Result of FASTA (omim) for
pFN21AE0757
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0757, 330 aa
1>>>pF1KE0757 330 - 330 aa - 330 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.3107+/-0.000361; mu= -6.0766+/- 0.023
mean_var=320.6572+/-66.399, 0's: 0 Z-trim(123.9): 86 B-trim: 33 in 1/55
Lambda= 0.071623
statistics sampled from 44475 (44572) to 44475 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.826), E-opt: 0.2 (0.523), width: 16
Scan time: 9.430
The best scores are: opt bits E(85289)
NP_003678 (OMIM: 166710,603422) PDZ and LIM domain ( 330) 2312 251.9 1.4e-66
NP_001124499 (OMIM: 166710,603422) PDZ and LIM dom ( 246) 1570 175.1 1.4e-43
XP_016865491 (OMIM: 166710,603422) PREDICTED: PDZ ( 252) 1561 174.1 2.7e-43
NP_066272 (OMIM: 605900) PDZ and LIM domain protei ( 329) 906 106.6 7.7e-23
NP_001244892 (OMIM: 605889) PDZ and LIM domain pro ( 197) 545 69.1 8.9e-12
NP_001244891 (OMIM: 605889) PDZ and LIM domain pro ( 276) 545 69.2 1.1e-11
NP_001107579 (OMIM: 605889) PDZ and LIM domain pro ( 316) 536 68.3 2.4e-11
NP_055291 (OMIM: 605889) PDZ and LIM domain protei ( 364) 536 68.4 2.7e-11
XP_011538632 (OMIM: 605900) PREDICTED: PDZ and LIM ( 226) 517 66.2 7.3e-11
NP_976227 (OMIM: 605903) PDZ and LIM domain protei ( 423) 428 57.3 6.9e-08
NP_001073584 (OMIM: 605906,609452) LIM domain-bind ( 330) 386 52.8 1.2e-06
XP_005269525 (OMIM: 605906,609452) PREDICTED: LIM ( 330) 386 52.8 1.2e-06
XP_016871097 (OMIM: 605906,609452) PREDICTED: LIM ( 330) 386 52.8 1.2e-06
XP_011537497 (OMIM: 605906,609452) PREDICTED: LIM ( 398) 383 52.6 1.6e-06
NP_001165082 (OMIM: 605906,609452) LIM domain-bind ( 398) 383 52.6 1.6e-06
XP_005269523 (OMIM: 605906,609452) PREDICTED: LIM ( 664) 386 53.1 1.9e-06
XP_005269521 (OMIM: 605906,609452) PREDICTED: LIM ( 727) 386 53.1 2.1e-06
NP_009009 (OMIM: 605906,609452) LIM domain-binding ( 727) 386 53.1 2.1e-06
XP_016871095 (OMIM: 605906,609452) PREDICTED: LIM ( 743) 386 53.1 2.1e-06
XP_011537490 (OMIM: 605906,609452) PREDICTED: LIM ( 743) 386 53.1 2.1e-06
NP_001165081 (OMIM: 605906,609452) LIM domain-bind ( 732) 383 52.8 2.6e-06
XP_011537489 (OMIM: 605906,609452) PREDICTED: LIM ( 748) 383 52.8 2.6e-06
XP_011537488 (OMIM: 605906,609452) PREDICTED: LIM ( 795) 383 52.9 2.7e-06
XP_011537487 (OMIM: 605906,609452) PREDICTED: LIM ( 811) 383 52.9 2.8e-06
XP_011537486 (OMIM: 605906,609452) PREDICTED: LIM ( 811) 383 52.9 2.8e-06
NP_006448 (OMIM: 605904) PDZ and LIM domain protei ( 596) 359 50.3 1.2e-05
XP_006714132 (OMIM: 605904) PREDICTED: PDZ and LIM ( 607) 358 50.2 1.3e-05
XP_005262752 (OMIM: 605904) PREDICTED: PDZ and LIM ( 728) 359 50.3 1.4e-05
NP_932159 (OMIM: 609722) PDZ and LIM domain protei ( 278) 348 48.8 1.5e-05
XP_006714129 (OMIM: 605904) PREDICTED: PDZ and LIM ( 739) 358 50.2 1.6e-05
NP_789847 (OMIM: 609722) PDZ and LIM domain protei ( 366) 349 49.1 1.8e-05
NP_998801 (OMIM: 605903) PDZ and LIM domain protei ( 222) 342 48.1 2e-05
XP_016863146 (OMIM: 605904) PREDICTED: PDZ and LIM ( 602) 351 49.4 2.2e-05
NP_067643 (OMIM: 609722) PDZ and LIM domain protei ( 602) 349 49.2 2.5e-05
XP_005262750 (OMIM: 605904) PREDICTED: PDZ and LIM ( 734) 351 49.5 2.6e-05
NP_005442 (OMIM: 605903) PDZ and LIM domain protei ( 457) 342 48.4 3.4e-05
XP_016863147 (OMIM: 605904) PREDICTED: PDZ and LIM ( 498) 336 47.8 5.6e-05
XP_006714131 (OMIM: 605904) PREDICTED: PDZ and LIM ( 630) 337 48.0 6.2e-05
XP_016871098 (OMIM: 605906,609452) PREDICTED: LIM ( 283) 326 46.6 7.6e-05
NP_001073585 (OMIM: 605906,609452) LIM domain-bind ( 283) 326 46.6 7.6e-05
NP_001011515 (OMIM: 605904) PDZ and LIM domain pro ( 234) 323 46.2 8.2e-05
XP_005262755 (OMIM: 605904) PREDICTED: PDZ and LIM ( 493) 327 46.9 0.00011
NP_001073583 (OMIM: 605906,609452) LIM domain-bind ( 617) 326 46.9 0.00013
XP_011537493 (OMIM: 605906,609452) PREDICTED: LIM ( 633) 326 46.9 0.00014
NP_001243356 (OMIM: 605904) PDZ and LIM domain pro ( 483) 323 46.5 0.00014
XP_011537492 (OMIM: 605906,609452) PREDICTED: LIM ( 680) 326 46.9 0.00014
XP_011537491 (OMIM: 605906,609452) PREDICTED: LIM ( 696) 326 46.9 0.00015
NP_001243355 (OMIM: 605904) PDZ and LIM domain pro ( 625) 323 46.6 0.00017
NP_001011516 (OMIM: 605904) PDZ and LIM domain pro ( 214) 307 44.5 0.00024
NP_001011513 (OMIM: 605904) PDZ and LIM domain pro ( 487) 313 45.4 0.00029
>>NP_003678 (OMIM: 166710,603422) PDZ and LIM domain pro (330 aa)
initn: 2312 init1: 2312 opt: 2312 Z-score: 1316.2 bits: 251.9 E(85289): 1.4e-66
Smith-Waterman score: 2312; 99.7% identity (99.7% similar) in 330 aa overlap (1-330:1-330)
10 20 30 40 50 60
pF1KE0 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KLGAPLSGLQGLPECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERL
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
NP_003 KLGAPLSGLQGLPECTRCGHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERL
250 260 270 280 290 300
310 320 330
pF1KE0 YCESHAKARVKPPEGYDVVAVYPNAKVELV
::::::::::::::::::::::::::::::
NP_003 YCESHAKARVKPPEGYDVVAVYPNAKVELV
310 320 330
>>NP_001124499 (OMIM: 166710,603422) PDZ and LIM domain (246 aa)
initn: 1570 init1: 1570 opt: 1570 Z-score: 903.5 bits: 175.1 E(85289): 1.4e-43
Smith-Waterman score: 1570; 95.0% identity (96.2% similar) in 240 aa overlap (1-240:1-240)
10 20 30 40 50 60
pF1KE0 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTAS
:::::::::::::::::::::::::::::::::::::::::::: . : . :.::
NP_001 DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGAPSSRHGTSSTIPSAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KLGAPLSGLQGLPECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERL
NP_001 CAVTAA
>>XP_016865491 (OMIM: 166710,603422) PREDICTED: PDZ and (252 aa)
initn: 1561 init1: 1561 opt: 1561 Z-score: 898.3 bits: 174.1 E(85289): 2.7e-43
Smith-Waterman score: 1615; 76.1% identity (76.1% similar) in 330 aa overlap (1-330:1-252)
10 20 30 40 50 60
pF1KE0 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM
:::::::::::::::::::::::::::::::
XP_016 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISR-----------------------------
10 20 30
70 80 90 100 110 120
pF1KE0 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS
:::::::::::
XP_016 -------------------------------------------------DGSPTTSRRPS
40
130 140 150 160 170 180
pF1KE0 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE0 DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTAS
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE0 KLGAPLSGLQGLPECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERL
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_016 KLGAPLSGLQGLPECTRCGHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERL
170 180 190 200 210 220
310 320 330
pF1KE0 YCESHAKARVKPPEGYDVVAVYPNAKVELV
::::::::::::::::::::::::::::::
XP_016 YCESHAKARVKPPEGYDVVAVYPNAKVELV
230 240 250
>>NP_066272 (OMIM: 605900) PDZ and LIM domain protein 1 (329 aa)
initn: 924 init1: 474 opt: 906 Z-score: 531.0 bits: 106.6 E(85289): 7.7e-23
Smith-Waterman score: 906; 44.6% identity (67.5% similar) in 332 aa overlap (3-323:4-328)
10 20 30 40 50
pF1KE0 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTEL
... :.::.:::::::::.:: ::.:::: ::::::: :: ::.: ::.::.:
NP_066 MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 MTHLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQD----GSP-
::::::::::::: :.:::.:.: : . : : . ...: . ..... : :. ::
NP_066 MTHLEAQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAH
70 80 90 100 110 120
120 130 140 150 160
pF1KE0 TTSRRPSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSS-----EATLPAQMSTLHVSPPP
. : : .. . . . :..: . .: :. :. :. . :
NP_066 NRSAMPFTASPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLD
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 SADPARGLPRSRDCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPG
:.: .: .: ::::.::.: : . :::: :: :: .::. : ::
NP_066 HAQPPSSL------VIDKESEVYKMLQEKQE-LNEPPKQSTSFLVLQEILESEEKGDPNK
190 200 210 220 230
230 240 250 260 270 280
pF1KE0 PGGPRNLKPTASKLGAPLSGLQGLPECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNL
:.: :..: ..:..: ... : :: : .: ::::..:: ::. ::::..:.::: ::
NP_066 PSGFRSVKAPVTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNL
240 250 260 270 280 290
290 300 310 320 330
pF1KE0 KQRGYFFLDERLYCESHAKARVKPPEGYDVVAVYPNAKVELV
::.:.::.....:::.::. :: :::::.::.:.:
NP_066 KQKGHFFVEDQIYCEKHARERVTPPEGYEVVTVFPK
300 310 320
>>NP_001244892 (OMIM: 605889) PDZ and LIM domain protein (197 aa)
initn: 606 init1: 363 opt: 545 Z-score: 332.4 bits: 69.1 E(85289): 8.9e-12
Smith-Waterman score: 550; 43.6% identity (67.6% similar) in 204 aa overlap (123-325:9-197)
100 110 120 130 140 150
pF1KE0 DDSKAQAHRIHIDPEIQDGSPTTSRRPSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSE
: .: : : : ..:: . . ..:.
NP_001 MPQTVILPGPAPWGFRLSGGIDFNQP--LVITRDGNYF
10 20 30
160 170 180 190 200 210
pF1KE0 ATLPAQMSTLHVSPPPSADPARGLPRSRDCRVDLGSEVYRMLREP-AEPVAAEPKQSGSF
: : :..:. ..: : :::::.. ::. .:.:::::
NP_001 EHKHNIRPKPFVIPGRSSEPTASVPPESD--------VYRMLHDNRNEPT--QPRQSGSF
40 50 60 70 80
220 230 240 250 260 270
pF1KE0 RYLQGMLEAGEGGDWPGPGGPRNLKPTASKLGAPLSGLQGLPECTRCCHGIVGTIVKARD
: ::::.. .:.: :.: :... ..:. . .: : .: : .: ::::..:::::
NP_001 RVLQGMVD--DGSD-DRPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARD
90 100 110 120 130 140
280 290 300 310 320 330
pF1KE0 KLYHPECFMCSDCGLNLKQRGYFFLDERLYCESHAKARVKPPEGYDVVAVYPNAKVELV
: :::::.:.::.:::::.::::.. .::::.::.::.:::::::.:..::.:
NP_001 KYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTLYPKA
150 160 170 180 190
>>NP_001244891 (OMIM: 605889) PDZ and LIM domain protein (276 aa)
initn: 827 init1: 363 opt: 545 Z-score: 330.4 bits: 69.2 E(85289): 1.1e-11
Smith-Waterman score: 869; 45.0% identity (66.7% similar) in 327 aa overlap (1-325:1-276)
10 20 30 40 50 60
pF1KE0 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM
::..: : ::.:::::: :: ::. ::.:.:. ::::: : :::::.: ::.: .:: :
NP_001 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 THLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQDGSPTTSRRP
:: .::.:::. .: :...: : . : :.. .:.::. .:... : :::. ..
NP_001 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKH-
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 SGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRS
. ::. :. : : ::: : .: :: .:
NP_001 --------NIRPK---PFVIPGR-------SSEPT---------ASVPPESD--------
120 130 140
180 190 200 210 220 230
pF1KE0 RDCRVDLGSEVYRMLREP-AEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPT
:::::.. ::. .:.:::::: ::::.. .:.: :.: :...
NP_001 ----------VYRMLHDNRNEPT--QPRQSGSFRVLQGMVD--DGSD-DRPAGTRSVRAP
150 160 170 180
240 250 260 270 280 290
pF1KE0 ASKLGAPLSGLQGLPECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDE
..:. . .: : .: : .: ::::..:::::: :::::.:.::.:::::.::::..
NP_001 VTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEG
190 200 210 220 230 240
300 310 320 330
pF1KE0 RLYCESHAKARVKPPEGYDVVAVYPNAKVELV
.::::.::.::.:::::::.:..::.:
NP_001 ELYCETHARARTKPPEGYDTVTLYPKA
250 260 270
>>NP_001107579 (OMIM: 605889) PDZ and LIM domain protein (316 aa)
initn: 796 init1: 363 opt: 536 Z-score: 324.6 bits: 68.3 E(85289): 2.4e-11
Smith-Waterman score: 923; 44.3% identity (71.7% similar) in 332 aa overlap (1-325:1-316)
10 20 30 40 50 60
pF1KE0 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM
::..: : ::.:::::: :: ::. ::.:.:. ::::: : :::::.: ::.: .:: :
NP_001 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 THLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQDGSPTTS---
:: .::.:::. .: :...: : . : :.. .:.::. .:... : :. .: .
NP_001 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHN
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 RR--PSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPAR
:: : .... .: : ... :..: . . ... . .: .:. : . :. .:.
NP_001 RRAQPFVAAANIDDKRQVVSASYNSP--IGLYSTSNIQDALHGQLRGL-IPSSPQNEPTA
130 140 150 160 170
180 190 200 210 220 230
pF1KE0 GLPRSRDCRVDLGSEVYRMLREP-AEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPR
..: : :::::.. :: ..:.:::::: ::::.. .:.: :.: :
NP_001 SVPPESD--------VYRMLHDNRNEP--TQPRQSGSFRVLQGMVD--DGSD-DRPAGTR
180 190 200 210 220
240 250 260 270 280 290
pF1KE0 NLKPTASKLGAPLSGLQGLPECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGY
... ..:. . .: : .: : .: ::::..:::::: :::::.:.::.:::::.::
NP_001 SVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGY
230 240 250 260 270 280
300 310 320 330
pF1KE0 FFLDERLYCESHAKARVKPPEGYDVVAVYPNAKVELV
::.. .::::.::.::.:::::::.:..::.:
NP_001 FFIEGELYCETHARARTKPPEGYDTVTLYPKA
290 300 310
>>NP_055291 (OMIM: 605889) PDZ and LIM domain protein 3 (364 aa)
initn: 849 init1: 363 opt: 536 Z-score: 323.8 bits: 68.4 E(85289): 2.7e-11
Smith-Waterman score: 842; 42.3% identity (62.9% similar) in 364 aa overlap (9-325:9-364)
10 20 30 40 50 60
pF1KE0 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM
::.:::::: :: ::. ::.:.:. ::::: : :::::.: ::.: .:: :
NP_055 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 THLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQDGS-------
:: .::.:::. .: :...: : . : :.. .:.::. .:... : :::.
NP_055 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHN
70 80 90 100 110 120
120 130 140
pF1KE0 --------PTTSR---RPSGTGTGPEDGRPSLGSPYGQ--P----------PRFPVPHN-
: : ::: : . :: : . : : .:. .
NP_055 IRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEMEL
130 140 150 160 170 180
150 160 170 180 190
pF1KE0 -G----SSEATLPAQ-------MSTLH--VSPPPSADPARGLPRSRDCRVDLGSEVYRML
: .. . : : : ::. :: . : . : . : :.:::::
NP_055 PGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSEPTAS---VPPESDVYRML
190 200 210 220 230
200 210 220 230 240 250
pF1KE0 REP-AEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTASKLGAPLSGLQGLP
.. :: ..:.:::::: ::::.. .:.: :.: :... ..:. . .: : .:
NP_055 HDNRNEP--TQPRQSGSFRVLQGMVD--DGSD-DRPAGTRSVRAPVTKVHGGSGGAQRMP
240 250 260 270 280 290
260 270 280 290 300 310
pF1KE0 ECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERLYCESHAKARVKPP
: .: ::::..:::::: :::::.:.::.:::::.::::.. .::::.::.::.:::
NP_055 LCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPP
300 310 320 330 340 350
320 330
pF1KE0 EGYDVVAVYPNAKVELV
::::.:..::.:
NP_055 EGYDTVTLYPKA
360
>>XP_011538632 (OMIM: 605900) PREDICTED: PDZ and LIM dom (226 aa)
initn: 537 init1: 474 opt: 517 Z-score: 316.0 bits: 66.2 E(85289): 7.3e-11
Smith-Waterman score: 517; 44.9% identity (68.8% similar) in 176 aa overlap (148-323:57-225)
120 130 140 150 160 170
pF1KE0 RPSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLP
:.. :. :. . : :.: .:
XP_011 SPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLDHAQPPSSLV
30 40 50 60 70 80
180 190 200 210 220 230
pF1KE0 RSRDCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKP
.: ::::.::.: : . :::: :: :: .::. : :: :.: :..:
XP_011 ------IDKESEVYKMLQEKQE-LNEPPKQSTSFLVLQEILESEEKGDPNKPSGFRSVKA
90 100 110 120 130
240 250 260 270 280 290
pF1KE0 TASKLGAPLSGLQGLPECTRCCHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLD
..:..: ... : :: : .: ::::..:: ::. ::::..:.::: ::::.:.::..
XP_011 PVTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGHFFVE
140 150 160 170 180 190
300 310 320 330
pF1KE0 ERLYCESHAKARVKPPEGYDVVAVYPNAKVELV
...:::.::. :: :::::.::.:.:
XP_011 DQIYCEKHARERVTPPEGYEVVTVFPK
200 210 220
>>NP_976227 (OMIM: 605903) PDZ and LIM domain protein 7 (423 aa)
initn: 481 init1: 289 opt: 428 Z-score: 262.6 bits: 57.3 E(85289): 6.9e-08
Smith-Waterman score: 455; 33.0% identity (52.4% similar) in 336 aa overlap (5-312:6-305)
10 20 30 40 50
pF1KE0 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTEL
:.:.::.:::::: ::.::..::.:::. :.::: :.. :: . .:.::..
NP_976 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 MTHLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQA-HRIHIDPEIQDGSP-----
.::.::::.:..: ..:.:..:: . : .:.:. . . : . :.:
NP_976 LTHIEAQNKIRACGERLSLGLSRAQ----PVQSKPQKVQTPDKQPLRPLVPDASKQRLME
70 80 90 100 110
120 130 140 150
pF1KE0 -TTSRRPS-GTG-----------TGPE---DGRPSLGSPYGQPPRF--PVPHNGSSEATL
: . :: ::: :: : : . .: :: :.: ... .
NP_976 NTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEEHLKKSSQVPRTEAPAPASSTPQEPW
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE0 PAQMSTLHVSPPPSA-DPA---RGLPRSRDCRVDLGSEVYRMLREPAEPVAAEPKQSGSF
:. . .: :: : ::: : : : : : .:: :. : :: .
NP_976 PGPTAPSPTSRPPWAVDPAFAERYAP-------DKTSTVLTRHSQPATPT---PLQSRT-
180 190 200 210 220
220 230 240 250 260 270
pF1KE0 RYLQGMLEAGEGGDWPGPGGPRNLKPTASKLGAPLSGLQGLPECTRCCHGIVGTIVKARD
....:. :: :: :: : : : : .: . : : . :
NP_976 ----SIVQAAAGG-VPG-GGSNNGKT---------------PVCHQCHKVIRGRYLVALG
230 240 250 260
280 290 300 310 320 330
pF1KE0 KLYHPECFMCSDCGLNLKQRGYFFLDERLYCESHAKARVKPPEGYDVVAVYPNAKVELV
. :::: :.::.:: :.. :.: ..: .: :
NP_976 HAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKM
270 280 290 300 310 320
NP_976 TWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALG
330 340 350 360 370 380
330 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 03:04:18 2016 done: Sat Nov 5 03:04:19 2016
Total Scan time: 9.430 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]