Result of FASTA (omim) for
pFN21AE4117
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4117, 494 aa
1>>>pF1KE4117 494 - 494 aa - 494 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9900+/-0.000471; mu= 9.6915+/- 0.029
mean_var=137.4243+/-29.098, 0's: 0 Z-trim(113.6): 163 B-trim: 577 in 1/50
Lambda= 0.109406
statistics sampled from 22758 (22979) to 22758 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.269), width: 16
Scan time: 10.000
The best scores are: opt bits E(85289)
NP_116289 (OMIM: 611587) rho GTPase-activating pro ( 494) 3227 521.6 2e-147
NP_001243352 (OMIM: 611587) rho GTPase-activating ( 485) 3109 503.0 8e-142
NP_001191229 (OMIM: 611587) rho GTPase-activating ( 465) 1844 303.3 9.9e-82
XP_016882351 (OMIM: 609694) PREDICTED: GEM-interac ( 835) 292 58.5 8.5e-08
XP_011526350 (OMIM: 609694) PREDICTED: GEM-interac ( 849) 292 58.5 8.6e-08
XP_016882350 (OMIM: 609694) PREDICTED: GEM-interac ( 884) 292 58.5 8.9e-08
NP_001275927 (OMIM: 609694) GEM-interacting protei ( 941) 292 58.6 9.4e-08
NP_001275928 (OMIM: 609694) GEM-interacting protei ( 944) 292 58.6 9.4e-08
XP_005259984 (OMIM: 609694) PREDICTED: GEM-interac ( 967) 292 58.6 9.5e-08
NP_057657 (OMIM: 609694) GEM-interacting protein i ( 970) 292 58.6 9.6e-08
XP_005267270 (OMIM: 613351) PREDICTED: rho GTPase- ( 585) 208 45.1 0.00064
XP_016866983 (OMIM: 613351) PREDICTED: rho GTPase- ( 635) 208 45.2 0.00068
NP_006116 (OMIM: 300118) rho GTPase-activating pro ( 765) 202 44.3 0.0015
NP_038267 (OMIM: 300118) rho GTPase-activating pro ( 771) 202 44.3 0.0015
NP_001274171 (OMIM: 300118) rho GTPase-activating ( 794) 202 44.3 0.0016
NP_038286 (OMIM: 300118) rho GTPase-activating pro ( 974) 202 44.4 0.0018
NP_277050 (OMIM: 613351) rho GTPase-activating pro ( 663) 197 43.4 0.0023
XP_016873209 (OMIM: 602732) PREDICTED: rho GTPase- ( 395) 193 42.6 0.0024
XP_005267269 (OMIM: 613351) PREDICTED: rho GTPase- ( 713) 197 43.5 0.0025
XP_011518397 (OMIM: 602732) PREDICTED: rho GTPase- ( 439) 193 42.7 0.0026
NP_004299 (OMIM: 602732) rho GTPase-activating pro ( 439) 193 42.7 0.0026
NP_060249 (OMIM: 612002) DEP domain-containing pro ( 527) 187 41.8 0.0059
NP_443083 (OMIM: 609866) stAR-related lipid transf ( 995) 189 42.3 0.0076
XP_016876324 (OMIM: 609866) PREDICTED: stAR-relate (1078) 189 42.3 0.0081
NP_001230405 (OMIM: 609866) stAR-related lipid tra (1078) 189 42.3 0.0081
XP_011533601 (OMIM: 609866) PREDICTED: stAR-relate (1078) 189 42.3 0.0081
NP_001107592 (OMIM: 612002) DEP domain-containing ( 811) 187 41.9 0.0081
XP_016876323 (OMIM: 609866) PREDICTED: stAR-relate (1098) 189 42.4 0.0082
NP_821075 (OMIM: 609866) stAR-related lipid transf (1105) 189 42.4 0.0083
NP_821074 (OMIM: 609866) stAR-related lipid transf (1113) 189 42.4 0.0083
>>NP_116289 (OMIM: 611587) rho GTPase-activating protein (494 aa)
initn: 3227 init1: 3227 opt: 3227 Z-score: 2767.7 bits: 521.6 E(85289): 2e-147
Smith-Waterman score: 3227; 99.6% identity (100.0% similar) in 494 aa overlap (1-494:1-494)
10 20 30 40 50 60
pF1KE4 MATEAQSEGEVPARESGRSDAICSFVICNDSSLRGQPIIFNPDFFVEKLRHEKPEIFTEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MATEAQSEGEVPARESGRSDAICSFVICNDSSLRGQPIIFNPDFFVEKLRHEKPEIFTEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VVSNITRLIDLPGTELAQLMGEVDLKLPGGAGPASGFFRSLMSLKRKEKGVIFGSPLTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 VVSNITRLIDLPGTELAQLMGEVDLKLPGGAGPASGFFRSLMSLKRKEKGVIFGSPLTEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 GIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVATLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 GIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVATLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 KMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 KMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 NLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENITKLNSGMAFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 NLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENITKLNSGMAFM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 IKHSQKLFKAPAYIRECARLHYLGSRTQASKDDLDLIASCHTKSFQLAKSQKRNRVDSCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 IKHSQKLFKAPAYIRECARLHYLGSRTQASKDDLDLIASCHTKSFQLAKSQKRNRVDSCP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 HQEETQHHTEEALRELFQHVHDMPESAKKKQLIRQFNKQSLTQTPGREPSTSQVQKRARS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 HQEETQHHTEEALRELFQHVHDMPESAKKKQLIRQFNKQSLTQTPGREPSTSQVQKRARS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 RSFSGLIKRKVLGNQMMSEKKKKNPTPESVAIGELKGTSKENRNLLFSGSPAVTMTPTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 RSFSGLIKRKVLGNQMMSEKKKKNPTPESVAIGELKGTSKENRNLLFSGSPAVTMTPTRL
430 440 450 460 470 480
490
pF1KE4 KWSEGKKEGKKAFV
:::::::::::.:.
NP_116 KWSEGKKEGKKGFL
490
>>NP_001243352 (OMIM: 611587) rho GTPase-activating prot (485 aa)
initn: 3109 init1: 3109 opt: 3109 Z-score: 2667.2 bits: 503.0 E(85289): 8e-142
Smith-Waterman score: 3109; 99.6% identity (100.0% similar) in 475 aa overlap (20-494:11-485)
10 20 30 40 50 60
pF1KE4 MATEAQSEGEVPARESGRSDAICSFVICNDSSLRGQPIIFNPDFFVEKLRHEKPEIFTEL
:::::::::::::::::::::::::::::::::::::::::
NP_001 MPHQKLSALIDAICSFVICNDSSLRGQPIIFNPDFFVEKLRHEKPEIFTEL
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 VVSNITRLIDLPGTELAQLMGEVDLKLPGGAGPASGFFRSLMSLKRKEKGVIFGSPLTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVSNITRLIDLPGTELAQLMGEVDLKLPGGAGPASGFFRSLMSLKRKEKGVIFGSPLTEE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 GIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVATLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVATLL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 KMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 NLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENITKLNSGMAFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENITKLNSGMAFM
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE4 IKHSQKLFKAPAYIRECARLHYLGSRTQASKDDLDLIASCHTKSFQLAKSQKRNRVDSCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKHSQKLFKAPAYIRECARLHYLGSRTQASKDDLDLIASCHTKSFQLAKSQKRNRVDSCP
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE4 HQEETQHHTEEALRELFQHVHDMPESAKKKQLIRQFNKQSLTQTPGREPSTSQVQKRARS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQEETQHHTEEALRELFQHVHDMPESAKKKQLIRQFNKQSLTQTPGREPSTSQVQKRARS
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE4 RSFSGLIKRKVLGNQMMSEKKKKNPTPESVAIGELKGTSKENRNLLFSGSPAVTMTPTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSFSGLIKRKVLGNQMMSEKKKKNPTPESVAIGELKGTSKENRNLLFSGSPAVTMTPTRL
420 430 440 450 460 470
490
pF1KE4 KWSEGKKEGKKAFV
:::::::::::.:.
NP_001 KWSEGKKEGKKGFL
480
>>NP_001191229 (OMIM: 611587) rho GTPase-activating prot (465 aa)
initn: 3036 init1: 1844 opt: 1844 Z-score: 1588.3 bits: 303.3 E(85289): 9.9e-82
Smith-Waterman score: 2978; 93.7% identity (94.1% similar) in 494 aa overlap (1-494:1-465)
10 20 30 40 50 60
pF1KE4 MATEAQSEGEVPARESGRSDAICSFVICNDSSLRGQPIIFNPDFFVEKLRHEKPEIFTEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MATEAQSEGEVPARESGRSDAICSFVICNDSSLRGQPIIFNPDFFVEKLRHEKPEIFTEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VVSNITRLIDLPGTELAQLMGEVDLKLPGGAGPASGFFRSLMSLKRKEKGVIFGSPLTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVSNITRLIDLPGTELAQLMGEVDLKLPGGAGPASGFFRSLMSLKRKEKGVIFGSPLTEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 GIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVATLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVATLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 KMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 NLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENITKLNSGMAFM
::::::::::::::::::::::::::::::::::::::::
NP_001 NLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWPKN--------------------
250 260 270 280
310 320 330 340 350 360
pF1KE4 IKHSQKLFKAPAYIRECARLHYLGSRTQASKDDLDLIASCHTKSFQLAKSQKRNRVDSCP
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ---------APAYIRECARLHYLGSRTQASKDDLDLIASCHTKSFQLAKSQKRNRVDSCP
290 300 310 320 330
370 380 390 400 410 420
pF1KE4 HQEETQHHTEEALRELFQHVHDMPESAKKKQLIRQFNKQSLTQTPGREPSTSQVQKRARS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQEETQHHTEEALRELFQHVHDMPESAKKKQLIRQFNKQSLTQTPGREPSTSQVQKRARS
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE4 RSFSGLIKRKVLGNQMMSEKKKKNPTPESVAIGELKGTSKENRNLLFSGSPAVTMTPTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSFSGLIKRKVLGNQMMSEKKKKNPTPESVAIGELKGTSKENRNLLFSGSPAVTMTPTRL
400 410 420 430 440 450
490
pF1KE4 KWSEGKKEGKKAFV
:::::::::::.:.
NP_001 KWSEGKKEGKKGFL
460
>>XP_016882351 (OMIM: 609694) PREDICTED: GEM-interacting (835 aa)
initn: 278 init1: 204 opt: 292 Z-score: 260.9 bits: 58.5 E(85289): 8.5e-08
Smith-Waterman score: 292; 32.8% identity (62.4% similar) in 186 aa overlap (130-308:574-757)
100 110 120 130 140 150
pF1KE4 SLMSLKRKEKGVIFGSPLTEEGIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQILRDALN
: :. : :.:..:: :. :: . : .:..
XP_016 ARTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFE
550 560 570 580 590 600
160 170 180 190 200 210
pF1KE4 NGTDIDLESGEFHSNDVATLLKMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIP
:: . ::. .::...:: :: :: ::.. . ..: ...: .. : :. . :
XP_016 NGRALVELSGN-SPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLH-ADPGDDPGTP
610 620 630 640 650 660
220 230 240 250 260 270
pF1KE4 DKDRQ-IEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWP
. . . :..:. :.. :: : : :. :. :...: . .::::: ::...:.: .: :
XP_016 SPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRP
670 680 690 700 710 720
280 290 300 310 320 330
pF1KE4 KNVTANDLQENITKL-NSG-----MAFMIKHSQKLFKAPAYIRECARLHYLGSRTQASKD
. .: : .:: . :.: : ...:
XP_016 PDGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSSPAPGPLT
730 740 750 760 770 780
340 350 360 370 380 390
pF1KE4 DLDLIASCHTKSFQLAKSQKRNRVDSCPHQEETQHHTEEALRELFQHVHDMPESAKKKQL
XP_016 TSSQPPPPHLDPDSQPPVLASDPGPDPQHHSTLEQHPTATPTEVGVRWRDLCSP
790 800 810 820 830
>>XP_011526350 (OMIM: 609694) PREDICTED: GEM-interacting (849 aa)
initn: 278 init1: 204 opt: 292 Z-score: 260.8 bits: 58.5 E(85289): 8.6e-08
Smith-Waterman score: 292; 32.8% identity (62.4% similar) in 186 aa overlap (130-308:453-636)
100 110 120 130 140 150
pF1KE4 SLMSLKRKEKGVIFGSPLTEEGIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQILRDALN
: :. : :.:..:: :. :: . : .:..
XP_011 ARTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFE
430 440 450 460 470 480
160 170 180 190 200 210
pF1KE4 NGTDIDLESGEFHSNDVATLLKMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIP
:: . ::. .::...:: :: :: ::.. . ..: ...: .. : :. . :
XP_011 NGRALVELSGN-SPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLH-ADPGDDPGTP
490 500 510 520 530 540
220 230 240 250 260 270
pF1KE4 DKDRQ-IEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWP
. . . :..:. :.. :: : : :. :. :...: . .::::: ::...:.: .: :
XP_011 SPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRP
550 560 570 580 590 600
280 290 300 310 320 330
pF1KE4 KNVTANDLQENITKL-NSG-----MAFMIKHSQKLFKAPAYIRECARLHYLGSRTQASKD
. .: : .:: . :.: : ...:
XP_011 PDGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSSPAPGPLT
610 620 630 640 650 660
340 350 360 370 380 390
pF1KE4 DLDLIASCHTKSFQLAKSQKRNRVDSCPHQEETQHHTEEALRELFQHVHDMPESAKKKQL
XP_011 TSSQPPPPHLDPDSQPPVLASDPGPDPQHHSTLEQHPTATPTEIPTPQSDQREDVAEDTK
670 680 690 700 710 720
>>XP_016882350 (OMIM: 609694) PREDICTED: GEM-interacting (884 aa)
initn: 278 init1: 204 opt: 292 Z-score: 260.6 bits: 58.5 E(85289): 8.9e-08
Smith-Waterman score: 292; 32.8% identity (62.4% similar) in 186 aa overlap (130-308:574-757)
100 110 120 130 140 150
pF1KE4 SLMSLKRKEKGVIFGSPLTEEGIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQILRDALN
: :. : :.:..:: :. :: . : .:..
XP_016 ARTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFE
550 560 570 580 590 600
160 170 180 190 200 210
pF1KE4 NGTDIDLESGEFHSNDVATLLKMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIP
:: . ::. .::...:: :: :: ::.. . ..: ...: .. : :. . :
XP_016 NGRALVELSGN-SPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLH-ADPGDDPGTP
610 620 630 640 650 660
220 230 240 250 260 270
pF1KE4 DKDRQ-IEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWP
. . . :..:. :.. :: : : :. :. :...: . .::::: ::...:.: .: :
XP_016 SPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRP
670 680 690 700 710 720
280 290 300 310 320 330
pF1KE4 KNVTANDLQENITKL-NSG-----MAFMIKHSQKLFKAPAYIRECARLHYLGSRTQASKD
. .: : .:: . :.: : ...:
XP_016 PDGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSSPAPGPLT
730 740 750 760 770 780
340 350 360 370 380 390
pF1KE4 DLDLIASCHTKSFQLAKSQKRNRVDSCPHQEETQHHTEEALRELFQHVHDMPESAKKKQL
XP_016 TSSQPPPPHLDPDSQPPVLASDPGPDPQHHSTLEQHPTATPTEIPTPQSDQREDVAEDTK
790 800 810 820 830 840
>>NP_001275927 (OMIM: 609694) GEM-interacting protein is (941 aa)
initn: 278 init1: 204 opt: 292 Z-score: 260.2 bits: 58.6 E(85289): 9.4e-08
Smith-Waterman score: 292; 32.8% identity (62.4% similar) in 186 aa overlap (130-308:545-728)
100 110 120 130 140 150
pF1KE4 SLMSLKRKEKGVIFGSPLTEEGIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQILRDALN
: :. : :.:..:: :. :: . : .:..
NP_001 ARTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFE
520 530 540 550 560 570
160 170 180 190 200 210
pF1KE4 NGTDIDLESGEFHSNDVATLLKMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIP
:: . ::. .::...:: :: :: ::.. . ..: ...: .. : :. . :
NP_001 NGRALVELSGN-SPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLH-ADPGDDPGTP
580 590 600 610 620 630
220 230 240 250 260 270
pF1KE4 DKDRQ-IEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWP
. . . :..:. :.. :: : : :. :. :...: . .::::: ::...:.: .: :
NP_001 SPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRP
640 650 660 670 680 690
280 290 300 310 320 330
pF1KE4 KNVTANDLQENITKL-NSG-----MAFMIKHSQKLFKAPAYIRECARLHYLGSRTQASKD
. .: : .:: . :.: : ...:
NP_001 PDGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSSPAPGPLT
700 710 720 730 740 750
340 350 360 370 380 390
pF1KE4 DLDLIASCHTKSFQLAKSQKRNRVDSCPHQEETQHHTEEALRELFQHVHDMPESAKKKQL
NP_001 TSSQPPPPHLDPDSQPPVLASDPGPDPQHHSTLEQHPTATPTEIPTPQSDQREDVAEDTK
760 770 780 790 800 810
>>NP_001275928 (OMIM: 609694) GEM-interacting protein is (944 aa)
initn: 278 init1: 204 opt: 292 Z-score: 260.2 bits: 58.6 E(85289): 9.4e-08
Smith-Waterman score: 292; 32.8% identity (62.4% similar) in 186 aa overlap (130-308:548-731)
100 110 120 130 140 150
pF1KE4 SLMSLKRKEKGVIFGSPLTEEGIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQILRDALN
: :. : :.:..:: :. :: . : .:..
NP_001 ARTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFE
520 530 540 550 560 570
160 170 180 190 200 210
pF1KE4 NGTDIDLESGEFHSNDVATLLKMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIP
:: . ::. .::...:: :: :: ::.. . ..: ...: .. : :. . :
NP_001 NGRALVELSGN-SPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLH-ADPGDDPGTP
580 590 600 610 620 630
220 230 240 250 260 270
pF1KE4 DKDRQ-IEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWP
. . . :..:. :.. :: : : :. :. :...: . .::::: ::...:.: .: :
NP_001 SPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRP
640 650 660 670 680 690
280 290 300 310 320 330
pF1KE4 KNVTANDLQENITKL-NSG-----MAFMIKHSQKLFKAPAYIRECARLHYLGSRTQASKD
. .: : .:: . :.: : ...:
NP_001 PDGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSSPAPGPLT
700 710 720 730 740 750
340 350 360 370 380 390
pF1KE4 DLDLIASCHTKSFQLAKSQKRNRVDSCPHQEETQHHTEEALRELFQHVHDMPESAKKKQL
NP_001 TSSQPPPPHLDPDSQPPVLASDPGPDPQHHSTLEQHPTATPTEIPTPQSDQREDVAEDTK
760 770 780 790 800 810
>>XP_005259984 (OMIM: 609694) PREDICTED: GEM-interacting (967 aa)
initn: 278 init1: 204 opt: 292 Z-score: 260.1 bits: 58.6 E(85289): 9.5e-08
Smith-Waterman score: 292; 32.8% identity (62.4% similar) in 186 aa overlap (130-308:571-754)
100 110 120 130 140 150
pF1KE4 SLMSLKRKEKGVIFGSPLTEEGIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQILRDALN
: :. : :.:..:: :. :: . : .:..
XP_005 ARTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFE
550 560 570 580 590 600
160 170 180 190 200 210
pF1KE4 NGTDIDLESGEFHSNDVATLLKMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIP
:: . ::. .::...:: :: :: ::.. . ..: ...: .. : :. . :
XP_005 NGRALVELSGN-SPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLH-ADPGDDPGTP
610 620 630 640 650
220 230 240 250 260 270
pF1KE4 DKDRQ-IEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWP
. . . :..:. :.. :: : : :. :. :...: . .::::: ::...:.: .: :
XP_005 SPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRP
660 670 680 690 700 710
280 290 300 310 320 330
pF1KE4 KNVTANDLQENITKL-NSG-----MAFMIKHSQKLFKAPAYIRECARLHYLGSRTQASKD
. .: : .:: . :.: : ...:
XP_005 PDGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSSPAPGPLT
720 730 740 750 760 770
340 350 360 370 380 390
pF1KE4 DLDLIASCHTKSFQLAKSQKRNRVDSCPHQEETQHHTEEALRELFQHVHDMPESAKKKQL
XP_005 TSSQPPPPHLDPDSQPPVLASDPGPDPQHHSTLEQHPTATPTEIPTPQSDQREDVAEDTK
780 790 800 810 820 830
>>NP_057657 (OMIM: 609694) GEM-interacting protein isofo (970 aa)
initn: 278 init1: 204 opt: 292 Z-score: 260.0 bits: 58.6 E(85289): 9.6e-08
Smith-Waterman score: 292; 32.8% identity (62.4% similar) in 186 aa overlap (130-308:574-757)
100 110 120 130 140 150
pF1KE4 SLMSLKRKEKGVIFGSPLTEEGIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQILRDALN
: :. : :.:..:: :. :: . : .:..
NP_057 ARTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFE
550 560 570 580 590 600
160 170 180 190 200 210
pF1KE4 NGTDIDLESGEFHSNDVATLLKMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIP
:: . ::. .::...:: :: :: ::.. . ..: ...: .. : :. . :
NP_057 NGRALVELSGN-SPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLH-ADPGDDPGTP
610 620 630 640 650 660
220 230 240 250 260 270
pF1KE4 DKDRQ-IEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWP
. . . :..:. :.. :: : : :. :. :...: . .::::: ::...:.: .: :
NP_057 SPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRP
670 680 690 700 710 720
280 290 300 310 320 330
pF1KE4 KNVTANDLQENITKL-NSG-----MAFMIKHSQKLFKAPAYIRECARLHYLGSRTQASKD
. .: : .:: . :.: : ...:
NP_057 PDGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSSPAPGPLT
730 740 750 760 770 780
340 350 360 370 380 390
pF1KE4 DLDLIASCHTKSFQLAKSQKRNRVDSCPHQEETQHHTEEALRELFQHVHDMPESAKKKQL
NP_057 TSSQPPPPHLDPDSQPPVLASDPGPDPQHHSTLEQHPTATPTEIPTPQSDQREDVAEDTK
790 800 810 820 830 840
494 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 01:53:28 2016 done: Sun Nov 6 01:53:29 2016
Total Scan time: 10.000 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]