Result of FASTA (omim) for
pFN21AE0809
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0809, 335 aa
1>>>pF1KE0809 335 - 335 aa - 335 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 3.7903+/-0.000432; mu= 25.1546+/- 0.027
mean_var=108.0256+/-31.504, 0's: 0 Z-trim(110.8): 467 B-trim: 1130 in 1/51
Lambda= 0.123399
statistics sampled from 18606 (19263) to 18606 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.594), E-opt: 0.2 (0.226), width: 16
Scan time: 7.120
The best scores are: opt bits E(85289)
NP_848566 (OMIM: 300513) glucose-dependent insulin ( 335) 2192 401.6 1.2e-111
NP_000665 (OMIM: 102775) adenosine receptor A1 [Ho ( 326) 317 67.8 3.7e-11
NP_001041695 (OMIM: 102775) adenosine receptor A1 ( 326) 317 67.8 3.7e-11
NP_071640 (OMIM: 142703) histamine H2 receptor iso ( 359) 316 67.7 4.4e-11
XP_006714928 (OMIM: 142703) PREDICTED: histamine H ( 362) 316 67.7 4.4e-11
NP_001124527 (OMIM: 142703) histamine H2 receptor ( 397) 316 67.7 4.6e-11
XP_006714927 (OMIM: 142703) PREDICTED: histamine H ( 422) 316 67.8 4.7e-11
XP_011532851 (OMIM: 142703) PREDICTED: histamine H ( 422) 316 67.8 4.7e-11
XP_016864915 (OMIM: 142703) PREDICTED: histamine H ( 422) 316 67.8 4.7e-11
XP_005265961 (OMIM: 142703) PREDICTED: histamine H ( 422) 316 67.8 4.7e-11
XP_011532850 (OMIM: 142703) PREDICTED: histamine H ( 422) 316 67.8 4.7e-11
NP_778227 (OMIM: 608282) trace amine-associated re ( 348) 293 63.5 7.4e-10
NP_001307659 (OMIM: 601974) sphingosine 1-phosphat ( 382) 284 62.0 2.3e-09
NP_001391 (OMIM: 601974) sphingosine 1-phosphate r ( 382) 284 62.0 2.3e-09
NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 281 61.5 3.5e-09
XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 281 61.5 3.5e-09
XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 281 61.5 3.5e-09
XP_011528651 (OMIM: 182453) PREDICTED: somatostati ( 418) 281 61.5 3.5e-09
XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 281 61.5 3.5e-09
NP_001042 (OMIM: 182453) somatostatin receptor typ ( 418) 281 61.5 3.5e-09
XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 281 61.5 3.5e-09
NP_778237 (OMIM: 608923) trace amine-associated re ( 345) 267 58.9 1.8e-08
NP_000668 (OMIM: 600445) adenosine receptor A3 iso ( 318) 266 58.7 2e-08
NP_005675 (OMIM: 604106) probable G-protein couple ( 361) 266 58.8 2.1e-08
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 262 58.1 3.5e-08
NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 257 57.2 6.5e-08
XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 257 57.2 6.5e-08
NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 257 57.2 6.5e-08
NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 257 57.2 6.5e-08
XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 257 57.2 6.6e-08
XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 257 57.2 6.6e-08
XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 257 57.2 6.6e-08
NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 257 57.2 6.7e-08
NP_001159687 (OMIM: 605146) sphingosine 1-phosphat ( 398) 256 57.1 7.6e-08
NP_110387 (OMIM: 605146) sphingosine 1-phosphate r ( 398) 256 57.1 7.6e-08
XP_005251990 (OMIM: 601909) PREDICTED: probable G- ( 349) 254 56.6 9.1e-08
NP_005285 (OMIM: 601909) probable G-protein couple ( 349) 254 56.6 9.1e-08
XP_016872446 (OMIM: 606665) PREDICTED: melanopsin ( 405) 252 56.4 1.2e-07
NP_000862 (OMIM: 601109) 5-hydroxytryptamine recep ( 440) 252 56.4 1.3e-07
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 252 56.5 1.3e-07
NP_001025186 (OMIM: 606665) melanopsin isoform 2 [ ( 489) 252 56.5 1.4e-07
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 252 56.6 1.4e-07
XP_016872444 (OMIM: 606665) PREDICTED: melanopsin ( 539) 252 56.6 1.4e-07
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 249 55.8 1.8e-07
NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 249 55.8 1.8e-07
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 249 55.8 1.8e-07
XP_016883344 (OMIM: 602548) PREDICTED: nociceptin ( 365) 248 55.6 1.9e-07
NP_001305783 (OMIM: 602548) nociceptin receptor is ( 365) 248 55.6 1.9e-07
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic ( 477) 249 56.0 2e-07
NP_001091682 (OMIM: 600167) histamine H1 receptor ( 487) 249 56.0 2e-07
>>NP_848566 (OMIM: 300513) glucose-dependent insulinotro (335 aa)
initn: 2192 init1: 2192 opt: 2192 Z-score: 2125.2 bits: 401.6 E(85289): 1.2e-111
Smith-Waterman score: 2192; 100.0% identity (100.0% similar) in 335 aa overlap (1-335:1-335)
10 20 30 40 50 60
pF1KE0 MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 LLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 VAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 FVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 FVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 FLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 FLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKV
250 260 270 280 290 300
310 320 330
pF1KE0 LTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
:::::::::::::::::::::::::::::::::::
NP_848 LTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
310 320 330
>>NP_000665 (OMIM: 102775) adenosine receptor A1 [Homo s (326 aa)
initn: 316 init1: 147 opt: 317 Z-score: 321.3 bits: 67.8 E(85289): 3.7e-11
Smith-Waterman score: 347; 26.5% identity (57.5% similar) in 306 aa overlap (3-293:6-302)
10 20 30 40 50
pF1KE0 MESSFSFGVI-LAVLASLI-IATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIG
:.:. . : . :: .:. . :.:: :: . :. ..:: ..:::::. .:
NP_000 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDA-TFCFIVSLAVADVAVG
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 VAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLK
. . : : . . : : . : . .:.:... :. :::: .: :.::
NP_000 ALVIPLAI--LINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKM
60 70 80 90 100 110
120 130 140 150 160
pF1KE0 IMSGFVAGACIAGLWLVSYLIGFLPL----GIPMFQQT-AYKG-------QCSFFAVFHP
... :.. ::: :..:...:. :. .. ... : .: .: : :.
NP_000 VVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISM
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE0 HFVLTLSC-VGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFK
.... .. : .: .::.:..: :.. . .:. : :.. : . ...:
NP_000 EYMVYFNFFVWVLPPLLLMVLIY---LEVFYLIRKQLNKKVSASS---GDPQKYYGKELK
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE0 ALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYW
....... ::::: :. : . . . : :: .: .: ::: .::..::.
NP_000 IAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFR
240 250 260 270 280 290
290 300 310 320 330
pF1KE0 QKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
.. :. . ..
NP_000 IQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
300 310 320
>>NP_001041695 (OMIM: 102775) adenosine receptor A1 [Hom (326 aa)
initn: 316 init1: 147 opt: 317 Z-score: 321.3 bits: 67.8 E(85289): 3.7e-11
Smith-Waterman score: 347; 26.5% identity (57.5% similar) in 306 aa overlap (3-293:6-302)
10 20 30 40 50
pF1KE0 MESSFSFGVI-LAVLASLI-IATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIG
:.:. . : . :: .:. . :.:: :: . :. ..:: ..:::::. .:
NP_001 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDA-TFCFIVSLAVADVAVG
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 VAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLK
. . : : . . : : . : . .:.:... :. :::: .: :.::
NP_001 ALVIPLAI--LINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKM
60 70 80 90 100 110
120 130 140 150 160
pF1KE0 IMSGFVAGACIAGLWLVSYLIGFLPL----GIPMFQQT-AYKG-------QCSFFAVFHP
... :.. ::: :..:...:. :. .. ... : .: .: : :.
NP_001 VVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISM
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE0 HFVLTLSC-VGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFK
.... .. : .: .::.:..: :.. . .:. : :.. : . ...:
NP_001 EYMVYFNFFVWVLPPLLLMVLIY---LEVFYLIRKQLNKKVSASS---GDPQKYYGKELK
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE0 ALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYW
....... ::::: :. : . . . : :: .: .: ::: .::..::.
NP_001 IAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFR
240 250 260 270 280 290
290 300 310 320 330
pF1KE0 QKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
.. :. . ..
NP_001 IQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
300 310 320
>>NP_071640 (OMIM: 142703) histamine H2 receptor isoform (359 aa)
initn: 228 init1: 164 opt: 316 Z-score: 320.0 bits: 67.7 E(85289): 4.4e-11
Smith-Waterman score: 316; 25.2% identity (60.1% similar) in 286 aa overlap (9-287:23-296)
10 20 30 40
pF1KE0 MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLN
:.:::: . .: :..: .:: : .. ... :: ..
NP_071 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGL-NRRLRNLTNCFIVS
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 LAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLA
::..: :.:. . . . : . :..:.. .. . .::.:....:..::: :
NP_071 LAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCA
60 70 80 90 100 110
110 120 130 140 150
pF1KE0 IKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLP--LGIPMFQQTAYKG-----QCSFFA
. .:.:: ... .. .. .:..: ..:: :: ..:. :: .:. .
NP_071 VMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETS-KGNHTTSKCK--V
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE0 VFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPS
. . :. . : :. .:.. . : ..:.: .: ....: .. .. :
NP_071 QVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVAR---DQAKRINHISSWKAA-----TIR
180 190 200 210 220
220 230 240 250 260 270
pF1KE0 DFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIY
. :: :.....:.: . : :.. . . . . . ::: . :: .:: :::..:
NP_071 EHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILY
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE0 AYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
: ... :
NP_071 AALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGT
290 300 310 320 330 340
>>XP_006714928 (OMIM: 142703) PREDICTED: histamine H2 re (362 aa)
initn: 228 init1: 164 opt: 316 Z-score: 319.9 bits: 67.7 E(85289): 4.4e-11
Smith-Waterman score: 316; 25.2% identity (60.1% similar) in 286 aa overlap (9-287:23-296)
10 20 30 40
pF1KE0 MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLN
:.:::: . .: :..: .:: : .. ... :: ..
XP_006 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGL-NRRLRNLTNCFIVS
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 LAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLA
::..: :.:. . . . : . :..:.. .. . .::.:....:..::: :
XP_006 LAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCA
60 70 80 90 100 110
110 120 130 140 150
pF1KE0 IKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLP--LGIPMFQQTAYKG-----QCSFFA
. .:.:: ... .. .. .:..: ..:: :: ..:. :: .:. .
XP_006 VMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETS-KGNHTTSKCK--V
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE0 VFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPS
. . :. . : :. .:.. . : ..:.: .: ....: .. .. :
XP_006 QVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVAR---DQAKRINHISSWKAA-----TIR
180 190 200 210 220
220 230 240 250 260 270
pF1KE0 DFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIY
. :: :.....:.: . : :.. . . . . . ::: . :: .:: :::..:
XP_006 EHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILY
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE0 AYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
: ... :
XP_006 AALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGT
290 300 310 320 330 340
>>NP_001124527 (OMIM: 142703) histamine H2 receptor isof (397 aa)
initn: 228 init1: 164 opt: 316 Z-score: 319.6 bits: 67.7 E(85289): 4.6e-11
Smith-Waterman score: 316; 25.2% identity (60.1% similar) in 286 aa overlap (9-287:23-296)
10 20 30 40
pF1KE0 MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLN
:.:::: . .: :..: .:: : .. ... :: ..
NP_001 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGL-NRRLRNLTNCFIVS
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 LAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLA
::..: :.:. . . . : . :..:.. .. . .::.:....:..::: :
NP_001 LAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCA
60 70 80 90 100 110
110 120 130 140 150
pF1KE0 IKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLP--LGIPMFQQTAYKG-----QCSFFA
. .:.:: ... .. .. .:..: ..:: :: ..:. :: .:. .
NP_001 VMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETS-KGNHTTSKCK--V
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE0 VFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPS
. . :. . : :. .:.. . : ..:.: .: ....: .. .. :
NP_001 QVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVAR---DQAKRINHISSWKAA-----TIR
180 190 200 210 220
220 230 240 250 260 270
pF1KE0 DFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIY
. :: :.....:.: . : :.. . . . . . ::: . :: .:: :::..:
NP_001 EHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILY
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE0 AYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
: ... :
NP_001 AALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGT
290 300 310 320 330 340
>>XP_006714927 (OMIM: 142703) PREDICTED: histamine H2 re (422 aa)
initn: 228 init1: 164 opt: 316 Z-score: 319.4 bits: 67.8 E(85289): 4.7e-11
Smith-Waterman score: 316; 25.2% identity (60.1% similar) in 286 aa overlap (9-287:23-296)
10 20 30 40
pF1KE0 MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLN
:.:::: . .: :..: .:: : .. ... :: ..
XP_006 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGL-NRRLRNLTNCFIVS
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 LAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLA
::..: :.:. . . . : . :..:.. .. . .::.:....:..::: :
XP_006 LAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCA
60 70 80 90 100 110
110 120 130 140 150
pF1KE0 IKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLP--LGIPMFQQTAYKG-----QCSFFA
. .:.:: ... .. .. .:..: ..:: :: ..:. :: .:. .
XP_006 VMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETS-KGNHTTSKCK--V
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE0 VFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPS
. . :. . : :. .:.. . : ..:.: .: ....: .. .. :
XP_006 QVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVAR---DQAKRINHISSWKAA-----TIR
180 190 200 210 220
220 230 240 250 260 270
pF1KE0 DFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIY
. :: :.....:.: . : :.. . . . . . ::: . :: .:: :::..:
XP_006 EHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILY
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE0 AYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
: ... :
XP_006 AALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGT
290 300 310 320 330 340
>>XP_011532851 (OMIM: 142703) PREDICTED: histamine H2 re (422 aa)
initn: 228 init1: 164 opt: 316 Z-score: 319.4 bits: 67.8 E(85289): 4.7e-11
Smith-Waterman score: 316; 25.2% identity (60.1% similar) in 286 aa overlap (9-287:23-296)
10 20 30 40
pF1KE0 MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLN
:.:::: . .: :..: .:: : .. ... :: ..
XP_011 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGL-NRRLRNLTNCFIVS
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 LAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLA
::..: :.:. . . . : . :..:.. .. . .::.:....:..::: :
XP_011 LAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCA
60 70 80 90 100 110
110 120 130 140 150
pF1KE0 IKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLP--LGIPMFQQTAYKG-----QCSFFA
. .:.:: ... .. .. .:..: ..:: :: ..:. :: .:. .
XP_011 VMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETS-KGNHTTSKCK--V
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE0 VFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPS
. . :. . : :. .:.. . : ..:.: .: ....: .. .. :
XP_011 QVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVAR---DQAKRINHISSWKAA-----TIR
180 190 200 210 220
220 230 240 250 260 270
pF1KE0 DFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIY
. :: :.....:.: . : :.. . . . . . ::: . :: .:: :::..:
XP_011 EHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILY
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE0 AYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
: ... :
XP_011 AALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGT
290 300 310 320 330 340
>>XP_016864915 (OMIM: 142703) PREDICTED: histamine H2 re (422 aa)
initn: 228 init1: 164 opt: 316 Z-score: 319.4 bits: 67.8 E(85289): 4.7e-11
Smith-Waterman score: 316; 25.2% identity (60.1% similar) in 286 aa overlap (9-287:23-296)
10 20 30 40
pF1KE0 MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLN
:.:::: . .: :..: .:: : .. ... :: ..
XP_016 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGL-NRRLRNLTNCFIVS
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 LAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLA
::..: :.:. . . . : . :..:.. .. . .::.:....:..::: :
XP_016 LAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCA
60 70 80 90 100 110
110 120 130 140 150
pF1KE0 IKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLP--LGIPMFQQTAYKG-----QCSFFA
. .:.:: ... .. .. .:..: ..:: :: ..:. :: .:. .
XP_016 VMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETS-KGNHTTSKCK--V
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE0 VFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPS
. . :. . : :. .:.. . : ..:.: .: ....: .. .. :
XP_016 QVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVAR---DQAKRINHISSWKAA-----TIR
180 190 200 210 220
220 230 240 250 260 270
pF1KE0 DFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIY
. :: :.....:.: . : :.. . . . . . ::: . :: .:: :::..:
XP_016 EHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILY
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE0 AYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
: ... :
XP_016 AALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGT
290 300 310 320 330 340
>>XP_005265961 (OMIM: 142703) PREDICTED: histamine H2 re (422 aa)
initn: 228 init1: 164 opt: 316 Z-score: 319.4 bits: 67.8 E(85289): 4.7e-11
Smith-Waterman score: 316; 25.2% identity (60.1% similar) in 286 aa overlap (9-287:23-296)
10 20 30 40
pF1KE0 MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLN
:.:::: . .: :..: .:: : .. ... :: ..
XP_005 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGL-NRRLRNLTNCFIVS
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 LAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLA
::..: :.:. . . . : . :..:.. .. . .::.:....:..::: :
XP_005 LAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCA
60 70 80 90 100 110
110 120 130 140 150
pF1KE0 IKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLP--LGIPMFQQTAYKG-----QCSFFA
. .:.:: ... .. .. .:..: ..:: :: ..:. :: .:. .
XP_005 VMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETS-KGNHTTSKCK--V
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE0 VFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPS
. . :. . : :. .:.. . : ..:.: .: ....: .. .. :
XP_005 QVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVAR---DQAKRINHISSWKAA-----TIR
180 190 200 210 220
220 230 240 250 260 270
pF1KE0 DFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIY
. :: :.....:.: . : :.. . . . . . ::: . :: .:: :::..:
XP_005 EHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILY
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE0 AYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
: ... :
XP_005 AALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGT
290 300 310 320 330 340
335 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 03:16:39 2016 done: Sat Nov 5 03:16:40 2016
Total Scan time: 7.120 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]