Result of FASTA (omim) for
pFN21AE0742
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0742, 424 aa
1>>>pF1KE0742 424 - 424 aa - 424 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.3349+/-0.000461; mu= 5.4541+/- 0.028
mean_var=498.5456+/-112.314, 0's: 0 Z-trim(119.6): 1841 B-trim: 0 in 0/58
Lambda= 0.057441
statistics sampled from 31402 (33876) to 31402 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.733), E-opt: 0.2 (0.397), width: 16
Scan time: 9.940
The best scores are: opt bits E(85289)
NP_006733 (OMIM: 177015) serine/threonine-protein ( 424) 2807 247.6 4.5e-65
XP_006717546 (OMIM: 607957) PREDICTED: calcium/cal ( 355) 940 92.8 1.5e-18
NP_065130 (OMIM: 607957) calcium/calmodulin-depend ( 357) 940 92.8 1.5e-18
XP_006717545 (OMIM: 607957) PREDICTED: calcium/cal ( 362) 940 92.8 1.6e-18
NP_705718 (OMIM: 607957) calcium/calmodulin-depend ( 385) 940 92.8 1.6e-18
NP_003647 (OMIM: 604998) calcium/calmodulin-depend ( 370) 925 91.5 3.7e-18
XP_005265573 (OMIM: 604998) PREDICTED: calcium/cal ( 413) 925 91.6 3.9e-18
XP_006717544 (OMIM: 607957) PREDICTED: calcium/cal ( 366) 921 91.2 4.6e-18
XP_011517893 (OMIM: 607957) PREDICTED: calcium/cal ( 372) 921 91.2 4.7e-18
XP_016884766 (OMIM: 300680) PREDICTED: calcium/cal ( 426) 866 86.8 1.2e-16
NP_001034671 (OMIM: 300680) calcium/calmodulin-dep ( 426) 866 86.8 1.2e-16
XP_016884768 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 861 86.2 1.4e-16
XP_005274708 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 861 86.2 1.4e-16
XP_011529414 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 861 86.2 1.4e-16
XP_006724872 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 861 86.2 1.4e-16
XP_011529409 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 861 86.2 1.4e-16
XP_011529413 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 861 86.2 1.4e-16
XP_016884767 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 861 86.2 1.4e-16
XP_011529412 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 861 86.2 1.4e-16
NP_001129212 (OMIM: 300680) calcium/calmodulin-dep ( 360) 861 86.2 1.4e-16
XP_011529410 (OMIM: 300680) PREDICTED: calcium/cal ( 361) 861 86.2 1.4e-16
XP_011517895 (OMIM: 607957) PREDICTED: calcium/cal ( 311) 821 82.8 1.3e-15
XP_011517894 (OMIM: 607957) PREDICTED: calcium/cal ( 315) 821 82.8 1.4e-15
XP_016862843 (OMIM: 604998) PREDICTED: calcium/cal ( 326) 821 82.8 1.4e-15
XP_005265574 (OMIM: 604998) PREDICTED: calcium/cal ( 369) 821 82.9 1.5e-15
XP_016857355 (OMIM: 614994) PREDICTED: calcium/cal ( 476) 821 83.1 1.6e-15
NP_065172 (OMIM: 614994) calcium/calmodulin-depend ( 476) 821 83.1 1.6e-15
NP_001735 (OMIM: 114080) calcium/calmodulin-depend ( 473) 801 81.5 5.2e-15
NP_001310303 (OMIM: 114080) calcium/calmodulin-dep ( 473) 801 81.5 5.2e-15
NP_001310304 (OMIM: 114080) calcium/calmodulin-dep ( 473) 801 81.5 5.2e-15
XP_016871928 (OMIM: 607957) PREDICTED: calcium/cal ( 260) 754 77.1 5.8e-14
XP_011517897 (OMIM: 607957) PREDICTED: calcium/cal ( 288) 754 77.2 6.1e-14
XP_016871927 (OMIM: 607957) PREDICTED: calcium/cal ( 288) 754 77.2 6.1e-14
XP_016864166 (OMIM: 607708) PREDICTED: calcium/cal ( 491) 745 76.8 1.3e-13
NP_001308506 (OMIM: 607708) calcium/calmodulin-dep ( 491) 745 76.8 1.3e-13
XP_016864163 (OMIM: 607708) PREDICTED: calcium/cal ( 511) 745 76.9 1.3e-13
XP_016864162 (OMIM: 607708) PREDICTED: calcium/cal ( 512) 745 76.9 1.3e-13
XP_005263311 (OMIM: 607708) PREDICTED: calcium/cal ( 532) 745 76.9 1.4e-13
XP_006714393 (OMIM: 607708) PREDICTED: calcium/cal ( 478) 744 76.7 1.4e-13
NP_001308512 (OMIM: 607708) calcium/calmodulin-dep ( 492) 744 76.8 1.4e-13
NP_001308504 (OMIM: 607708) calcium/calmodulin-dep ( 492) 744 76.8 1.4e-13
NP_001308497 (OMIM: 607708) calcium/calmodulin-dep ( 503) 744 76.8 1.4e-13
XP_011530597 (OMIM: 607708) PREDICTED: calcium/cal ( 510) 744 76.8 1.4e-13
NP_001308501 (OMIM: 607708) calcium/calmodulin-dep ( 512) 744 76.8 1.4e-13
NP_001308496 (OMIM: 607708) calcium/calmodulin-dep ( 512) 744 76.8 1.4e-13
XP_016864161 (OMIM: 607708) PREDICTED: calcium/cal ( 513) 744 76.8 1.4e-13
NP_001308500 (OMIM: 607708) calcium/calmodulin-dep ( 533) 744 76.8 1.4e-13
NP_001305866 (OMIM: 601685) ribosomal protein S6 k ( 635) 744 76.9 1.6e-13
NP_001305867 (OMIM: 601685) ribosomal protein S6 k ( 644) 744 77.0 1.6e-13
NP_066958 (OMIM: 601685) ribosomal protein S6 kina ( 733) 744 77.1 1.7e-13
>>NP_006733 (OMIM: 177015) serine/threonine-protein kina (424 aa)
initn: 2807 init1: 2807 opt: 2807 Z-score: 1289.3 bits: 247.6 E(85289): 4.5e-65
Smith-Waterman score: 2807; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424)
10 20 30 40 50 60
pF1KE0 MGCGTSKVLPEPPKDVQLDLVKKVEPFSGTKSDVYKHFITEVDSVGPVKAGFPAASQYAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MGCGTSKVLPEPPKDVQLDLVKKVEPFSGTKSDVYKHFITEVDSVGPVKAGFPAASQYAH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PCPGPPTAGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PCPGPPTAGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRAT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 RQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGEL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 FDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 GLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 NRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 SSSMKNLHRSISQNLLKRASSRCQSTKSAQSTRSSRSTRSNKSRRVRERELRELNLRYQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SSSMKNLHRSISQNLLKRASSRCQSTKSAQSTRSSRSTRSNKSRRVRERELRELNLRYQQ
370 380 390 400 410 420
pF1KE0 QYNG
::::
NP_006 QYNG
>>XP_006717546 (OMIM: 607957) PREDICTED: calcium/calmodu (355 aa)
initn: 867 init1: 437 opt: 940 Z-score: 453.8 bits: 92.8 E(85289): 1.5e-18
Smith-Waterman score: 940; 48.8% identity (79.4% similar) in 281 aa overlap (98-377:23-299)
70 80 90 100 110 120
pF1KE0 AGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIK
...: .: :.::.:: .:..:: . .:.:
XP_006 MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVK
10 20 30 40 50
130 140 150 160 170 180
pF1KE0 MIETKYREGREVC-ESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIA
: : .:.: :.:. :::...: ::. : ...:. ...:.::.:..::::::::.
XP_006 CIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVE
60 70 80 90 100 110
190 200 210 220 230 240
pF1KE0 KGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASAR
:: .::.::. ....:::.: ::: .::.:::::::::::: .:::.:.::::.. .
XP_006 KGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKME
120 130 140 150 160 170
250 260 270 280 290 300
pF1KE0 KKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLY
::: .:.:.:::: :.:::::..:::...:: :..:::::::: : :: :.: ..:.
XP_006 GKGD--VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLF
180 190 200 210 220 230
310 320 330 340 350 360
pF1KE0 RQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKN
.:::...: ... : ..:. ::::: :. ::. :.: :: ::::... .: . ::
XP_006 EQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALN--KN
240 250 260 270 280
370 380 390 400 410 420
pF1KE0 LHRSISQNLLKRASSRCQSTKSAQSTRSSRSTRSNKSRRVRERELRELNLRYQQQYNG
.:.:.: .. :
XP_006 IHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQKDCA
290 300 310 320 330 340
>>NP_065130 (OMIM: 607957) calcium/calmodulin-dependent (357 aa)
initn: 867 init1: 437 opt: 940 Z-score: 453.8 bits: 92.8 E(85289): 1.5e-18
Smith-Waterman score: 940; 48.8% identity (79.4% similar) in 281 aa overlap (98-377:23-299)
70 80 90 100 110 120
pF1KE0 AGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIK
...: .: :.::.:: .:..:: . .:.:
NP_065 MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVK
10 20 30 40 50
130 140 150 160 170 180
pF1KE0 MIETKYREGREVC-ESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIA
: : .:.: :.:. :::...: ::. : ...:. ...:.::.:..::::::::.
NP_065 CIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVE
60 70 80 90 100 110
190 200 210 220 230 240
pF1KE0 KGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASAR
:: .::.::. ....:::.: ::: .::.:::::::::::: .:::.:.::::.. .
NP_065 KGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKME
120 130 140 150 160 170
250 260 270 280 290 300
pF1KE0 KKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLY
::: .:.:.:::: :.:::::..:::...:: :..:::::::: : :: :.: ..:.
NP_065 GKGD--VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLF
180 190 200 210 220 230
310 320 330 340 350 360
pF1KE0 RQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKN
.:::...: ... : ..:. ::::: :. ::. :.: :: ::::... .: . ::
NP_065 EQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALN--KN
240 250 260 270 280
370 380 390 400 410 420
pF1KE0 LHRSISQNLLKRASSRCQSTKSAQSTRSSRSTRSNKSRRVRERELRELNLRYQQQYNG
.:.:.: .. :
NP_065 IHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQKDCA
290 300 310 320 330 340
>>XP_006717545 (OMIM: 607957) PREDICTED: calcium/calmodu (362 aa)
initn: 902 init1: 437 opt: 940 Z-score: 453.8 bits: 92.8 E(85289): 1.6e-18
Smith-Waterman score: 940; 48.8% identity (79.4% similar) in 281 aa overlap (98-377:23-299)
70 80 90 100 110 120
pF1KE0 AGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIK
...: .: :.::.:: .:..:: . .:.:
XP_006 MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVK
10 20 30 40 50
130 140 150 160 170 180
pF1KE0 MIETKYREGREVC-ESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIA
: : .:.: :.:. :::...: ::. : ...:. ...:.::.:..::::::::.
XP_006 CIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVE
60 70 80 90 100 110
190 200 210 220 230 240
pF1KE0 KGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASAR
:: .::.::. ....:::.: ::: .::.:::::::::::: .:::.:.::::.. .
XP_006 KGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKME
120 130 140 150 160 170
250 260 270 280 290 300
pF1KE0 KKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLY
::: .:.:.:::: :.:::::..:::...:: :..:::::::: : :: :.: ..:.
XP_006 GKGD--VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLF
180 190 200 210 220 230
310 320 330 340 350 360
pF1KE0 RQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKN
.:::...: ... : ..:. ::::: :. ::. :.: :: ::::... .: . ::
XP_006 EQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALN--KN
240 250 260 270 280
370 380 390 400 410 420
pF1KE0 LHRSISQNLLKRASSRCQSTKSAQSTRSSRSTRSNKSRRVRERELRELNLRYQQQYNG
.:.:.: .. :
XP_006 IHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNVWHLPRSVVSFLLRRG
290 300 310 320 330 340
>>NP_705718 (OMIM: 607957) calcium/calmodulin-dependent (385 aa)
initn: 888 init1: 437 opt: 940 Z-score: 453.5 bits: 92.8 E(85289): 1.6e-18
Smith-Waterman score: 940; 48.8% identity (79.4% similar) in 281 aa overlap (98-377:23-299)
70 80 90 100 110 120
pF1KE0 AGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIK
...: .: :.::.:: .:..:: . .:.:
NP_705 MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVK
10 20 30 40 50
130 140 150 160 170 180
pF1KE0 MIETKYREGREVC-ESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIA
: : .:.: :.:. :::...: ::. : ...:. ...:.::.:..::::::::.
NP_705 CIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVE
60 70 80 90 100 110
190 200 210 220 230 240
pF1KE0 KGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASAR
:: .::.::. ....:::.: ::: .::.:::::::::::: .:::.:.::::.. .
NP_705 KGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKME
120 130 140 150 160 170
250 260 270 280 290 300
pF1KE0 KKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLY
::: .:.:.:::: :.:::::..:::...:: :..:::::::: : :: :.: ..:.
NP_705 GKGD--VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLF
180 190 200 210 220 230
310 320 330 340 350 360
pF1KE0 RQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKN
.:::...: ... : ..:. ::::: :. ::. :.: :: ::::... .: . ::
NP_705 EQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALN--KN
240 250 260 270 280
370 380 390 400 410 420
pF1KE0 LHRSISQNLLKRASSRCQSTKSAQSTRSSRSTRSNKSRRVRERELRELNLRYQQQYNG
.:.:.: .. :
NP_705 IHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQKDCL
290 300 310 320 330 340
>>NP_003647 (OMIM: 604998) calcium/calmodulin-dependent (370 aa)
initn: 886 init1: 426 opt: 925 Z-score: 447.0 bits: 91.5 E(85289): 3.7e-18
Smith-Waterman score: 925; 45.9% identity (77.2% similar) in 303 aa overlap (98-399:20-317)
70 80 90 100 110 120
pF1KE0 AGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIK
::.. ..: :.::.:. .: . :.. :::
NP_003 MLGAVEGPRWKQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIK
10 20 30 40
130 140 150 160 170 180
pF1KE0 MIETKYREGRE-VCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIA
: . ::.: :.:. ::....: ::. : ...:. ..:..:.:..::::::::.
NP_003 CIAKEALEGKEGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVE
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE0 KGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASAR
:: .:::::.:.. .:::.:.::: :::.:::::::::::: ::::.:.::::.. .
NP_003 KGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKME
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE0 KKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLY
:. ...:.:::: :.:::::..:::...:: :..:::::::: : :: :.: ..:.
NP_003 DPGS--VLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLF
170 180 190 200 210 220
310 320 330 340 350 360
pF1KE0 RQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKN
.:::...: ... : ..:. ::::: .:. :: :.: :::.:::... .: . ::
NP_003 EQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALD--KN
230 240 250 260 270 280
370 380 390 400 410 420
pF1KE0 LHRSISQNLLKRASSRCQSTKSAQSTRSSRSTRSNKSRRVRERELRELNLRYQQQYNG
.:.:.:... :. .. . .. ..: : :
NP_003 IHQSVSEQI-KKNFAKSKWKQAFNATAVVRHMRKLQLGTSQEGQGQTASHGELLTPVAGG
290 300 310 320 330 340
NP_003 PAAGCCCRDCCVEPGTELSPTLPHQL
350 360 370
>>XP_005265573 (OMIM: 604998) PREDICTED: calcium/calmodu (413 aa)
initn: 886 init1: 426 opt: 925 Z-score: 446.5 bits: 91.6 E(85289): 3.9e-18
Smith-Waterman score: 925; 45.9% identity (77.2% similar) in 303 aa overlap (98-399:20-317)
70 80 90 100 110 120
pF1KE0 AGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIK
::.. ..: :.::.:. .: . :.. :::
XP_005 MLGAVEGPRWKQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIK
10 20 30 40
130 140 150 160 170 180
pF1KE0 MIETKYREGRE-VCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIA
: . ::.: :.:. ::....: ::. : ...:. ..:..:.:..::::::::.
XP_005 CIAKEALEGKEGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVE
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE0 KGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASAR
:: .:::::.:.. .:::.:.::: :::.:::::::::::: ::::.:.::::.. .
XP_005 KGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKME
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE0 KKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLY
:. ...:.:::: :.:::::..:::...:: :..:::::::: : :: :.: ..:.
XP_005 DPGS--VLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLF
170 180 190 200 210 220
310 320 330 340 350 360
pF1KE0 RQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKN
.:::...: ... : ..:. ::::: .:. :: :.: :::.:::... .: . ::
XP_005 EQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALD--KN
230 240 250 260 270 280
370 380 390 400 410 420
pF1KE0 LHRSISQNLLKRASSRCQSTKSAQSTRSSRSTRSNKSRRVRERELRELNLRYQQQYNG
.:.:.:... :. .. . .. ..: : :
XP_005 IHQSVSEQI-KKNFAKSKWKQAFNATAVVRHMRKLQLGTSQEGQGQTASHGELLTPVAGG
290 300 310 320 330 340
XP_005 EERALQKGMGGPQRCTRAGVEGLPLRPPLFCLPMQGRQLAVAVETAAWSRAQNCPPHCPT
350 360 370 380 390 400
>>XP_006717544 (OMIM: 607957) PREDICTED: calcium/calmodu (366 aa)
initn: 869 init1: 437 opt: 921 Z-score: 445.2 bits: 91.2 E(85289): 4.6e-18
Smith-Waterman score: 921; 49.6% identity (79.8% similar) in 272 aa overlap (107-377:13-280)
80 90 100 110 120 130
pF1KE0 PPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREG
:.::.:: .:..:: . .:.: : : .:
XP_006 MNVDLLSCALWSGAFSEVVLAEEKATGKLFAVKCIPKKALKG
10 20 30 40
140 150 160 170 180 190
pF1KE0 REVC-ESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDA
.: :.:. :::...: ::. : ...:. ...:.::.:..::::::::. :: .::.::
XP_006 KESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDA
50 60 70 80 90 100
200 210 220 230 240 250
pF1KE0 TRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMK
. ....:::.: ::: .::.:::::::::::: .:::.:.::::.. . ::: .:.
XP_006 STLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGD--VMS
110 120 130 140 150 160
260 270 280 290 300 310
pF1KE0 TTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYS
:.:::: :.:::::..:::...:: :..:::::::: : :: :.: ..:..:::...:
XP_006 TACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYE
170 180 190 200 210 220
320 330 340 350 360 370
pF1KE0 YSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNL
... : ..:. ::::: :. ::. :.: :: ::::... .: . ::.:.:.: ..
XP_006 FDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALN--KNIHESVSAQI
230 240 250 260 270
380 390 400 410 420
pF1KE0 LKRASSRCQSTKSAQSTRSSRSTRSNKSRRVRERELRELNLRYQQQYNG
:
XP_006 RKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQKDCLAPSTLCSFI
280 290 300 310 320 330
>>XP_011517893 (OMIM: 607957) PREDICTED: calcium/calmodu (372 aa)
initn: 869 init1: 437 opt: 921 Z-score: 445.1 bits: 91.2 E(85289): 4.7e-18
Smith-Waterman score: 921; 49.6% identity (79.8% similar) in 272 aa overlap (107-377:19-286)
80 90 100 110 120 130
pF1KE0 PPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREG
:.::.:: .:..:: . .:.: : : .:
XP_011 METPPYSMEGPSCPICPSGAFSEVVLAEEKATGKLFAVKCIPKKALKG
10 20 30 40
140 150 160 170 180 190
pF1KE0 REVC-ESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDA
.: :.:. :::...: ::. : ...:. ...:.::.:..::::::::. :: .::.::
XP_011 KESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDA
50 60 70 80 90 100
200 210 220 230 240 250
pF1KE0 TRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMK
. ....:::.: ::: .::.:::::::::::: .:::.:.::::.. . ::: .:.
XP_011 STLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGD--VMS
110 120 130 140 150 160
260 270 280 290 300 310
pF1KE0 TTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYS
:.:::: :.:::::..:::...:: :..:::::::: : :: :.: ..:..:::...:
XP_011 TACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYE
170 180 190 200 210 220
320 330 340 350 360 370
pF1KE0 YSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNL
... : ..:. ::::: :. ::. :.: :: ::::... .: . ::.:.:.: ..
XP_011 FDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALN--KNIHESVSAQI
230 240 250 260 270 280
380 390 400 410 420
pF1KE0 LKRASSRCQSTKSAQSTRSSRSTRSNKSRRVRERELRELNLRYQQQYNG
:
XP_011 RKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQKDCLAPSTLCSFI
290 300 310 320 330 340
>>XP_016884766 (OMIM: 300680) PREDICTED: calcium/calmodu (426 aa)
initn: 766 init1: 413 opt: 866 Z-score: 420.0 bits: 86.8 E(85289): 1.2e-16
Smith-Waterman score: 866; 42.4% identity (69.1% similar) in 356 aa overlap (46-399:50-394)
20 30 40 50 60 70
pF1KE0 VQLDLVKKVEPFSGTKSDVYKHFITEVDSVGPVKAGFPAASQYAHPCPGPPTAGHTEPPS
:: :: : . :. : .: . ::
XP_016 GRDWKAESLADLWPKSSPGDSHRWCKGPGAGP--AG-PQLREAARASSG--LGGGGRHPS
20 30 40 50 60 70
80 90 100 110 120 130
pF1KE0 EPPRRA-RVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYR
. : : . : ... :.:. .: :.::.:: ...:.. . :.: : :
XP_016 RIPAIALQDMLLLKKHTEDISSVYEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKAL
80 90 100 110 120 130
140 150 160 170 180 190
pF1KE0 EGRE-VCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTER
.:.: . :.:. ::::. : ::. : .: :. ..:..:::.:::::::::. .::.::.
XP_016 RGKEALVENEIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEK
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE0 DATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCL
::.... .:: .: :::.:::.::::::::::: : ::::...:::: : . :. .
XP_016 DASHLVGQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGL-SKIQAGN--M
200 210 220 230 240 250
260 270 280 290 300 310
pF1KE0 MKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGK
. :.:::: :.:::.: .::: ..::.::::::.:::: : :: :.. .:. ::::..
XP_016 LGTACGTPGYVAPELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRAS
260 270 280 290 300 310
320 330 340 350 360 370
pF1KE0 YSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQ
: ... : ..:. ::::: .:: :: :.: ::::: :. . .: . ... :.:.
XP_016 YEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALRHLWISGDTAFD--RDILGSVSE
320 330 340 350 360
380 390 400 410 420
pF1KE0 NLLKRASSRCQSTKSAQSTRSSRSTRSNKSRRVRERELRELNLRYQQQYNG
.. .. .: . .. ..: : :
XP_016 QI-RKNFARTHWKRAFNATSFLRHIRKLGQIPEGEGASEQGMARHSHSGLRAGQPPKW
370 380 390 400 410 420
424 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 03:03:08 2016 done: Sat Nov 5 03:03:10 2016
Total Scan time: 9.940 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]