Result of FASTA (omim) for
pFN21AE0630
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0630, 371 aa
1>>>pF1KE0630 371 - 371 aa - 371 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.7519+/-0.000288; mu= 6.9879+/- 0.018
mean_var=165.3640+/-34.100, 0's: 0 Z-trim(123.2): 16 B-trim: 2518 in 1/57
Lambda= 0.099736
statistics sampled from 42478 (42505) to 42478 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.803), E-opt: 0.2 (0.498), width: 16
Scan time: 9.160
The best scores are: opt bits E(85289)
NP_751907 (OMIM: 611256) NADPH oxidase organizer 1 ( 371) 2548 377.9 2e-104
NP_653204 (OMIM: 611256) NADPH oxidase organizer 1 ( 370) 2530 375.3 1.2e-103
NP_751908 (OMIM: 611256) NADPH oxidase organizer 1 ( 376) 2528 375.1 1.5e-103
XP_005255156 (OMIM: 611256) PREDICTED: NADPH oxida ( 376) 2528 375.1 1.5e-103
XP_016878416 (OMIM: 611256) PREDICTED: NADPH oxida ( 376) 2528 375.1 1.5e-103
XP_016878417 (OMIM: 611256) PREDICTED: NADPH oxida ( 376) 2528 375.1 1.5e-103
NP_001254650 (OMIM: 611256) NADPH oxidase organize ( 375) 2510 372.5 8.9e-103
>>NP_751907 (OMIM: 611256) NADPH oxidase organizer 1 iso (371 aa)
initn: 2548 init1: 2548 opt: 2548 Z-score: 1995.8 bits: 377.9 E(85289): 2e-104
Smith-Waterman score: 2548; 100.0% identity (100.0% similar) in 371 aa overlap (1-371:1-371)
10 20 30 40 50 60
pF1KE0 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GLLRRSDRVLPKLLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTITGFFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 GLLRRSDRVLPKLLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTITGFFA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 PQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTRDRPFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 PQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTRDRPFQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 AQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGPQFCAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 AQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGPQFCAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 RAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALLSGTGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 RAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALLSGTGF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 RGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQGRPRGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 RGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQGRPRGC
310 320 330 340 350 360
370
pF1KE0 VDSVPHPTTEQ
:::::::::::
NP_751 VDSVPHPTTEQ
370
>>NP_653204 (OMIM: 611256) NADPH oxidase organizer 1 iso (370 aa)
initn: 2215 init1: 2215 opt: 2530 Z-score: 1981.8 bits: 375.3 E(85289): 1.2e-103
Smith-Waterman score: 2530; 99.7% identity (99.7% similar) in 371 aa overlap (1-371:1-370)
10 20 30 40 50 60
pF1KE0 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
NP_653 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLK-TLKETFPVEA
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 GLLRRSDRVLPKLLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTITGFFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 GLLRRSDRVLPKLLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTITGFFA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 PQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTRDRPFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 PQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTRDRPFQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 AQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGPQFCAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 AQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGPQFCAS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 RAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALLSGTGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 RAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALLSGTGF
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE0 RGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQGRPRGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 RGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQGRPRGC
300 310 320 330 340 350
370
pF1KE0 VDSVPHPTTEQ
:::::::::::
NP_653 VDSVPHPTTEQ
360 370
>>NP_751908 (OMIM: 611256) NADPH oxidase organizer 1 iso (376 aa)
initn: 2065 init1: 2065 opt: 2528 Z-score: 1980.1 bits: 375.1 E(85289): 1.5e-103
Smith-Waterman score: 2528; 98.7% identity (98.7% similar) in 376 aa overlap (1-371:1-376)
10 20 30 40 50 60
pF1KE0 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 GLLRRSDRVLPKLL-----DAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::
NP_751 GLLRRSDRVLPKLLGQASLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE0 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE0 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG
310 320 330 340 350 360
360 370
pF1KE0 RPRGCVDSVPHPTTEQ
::::::::::::::::
NP_751 RPRGCVDSVPHPTTEQ
370
>>XP_005255156 (OMIM: 611256) PREDICTED: NADPH oxidase o (376 aa)
initn: 2065 init1: 2065 opt: 2528 Z-score: 1980.1 bits: 375.1 E(85289): 1.5e-103
Smith-Waterman score: 2528; 98.7% identity (98.7% similar) in 376 aa overlap (1-371:1-376)
10 20 30 40 50 60
pF1KE0 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 GLLRRSDRVLPKLL-----DAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_005 GLLRRSDRVLPKLLGQASLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE0 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE0 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG
310 320 330 340 350 360
360 370
pF1KE0 RPRGCVDSVPHPTTEQ
::::::::::::::::
XP_005 RPRGCVDSVPHPTTEQ
370
>>XP_016878416 (OMIM: 611256) PREDICTED: NADPH oxidase o (376 aa)
initn: 2065 init1: 2065 opt: 2528 Z-score: 1980.1 bits: 375.1 E(85289): 1.5e-103
Smith-Waterman score: 2528; 98.7% identity (98.7% similar) in 376 aa overlap (1-371:1-376)
10 20 30 40 50 60
pF1KE0 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 GLLRRSDRVLPKLL-----DAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_016 GLLRRSDRVLPKLLGQASLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE0 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE0 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG
310 320 330 340 350 360
360 370
pF1KE0 RPRGCVDSVPHPTTEQ
::::::::::::::::
XP_016 RPRGCVDSVPHPTTEQ
370
>>XP_016878417 (OMIM: 611256) PREDICTED: NADPH oxidase o (376 aa)
initn: 2065 init1: 2065 opt: 2528 Z-score: 1980.1 bits: 375.1 E(85289): 1.5e-103
Smith-Waterman score: 2528; 98.7% identity (98.7% similar) in 376 aa overlap (1-371:1-376)
10 20 30 40 50 60
pF1KE0 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 GLLRRSDRVLPKLL-----DAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_016 GLLRRSDRVLPKLLGQASLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE0 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE0 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG
310 320 330 340 350 360
360 370
pF1KE0 RPRGCVDSVPHPTTEQ
::::::::::::::::
XP_016 RPRGCVDSVPHPTTEQ
370
>>NP_001254650 (OMIM: 611256) NADPH oxidase organizer 1 (375 aa)
initn: 2384 init1: 2065 opt: 2510 Z-score: 1966.1 bits: 372.5 E(85289): 8.9e-103
Smith-Waterman score: 2510; 98.4% identity (98.4% similar) in 376 aa overlap (1-371:1-375)
10 20 30 40 50 60
pF1KE0 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEA
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
NP_001 MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLK-TLKETFPVEA
10 20 30 40 50
70 80 90 100 110
pF1KE0 GLLRRSDRVLPKLL-----DAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::
NP_001 GLLRRSDRVLPKLLGQASLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGFFAPQPLDLEPALPPGSRVILPTPEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGGPSLGSSGP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRPEGLGALL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGTGFRGGDDPAGEARGFPEPSQATAPPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQG
300 310 320 330 340 350
360 370
pF1KE0 RPRGCVDSVPHPTTEQ
::::::::::::::::
NP_001 RPRGCVDSVPHPTTEQ
360 370
371 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 19:35:32 2016 done: Wed Nov 2 19:35:33 2016
Total Scan time: 9.160 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]