mitogen-act ( 892) 418 47.5 0.00021
XP_006719651 (OMIM: 600447) PREDICTED: mitogen-act ( 892) 418 47.5 0.00021
NP_001180440 (OMIM: 600447) mitogen-activated prot ( 892) 418 47.5 0.00021
XP_005269195 (OMIM: 600447) PREDICTED: mitogen-act ( 892) 418 47.5 0.00021
XP_016858657 (OMIM: 602255) PREDICTED: serine/thre ( 365) 407 46.0 0.00025
XP_016858658 (OMIM: 602255) PREDICTED: serine/thre ( 365) 407 46.0 0.00025
NP_001191355 (OMIM: 601329) LIM domain kinase 1 is ( 613) 410 46.6 0.00027
NP_002305 (OMIM: 601329) LIM domain kinase 1 isofo ( 647) 410 46.7 0.00028
XP_011533958 (OMIM: 606573) PREDICTED: tyrosine-pr ( 392) 404 45.9 0.0003
XP_005266938 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 404 46.1 0.00034
XP_005266937 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 404 46.1 0.00034
XP_016866134 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 404 46.1 0.00034
XP_011533955 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 404 46.1 0.00034
XP_011533956 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 404 46.1 0.00034
NP_002022 (OMIM: 606573) tyrosine-protein kinase F ( 505) 404 46.1 0.00034
XP_011533957 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 404 46.1 0.00034
XP_005266939 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505) 404 46.1 0.00034
NP_005148 (OMIM: 189980) tyrosine-protein kinase A (1130) 410 47.1 0.00036
NP_009297 (OMIM: 189980) tyrosine-protein kinase A (1149) 410 47.1 0.00037
XP_011508798 (OMIM: 602255) PREDICTED: serine/thre ( 334) 397 45.2 0.0004
NP_057952 (OMIM: 601988) LIM domain kinase 2 isofo ( 617) 401 46.0 0.00043
NP_005560 (OMIM: 601988) LIM domain kinase 2 isofo ( 638) 401 46.0 0.00044
XP_016858654 (OMIM: 604705,613862) PREDICTED: tyro ( 594) 400 45.9 0.00045
NP_001026971 (OMIM: 601988) LIM domain kinase 2 is ( 686) 401 46.1 0.00046
XP_011508792 (OMIM: 604705,613862) PREDICTED: tyro ( 936) 400 46.2 0.00056
XP_016858653 (OMIM: 604705,613862) PREDICTED: tyro ( 936) 400 46.2 0.00056
XP_011508795 (OMIM: 602255) PREDICTED: serine/thre ( 376) 391 44.9 0.00057
NP_006334 (OMIM: 604705,613862) tyrosine-protein k ( 999) 400 46.3 0.00058
NP_001258907 (OMIM: 602255) serine/threonine-prote ( 426) 391 45.0 0.00061
NP_001258906 (OMIM: 602255) serine/threonine-prote ( 426) 391 45.0 0.00061
NP_006365 (OMIM: 602255) serine/threonine-protein ( 426) 391 45.0 0.00061
XP_005254222 (OMIM: 124095) PREDICTED: tyrosine-pr ( 450) 391 45.0 0.00063
NP_001120662 (OMIM: 124095) tyrosine-protein kinas ( 450) 391 45.0 0.00063
NP_004374 (OMIM: 124095) tyrosine-protein kinase C ( 450) 391 45.0 0.00063
XP_016877414 (OMIM: 124095) PREDICTED: tyrosine-pr ( 450) 391 45.0 0.00063
>>XP_006710350 (OMIM: 604746) PREDICTED: dual specificit (571 aa)
initn: 3899 init1: 3899 opt: 3899 Z-score: 1608.1 bits: 307.5 E(85289): 7.8e-83
Smith-Waterman score: 3899; 100.0% identity (100.0% similar) in 571 aa overlap (1-571:1-571)
10 20 30 40 50 60
pF1KE0 MDRSKRNSIAGFPPRVERLEEFEGGGGGEGNVSQVGRVWPSSYRALISAFSRLTRLDDFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MDRSKRNSIAGFPPRVERLEEFEGGGGGEGNVSQVGRVWPSSYRALISAFSRLTRLDDFT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 CEKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CEKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VHQGQLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VHQGQLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 NCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKADVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKADVF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKLRP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 SFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCPRR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 TIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKIKFFDLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKIKFFDLPS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 KSVISLVFDLDAPGPGTMPLADWQEPLAPPIRRWRSLPGSPEFLHQEACPFVGREESLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSVISLVFDLDAPGPGTMPLADWQEPLAPPIRRWRSLPGSPEFLHQEACPFVGREESLSD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 GPPPRLSSLKYRVKEIPPFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSPCPAGASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPPPRLSSLKYRVKEIPPFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSPCPAGASE
490 500 510 520 530 540
550 560 570
pF1KE0 EMEVEERPAGSTPATFSTSGIGLQTQGKQDG
:::::::::::::::::::::::::::::::
XP_006 EMEVEERPAGSTPATFSTSGIGLQTQGKQDG
550 560 570
>>XP_011538799 (OMIM: 604746) PREDICTED: dual specificit (571 aa)
initn: 3899 init1: 3899 opt: 3899 Z-score: 1608.1 bits: 307.5 E(85289): 7.8e-83
Smith-Waterman score: 3899; 100.0% identity (100.0% similar) in 571 aa overlap (1-571:1-571)
10 20 30 40 50 60
pF1KE0 MDRSKRNSIAGFPPRVERLEEFEGGGGGEGNVSQVGRVWPSSYRALISAFSRLTRLDDFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDRSKRNSIAGFPPRVERLEEFEGGGGGEGNVSQVGRVWPSSYRALISAFSRLTRLDDFT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 CEKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VHQGQLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHQGQLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 NCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKADVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKADVF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKLRP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 SFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCPRR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 TIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKIKFFDLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKIKFFDLPS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 KSVISLVFDLDAPGPGTMPLADWQEPLAPPIRRWRSLPGSPEFLHQEACPFVGREESLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSVISLVFDLDAPGPGTMPLADWQEPLAPPIRRWRSLPGSPEFLHQEACPFVGREESLSD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 GPPPRLSSLKYRVKEIPPFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSPCPAGASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPPPRLSSLKYRVKEIPPFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSPCPAGASE
490 500 510 520 530 540
550 560 570
pF1KE0 EMEVEERPAGSTPATFSTSGIGLQTQGKQDG
:::::::::::::::::::::::::::::::
XP_011 EMEVEERPAGSTPATFSTSGIGLQTQGKQDG
550 560 570
>>NP_009101 (OMIM: 604746) dual specificity testis-speci (571 aa)
initn: 3899 init1: 3899 opt: 3899 Z-score: 1608.1 bits: 307.5 E(85289): 7.8e-83
Smith-Waterman score: 3899; 100.0% identity (100.0% similar) in 571 aa overlap (1-571:1-571)
10 20 30 40 50 60
pF1KE0 MDRSKRNSIAGFPPRVERLEEFEGGGGGEGNVSQVGRVWPSSYRALISAFSRLTRLDDFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MDRSKRNSIAGFPPRVERLEEFEGGGGGEGNVSQVGRVWPSSYRALISAFSRLTRLDDFT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 CEKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 CEKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VHQGQLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VHQGQLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 NCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKADVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 NCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKADVF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKLRP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 SFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCPRR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 TIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKIKFFDLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKIKFFDLPS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 KSVISLVFDLDAPGPGTMPLADWQEPLAPPIRRWRSLPGSPEFLHQEACPFVGREESLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KSVISLVFDLDAPGPGTMPLADWQEPLAPPIRRWRSLPGSPEFLHQEACPFVGREESLSD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 GPPPRLSSLKYRVKEIPPFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSPCPAGASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GPPPRLSSLKYRVKEIPPFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSPCPAGASE
490 500 510 520 530 540
550 560 570
pF1KE0 EMEVEERPAGSTPATFSTSGIGLQTQGKQDG
:::::::::::::::::::::::::::::::
NP_009 EMEVEERPAGSTPATFSTSGIGLQTQGKQDG
550 560 570
>>NP_001307729 (OMIM: 604746) dual specificity testis-sp (488 aa)
initn: 3340 init1: 3340 opt: 3340 Z-score: 1382.8 bits: 265.5 E(85289): 2.8e-70
Smith-Waterman score: 3340; 100.0% identity (100.0% similar) in 488 aa overlap (84-571:1-488)
60 70 80 90 100 110
pF1KE0 TRLDDFTCEKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNI
::::::::::::::::::::::::::::::
NP_001 MALKMNTLSSNRANMLKEVQLMNRLSHPNI
10 20 30
120 130 140 150 160 170
pF1KE0 LRFMGVCVHQGQLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRFMGVCVHQGQLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIF
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE0 HRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPY
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE0 NEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCN
160 170 180 190 200 210
300 310 320 330 340 350
pF1KE0 MDPKLRPSFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDPKLRPSFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPH
220 230 240 250 260 270
360 370 380 390 400 410
pF1KE0 KSPCPRRTIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSPCPRRTIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKI
280 290 300 310 320 330
420 430 440 450 460 470
pF1KE0 KFFDLPSKSVISLVFDLDAPGPGTMPLADWQEPLAPPIRRWRSLPGSPEFLHQEACPFVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFFDLPSKSVISLVFDLDAPGPGTMPLADWQEPLAPPIRRWRSLPGSPEFLHQEACPFVG
340 350 360 370 380 390
480 490 500 510 520 530
pF1KE0 REESLSDGPPPRLSSLKYRVKEIPPFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REESLSDGPPPRLSSLKYRVKEIPPFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSP
400 410 420 430 440 450
540 550 560 570
pF1KE0 CPAGASEEMEVEERPAGSTPATFSTSGIGLQTQGKQDG
::::::::::::::::::::::::::::::::::::::
NP_001 CPAGASEEMEVEERPAGSTPATFSTSGIGLQTQGKQDG
460 470 480
>>XP_016855536 (OMIM: 604746) PREDICTED: dual specificit (522 aa)
initn: 2706 init1: 2706 opt: 2707 Z-score: 1126.8 bits: 218.3 E(85289): 5e-56
Smith-Waterman score: 3467; 91.4% identity (91.4% similar) in 571 aa overlap (1-571:1-522)
10 20 30 40 50 60
pF1KE0 MDRSKRNSIAGFPPRVERLEEFEGGGGGEGNVSQVGRVWPSSYRALISAFSRLTRLDDFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDRSKRNSIAGFPPRVERLEEFEGGGGGEGNVSQVGRVWPSSYRALISAFSRLTRLDDFT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 CEKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CEKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VHQGQLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSK
:::::::::::
XP_016 VHQGQLHALTE-------------------------------------------------
130
190 200 210 220 230 240
pF1KE0 NCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKADVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKADVF
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE0 SYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKLRP
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE0 SFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCPRR
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE0 TIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKIKFFDLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKIKFFDLPS
320 330 340 350 360 370
430 440 450 460 470 480
pF1KE0 KSVISLVFDLDAPGPGTMPLADWQEPLAPPIRRWRSLPGSPEFLHQEACPFVGREESLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSVISLVFDLDAPGPGTMPLADWQEPLAPPIRRWRSLPGSPEFLHQEACPFVGREESLSD
380 390 400 410 420 430
490 500 510 520 530 540
pF1KE0 GPPPRLSSLKYRVKEIPPFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSPCPAGASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPPPRLSSLKYRVKEIPPFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSPCPAGASE
440 450 460 470 480 490
550 560 570
pF1KE0 EMEVEERPAGSTPATFSTSGIGLQTQGKQDG
:::::::::::::::::::::::::::::::
XP_016 EMEVEERPAGSTPATFSTSGIGLQTQGKQDG
500 510 520
>>XP_005270412 (OMIM: 604746) PREDICTED: dual specificit (522 aa)
initn: 2706 init1: 2706 opt: 2707 Z-score: 1126.8 bits: 218.3 E(85289): 5e-56
Smith-Waterman score: 3467; 91.4% identity (91.4% similar) in 571 aa overlap (1-571:1-522)
10 20 30 40 50 60
pF1KE0 MDRSKRNSIAGFPPRVERLEEFEGGGGGEGNVSQVGRVWPSSYRALISAFSRLTRLDDFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDRSKRNSIAGFPPRVERLEEFEGGGGGEGNVSQVGRVWPSSYRALISAFSRLTRLDDFT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 CEKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CEKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VHQGQLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSK
:::::::::::
XP_005 VHQGQLHALTE-------------------------------------------------
130
190 200 210 220 230 240
pF1KE0 NCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKADVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKADVF
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE0 SYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKLRP
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE0 SFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCPRR
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE0 TIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKIKFFDLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKIKFFDLPS
320 330 340 350 360 370
430 440 450 460 470 480
pF1KE0 KSVISLVFDLDAPGPGTMPLADWQEPLAPPIRRWRSLPGSPEFLHQEACPFVGREESLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSVISLVFDLDAPGPGTMPLADWQEPLAPPIRRWRSLPGSPEFLHQEACPFVGREESLSD
380 390 400 410 420 430
490 500 510 520 530 540
pF1KE0 GPPPRLSSLKYRVKEIPPFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSPCPAGASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPPPRLSSLKYRVKEIPPFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSPCPAGASE
440 450 460 470 480 490
550 560 570
pF1KE0 EMEVEERPAGSTPATFSTSGIGLQTQGKQDG
:::::::::::::::::::::::::::::::
XP_005 EMEVEERPAGSTPATFSTSGIGLQTQGKQDG
500 510 520
>>XP_016855537 (OMIM: 604746) PREDICTED: dual specificit (363 aa)
initn: 2519 init1: 2519 opt: 2519 Z-score: 1052.2 bits: 203.9 E(85289): 7.2e-52
Smith-Waterman score: 2519; 100.0% identity (100.0% similar) in 363 aa overlap (209-571:1-363)
180 190 200 210 220 230
pF1KE0 SKNCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKAD
::::::::::::::::::::::::::::::
XP_016 MGSEKLAVVGSPFWMAPEVLRDEPYNEKAD
10 20 30
240 250 260 270 280 290
pF1KE0 VFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKL
40 50 60 70 80 90
300 310 320 330 340 350
pF1KE0 RPSFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPSFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCP
100 110 120 130 140 150
360 370 380 390 400 410
pF1KE0 RRTIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKIKFFDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRTIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKIKFFDL
160 170 180 190 200 210
420 430 440 450 460 470
pF1KE0 PSKSVISLVFDLDAPGPGTMPLADWQEPLAPPIRRWRSLPGSPEFLHQEACPFVGREESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSKSVISLVFDLDAPGPGTMPLADWQEPLAPPIRRWRSLPGSPEFLHQEACPFVGREESL
220 230 240 250 260 270
480 490 500 510 520 530
pF1KE0 SDGPPPRLSSLKYRVKEIPPFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSPCPAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDGPPPRLSSLKYRVKEIPPFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSPCPAGA
280 290 300 310 320 330
540 550 560 570
pF1KE0 SEEMEVEERPAGSTPATFSTSGIGLQTQGKQDG
:::::::::::::::::::::::::::::::::
XP_016 SEEMEVEERPAGSTPATFSTSGIGLQTQGKQDG
340 350 360
>>XP_016855538 (OMIM: 604746) PREDICTED: dual specificit (363 aa)
initn: 2519 init1: 2519 opt: 2519 Z-score: 1052.2 bits: 203.9 E(85289): 7.2e-52
Smith-Waterman score: 2519; 100.0% identity (100.0% similar) in 363 aa overlap (209-571:1-363)
180 190 200 210 220 230
pF1KE0 SKNCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKAD
::::::::::::::::::::::::::::::
XP_016 MGSEKLAVVGSPFWMAPEVLRDEPYNEKAD
10 20 30
240 250 260 270 280 290
pF1KE0 VFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKL
40 50 60 70 80 90
300 310 320 330 340 350
pF1KE0 RPSFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPSFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCP
100 110 120 130 140 150
360 370 380 390 400 410
pF1KE0 RRTIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKIKFFDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRTIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKIKFFDL
160 170 180 190 200 210
420 430 440 450 460 470
pF1KE0 PSKSVISLVFDLDAPGPGTMPLADWQEPLAPPIRRWRSLPGSPEFLHQEACPFVGREESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSKSVISLVFDLDAPGPGTMPLADWQEPLAPPIRRWRSLPGSPEFLHQEACPFVGREESL
220 230 240 250 260 270
480 490 500 510 520 530
pF1KE0 SDGPPPRLSSLKYRVKEIPPFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSPCPAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDGPPPRLSSLKYRVKEIPPFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSPCPAGA
280 290 300 310 320 330
540 550 560 570
pF1KE0 SEEMEVEERPAGSTPATFSTSGIGLQTQGKQDG
:::::::::::::::::::::::::::::::::
XP_016 SEEMEVEERPAGSTPATFSTSGIGLQTQGKQDG
340 350 360
>>XP_011538802 (OMIM: 604746) PREDICTED: dual specificit (301 aa)
initn: 1990 init1: 1990 opt: 1990 Z-score: 839.2 bits: 164.2 E(85289): 5.3e-40
Smith-Waterman score: 1990; 100.0% identity (100.0% similar) in 293 aa overlap (1-293:1-293)
10 20 30 40 50 60
pF1KE0 MDRSKRNSIAGFPPRVERLEEFEGGGGGEGNVSQVGRVWPSSYRALISAFSRLTRLDDFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDRSKRNSIAGFPPRVERLEEFEGGGGGEGNVSQVGRVWPSSYRALISAFSRLTRLDDFT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 CEKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VHQGQLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHQGQLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 NCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKADVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKADVF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKLRP
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNDSWRKHL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 SFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCPRR
XP_011 G
>>NP_006276 (OMIM: 601782) dual specificity testis-speci (626 aa)
initn: 1189 init1: 752 opt: 1336 Z-score: 572.2 bits: 115.9 E(85289): 3.9e-25
Smith-Waterman score: 1547; 54.2% identity (68.8% similar) in 509 aa overlap (25-516:25-500)
10 20 30 40 50 60
pF1KE0 MDRSKRNSIAGFPPRVERLEEFEGGGGGEGNVSQVGRVWPSSYRALISAFSRLTRLDDFT
: :: :. :: ::::::: :: : :.:.:::
NP_006 MAGERPPLRGPGPGPGEVPGEGPPGPGGTGGGPGRGR--PSSYRALRSAVSSLARVDDFH
10 20 30 40 50
70 80 90 100 110
pF1KE0 C-EKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGV
: ::::.::::::.::::: :::::.:::: : :::.: :.:::::::: ::::::::::
NP_006 CAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRGNTLREVQLMNRLRHPNILRFMGV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 CVHQGQLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTS
:::::::::::::.:.:.:::::.: : : ::..:: ::: :: ::: ::.:::::::
NP_006 CVHQGQLHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIARGLRYLHSKGVFHRDLTS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 KNCLIKRDENGYSAVVADFGLAEKIPDVSMGSEK--LAVVGSPFWMAPEVLRDEPYNEKA
::::..:.. :..:::.::::::::: :..: :::::::.:::::::: : :.:::
NP_006 KNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 DVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGD-CPPDFLQLTFNCCNMDP
:::..::.:::.:::. ::::::::::.:::: ::. .::: :: :: :...:::..:
NP_006 DVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGDDCPLPFLLLAIHCCNLEP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 KLRPSFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSP
. : :.:: . :: :: .: : : .: : . : .. . .:. :
NP_006 STRAPFTEITQHLEWILEQLPEPA--------PLTRTALTHNQGSVARGGPSATLPR--P
300 310 320 330 340
360 370 380 390 400 410
pF1KE0 CPRRTIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKIKFF
:: ::::.::.: :: .: : : : .::::: :.:: :::::..
NP_006 DPR----LSRSRSDLFL--PP------SPESPPNWGDNLT-RVNPFSLREDLRGGKIKLL
350 360 370 380 390
420 430 440 450 460 470
pF1KE0 DLPSKSVISLVFDLDAPGPGT-MPLADWQEPLA-P--PIRRWRSLPGSPEFLHQEACPFV
: ::: :. :: .: :.: .::. : :. : : :: ::::.:::. .. .
NP_006 DTPSKPVLPLVP--PSPFPSTQLPLVTTPETLVQPGTPARRCRSLPSSPELPRRMETALP
400 410 420 430 440 450
480 490 500 510 520
pF1KE0 GREESLSDGPPPRLSSLKYRVK-------EIPPFRASALPAAQAHEAM--DCSILQEENG
: ::: : . ... :: : :: : : . . ::
NP_006 G------PGPPAVGPSAEEKMECEGSSPEPEPPGPAPQLPLAVATDNFISTCSSASQPWS
460 470 480 490 500
530 540 550 560 570
pF1KE0 FGSRPQGTSPCPAGASEEMEVEERPAGSTPATFSTSGIGLQTQGKQDG
NP_006 PRSGPVLNNNPPAVVVNSPQGWAGEPWNRAQHSLPRAAALERTEPSPPPSAPREPDEGLP
510 520 530 540 550 560
571 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:46:23 2016 done: Sat Nov 5 04:46:24 2016
Total Scan time: 11.340 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]