Result of FASTA (omim) for
pFN21AE0733
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0733, 311 aa
1>>>pF1KE0733 311 - 311 aa - 311 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.6922+/-0.000361; mu= -3.5489+/- 0.022
mean_var=533.7074+/-118.743, 0's: 0 Z-trim(124.0): 806 B-trim: 33 in 1/58
Lambda= 0.055517
statistics sampled from 43548 (44906) to 43548 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.829), E-opt: 0.2 (0.527), width: 16
Scan time: 8.820
The best scores are: opt bits E(85289)
NP_006866 (OMIM: 300295) serine/threonine-protein ( 311) 2214 191.5 1.9e-48
NP_001001852 (OMIM: 610580) serine/threonine-prote ( 326) 1197 110.1 6.4e-24
NP_002639 (OMIM: 164960) serine/threonine-protein ( 313) 1146 105.9 1.1e-22
NP_001230115 (OMIM: 164960) serine/threonine-prote ( 404) 1146 106.1 1.2e-22
XP_005265302 (OMIM: 612760) PREDICTED: SNF-related ( 765) 486 53.7 1.4e-06
NP_060189 (OMIM: 612760) SNF-related serine/threon ( 765) 486 53.7 1.4e-06
NP_001094064 (OMIM: 612760) SNF-related serine/thr ( 765) 486 53.7 1.4e-06
XP_005247048 (OMIM: 607505) PREDICTED: PAS domain- (1107) 483 53.7 2e-06
XP_011509134 (OMIM: 607505) PREDICTED: PAS domain- (1137) 483 53.7 2.1e-06
NP_001239051 (OMIM: 607505) PAS domain-containing (1288) 483 53.8 2.2e-06
XP_016859124 (OMIM: 607505) PREDICTED: PAS domain- (1323) 483 53.8 2.2e-06
NP_001239049 (OMIM: 607505) PAS domain-containing (1323) 483 53.8 2.2e-06
XP_016859125 (OMIM: 607505) PREDICTED: PAS domain- (1323) 483 53.8 2.2e-06
NP_055963 (OMIM: 607505) PAS domain-containing ser (1323) 483 53.8 2.2e-06
XP_016859123 (OMIM: 607505) PREDICTED: PAS domain- (1414) 483 53.8 2.3e-06
NP_001156769 (OMIM: 600526) serine/threonine-prote ( 709) 461 51.6 5.4e-06
NP_001156768 (OMIM: 600526) serine/threonine-prote ( 719) 461 51.6 5.5e-06
NP_004945 (OMIM: 600526) serine/threonine-protein ( 724) 461 51.6 5.5e-06
XP_011543100 (OMIM: 600526) PREDICTED: serine/thre ( 729) 461 51.6 5.5e-06
XP_016872800 (OMIM: 600526) PREDICTED: serine/thre ( 738) 461 51.6 5.6e-06
XP_011543099 (OMIM: 600526) PREDICTED: serine/thre ( 739) 461 51.6 5.6e-06
XP_011543098 (OMIM: 600526) PREDICTED: serine/thre ( 744) 461 51.7 5.6e-06
XP_011543097 (OMIM: 600526) PREDICTED: serine/thre ( 745) 461 51.7 5.6e-06
NP_059672 (OMIM: 600526) serine/threonine-protein ( 745) 461 51.7 5.6e-06
XP_011543096 (OMIM: 600526) PREDICTED: serine/thre ( 753) 461 51.7 5.6e-06
XP_016872799 (OMIM: 600526) PREDICTED: serine/thre ( 763) 461 51.7 5.7e-06
XP_011543095 (OMIM: 600526) PREDICTED: serine/thre ( 784) 461 51.7 5.7e-06
NP_001034558 (OMIM: 600526) serine/threonine-prote ( 788) 461 51.7 5.7e-06
XP_011543094 (OMIM: 600526) PREDICTED: serine/thre ( 793) 461 51.7 5.8e-06
XP_011543093 (OMIM: 600526) PREDICTED: serine/thre ( 798) 461 51.7 5.8e-06
XP_011543092 (OMIM: 600526) PREDICTED: serine/thre ( 799) 461 51.7 5.8e-06
XP_011543091 (OMIM: 600526) PREDICTED: serine/thre ( 808) 461 51.7 5.8e-06
XP_006723370 (OMIM: 606495) PREDICTED: MAP/microtu ( 685) 458 51.4 6.3e-06
NP_113605 (OMIM: 606495) MAP/microtubule affinity- ( 688) 458 51.4 6.3e-06
NP_001186796 (OMIM: 606495) MAP/microtubule affini ( 752) 458 51.4 6.6e-06
NP_006242 (OMIM: 602739) 5'-AMP-activated protein ( 559) 453 50.8 7.5e-06
XP_011509137 (OMIM: 607505) PREDICTED: PAS domain- ( 873) 457 51.4 7.6e-06
XP_011509136 (OMIM: 607505) PREDICTED: PAS domain- ( 944) 457 51.5 7.9e-06
XP_011509135 (OMIM: 607505) PREDICTED: PAS domain- (1114) 457 51.6 8.6e-06
XP_011509133 (OMIM: 607505) PREDICTED: PAS domain- (1144) 457 51.6 8.8e-06
XP_011509130 (OMIM: 607505) PREDICTED: PAS domain- (1330) 457 51.7 9.5e-06
XP_011509132 (OMIM: 607505) PREDICTED: PAS domain- (1330) 457 51.7 9.5e-06
NP_001239048 (OMIM: 607505) PAS domain-containing (1330) 457 51.7 9.5e-06
XP_011509131 (OMIM: 607505) PREDICTED: PAS domain- (1330) 457 51.7 9.5e-06
XP_011509128 (OMIM: 607505) PREDICTED: PAS domain- (1355) 457 51.7 9.6e-06
XP_011527776 (OMIM: 605705,616341) PREDICTED: seri ( 734) 450 50.8 1e-05
NP_775490 (OMIM: 605705,616341) serine/threonine-p ( 783) 450 50.8 1.1e-05
NP_055655 (OMIM: 608130) NUAK family SNF1-like kin ( 661) 448 50.5 1.1e-05
XP_016856796 (OMIM: 606511) PREDICTED: serine/thre ( 670) 448 50.5 1.1e-05
XP_016856795 (OMIM: 606511) PREDICTED: serine/thre ( 685) 448 50.6 1.1e-05
>>NP_006866 (OMIM: 300295) serine/threonine-protein kina (311 aa)
initn: 2214 init1: 2214 opt: 2214 Z-score: 990.8 bits: 191.5 E(85289): 1.9e-48
Smith-Waterman score: 2214; 100.0% identity (100.0% similar) in 311 aa overlap (1-311:1-311)
10 20 30 40 50 60
pF1KE0 MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 PAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 IDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAEDVPLNPSKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAEDVPLNPSKG
250 260 270 280 290 300
310
pF1KE0 GPAPLAWSLLP
:::::::::::
NP_006 GPAPLAWSLLP
310
>>NP_001001852 (OMIM: 610580) serine/threonine-protein k (326 aa)
initn: 1013 init1: 1013 opt: 1197 Z-score: 550.4 bits: 110.1 E(85289): 6.4e-24
Smith-Waterman score: 1197; 61.9% identity (78.0% similar) in 291 aa overlap (6-294:12-301)
10 20 30 40 50
pF1KE0 MLTKPLQGPPAPPGTPTP--PPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRL
: :: . :. :. :.:.:: :..: .::.::::::.:: :.
NP_001 MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 TDRLQVAIKVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGF
.: : ::.: . ..:: :. :. . : ::::.:: ::::.:: :::::::::: .::
NP_001 ADGLPVAVKHVVKERVTEWGSLGGA-TVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGF
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 MLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILID
.:::::: :::::::.:::.: : : .: ::.::.::..:::: :::::::::::.:.:
NP_001 LLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVD
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 LRRGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMV
:: : :::::::::::.: :::::::::::::::: :.::. :::::::.::::::
NP_001 LRSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 CGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAED
:::::::.:.:::...: : .:::.: ::: ::. .:: ::::..: :::
NP_001 CGDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGG
240 250 260 270 280 290
300 310
pF1KE0 VPLNPSKGGPAPLAWSLLP
::
NP_001 VPESCDLRLCTLDPDDVASTTSSSESL
300 310 320
>>NP_002639 (OMIM: 164960) serine/threonine-protein kina (313 aa)
initn: 907 init1: 907 opt: 1146 Z-score: 528.5 bits: 105.9 E(85289): 1.1e-22
Smith-Waterman score: 1146; 56.3% identity (77.2% similar) in 302 aa overlap (6-304:12-311)
10 20 30 40 50
pF1KE0 MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTD
:.. : : ::..: .:..:..:::::.::::.:..: :..:
NP_002 MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 RLQVAIKVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFML
: :::: . ..:. :. : ... :.::.:: ::.. : :::::::::: ..:.:
NP_002 NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSS--GFSGVIRLLDWFERPDSFVL
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 VLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLR
.:::: :.:::::.:::.: : : .: :: ::. :..:::. ::.:::::::::::::
NP_002 ILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 RGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCG
:: :::::::::::.: :::::::::::::::: :.::. :.::::::::::::::
NP_002 RGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 DIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQT---PAE
:::::.:.::..... : .:: .: ::: ::: .::.::..::: :::: : :
NP_002 DIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQE
240 250 260 270 280 290
300 310
pF1KE0 DVPLNPSKGGPAPLAWSLLP
. .. . .:.:
NP_002 TAEIHLHSLSPGPSK
300 310
>>NP_001230115 (OMIM: 164960) serine/threonine-protein k (404 aa)
initn: 1143 init1: 907 opt: 1146 Z-score: 527.4 bits: 106.1 E(85289): 1.2e-22
Smith-Waterman score: 1146; 56.3% identity (77.2% similar) in 302 aa overlap (6-304:103-402)
10 20 30
pF1KE0 MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLG
:.. : : ::..: .:..:..:
NP_001 GSCGSSSGHRPCADILEVGMLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVG
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE0 PLLGKGGFGTVFAGHRLTDRLQVAIKVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGG
::::.::::.:..: :..: : :::: . ..:. :. : ... :.::.:: ::.. :
NP_001 PLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSS--G
140 150 160 170 180 190
100 110 120 130 140 150
pF1KE0 HPGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCH
:::::::::: ..:.:.:::: :.:::::.:::.: : : .: :: ::. :..:::
NP_001 FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCH
200 210 220 230 240 250
160 170 180 190 200 210
pF1KE0 SRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYH
. ::.::::::::::::: :: :::::::::::.: :::::::::::::::: :.::
NP_001 NCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYH
260 270 280 290 300 310
220 230 240 250 260 270
pF1KE0 ALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRP
. :.:::::::::::::::::::.:.::..... : .:: .: ::: ::: .::.::
NP_001 GRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRP
320 330 340 350 360 370
280 290 300 310
pF1KE0 SLEEILLDPWMQT---PAEDVPLNPSKGGPAPLAWSLLP
..::: :::: : : . .. . .:.:
NP_001 TFEEIQNHPWMQDVLLPQETAEIHLHSLSPGPSK
380 390 400
>>XP_005265302 (OMIM: 612760) PREDICTED: SNF-related ser (765 aa)
initn: 461 init1: 203 opt: 486 Z-score: 239.1 bits: 53.7 E(85289): 1.4e-06
Smith-Waterman score: 507; 36.9% identity (62.4% similar) in 282 aa overlap (32-295:16-284)
10 20 30 40 50 60
pF1KE0 LTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTV-FAGHRLTDRLQVAI
: : ::.: :..: .: : .: . .::.
XP_005 MAGFKRGYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGE-KVAV
10 20 30 40
70 80 90 100 110
pF1KE0 KVIPRNRV--LGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLER
::: .... :. . : . : : . :. ::...:: . ..:: ..:.::
XP_005 KVIDKTKLDTLATGHLFQEVRC---MKLVQ-------HPNIVRLYEVIDTQTKLYLILEL
50 60 70 80 90
120 130 140 150 160 170
pF1KE0 PLPAQDLFDYIT--EKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRG
. :.:::: :.: :.: .. .:.:.: ::..::. :::::.: ::... ..:
XP_005 G-DGGDMFDYIMKHEEG-LNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQG
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE0 CAKLIDFG-SGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGD
.:: ::: :. . . : :. .:: :: . .: : . .::::..:. .:::.
XP_005 LVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQ
160 170 180 190 200 210
240 250 260 270 280
pF1KE0 IPFER--DQE----ILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQ--
::.. :.: :.. . :.::: .: :: : : :. : ::::: ::.:
XP_005 PPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRDPKRRASLEEIENHPWLQGV
220 230 240 250 260 270
290 300 310
pF1KE0 --TPAE--DVPLNPSKGGPAPLAWSLLP
.:: ..::
XP_005 DPSPATKYNIPLVSYKNLSEEEHNSIIQRMVLGDIADRDAIVEALETNRYNHITATYFLL
280 290 300 310 320 330
>>NP_060189 (OMIM: 612760) SNF-related serine/threonine- (765 aa)
initn: 461 init1: 203 opt: 486 Z-score: 239.1 bits: 53.7 E(85289): 1.4e-06
Smith-Waterman score: 507; 36.9% identity (62.4% similar) in 282 aa overlap (32-295:16-284)
10 20 30 40 50 60
pF1KE0 LTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTV-FAGHRLTDRLQVAI
: : ::.: :..: .: : .: . .::.
NP_060 MAGFKRGYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGE-KVAV
10 20 30 40
70 80 90 100 110
pF1KE0 KVIPRNRV--LGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLER
::: .... :. . : . : : . :. ::...:: . ..:: ..:.::
NP_060 KVIDKTKLDTLATGHLFQEVRC---MKLVQ-------HPNIVRLYEVIDTQTKLYLILEL
50 60 70 80 90
120 130 140 150 160 170
pF1KE0 PLPAQDLFDYIT--EKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRG
. :.:::: :.: :.: .. .:.:.: ::..::. :::::.: ::... ..:
NP_060 G-DGGDMFDYIMKHEEG-LNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQG
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE0 CAKLIDFG-SGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGD
.:: ::: :. . . : :. .:: :: . .: : . .::::..:. .:::.
NP_060 LVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQ
160 170 180 190 200 210
240 250 260 270 280
pF1KE0 IPFER--DQE----ILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQ--
::.. :.: :.. . :.::: .: :: : : :. : ::::: ::.:
NP_060 PPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRDPKRRASLEEIENHPWLQGV
220 230 240 250 260 270
290 300 310
pF1KE0 --TPAE--DVPLNPSKGGPAPLAWSLLP
.:: ..::
NP_060 DPSPATKYNIPLVSYKNLSEEEHNSIIQRMVLGDIADRDAIVEALETNRYNHITATYFLL
280 290 300 310 320 330
>>NP_001094064 (OMIM: 612760) SNF-related serine/threoni (765 aa)
initn: 461 init1: 203 opt: 486 Z-score: 239.1 bits: 53.7 E(85289): 1.4e-06
Smith-Waterman score: 507; 36.9% identity (62.4% similar) in 282 aa overlap (32-295:16-284)
10 20 30 40 50 60
pF1KE0 LTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTV-FAGHRLTDRLQVAI
: : ::.: :..: .: : .: . .::.
NP_001 MAGFKRGYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGE-KVAV
10 20 30 40
70 80 90 100 110
pF1KE0 KVIPRNRV--LGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLER
::: .... :. . : . : : . :. ::...:: . ..:: ..:.::
NP_001 KVIDKTKLDTLATGHLFQEVRC---MKLVQ-------HPNIVRLYEVIDTQTKLYLILEL
50 60 70 80 90
120 130 140 150 160 170
pF1KE0 PLPAQDLFDYIT--EKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRG
. :.:::: :.: :.: .. .:.:.: ::..::. :::::.: ::... ..:
NP_001 G-DGGDMFDYIMKHEEG-LNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQG
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE0 CAKLIDFG-SGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGD
.:: ::: :. . . : :. .:: :: . .: : . .::::..:. .:::.
NP_001 LVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQ
160 170 180 190 200 210
240 250 260 270 280
pF1KE0 IPFER--DQE----ILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQ--
::.. :.: :.. . :.::: .: :: : : :. : ::::: ::.:
NP_001 PPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRDPKRRASLEEIENHPWLQGV
220 230 240 250 260 270
290 300 310
pF1KE0 --TPAE--DVPLNPSKGGPAPLAWSLLP
.:: ..::
NP_001 DPSPATKYNIPLVSYKNLSEEEHNSIIQRMVLGDIADRDAIVEALETNRYNHITATYFLL
280 290 300 310 320 330
>>XP_005247048 (OMIM: 607505) PREDICTED: PAS domain-cont (1107 aa)
initn: 440 init1: 351 opt: 483 Z-score: 236.2 bits: 53.7 E(85289): 2e-06
Smith-Waterman score: 483; 35.9% identity (60.2% similar) in 284 aa overlap (19-289:763-1038)
10 20 30 40
pF1KE0 MLTKPLQGPPAPPGTPTPPPGGKDRE---AFEAEYR-----LGPLLGK
:: . . : : :.:: ..:: :.
XP_005 SLPGSTHSTAAELTGPSLVEVLRARPWFEEPPKAVELEGLAACEGEYSQKYSTMSPL-GS
740 750 760 770 780 790
50 60 70 80 90
pF1KE0 GGFGTVFAGHRLTDRLQVAIKVIPRNRVLG--W--SPLSDSVTCPLEVALLWKVGAGGGH
:.:: :... .:..: : ...:: : .: .:: ::.:.: .: :
XP_005 GAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVT--LEIAILSRVE----H
800 810 820 830 840
100 110 120 130 140 150
pF1KE0 PGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHS
..:..:: ::.: :.::.:. . ::: .: .. : : . .: :.:.:. . .
XP_005 ANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRL
850 860 870 880 890 900
160 170 180 190 200 210
pF1KE0 RGVVHRDIKDENILIDLRRGCAKLIDFGSGALLH-DEPYTDFDGTRVYSPPEWISRHQYH
. ..:::::::::.: . :::::::.: :. . . : :: : :: . . :.
XP_005 KDIIHRDIKDENIVIA-EDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYR
910 920 930 940 950 960
220 230 240 250 260 270
pF1KE0 ALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRP
. .::::. :: .: . :: . .: .:: .: : :: . .:. : : : :
XP_005 GPELEMWSLGVTLYTLVFEENPFCELEETVEAAIHPPYLVSKELMSLVSGLLQPVPERRT
970 980 990 1000 1010 1020
280 290 300 310
pF1KE0 SLEEILLDPWMQTPAEDVPLNPSKGGPAPLAWSLLP
.::... :::. :
XP_005 TLEKLVTDPWVTQPVNLADYTWEEVFRVNKPESGVLSAASLEMGNRSLSDVAQAQELCGG
1030 1040 1050 1060 1070 1080
>>XP_011509134 (OMIM: 607505) PREDICTED: PAS domain-cont (1137 aa)
initn: 440 init1: 351 opt: 483 Z-score: 236.1 bits: 53.7 E(85289): 2.1e-06
Smith-Waterman score: 483; 35.9% identity (60.2% similar) in 284 aa overlap (19-289:793-1068)
10 20 30 40
pF1KE0 MLTKPLQGPPAPPGTPTPPPGGKDRE---AFEAEYR-----LGPLLGK
:: . . : : :.:: ..:: :.
XP_011 SLPGSTHSTAAELTGPSLVEVLRARPWFEEPPKAVELEGLAACEGEYSQKYSTMSPL-GS
770 780 790 800 810 820
50 60 70 80 90
pF1KE0 GGFGTVFAGHRLTDRLQVAIKVIPRNRVLG--W--SPLSDSVTCPLEVALLWKVGAGGGH
:.:: :... .:..: : ...:: : .: .:: ::.:.: .: :
XP_011 GAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVT--LEIAILSRVE----H
830 840 850 860 870
100 110 120 130 140 150
pF1KE0 PGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHS
..:..:: ::.: :.::.:. . ::: .: .. : : . .: :.:.:. . .
XP_011 ANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRL
880 890 900 910 920 930
160 170 180 190 200 210
pF1KE0 RGVVHRDIKDENILIDLRRGCAKLIDFGSGALLH-DEPYTDFDGTRVYSPPEWISRHQYH
. ..:::::::::.: . :::::::.: :. . . : :: : :: . . :.
XP_011 KDIIHRDIKDENIVIA-EDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYR
940 950 960 970 980 990
220 230 240 250 260 270
pF1KE0 ALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRP
. .::::. :: .: . :: . .: .:: .: : :: . .:. : : : :
XP_011 GPELEMWSLGVTLYTLVFEENPFCELEETVEAAIHPPYLVSKELMSLVSGLLQPVPERRT
1000 1010 1020 1030 1040 1050
280 290 300 310
pF1KE0 SLEEILLDPWMQTPAEDVPLNPSKGGPAPLAWSLLP
.::... :::. :
XP_011 TLEKLVTDPWVTQPVNLADYTWEEVFRVNKPESGVLSAASLEMGNRSLSDVAQAQELCGG
1060 1070 1080 1090 1100 1110
>>NP_001239051 (OMIM: 607505) PAS domain-containing seri (1288 aa)
initn: 419 init1: 351 opt: 483 Z-score: 235.6 bits: 53.8 E(85289): 2.2e-06
Smith-Waterman score: 483; 35.9% identity (60.2% similar) in 284 aa overlap (19-289:944-1219)
10 20 30 40
pF1KE0 MLTKPLQGPPAPPGTPTPPPGGKDRE---AFEAEYR-----LGPLLGK
:: . . : : :.:: ..:: :.
NP_001 SLPGSTHSTAAELTGPSLVEVLRARPWFEEPPKAVELEGLAACEGEYSQKYSTMSPL-GS
920 930 940 950 960 970
50 60 70 80 90
pF1KE0 GGFGTVFAGHRLTDRLQVAIKVIPRNRVLG--W--SPLSDSVTCPLEVALLWKVGAGGGH
:.:: :... .:..: : ...:: : .: .:: ::.:.: .: :
NP_001 GAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVT--LEIAILSRVE----H
980 990 1000 1010 1020
100 110 120 130 140 150
pF1KE0 PGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHS
..:..:: ::.: :.::.:. . ::: .: .. : : . .: :.:.:. . .
NP_001 ANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRL
1030 1040 1050 1060 1070 1080
160 170 180 190 200 210
pF1KE0 RGVVHRDIKDENILIDLRRGCAKLIDFGSGALLH-DEPYTDFDGTRVYSPPEWISRHQYH
. ..:::::::::.: . :::::::.: :. . . : :: : :: . . :.
NP_001 KDIIHRDIKDENIVIA-EDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYR
1090 1100 1110 1120 1130 1140
220 230 240 250 260 270
pF1KE0 ALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRP
. .::::. :: .: . :: . .: .:: .: : :: . .:. : : : :
NP_001 GPELEMWSLGVTLYTLVFEENPFCELEETVEAAIHPPYLVSKELMSLVSGLLQPVPERRT
1150 1160 1170 1180 1190 1200
280 290 300 310
pF1KE0 SLEEILLDPWMQTPAEDVPLNPSKGGPAPLAWSLLP
.::... :::. :
NP_001 TLEKLVTDPWVTQPVNLADYTWEEVFRVNKPESGVLSAASLEMGNRSLSDVAQAQELCGG
1210 1220 1230 1240 1250 1260
311 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 03:01:02 2016 done: Sat Nov 5 03:01:03 2016
Total Scan time: 8.820 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]