Result of FASTA (omim) for
pFN21AE4121
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4121, 505 aa
1>>>pF1KE4121 505 - 505 aa - 505 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2429+/-0.000344; mu= 14.8349+/- 0.021
mean_var=103.2246+/-21.414, 0's: 0 Z-trim(116.7): 101 B-trim: 1218 in 2/52
Lambda= 0.126236
statistics sampled from 28042 (28156) to 28042 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.33), width: 16
Scan time: 9.200
The best scores are: opt bits E(85289)
NP_001273990 (OMIM: 609700) rab5 GDP/GTP exchange ( 505) 3378 625.8 8.9e-179
NP_001273991 (OMIM: 609700) rab5 GDP/GTP exchange ( 491) 3291 610.0 5.1e-174
NP_055319 (OMIM: 609700) rab5 GDP/GTP exchange fac ( 491) 3291 610.0 5.1e-174
NP_001273989 (OMIM: 609700) rab5 GDP/GTP exchange ( 299) 2013 377.1 4e-104
NP_001317706 (OMIM: 611714) GTPase-activating prot (1412) 290 63.7 3.9e-09
XP_005251961 (OMIM: 611714) PREDICTED: GTPase-acti (1433) 290 63.7 4e-09
XP_016870098 (OMIM: 611714) PREDICTED: GTPase-acti (1433) 290 63.7 4e-09
NP_001317707 (OMIM: 611714) GTPase-activating prot (1433) 290 63.7 4e-09
XP_016870096 (OMIM: 611714) PREDICTED: GTPase-acti (1439) 290 63.7 4e-09
XP_006717107 (OMIM: 611714) PREDICTED: GTPase-acti (1439) 290 63.7 4e-09
XP_016870095 (OMIM: 611714) PREDICTED: GTPase-acti (1439) 290 63.7 4e-09
XP_016870097 (OMIM: 611714) PREDICTED: GTPase-acti (1439) 290 63.7 4e-09
NP_001269610 (OMIM: 611714) GTPase-activating prot (1439) 290 63.7 4e-09
XP_016870092 (OMIM: 611714) PREDICTED: GTPase-acti (1460) 290 63.8 4e-09
XP_016870094 (OMIM: 611714) PREDICTED: GTPase-acti (1460) 290 63.8 4e-09
XP_016870091 (OMIM: 611714) PREDICTED: GTPase-acti (1460) 290 63.8 4e-09
XP_016870090 (OMIM: 611714) PREDICTED: GTPase-acti (1460) 290 63.8 4e-09
XP_011516809 (OMIM: 611714) PREDICTED: GTPase-acti (1460) 290 63.8 4e-09
NP_001269609 (OMIM: 611714) GTPase-activating prot (1460) 290 63.8 4e-09
XP_005251958 (OMIM: 611714) PREDICTED: GTPase-acti (1460) 290 63.8 4e-09
XP_016870093 (OMIM: 611714) PREDICTED: GTPase-acti (1460) 290 63.8 4e-09
XP_011516808 (OMIM: 611714) PREDICTED: GTPase-acti (1466) 290 63.8 4.1e-09
NP_001269608 (OMIM: 611714) GTPase-activating prot (1478) 290 63.8 4.1e-09
NP_056450 (OMIM: 611714) GTPase-activating protein (1487) 290 63.8 4.1e-09
XP_011516804 (OMIM: 611714) PREDICTED: GTPase-acti (1487) 290 63.8 4.1e-09
XP_016870089 (OMIM: 611714) PREDICTED: GTPase-acti (1487) 290 63.8 4.1e-09
XP_011516802 (OMIM: 611714) PREDICTED: GTPase-acti (1487) 290 63.8 4.1e-09
XP_011516801 (OMIM: 611714) PREDICTED: GTPase-acti (1487) 290 63.8 4.1e-09
XP_011535467 (OMIM: 610223) PREDICTED: ras and Rab ( 648) 212 49.3 4e-05
XP_011535466 (OMIM: 610223) PREDICTED: ras and Rab ( 909) 212 49.4 5.3e-05
NP_001306916 (OMIM: 610223) ras and Rab interactor ( 910) 212 49.4 5.3e-05
XP_016877140 (OMIM: 610223) PREDICTED: ras and Rab ( 954) 212 49.4 5.5e-05
NP_079108 (OMIM: 610223) ras and Rab interactor 3 ( 985) 212 49.4 5.6e-05
XP_016877143 (OMIM: 610223) PREDICTED: ras and Rab ( 883) 209 48.8 7.5e-05
XP_016877142 (OMIM: 610223) PREDICTED: ras and Rab ( 888) 209 48.8 7.5e-05
XP_005260790 (OMIM: 610222,613075) PREDICTED: ras ( 689) 199 46.9 0.00022
XP_011527561 (OMIM: 610222,613075) PREDICTED: ras ( 842) 199 47.0 0.00026
XP_016883381 (OMIM: 610222,613075) PREDICTED: ras ( 842) 199 47.0 0.00026
XP_016883380 (OMIM: 610222,613075) PREDICTED: ras ( 850) 199 47.0 0.00026
XP_006723640 (OMIM: 610222,613075) PREDICTED: ras ( 895) 199 47.0 0.00027
XP_011527560 (OMIM: 610222,613075) PREDICTED: ras ( 895) 199 47.0 0.00027
XP_006723637 (OMIM: 610222,613075) PREDICTED: ras ( 895) 199 47.0 0.00027
XP_011527559 (OMIM: 610222,613075) PREDICTED: ras ( 895) 199 47.0 0.00027
XP_005260788 (OMIM: 610222,613075) PREDICTED: ras ( 895) 199 47.0 0.00027
XP_016883379 (OMIM: 610222,613075) PREDICTED: ras ( 895) 199 47.0 0.00027
XP_006723638 (OMIM: 610222,613075) PREDICTED: ras ( 895) 199 47.0 0.00027
NP_061866 (OMIM: 610222,613075) ras and Rab intera ( 895) 199 47.0 0.00027
XP_016883378 (OMIM: 610222,613075) PREDICTED: ras ( 925) 199 47.0 0.00028
XP_016883377 (OMIM: 610222,613075) PREDICTED: ras ( 944) 199 47.0 0.00028
NP_001229510 (OMIM: 610222,613075) ras and Rab int ( 944) 199 47.0 0.00028
>>NP_001273990 (OMIM: 609700) rab5 GDP/GTP exchange fact (505 aa)
initn: 3378 init1: 3378 opt: 3378 Z-score: 3330.6 bits: 625.8 E(85289): 8.9e-179
Smith-Waterman score: 3378; 100.0% identity (100.0% similar) in 505 aa overlap (1-505:1-505)
10 20 30 40 50 60
pF1KE4 MMASSYHEVVSRKKMSLKSERRGIHVDQSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMASSYHEVVSRKKMSLKSERRGIHVDQSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 MHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ETTDDEKKDLAIQKRIRALRWVTPQMLCVPVNEDIPEVSDMVVKAITDIIEMDSKRVPRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETTDDEKKDLAIQKRIRALRWVTPQMLCVPVNEDIPEVSDMVVKAITDIIEMDSKRVPRD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 KLACITKCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLACITKCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 LMTGEDGYYFTNLCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPDACLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMTGEDGYYFTNLCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPDACLG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 VKQMYKNLDLLSQLNERQERIMNEAKKLEKDLIDWTDGIAREVQDIVEKYPLEIKPPNQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKQMYKNLDLLSQLNERQERIMNEAKKLEKDLIDWTDGIAREVQDIVEKYPLEIKPPNQP
430 440 450 460 470 480
490 500
pF1KE4 LAAIDSENVENDKLPPPLQPQVYAG
:::::::::::::::::::::::::
NP_001 LAAIDSENVENDKLPPPLQPQVYAG
490 500
>>NP_001273991 (OMIM: 609700) rab5 GDP/GTP exchange fact (491 aa)
initn: 3291 init1: 3291 opt: 3291 Z-score: 3245.2 bits: 610.0 E(85289): 5.1e-174
Smith-Waterman score: 3291; 100.0% identity (100.0% similar) in 491 aa overlap (15-505:1-491)
10 20 30 40 50 60
pF1KE4 MMASSYHEVVSRKKMSLKSERRGIHVDQSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKA
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSLKSERRGIHVDQSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKA
10 20 30 40
70 80 90 100 110 120
pF1KE4 RQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE4 ASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEG
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE4 MHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCP
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE4 ETTDDEKKDLAIQKRIRALRWVTPQMLCVPVNEDIPEVSDMVVKAITDIIEMDSKRVPRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETTDDEKKDLAIQKRIRALRWVTPQMLCVPVNEDIPEVSDMVVKAITDIIEMDSKRVPRD
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE4 KLACITKCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLACITKCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSR
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE4 LMTGEDGYYFTNLCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPDACLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMTGEDGYYFTNLCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPDACLG
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE4 VKQMYKNLDLLSQLNERQERIMNEAKKLEKDLIDWTDGIAREVQDIVEKYPLEIKPPNQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKQMYKNLDLLSQLNERQERIMNEAKKLEKDLIDWTDGIAREVQDIVEKYPLEIKPPNQP
410 420 430 440 450 460
490 500
pF1KE4 LAAIDSENVENDKLPPPLQPQVYAG
:::::::::::::::::::::::::
NP_001 LAAIDSENVENDKLPPPLQPQVYAG
470 480 490
>>NP_055319 (OMIM: 609700) rab5 GDP/GTP exchange factor (491 aa)
initn: 3291 init1: 3291 opt: 3291 Z-score: 3245.2 bits: 610.0 E(85289): 5.1e-174
Smith-Waterman score: 3291; 100.0% identity (100.0% similar) in 491 aa overlap (15-505:1-491)
10 20 30 40 50 60
pF1KE4 MMASSYHEVVSRKKMSLKSERRGIHVDQSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKA
::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MSLKSERRGIHVDQSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKA
10 20 30 40
70 80 90 100 110 120
pF1KE4 RQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE4 ASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEG
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE4 MHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCP
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE4 ETTDDEKKDLAIQKRIRALRWVTPQMLCVPVNEDIPEVSDMVVKAITDIIEMDSKRVPRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ETTDDEKKDLAIQKRIRALRWVTPQMLCVPVNEDIPEVSDMVVKAITDIIEMDSKRVPRD
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE4 KLACITKCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KLACITKCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSR
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE4 LMTGEDGYYFTNLCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPDACLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LMTGEDGYYFTNLCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPDACLG
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE4 VKQMYKNLDLLSQLNERQERIMNEAKKLEKDLIDWTDGIAREVQDIVEKYPLEIKPPNQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VKQMYKNLDLLSQLNERQERIMNEAKKLEKDLIDWTDGIAREVQDIVEKYPLEIKPPNQP
410 420 430 440 450 460
490 500
pF1KE4 LAAIDSENVENDKLPPPLQPQVYAG
:::::::::::::::::::::::::
NP_055 LAAIDSENVENDKLPPPLQPQVYAG
470 480 490
>>NP_001273989 (OMIM: 609700) rab5 GDP/GTP exchange fact (299 aa)
initn: 2013 init1: 2013 opt: 2013 Z-score: 1990.3 bits: 377.1 E(85289): 4e-104
Smith-Waterman score: 2013; 100.0% identity (100.0% similar) in 299 aa overlap (207-505:1-299)
180 190 200 210 220 230
pF1KE4 FLEGMHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKY
::::::::::::::::::::::::::::::
NP_001 MQTRGKVPPERVEKIMDQIEKYIMTRLYKY
10 20 30
240 250 260 270 280 290
pF1KE4 VFCPETTDDEKKDLAIQKRIRALRWVTPQMLCVPVNEDIPEVSDMVVKAITDIIEMDSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFCPETTDDEKKDLAIQKRIRALRWVTPQMLCVPVNEDIPEVSDMVVKAITDIIEMDSKR
40 50 60 70 80 90
300 310 320 330 340 350
pF1KE4 VPRDKLACITKCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPRDKLACITKCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFC
100 110 120 130 140 150
360 370 380 390 400 410
pF1KE4 NPSRLMTGEDGYYFTNLCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPSRLMTGEDGYYFTNLCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPD
160 170 180 190 200 210
420 430 440 450 460 470
pF1KE4 ACLGVKQMYKNLDLLSQLNERQERIMNEAKKLEKDLIDWTDGIAREVQDIVEKYPLEIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACLGVKQMYKNLDLLSQLNERQERIMNEAKKLEKDLIDWTDGIAREVQDIVEKYPLEIKP
220 230 240 250 260 270
480 490 500
pF1KE4 PNQPLAAIDSENVENDKLPPPLQPQVYAG
:::::::::::::::::::::::::::::
NP_001 PNQPLAAIDSENVENDKLPPPLQPQVYAG
280 290
>>NP_001317706 (OMIM: 611714) GTPase-activating protein (1412 aa)
initn: 221 init1: 130 opt: 290 Z-score: 284.9 bits: 63.7 E(85289): 3.9e-09
Smith-Waterman score: 290; 26.1% identity (64.9% similar) in 222 aa overlap (172-384:1197-1409)
150 160 170 180 190
pF1KE4 NRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEGMHYKRDLSIEEQSECAQDF--
:. . :.. ... . .... ..::
NP_001 RLLQRVLRDKEVANRYFTTVCVRLLLESKEKKIREFIQD--FQKLTAADDKTAQVEDFLQ
1170 1180 1190 1200 1210 1220
200 210 220 230 240 250
pF1KE4 --YHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQKRIR
: .:. . .. . :... . ::. .:.:..: .: :. : .: .....:.
NP_001 FLYGAMAQDVIWQN-ASEEQLQDAQLAIERSVMNRIFKLAFYPNQDGDILRDQVLHEHIQ
1230 1240 1250 1260 1270 1280
260 270 280 290 300 310
pF1KE4 AL-RWVTPQMLCVPVNEDIPEVSDMVV---KAITDIIEMDSKRVPRDKLACITKCSKHIF
: . :: . . .:::: . .: ..: ... ..::::. :: . . :.
NP_001 RLSKVVTANHRAL----QIPEVYLREAPWPSAQSEIRTISAYKTPRDKVQCILRMCSTIM
1290 1300 1310 1320 1330
320 330 340 350 360 370
pF1KE4 NAIKITKNEPA-SADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTN
: ....... . .::::.:.:.....:.::: : :..:::. : . ..::..:.. .
NP_001 NLLSLANEDSVPGADDFVPVLVFVLIKANPPCLLSTVQYISSF--YASCLSGEESYWWMQ
1340 1350 1360 1370 1380 1390
380 390 400 410 420 430
pF1KE4 LCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPDACLGVKQMYKNLDLLS
. :: ::. .:
NP_001 FTAAVEFIKTIDDRK
1400 1410
>>XP_005251961 (OMIM: 611714) PREDICTED: GTPase-activati (1433 aa)
initn: 221 init1: 130 opt: 290 Z-score: 284.8 bits: 63.7 E(85289): 4e-09
Smith-Waterman score: 290; 26.1% identity (64.9% similar) in 222 aa overlap (172-384:1218-1430)
150 160 170 180 190
pF1KE4 NRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEGMHYKRDLSIEEQSECAQDF--
:. . :.. ... . .... ..::
XP_005 RLLQRVLRDKEVANRYFTTVCVRLLLESKEKKIREFIQD--FQKLTAADDKTAQVEDFLQ
1190 1200 1210 1220 1230 1240
200 210 220 230 240 250
pF1KE4 --YHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQKRIR
: .:. . .. . :... . ::. .:.:..: .: :. : .: .....:.
XP_005 FLYGAMAQDVIWQN-ASEEQLQDAQLAIERSVMNRIFKLAFYPNQDGDILRDQVLHEHIQ
1250 1260 1270 1280 1290 1300
260 270 280 290 300 310
pF1KE4 AL-RWVTPQMLCVPVNEDIPEVSDMVV---KAITDIIEMDSKRVPRDKLACITKCSKHIF
: . :: . . .:::: . .: ..: ... ..::::. :: . . :.
XP_005 RLSKVVTANHRAL----QIPEVYLREAPWPSAQSEIRTISAYKTPRDKVQCILRMCSTIM
1310 1320 1330 1340 1350 1360
320 330 340 350 360 370
pF1KE4 NAIKITKNEPA-SADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTN
: ....... . .::::.:.:.....:.::: : :..:::. : . ..::..:.. .
XP_005 NLLSLANEDSVPGADDFVPVLVFVLIKANPPCLLSTVQYISSF--YASCLSGEESYWWMQ
1370 1380 1390 1400 1410
380 390 400 410 420 430
pF1KE4 LCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPDACLGVKQMYKNLDLLS
. :: ::. .:
XP_005 FTAAVEFIKTIDDRK
1420 1430
>>XP_016870098 (OMIM: 611714) PREDICTED: GTPase-activati (1433 aa)
initn: 221 init1: 130 opt: 290 Z-score: 284.8 bits: 63.7 E(85289): 4e-09
Smith-Waterman score: 290; 26.1% identity (64.9% similar) in 222 aa overlap (172-384:1218-1430)
150 160 170 180 190
pF1KE4 NRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEGMHYKRDLSIEEQSECAQDF--
:. . :.. ... . .... ..::
XP_016 RLLQRVLRDKEVANRYFTTVCVRLLLESKEKKIREFIQD--FQKLTAADDKTAQVEDFLQ
1190 1200 1210 1220 1230 1240
200 210 220 230 240 250
pF1KE4 --YHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQKRIR
: .:. . .. . :... . ::. .:.:..: .: :. : .: .....:.
XP_016 FLYGAMAQDVIWQN-ASEEQLQDAQLAIERSVMNRIFKLAFYPNQDGDILRDQVLHEHIQ
1250 1260 1270 1280 1290 1300
260 270 280 290 300 310
pF1KE4 AL-RWVTPQMLCVPVNEDIPEVSDMVV---KAITDIIEMDSKRVPRDKLACITKCSKHIF
: . :: . . .:::: . .: ..: ... ..::::. :: . . :.
XP_016 RLSKVVTANHRAL----QIPEVYLREAPWPSAQSEIRTISAYKTPRDKVQCILRMCSTIM
1310 1320 1330 1340 1350 1360
320 330 340 350 360 370
pF1KE4 NAIKITKNEPA-SADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTN
: ....... . .::::.:.:.....:.::: : :..:::. : . ..::..:.. .
XP_016 NLLSLANEDSVPGADDFVPVLVFVLIKANPPCLLSTVQYISSF--YASCLSGEESYWWMQ
1370 1380 1390 1400 1410
380 390 400 410 420 430
pF1KE4 LCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPDACLGVKQMYKNLDLLS
. :: ::. .:
XP_016 FTAAVEFIKTIDDRK
1420 1430
>>NP_001317707 (OMIM: 611714) GTPase-activating protein (1433 aa)
initn: 221 init1: 130 opt: 290 Z-score: 284.8 bits: 63.7 E(85289): 4e-09
Smith-Waterman score: 290; 26.1% identity (64.9% similar) in 222 aa overlap (172-384:1218-1430)
150 160 170 180 190
pF1KE4 NRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEGMHYKRDLSIEEQSECAQDF--
:. . :.. ... . .... ..::
NP_001 RLLQRVLRDKEVANRYFTTVCVRLLLESKEKKIREFIQD--FQKLTAADDKTAQVEDFLQ
1190 1200 1210 1220 1230 1240
200 210 220 230 240 250
pF1KE4 --YHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQKRIR
: .:. . .. . :... . ::. .:.:..: .: :. : .: .....:.
NP_001 FLYGAMAQDVIWQN-ASEEQLQDAQLAIERSVMNRIFKLAFYPNQDGDILRDQVLHEHIQ
1250 1260 1270 1280 1290 1300
260 270 280 290 300 310
pF1KE4 AL-RWVTPQMLCVPVNEDIPEVSDMVV---KAITDIIEMDSKRVPRDKLACITKCSKHIF
: . :: . . .:::: . .: ..: ... ..::::. :: . . :.
NP_001 RLSKVVTANHRAL----QIPEVYLREAPWPSAQSEIRTISAYKTPRDKVQCILRMCSTIM
1310 1320 1330 1340 1350 1360
320 330 340 350 360 370
pF1KE4 NAIKITKNEPA-SADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTN
: ....... . .::::.:.:.....:.::: : :..:::. : . ..::..:.. .
NP_001 NLLSLANEDSVPGADDFVPVLVFVLIKANPPCLLSTVQYISSF--YASCLSGEESYWWMQ
1370 1380 1390 1400 1410
380 390 400 410 420 430
pF1KE4 LCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPDACLGVKQMYKNLDLLS
. :: ::. .:
NP_001 FTAAVEFIKTIDDRK
1420 1430
>>XP_016870096 (OMIM: 611714) PREDICTED: GTPase-activati (1439 aa)
initn: 221 init1: 130 opt: 290 Z-score: 284.8 bits: 63.7 E(85289): 4e-09
Smith-Waterman score: 290; 26.1% identity (64.9% similar) in 222 aa overlap (172-384:1224-1436)
150 160 170 180 190
pF1KE4 NRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEGMHYKRDLSIEEQSECAQDF--
:. . :.. ... . .... ..::
XP_016 RLLQRVLRDKEVANRYFTTVCVRLLLESKEKKIREFIQD--FQKLTAADDKTAQVEDFLQ
1200 1210 1220 1230 1240 1250
200 210 220 230 240 250
pF1KE4 --YHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQKRIR
: .:. . .. . :... . ::. .:.:..: .: :. : .: .....:.
XP_016 FLYGAMAQDVIWQN-ASEEQLQDAQLAIERSVMNRIFKLAFYPNQDGDILRDQVLHEHIQ
1260 1270 1280 1290 1300 1310
260 270 280 290 300 310
pF1KE4 AL-RWVTPQMLCVPVNEDIPEVSDMVV---KAITDIIEMDSKRVPRDKLACITKCSKHIF
: . :: . . .:::: . .: ..: ... ..::::. :: . . :.
XP_016 RLSKVVTANHRAL----QIPEVYLREAPWPSAQSEIRTISAYKTPRDKVQCILRMCSTIM
1320 1330 1340 1350 1360
320 330 340 350 360 370
pF1KE4 NAIKITKNEPA-SADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTN
: ....... . .::::.:.:.....:.::: : :..:::. : . ..::..:.. .
XP_016 NLLSLANEDSVPGADDFVPVLVFVLIKANPPCLLSTVQYISSF--YASCLSGEESYWWMQ
1370 1380 1390 1400 1410 1420
380 390 400 410 420 430
pF1KE4 LCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPDACLGVKQMYKNLDLLS
. :: ::. .:
XP_016 FTAAVEFIKTIDDRK
1430
>>XP_006717107 (OMIM: 611714) PREDICTED: GTPase-activati (1439 aa)
initn: 221 init1: 130 opt: 290 Z-score: 284.8 bits: 63.7 E(85289): 4e-09
Smith-Waterman score: 290; 26.1% identity (64.9% similar) in 222 aa overlap (172-384:1224-1436)
150 160 170 180 190
pF1KE4 NRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEGMHYKRDLSIEEQSECAQDF--
:. . :.. ... . .... ..::
XP_006 RLLQRVLRDKEVANRYFTTVCVRLLLESKEKKIREFIQD--FQKLTAADDKTAQVEDFLQ
1200 1210 1220 1230 1240 1250
200 210 220 230 240 250
pF1KE4 --YHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQKRIR
: .:. . .. . :... . ::. .:.:..: .: :. : .: .....:.
XP_006 FLYGAMAQDVIWQN-ASEEQLQDAQLAIERSVMNRIFKLAFYPNQDGDILRDQVLHEHIQ
1260 1270 1280 1290 1300 1310
260 270 280 290 300 310
pF1KE4 AL-RWVTPQMLCVPVNEDIPEVSDMVV---KAITDIIEMDSKRVPRDKLACITKCSKHIF
: . :: . . .:::: . .: ..: ... ..::::. :: . . :.
XP_006 RLSKVVTANHRAL----QIPEVYLREAPWPSAQSEIRTISAYKTPRDKVQCILRMCSTIM
1320 1330 1340 1350 1360
320 330 340 350 360 370
pF1KE4 NAIKITKNEPA-SADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTN
: ....... . .::::.:.:.....:.::: : :..:::. : . ..::..:.. .
XP_006 NLLSLANEDSVPGADDFVPVLVFVLIKANPPCLLSTVQYISSF--YASCLSGEESYWWMQ
1370 1380 1390 1400 1410 1420
380 390 400 410 420 430
pF1KE4 LCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPDACLGVKQMYKNLDLLS
. :: ::. .:
XP_006 FTAAVEFIKTIDDRK
1430
505 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 03:24:38 2016 done: Sun Nov 6 03:24:39 2016
Total Scan time: 9.200 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]