Result of FASTA (omim) for
pFN21AE0712
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0712, 411 aa
1>>>pF1KE0712 411 - 411 aa - 411 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.1214+/-0.000327; mu= -2.8340+/- 0.021
mean_var=346.8769+/-73.226, 0's: 0 Z-trim(125.2): 16 B-trim: 0 in 0/61
Lambda= 0.068863
statistics sampled from 48469 (48488) to 48469 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.836), E-opt: 0.2 (0.569), width: 16
Scan time: 11.420
The best scores are: opt bits E(85289)
XP_011532340 (OMIM: 602317) PREDICTED: SH3 and cys ( 334) 985 111.0 4.5e-24
XP_016862572 (OMIM: 602317) PREDICTED: SH3 and cys ( 334) 985 111.0 4.5e-24
XP_011532339 (OMIM: 602317) PREDICTED: SH3 and cys ( 391) 985 111.1 5e-24
NP_003140 (OMIM: 602317) SH3 and cysteine-rich dom ( 402) 985 111.1 5.1e-24
XP_011532338 (OMIM: 602317) PREDICTED: SH3 and cys ( 406) 985 111.1 5.1e-24
NP_001278978 (OMIM: 602317) SH3 and cysteine-rich ( 341) 679 80.6 6.4e-15
XP_016862573 (OMIM: 602317) PREDICTED: SH3 and cys ( 215) 670 79.5 8.7e-15
NP_001273185 (OMIM: 255995,615521) SH3 and cystein ( 325) 467 59.5 1.4e-08
NP_659501 (OMIM: 255995,615521) SH3 and cysteine-r ( 364) 467 59.6 1.5e-08
XP_011536428 (OMIM: 255995,615521) PREDICTED: SH3 ( 364) 467 59.6 1.5e-08
NP_001273186 (OMIM: 255995,615521) SH3 and cystein ( 178) 448 57.4 3.3e-08
>>XP_011532340 (OMIM: 602317) PREDICTED: SH3 and cystein (334 aa)
initn: 878 init1: 452 opt: 985 Z-score: 553.2 bits: 111.0 E(85289): 4.5e-24
Smith-Waterman score: 985; 48.4% identity (71.8% similar) in 337 aa overlap (90-411:12-334)
60 70 80 90 100 110
pF1KE0 LKCPTEVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPL------AALKPV-RLHS
.:: :: :.: : :.:.: . :.
XP_011 MKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHA
10 20 30 40
120 130 140 150 160 170
pF1KE0 FQEHVFKRASPCELCHQLIVG-NSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSFRR
:::..::. . :..:...::: :.:.::::: ::.:.: :.. .. :.: :: .:::
XP_011 FQEYIFKKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRR
50 60 70 80 90 100
180 190 200 210 220 230
pF1KE0 NFSSPLLVHEPPPVCATSKESPPTGDSGKVDPVYETLRYGTSLAL-MNRSSFSSTSESPT
.:::::.:: : :: : . ..::::::::::.::::: ...: .: :.::
XP_011 YYSSPLLIHEQFG-CI--KEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPH
110 120 130 140 150
240 250 260 270 280
pF1KE0 R-SLSERDELTEDGEGSIRSSEEGPG----DSASPVFTAPAESEGPGPEEKSPGQQLP-K
: : :. :. :...: : : .. ::: : :. . ..:.... .
XP_011 RTSTSDLVEVPEEANGP------GGGYDLRKRSNSVFTYP---ENGTDDFRDPAKNINHQ
160 170 180 190 200
290 300 310 320 330 340
pF1KE0 ATLRKDVGPMYSYVALYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFPAN
..: :: : .:::::::.::::.:: ..::: : :..::::::::::: ::.::::::
XP_011 GSLSKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPAN
210 220 230 240 250 260
350 360 370 380 390 400
pF1KE0 FVQRVRPGENVWRCCQPFSGNKEQGYMSLKENQICVGVGRSKDADGFIRVSSGKKRGLVP
::::.. .:...:: . : : :::: ..::::::::. .. :::::: ::::.::.:
XP_011 FVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVS--SEEEQDGFIRVLSGKKKGLIP
270 280 290 300 310 320
410
pF1KE0 VDALTEI
.:.: .:
XP_011 LDVLENI
330
>>XP_016862572 (OMIM: 602317) PREDICTED: SH3 and cystein (334 aa)
initn: 878 init1: 452 opt: 985 Z-score: 553.2 bits: 111.0 E(85289): 4.5e-24
Smith-Waterman score: 985; 48.4% identity (71.8% similar) in 337 aa overlap (90-411:12-334)
60 70 80 90 100 110
pF1KE0 LKCPTEVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPL------AALKPV-RLHS
.:: :: :.: : :.:.: . :.
XP_016 MKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHA
10 20 30 40
120 130 140 150 160 170
pF1KE0 FQEHVFKRASPCELCHQLIVG-NSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSFRR
:::..::. . :..:...::: :.:.::::: ::.:.: :.. .. :.: :: .:::
XP_016 FQEYIFKKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRR
50 60 70 80 90 100
180 190 200 210 220 230
pF1KE0 NFSSPLLVHEPPPVCATSKESPPTGDSGKVDPVYETLRYGTSLAL-MNRSSFSSTSESPT
.:::::.:: : :: : . ..::::::::::.::::: ...: .: :.::
XP_016 YYSSPLLIHEQFG-CI--KEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPH
110 120 130 140 150
240 250 260 270 280
pF1KE0 R-SLSERDELTEDGEGSIRSSEEGPG----DSASPVFTAPAESEGPGPEEKSPGQQLP-K
: : :. :. :...: : : .. ::: : :. . ..:.... .
XP_016 RTSTSDLVEVPEEANGP------GGGYDLRKRSNSVFTYP---ENGTDDFRDPAKNINHQ
160 170 180 190 200
290 300 310 320 330 340
pF1KE0 ATLRKDVGPMYSYVALYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFPAN
..: :: : .:::::::.::::.:: ..::: : :..::::::::::: ::.::::::
XP_016 GSLSKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPAN
210 220 230 240 250 260
350 360 370 380 390 400
pF1KE0 FVQRVRPGENVWRCCQPFSGNKEQGYMSLKENQICVGVGRSKDADGFIRVSSGKKRGLVP
::::.. .:...:: . : : :::: ..::::::::. .. :::::: ::::.::.:
XP_016 FVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVS--SEEEQDGFIRVLSGKKKGLIP
270 280 290 300 310 320
410
pF1KE0 VDALTEI
.:.: .:
XP_016 LDVLENI
330
>>XP_011532339 (OMIM: 602317) PREDICTED: SH3 and cystein (391 aa)
initn: 898 init1: 452 opt: 985 Z-score: 552.4 bits: 111.1 E(85289): 5e-24
Smith-Waterman score: 1021; 44.1% identity (67.8% similar) in 410 aa overlap (12-411:9-391)
10 20 30 40 50
pF1KE0 MTEMSEKENEPDDAATHSPPGTVSALQETKLQRFKRSLSLKTILRSKSLENFFLRSGSE-
.:.. : .:.: : . . . : ::::: .::: :..::
XP_011 MIPPSSPREDGVDGLPKEAVGAEQPPSPASTSSQESKTKSLRSKSADNFFQRTNSED
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LKCPTEVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPLAALKPV-RLHSFQEHVF
.: .. ... .: : : : : : .:. :.:.: . :.:::..:
XP_011 MKLQAH-MVAEISPSSSPLPAP-----GSLTSTPAR-------AGLHPGGKAHAFQEYIF
60 70 80 90 100
120 130 140 150 160 170
pF1KE0 KRASPCELCHQLIVG-NSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSFRRNFSSPL
:. . :..:...::: :.:.::::: ::.:.: :.. .. :.: :: .::: .::::
XP_011 KKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPL
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE0 LVHEPPPVCATSKESPPTGDSGKVDPVYETLRYGTSLAL-MNRSSFSSTSESPTR-SLSE
:.:: : :: : . ..::::::::::.::::: ...: .: :.:: : : :.
XP_011 LIHEQFG-CI--KEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSD
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE0 RDELTEDGEGSIRSSEEGPG----DSASPVFTAPAESEGPGPEEKSPGQQLP-KATLRKD
:. :...: : : .. ::: : :. . ..:.... ...: ::
XP_011 LVEVPEEANGP------GGGYDLRKRSNSVFTYP---ENGTDDFRDPAKNINHQGSLSKD
230 240 250 260 270
300 310 320 330 340 350
pF1KE0 VGPMYSYVALYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFPANFVQRVR
: .:::::::.::::.:: ..::: : :..::::::::::: ::.::::::::::..
XP_011 PLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQ
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE0 PGENVWRCCQPFSGNKEQGYMSLKENQICVGVGRSKDADGFIRVSSGKKRGLVPVDALTE
.:...:: . : : :::: ..:::::::: . .. :::::: ::::.::.:.:.: .
XP_011 QNEKIFRCVRTFIGCKEQGQITLKENQICV--SSEEEQDGFIRVLSGKKKGLIPLDVLEN
340 350 360 370 380 390
pF1KE0 I
:
XP_011 I
>>NP_003140 (OMIM: 602317) SH3 and cysteine-rich domain- (402 aa)
initn: 961 init1: 452 opt: 985 Z-score: 552.2 bits: 111.1 E(85289): 5.1e-24
Smith-Waterman score: 1090; 46.4% identity (70.8% similar) in 414 aa overlap (11-411:16-402)
10 20 30 40 50
pF1KE0 MTEMSEKENEPDDAA-THSPPGTVS-ALQETKLQRFKRSLSLKTI-LRSKSLENF
: .:. ...::. .: . ::.:::..:::::.:: ::::: .::
NP_003 MIPPSSPREDGVDGLPKEAVGAEQPPSPASTSSQESKLQKLKRSLSFKTKSLRSKSADNF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 FLRSGSE-LKCPTEVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPLAALKPV-RL
: :..:: .: .. ... .: : : : : : .:. :.:.: .
NP_003 FQRTNSEDMKLQAH-MVAEISPSSSPLPAP-----GSLTSTPAR-------AGLHPGGKA
70 80 90 100
120 130 140 150 160
pF1KE0 HSFQEHVFKRASPCELCHQLIVG-NSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSF
:.:::..::. . :..:...::: :.:.::::: ::.:.: :.. .. :.: :: .:
NP_003 HAFQEYIFKKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGF
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE0 RRNFSSPLLVHEPPPVCATSKESPPTGDSGKVDPVYETLRYGTSLAL-MNRSSFSSTSES
:: .:::::.:: : :: : . ..::::::::::.::::: ...: .: :.:
NP_003 RRYYSSPLLIHEQFG-CI--KEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDS
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE0 PTR-SLSERDELTEDGEGSIRSSEEGPG----DSASPVFTAPAESEGPGPEEKSPGQQLP
: : : :. :. :...: : : .. ::: : :. . ..:....
NP_003 PHRTSTSDLVEVPEEANGP------GGGYDLRKRSNSVFTYP---ENGTDDFRDPAKNIN
230 240 250 260 270
290 300 310 320 330 340
pF1KE0 -KATLRKDVGPMYSYVALYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFP
...: :: : .:::::::.::::.:: ..::: : :..::::::::::: ::.::::
NP_003 HQGSLSKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFP
280 290 300 310 320 330
350 360 370 380 390 400
pF1KE0 ANFVQRVRPGENVWRCCQPFSGNKEQGYMSLKENQICVGVGRSKDADGFIRVSSGKKRGL
::::::.. .:...:: . : : :::: ..::::::::. .. :::::: ::::.::
NP_003 ANFVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVS--SEEEQDGFIRVLSGKKKGL
340 350 360 370 380 390
410
pF1KE0 VPVDALTEI
.:.:.: .:
NP_003 IPLDVLENI
400
>>XP_011532338 (OMIM: 602317) PREDICTED: SH3 and cystein (406 aa)
initn: 977 init1: 452 opt: 985 Z-score: 552.2 bits: 111.1 E(85289): 5.1e-24
Smith-Waterman score: 1057; 47.1% identity (70.7% similar) in 393 aa overlap (30-411:41-406)
10 20 30 40 50
pF1KE0 MTEMSEKENEPDDAATHSPPGTVSALQETKLQRFKRSLSLKTI-LRSKSLENFFLRSGS
.::..:::::.:: ::::: .::: :..:
XP_011 ISCIHSIHPRASWGKIEEASHALNYQGNIFQLQKLKRSLSFKTKSLRSKSADNFFQRTNS
20 30 40 50 60 70
60 70 80 90 100 110
pF1KE0 E-LKCPTEVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPLAALKPV-RLHSFQEH
: .: .. ... .: : : : : : .:. : :.:.: . :.:::.
XP_011 EDMKLQAH-MVAEISPSSSPLPAP-----GSLTSTPA-----R--AGLHPGGKAHAFQEY
80 90 100 110
120 130 140 150 160 170
pF1KE0 VFKRASPCELCHQLIVG-NSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSFRRNFSS
.::. . :..:...::: :.:.::::: ::.:.: :.. .. :.: :: .::: .::
XP_011 IFKKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 PLLVHEPPPVCATSKESPPTGDSGKVDPVYETLRYGTSLAL-MNRSSFSSTSESPTR-SL
:::.:: : :: : . ..::::::::::.::::: ...: .: :.:: : :
XP_011 PLLIHEQFG-CI--KEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTST
180 190 200 210 220 230
240 250 260 270 280
pF1KE0 SERDELTEDGEGSIRSSEEGPG----DSASPVFTAPAESEGPGPEEKSPGQQLP-KATLR
:. :. :...: : : .. ::: : :. . ..:.... ...:
XP_011 SDLVEVPEEANGP------GGGYDLRKRSNSVFTYP---ENGTDDFRDPAKNINHQGSLS
240 250 260 270 280
290 300 310 320 330 340
pF1KE0 KDVGPMYSYVALYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFPANFVQR
:: : .:::::::.::::.:: ..::: : :..::::::::::: ::.::::::::::
XP_011 KDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQR
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE0 VRPGENVWRCCQPFSGNKEQGYMSLKENQICVGVGRSKDADGFIRVSSGKKRGLVPVDAL
.. .:...:: . : : :::: ..::::::::. .. :::::: ::::.::.:.:.:
XP_011 LQQNEKIFRCVRTFIGCKEQGQITLKENQICVS--SEEEQDGFIRVLSGKKKGLIPLDVL
350 360 370 380 390 400
410
pF1KE0 TEI
.:
XP_011 ENI
>>NP_001278978 (OMIM: 602317) SH3 and cysteine-rich doma (341 aa)
initn: 842 init1: 452 opt: 679 Z-score: 388.8 bits: 80.6 E(85289): 6.4e-15
Smith-Waterman score: 766; 39.2% identity (60.8% similar) in 413 aa overlap (11-411:16-341)
10 20 30 40 50
pF1KE0 MTEMSEKENEPDDAA-THSPPGTVS-ALQETKLQRFKRSLSLKTI-LRSKSLENF
: .:. ...::. .: . ::.:::..:::::.:: ::::: .::
NP_001 MIPPSSPREDGVDGLPKEAVGAEQPPSPASTSSQESKLQKLKRSLSFKTKSLRSKSADNF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 FLRSGSE-LKCPTEVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPLAALKPV-RL
: :..:: .: .. ... .: : : : : : .:. :.:.: .
NP_001 FQRTNSEDMKLQAH-MVAEISPSSSPLPAP-----GSLTSTPAR-------AGLHPGGKA
70 80 90 100
120 130 140 150 160 170
pF1KE0 HSFQEHVFKRASPCELCHQLIVGNSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSFR
:.:::..::. . :..:...::. :
NP_001 HAFQEYIFKKPTFCDVCNHMIVA---------------------------C---------
110 120 130
180 190 200 210 220
pF1KE0 RNFSSPLLVHEPPPVCATSKESPPTGDSGKVDPVYETLRYGTSLAL-MNRSSFSSTSESP
..::::::::::.::::: ...: .: :.::
NP_001 ---------------------------GNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSP
140 150 160
230 240 250 260 270 280
pF1KE0 TR-SLSERDELTEDGEGSIRSSEEGPG----DSASPVFTAPAESEGPGPEEKSPGQQLP-
: : :. :. :...: : : .. ::: : :. . ..:....
NP_001 HRTSTSDLVEVPEEANGP------GGGYDLRKRSNSVFTYP---ENGTDDFRDPAKNINH
170 180 190 200 210
290 300 310 320 330 340
pF1KE0 KATLRKDVGPMYSYVALYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFPA
...: :: : .:::::::.::::.:: ..::: : :..::::::::::: ::.:::::
NP_001 QGSLSKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPA
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE0 NFVQRVRPGENVWRCCQPFSGNKEQGYMSLKENQICVGVGRSKDADGFIRVSSGKKRGLV
:::::.. .:...:: . : : :::: ..::::::::. .. :::::: ::::.::.
NP_001 NFVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVS--SEEEQDGFIRVLSGKKKGLI
280 290 300 310 320 330
410
pF1KE0 PVDALTEI
:.:.: .:
NP_001 PLDVLENI
340
>>XP_016862573 (OMIM: 602317) PREDICTED: SH3 and cystein (215 aa)
initn: 641 init1: 452 opt: 670 Z-score: 386.5 bits: 79.5 E(85289): 8.7e-15
Smith-Waterman score: 670; 50.2% identity (73.3% similar) in 225 aa overlap (194-411:2-215)
170 180 190 200 210 220
pF1KE0 KTSTSFRRNFSSPLLVHEPPPVCATSKESPPTGDSGKVDPVYETLRYGTSLAL-MNRSSF
: . ..::::::::::.::::: ...:
XP_016 MPIACGNKVDPVYETLRFGTSLAQRTKKGSS
10 20 30
230 240 250 260 270
pF1KE0 SSTSESPTR-SLSERDELTEDGEGSIRSSEEGPG----DSASPVFTAPAESEGPGPEEKS
.: :.:: : : :. :. :...: : : .. ::: : :. . ..
XP_016 GSGSDSPHRTSTSDLVEVPEEANGP------GGGYDLRKRSNSVFTYP---ENGTDDFRD
40 50 60 70 80
280 290 300 310 320 330
pF1KE0 PGQQLP-KATLRKDVGPMYSYVALYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGD
:.... ...: :: : .:::::::.::::.:: ..::: : :..::::::::::: :
XP_016 PAKNINHQGSLSKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQD
90 100 110 120 130 140
340 350 360 370 380 390
pF1KE0 RVGFFPANFVQRVRPGENVWRCCQPFSGNKEQGYMSLKENQICVGVGRSKDADGFIRVSS
:.::::::::::.. .:...:: . : : :::: ..::::::::. .. :::::: :
XP_016 RIGFFPANFVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVS--SEEEQDGFIRVLS
150 160 170 180 190 200
400 410
pF1KE0 GKKRGLVPVDALTEI
:::.::.:.:.: .:
XP_016 GKKKGLIPLDVLENI
210
>>NP_001273185 (OMIM: 255995,615521) SH3 and cysteine-ri (325 aa)
initn: 758 init1: 340 opt: 467 Z-score: 275.2 bits: 59.5 E(85289): 1.4e-08
Smith-Waterman score: 732; 38.8% identity (64.4% similar) in 317 aa overlap (95-411:38-325)
70 80 90 100 110 120
pF1KE0 EVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPLAALKPVRLHSFQEHVFKRASPC
: : : :. :: :.:..: ::. . :
NP_001 QANGEAVGAGGGPIYYIYEEEEEEEEEEEEPPPEPPKLVNDKP---HKFKDHFFKKPKFC
10 20 30 40 50 60
130 140 150 160 170 180
pF1KE0 ELCHQLIVGNSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSFRRNFSSPLLVHEPPP
..: ..:: :.: ::::: ::...: :. . :.: :: .:.: .:::: ..
NP_001 DVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQY-
70 80 90 100 110 120
190 200 210 220 230 240
pF1KE0 VCATSKESPPTGDSGKVDPVYETLRYGTSLALMNRSSFSSTSESPTRSLSERDELTEDGE
.:. . . ... :::.:::: :. .: .:.. .. ...:. .. : :. :
NP_001 ACVKDLSA-----ANRNDPVFETLRTGVIMANKERKKGQADKKNPVAAMME-----EEPE
130 140 150 160 170
250 260 270 280 290 300
pF1KE0 GSIRSSEEGPGDSASPVFTAPAESEGPGPEEKSPGQQLPKATLRKDVGPMYSYVALYKFL
: : ::: ....: ::.. : ..:.:: : . .::::.:
NP_001 -SARP-EEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQS-----------HYFVALYRFK
180 190 200 210 220
310 320 330 340 350 360
pF1KE0 PQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFPANFVQRVRPGENVWRCCQPFSG
:..:: . ::..: ..:::::.::.::::..::::: ::. ::: :: : : . : :
NP_001 ALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVG
230 240 250 260 270 280
370 380 390 400 410
pF1KE0 NKEQGYMSLKENQICVGVGRSKDADGFIRVSSGKKRGLVPVDALTEI
:.: : ..::..:: : : .: :...: .:.: :: :.: : ::
NP_001 NREIGQITLKKDQIVVQKG--DEAGGYVKVYTGRKVGLFPTDFLEEI
290 300 310 320
>>NP_659501 (OMIM: 255995,615521) SH3 and cysteine-rich (364 aa)
initn: 758 init1: 340 opt: 467 Z-score: 274.6 bits: 59.6 E(85289): 1.5e-08
Smith-Waterman score: 735; 34.7% identity (59.7% similar) in 409 aa overlap (4-411:1-364)
10 20 30 40 50
pF1KE0 MTEMSEKENEPDDAATHSP-PGTVSALQETKLQRFKRSLSLKTILRSKSLENFFLRSGSE
:.::: . .:: :. . ... ::: :: .::. : . .. :
NP_659 MTEKE------VLESPKPSFPAETRQSGLQR------LKQLLRKGSTGTKEMELPPE
10 20 30 40
60 70 80 90 100 110
pF1KE0 LKCPTEVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPLAALKPVRLHSFQEHVFK
. :.. . :. .. : : : :. :. :: :.:..: ::
NP_659 PQANGEAVGAGGGPIYYIYEEEEEEEEEEEEPPPEP---PK-LVNDKP---HKFKDHFFK
50 60 70 80 90
120 130 140 150 160 170
pF1KE0 RASPCELCHQLIVGNSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSFRRNFSSPLLV
. . :..: ..:: :.: ::::: ::...: :. . :.: :: .:.: .::::
NP_659 KPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYS
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE0 HEPPPVCATSKESPPTGDSGKVDPVYETLRYGTSLALMNRSSFSSTSESPTRSLSERDEL
.. .:. . . ... :::.:::: :. .: .:.. .. ...:. .. :
NP_659 NQQY-ACVKD-----LSAANRNDPVFETLRTGVIMANKERKKGQADKKNPVAAMME----
160 170 180 190 200
240 250 260 270 280 290
pF1KE0 TEDGEGSIRSSEEGPGDSASPVFTAPAESEGPGPEEKSPGQQLPKATLRKDVGPMYSYVA
:. : : : ::: ....: ::.. : ..:.:: : . .::
NP_659 -EEPE-SARP-EEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQS-----------HYFVA
210 220 230 240 250
300 310 320 330 340 350
pF1KE0 LYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFPANFVQRVRPGENVWRCC
::.: :..:: . ::..: ..:::::.::.::::..::::: ::. ::: :: : :
NP_659 LYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVT
260 270 280 290 300 310
360 370 380 390 400 410
pF1KE0 QPFSGNKEQGYMSLKENQICVGVGRSKDADGFIRVSSGKKRGLVPVDALTEI
. : ::.: : ..::..:: : : .: :...: .:.: :: :.: : ::
NP_659 RSFVGNREIGQITLKKDQIVVQKG--DEAGGYVKVYTGRKVGLFPTDFLEEI
320 330 340 350 360
>>XP_011536428 (OMIM: 255995,615521) PREDICTED: SH3 and (364 aa)
initn: 758 init1: 340 opt: 467 Z-score: 274.6 bits: 59.6 E(85289): 1.5e-08
Smith-Waterman score: 735; 34.7% identity (59.7% similar) in 409 aa overlap (4-411:1-364)
10 20 30 40 50
pF1KE0 MTEMSEKENEPDDAATHSP-PGTVSALQETKLQRFKRSLSLKTILRSKSLENFFLRSGSE
:.::: . .:: :. . ... ::: :: .::. : . .. :
XP_011 MTEKE------VLESPKPSFPAETRQSGLQR------LKQLLRKGSTGTKEMELPPE
10 20 30 40
60 70 80 90 100 110
pF1KE0 LKCPTEVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPLAALKPVRLHSFQEHVFK
. :.. . :. .. : : : :. :. :: :.:..: ::
XP_011 PQANGEAVGAGGGPIYYIYEEEEEEEEEEEEPPPEP---PK-LVNDKP---HKFKDHFFK
50 60 70 80 90
120 130 140 150 160 170
pF1KE0 RASPCELCHQLIVGNSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSFRRNFSSPLLV
. . :..: ..:: :.: ::::: ::...: :. . :.: :: .:.: .::::
XP_011 KPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYS
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE0 HEPPPVCATSKESPPTGDSGKVDPVYETLRYGTSLALMNRSSFSSTSESPTRSLSERDEL
.. .:. . . ... :::.:::: :. .: .:.. .. ...:. .. :
XP_011 NQQY-ACVKD-----LSAANRNDPVFETLRTGVIMANKERKKGQADKKNPVAAMME----
160 170 180 190 200
240 250 260 270 280 290
pF1KE0 TEDGEGSIRSSEEGPGDSASPVFTAPAESEGPGPEEKSPGQQLPKATLRKDVGPMYSYVA
:. : : : ::: ....: ::.. : ..:.:: : . .::
XP_011 -EEPE-SARP-EEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQS-----------HYFVA
210 220 230 240 250
300 310 320 330 340 350
pF1KE0 LYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFPANFVQRVRPGENVWRCC
::.: :..:: . ::..: ..:::::.::.::::..::::: ::. ::: :: : :
XP_011 LYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVT
260 270 280 290 300 310
360 370 380 390 400 410
pF1KE0 QPFSGNKEQGYMSLKENQICVGVGRSKDADGFIRVSSGKKRGLVPVDALTEI
. : ::.: : ..::..:: : : .: :...: .:.: :: :.: : ::
XP_011 RSFVGNREIGQITLKKDQIVVQKG--DEAGGYVKVYTGRKVGLFPTDFLEEI
320 330 340 350 360
411 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 02:55:40 2016 done: Sat Nov 5 02:55:41 2016
Total Scan time: 11.420 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]