Result of FASTA (omim) for
pFN21AE4074
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4074, 400 aa
1>>>pF1KE4074 400 - 400 aa - 400 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2179+/-0.000406; mu= 17.2127+/- 0.025
mean_var=66.6213+/-13.457, 0's: 0 Z-trim(111.2): 111 B-trim: 604 in 1/53
Lambda= 0.157133
statistics sampled from 19561 (19673) to 19561 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.605), E-opt: 0.2 (0.231), width: 16
Scan time: 8.270
The best scores are: opt bits E(85289)
NP_060671 (OMIM: 616218) TBC1 domain family member ( 400) 2697 620.6 2e-177
XP_005252117 (OMIM: 616218) PREDICTED: TBC1 domain ( 324) 2189 505.4 7.8e-143
NP_001273701 (OMIM: 616218) TBC1 domain family mem ( 275) 1217 285.0 1.5e-76
XP_016863057 (OMIM: 615740) PREDICTED: TBC1 domain ( 444) 272 70.9 6.7e-12
XP_016863052 (OMIM: 615740) PREDICTED: TBC1 domain ( 659) 272 71.0 9.3e-12
XP_016863054 (OMIM: 615740) PREDICTED: TBC1 domain ( 659) 272 71.0 9.3e-12
XP_016863055 (OMIM: 615740) PREDICTED: TBC1 domain ( 659) 272 71.0 9.3e-12
XP_016863053 (OMIM: 615740) PREDICTED: TBC1 domain ( 659) 272 71.0 9.3e-12
XP_016863056 (OMIM: 615740) PREDICTED: TBC1 domain ( 659) 272 71.0 9.3e-12
XP_011532589 (OMIM: 615740) PREDICTED: TBC1 domain ( 681) 272 71.0 9.5e-12
XP_005265673 (OMIM: 615740) PREDICTED: TBC1 domain ( 681) 272 71.0 9.5e-12
XP_005265672 (OMIM: 615740) PREDICTED: TBC1 domain ( 681) 272 71.0 9.5e-12
XP_016863051 (OMIM: 615740) PREDICTED: TBC1 domain ( 681) 272 71.0 9.5e-12
XP_016863049 (OMIM: 615740) PREDICTED: TBC1 domain ( 795) 272 71.1 1.1e-11
XP_016863048 (OMIM: 615740) PREDICTED: TBC1 domain ( 795) 272 71.1 1.1e-11
XP_016863047 (OMIM: 615740) PREDICTED: TBC1 domain ( 795) 272 71.1 1.1e-11
XP_016863046 (OMIM: 615740) PREDICTED: TBC1 domain ( 795) 272 71.1 1.1e-11
XP_005265671 (OMIM: 615740) PREDICTED: TBC1 domain ( 795) 272 71.1 1.1e-11
XP_016863050 (OMIM: 615740) PREDICTED: TBC1 domain ( 795) 272 71.1 1.1e-11
NP_055559 (OMIM: 615740) TBC1 domain family member ( 795) 272 71.1 1.1e-11
XP_016863042 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 272 71.1 1.1e-11
XP_006713493 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 272 71.1 1.1e-11
XP_011532583 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 272 71.1 1.1e-11
XP_011532585 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 272 71.1 1.1e-11
XP_011532586 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 272 71.1 1.1e-11
NP_001127853 (OMIM: 615740) TBC1 domain family mem ( 817) 272 71.1 1.1e-11
XP_016863043 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 272 71.1 1.1e-11
XP_011532588 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 272 71.1 1.1e-11
XP_005265669 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 272 71.1 1.1e-11
XP_005265668 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 272 71.1 1.1e-11
XP_016863044 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 272 71.1 1.1e-11
XP_016863041 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 272 71.1 1.1e-11
XP_016863045 (OMIM: 615740) PREDICTED: TBC1 domain ( 817) 272 71.1 1.1e-11
XP_016875317 (OMIM: 612662) PREDICTED: TBC1 domain ( 530) 239 63.5 1.4e-09
XP_016875314 (OMIM: 612662) PREDICTED: TBC1 domain ( 575) 239 63.5 1.5e-09
XP_016875315 (OMIM: 612662) PREDICTED: TBC1 domain ( 575) 239 63.5 1.5e-09
NP_001139685 (OMIM: 612662) TBC1 domain family mem ( 674) 239 63.6 1.7e-09
NP_001139686 (OMIM: 612662) TBC1 domain family mem ( 682) 239 63.6 1.7e-09
NP_001271232 (OMIM: 616879) TBC1 domain family mem ( 439) 235 62.5 2.2e-09
XP_016884234 (OMIM: 616879) PREDICTED: TBC1 domain ( 458) 235 62.6 2.3e-09
NP_001271234 (OMIM: 616879) TBC1 domain family mem ( 470) 235 62.6 2.4e-09
XP_016884233 (OMIM: 616879) PREDICTED: TBC1 domain ( 470) 235 62.6 2.4e-09
NP_001271233 (OMIM: 616879) TBC1 domain family mem ( 487) 235 62.6 2.4e-09
NP_055161 (OMIM: 616879) TBC1 domain family member ( 517) 235 62.6 2.5e-09
XP_006719630 (OMIM: 612662) PREDICTED: TBC1 domain ( 445) 234 62.3 2.6e-09
XP_011536984 (OMIM: 612662) PREDICTED: TBC1 domain ( 445) 234 62.3 2.6e-09
XP_016875316 (OMIM: 612662) PREDICTED: TBC1 domain ( 547) 234 62.4 3.1e-09
XP_011536982 (OMIM: 612662) PREDICTED: TBC1 domain ( 592) 234 62.4 3.3e-09
XP_011536981 (OMIM: 612662) PREDICTED: TBC1 domain ( 592) 234 62.4 3.3e-09
XP_006719629 (OMIM: 612662) PREDICTED: TBC1 domain ( 592) 234 62.4 3.3e-09
>>NP_060671 (OMIM: 616218) TBC1 domain family member 13 (400 aa)
initn: 2697 init1: 2697 opt: 2697 Z-score: 3306.3 bits: 620.6 E(85289): 2e-177
Smith-Waterman score: 2697; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KE4 MSSLHKSRIADFQDVLKEPSIALEKLRELSFSGIPCEGGLRCLCWKILLNYLPLERASWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MSSLHKSRIADFQDVLKEPSIALEKLRELSFSGIPCEGGLRCLCWKILLNYLPLERASWT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 SILAKQRELYAQFLREMIIQPGIAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SILAKQRELYAQFLREMIIQPGIAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LQIDKDVRRLCPDISFFQRATDYPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LQIDKDVRRLCPDISFFQRATDYPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 NMSSPHKNSVPSSLNEYEVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 NMSSPHKNSVPSSLNEYEVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 TFATDPNSEWKEHAEADTFFCFTNLMAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TFATDPNSEWKEHAEADTFFCFTNLMAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 ELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLM
310 320 330 340 350 360
370 380 390 400
pF1KE4 LIREQLLEGDFTVNMRLLQDYPITDVCQILQKAKELQDSK
::::::::::::::::::::::::::::::::::::::::
NP_060 LIREQLLEGDFTVNMRLLQDYPITDVCQILQKAKELQDSK
370 380 390 400
>>XP_005252117 (OMIM: 616218) PREDICTED: TBC1 domain fam (324 aa)
initn: 2189 init1: 2189 opt: 2189 Z-score: 2685.3 bits: 505.4 E(85289): 7.8e-143
Smith-Waterman score: 2189; 100.0% identity (100.0% similar) in 324 aa overlap (77-400:1-324)
50 60 70 80 90 100
pF1KE4 ILLNYLPLERASWTSILAKQRELYAQFLREMIIQPGIAKANMGVSREDVTFEDHPLNPNP
::::::::::::::::::::::::::::::
XP_005 MIIQPGIAKANMGVSREDVTFEDHPLNPNP
10 20 30
110 120 130 140 150 160
pF1KE4 DSRWNTYFKDNEVLLQIDKDVRRLCPDISFFQRATDYPCLLILDPQNEFETLRKRVEQTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSRWNTYFKDNEVLLQIDKDVRRLCPDISFFQRATDYPCLLILDPQNEFETLRKRVEQTT
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE4 LKSQTVARNRSGVTNMSSPHKNSVPSSLNEYEVLPNGCEAHWEVVERILFIYAKLNPGIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKSQTVARNRSGVTNMSSPHKNSVPSSLNEYEVLPNGCEAHWEVVERILFIYAKLNPGIA
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE4 YVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNFIKSLDDSQCGITY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNFIKSLDDSQCGITY
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE4 KMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDN
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE4 RFDFLLLVCCAMLMLIREQLLEGDFTVNMRLLQDYPITDVCQILQKAKELQDSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RFDFLLLVCCAMLMLIREQLLEGDFTVNMRLLQDYPITDVCQILQKAKELQDSK
280 290 300 310 320
>>NP_001273701 (OMIM: 616218) TBC1 domain family member (275 aa)
initn: 1838 init1: 1217 opt: 1217 Z-score: 1495.5 bits: 285.0 E(85289): 1.5e-76
Smith-Waterman score: 1592; 68.8% identity (68.8% similar) in 400 aa overlap (1-400:1-275)
10 20 30 40 50 60
pF1KE4 MSSLHKSRIADFQDVLKEPSIALEKLRELSFSGIPCEGGLRCLCWKILLNYLPLERASWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSLHKSRIADFQDVLKEPSIALEKLRELSFSGIPCEGGLRCLCWKILLNYLPLERASWT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 SILAKQRELYAQFLREMIIQPGIAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SILAKQRELYAQFLREMIIQPGIAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LQIDKDVRRLCPDISFFQRATDYPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQIDKDVRRLCPDISFFQRATDYPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 NMSSPHKNSVPSSLNEYEVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYY
:
NP_001 N-----------------------------------------------------------
250 260 270 280 290 300
pF1KE4 TFATDPNSEWKEHAEADTFFCFTNLMAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDV
NP_001 ------------------------------------------------------------
310 320 330 340 350 360
pF1KE4 ELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ------QEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLM
190 200 210 220 230
370 380 390 400
pF1KE4 LIREQLLEGDFTVNMRLLQDYPITDVCQILQKAKELQDSK
::::::::::::::::::::::::::::::::::::::::
NP_001 LIREQLLEGDFTVNMRLLQDYPITDVCQILQKAKELQDSK
240 250 260 270
>>XP_016863057 (OMIM: 615740) PREDICTED: TBC1 domain fam (444 aa)
initn: 508 init1: 243 opt: 272 Z-score: 334.6 bits: 70.9 E(85289): 6.7e-12
Smith-Waterman score: 422; 26.8% identity (56.7% similar) in 381 aa overlap (23-400:69-415)
10 20 30 40 50
pF1KE4 MSSLHKSRIADFQDVLKEPSIALEKLRELSFSGIPCEGGLRCLCWKILLNYL
: .:. ...: . .: .:::..: :
XP_016 GRRTSSTLDSEGTFNSYRKEWEELFVNNNYLATIRQKGINGQLRSSRFRSICWKLFLCVL
40 50 60 70 80 90
60 70 80 90 100 110
pF1KE4 PLERASWTSILAKQRELYAQFLREMIIQPGIAKANMGVSREDVTFEDHPLNPNPDSRWNT
: ....: : . . : :... . : .: :. :...:. . ..::. . : ::
XP_016 PQDKSQWISRIEELRAWYSNIKEIHITNP--RKV---VGQQDLMI-NNPLSQDEGSLWNK
100 110 120 130 140 150
120 130 140 150 160 170
pF1KE4 YFKDNEVLLQIDKDVRRLCPDISFFQRATDYPCLLILDPQNEFETLRKRVEQTTLKSQTV
.:.:.:. .:..::.: :...:::. . : . . .. :: :.
XP_016 FFQDKELRSMIEQDVKRTFPEMQFFQQENVRKIL-----TDVLFCYARENEQLLYKQGMH
160 170 180 190 200
180 190 200 210 220 230
pF1KE4 ARNRSGVTNMSSPHKNSVPSSLNEYEVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMN
: . :. . .: . . :. : .. .: . . : . .
XP_016 ELLAPIVFVLHCDHQAFLHASES---AQPS------EEMKTVLNPEYLEHDAYAVFSQLM
210 220 230 240 250
240 250 260 270 280 290
pF1KE4 EIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNFIKSLD-DSQCGITYKMEKV
: . : . :: : ... :: .::. : : . : .:. :....
XP_016 ETAEPWFSTFEHD-GQKGKE-----------TLMTPI--PFARPQDLGPTIAIVTKVNQI
260 270 280 290 300
300 310 320 330 340 350
pF1KE4 YS-TLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDF
. :: .:.:::..:.. .: ::....::. ::...:: : :.. .::.:::: . .
XP_016 QDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGLSLGL
310 320 330 340 350 360
360 370 380 390 400
pF1KE4 LLLVCCAMLMLIREQLLEGDFTVNMRLLQDYP-ITDVCQILQKAKELQDSK
. . :::. ::. :. ... . . ::. :: : :: ... :: :.: :
XP_016 VDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRPVTYQ
370 380 390 400 410 420
XP_016 FHPNLDYYKARGADLMNKSR
430 440
>>XP_016863052 (OMIM: 615740) PREDICTED: TBC1 domain fam (659 aa)
initn: 436 init1: 243 opt: 272 Z-score: 332.1 bits: 71.0 E(85289): 9.3e-12
Smith-Waterman score: 338; 27.2% identity (55.4% similar) in 305 aa overlap (99-400:3-279)
70 80 90 100 110 120
pF1KE4 LYAQFLREMIIQPGIAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVLLQIDKDVR
..::. . : :: .:.:.:. .:..::.
XP_016 MINNPLSQDEGSLWNKFFQDKELRSMIEQDVK
10 20 30
130 140 150 160 170 180
pF1KE4 RLCPDISFFQRATDYPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVTNMSSPHKN
: :...:::. . : . . .. :: :. : . :.
XP_016 RTFPEMQFFQQENVRKILT-----DVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQA
40 50 60 70 80
190 200 210 220 230 240
pF1KE4 SVPSSLNEYEVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNS
. .: . :. : .. .: . . : . . : . : . :: : ..
XP_016 FLHASESAQ---PS------EEMKTVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHD-GQ
90 100 110 120 130
250 260 270 280 290 300
pF1KE4 EWKEHAEADTFFCFTNLMAEIRDNFIKSLD-DSQCGITYKMEKVYS-TLKDKDVELYLKL
. :: .::. : : . : .:. :.... . :: .:.:::..:
XP_016 KGKE-----------TLMTPI--PFARPQDLGPTIAIVTKVNQIQDHLLKKHDIELYMHL
140 150 160 170 180
310 320 330 340 350 360
pF1KE4 QEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLMLIREQL
.. .: ::....::. ::...:: : :.. .::.:::: . .. . :::. ::. :
XP_016 NRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGLSLGLVDYIFVAMLLYIRDAL
190 200 210 220 230 240
370 380 390 400
pF1KE4 LEGDFTVNMRLLQDYP-ITDVCQILQKAKELQDSK
. ... . . ::. :: : :: ... :: :.: :
XP_016 ISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRPVTYQFHPNLDYYKARGADLM
250 260 270 280 290 300
XP_016 NKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGGPVPGGNSSSSSSVVIPTRTS
310 320 330 340 350 360
>>XP_016863054 (OMIM: 615740) PREDICTED: TBC1 domain fam (659 aa)
initn: 436 init1: 243 opt: 272 Z-score: 332.1 bits: 71.0 E(85289): 9.3e-12
Smith-Waterman score: 338; 27.2% identity (55.4% similar) in 305 aa overlap (99-400:3-279)
70 80 90 100 110 120
pF1KE4 LYAQFLREMIIQPGIAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVLLQIDKDVR
..::. . : :: .:.:.:. .:..::.
XP_016 MINNPLSQDEGSLWNKFFQDKELRSMIEQDVK
10 20 30
130 140 150 160 170 180
pF1KE4 RLCPDISFFQRATDYPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVTNMSSPHKN
: :...:::. . : . . .. :: :. : . :.
XP_016 RTFPEMQFFQQENVRKILT-----DVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQA
40 50 60 70 80
190 200 210 220 230 240
pF1KE4 SVPSSLNEYEVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNS
. .: . :. : .. .: . . : . . : . : . :: : ..
XP_016 FLHASESAQ---PS------EEMKTVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHD-GQ
90 100 110 120 130
250 260 270 280 290 300
pF1KE4 EWKEHAEADTFFCFTNLMAEIRDNFIKSLD-DSQCGITYKMEKVYS-TLKDKDVELYLKL
. :: .::. : : . : .:. :.... . :: .:.:::..:
XP_016 KGKE-----------TLMTPI--PFARPQDLGPTIAIVTKVNQIQDHLLKKHDIELYMHL
140 150 160 170 180
310 320 330 340 350 360
pF1KE4 QEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLMLIREQL
.. .: ::....::. ::...:: : :.. .::.:::: . .. . :::. ::. :
XP_016 NRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGLSLGLVDYIFVAMLLYIRDAL
190 200 210 220 230 240
370 380 390 400
pF1KE4 LEGDFTVNMRLLQDYP-ITDVCQILQKAKELQDSK
. ... . . ::. :: : :: ... :: :.: :
XP_016 ISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRPVTYQFHPNLDYYKARGADLM
250 260 270 280 290 300
XP_016 NKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGGPVPGGNSSSSSSVVIPTRTS
310 320 330 340 350 360
>>XP_016863055 (OMIM: 615740) PREDICTED: TBC1 domain fam (659 aa)
initn: 436 init1: 243 opt: 272 Z-score: 332.1 bits: 71.0 E(85289): 9.3e-12
Smith-Waterman score: 338; 27.2% identity (55.4% similar) in 305 aa overlap (99-400:3-279)
70 80 90 100 110 120
pF1KE4 LYAQFLREMIIQPGIAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVLLQIDKDVR
..::. . : :: .:.:.:. .:..::.
XP_016 MINNPLSQDEGSLWNKFFQDKELRSMIEQDVK
10 20 30
130 140 150 160 170 180
pF1KE4 RLCPDISFFQRATDYPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVTNMSSPHKN
: :...:::. . : . . .. :: :. : . :.
XP_016 RTFPEMQFFQQENVRKILT-----DVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQA
40 50 60 70 80
190 200 210 220 230 240
pF1KE4 SVPSSLNEYEVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNS
. .: . :. : .. .: . . : . . : . : . :: : ..
XP_016 FLHASESAQ---PS------EEMKTVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHD-GQ
90 100 110 120 130
250 260 270 280 290 300
pF1KE4 EWKEHAEADTFFCFTNLMAEIRDNFIKSLD-DSQCGITYKMEKVYS-TLKDKDVELYLKL
. :: .::. : : . : .:. :.... . :: .:.:::..:
XP_016 KGKE-----------TLMTPI--PFARPQDLGPTIAIVTKVNQIQDHLLKKHDIELYMHL
140 150 160 170 180
310 320 330 340 350 360
pF1KE4 QEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLMLIREQL
.. .: ::....::. ::...:: : :.. .::.:::: . .. . :::. ::. :
XP_016 NRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGLSLGLVDYIFVAMLLYIRDAL
190 200 210 220 230 240
370 380 390 400
pF1KE4 LEGDFTVNMRLLQDYP-ITDVCQILQKAKELQDSK
. ... . . ::. :: : :: ... :: :.: :
XP_016 ISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRPVTYQFHPNLDYYKARGADLM
250 260 270 280 290 300
XP_016 NKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGGPVPGGNSSSSSSVVIPTRTS
310 320 330 340 350 360
>>XP_016863053 (OMIM: 615740) PREDICTED: TBC1 domain fam (659 aa)
initn: 436 init1: 243 opt: 272 Z-score: 332.1 bits: 71.0 E(85289): 9.3e-12
Smith-Waterman score: 338; 27.2% identity (55.4% similar) in 305 aa overlap (99-400:3-279)
70 80 90 100 110 120
pF1KE4 LYAQFLREMIIQPGIAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVLLQIDKDVR
..::. . : :: .:.:.:. .:..::.
XP_016 MINNPLSQDEGSLWNKFFQDKELRSMIEQDVK
10 20 30
130 140 150 160 170 180
pF1KE4 RLCPDISFFQRATDYPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVTNMSSPHKN
: :...:::. . : . . .. :: :. : . :.
XP_016 RTFPEMQFFQQENVRKILT-----DVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQA
40 50 60 70 80
190 200 210 220 230 240
pF1KE4 SVPSSLNEYEVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNS
. .: . :. : .. .: . . : . . : . : . :: : ..
XP_016 FLHASESAQ---PS------EEMKTVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHD-GQ
90 100 110 120 130
250 260 270 280 290 300
pF1KE4 EWKEHAEADTFFCFTNLMAEIRDNFIKSLD-DSQCGITYKMEKVYS-TLKDKDVELYLKL
. :: .::. : : . : .:. :.... . :: .:.:::..:
XP_016 KGKE-----------TLMTPI--PFARPQDLGPTIAIVTKVNQIQDHLLKKHDIELYMHL
140 150 160 170 180
310 320 330 340 350 360
pF1KE4 QEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLMLIREQL
.. .: ::....::. ::...:: : :.. .::.:::: . .. . :::. ::. :
XP_016 NRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGLSLGLVDYIFVAMLLYIRDAL
190 200 210 220 230 240
370 380 390 400
pF1KE4 LEGDFTVNMRLLQDYP-ITDVCQILQKAKELQDSK
. ... . . ::. :: : :: ... :: :.: :
XP_016 ISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRPVTYQFHPNLDYYKARGADLM
250 260 270 280 290 300
XP_016 NKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGGPVPGGNSSSSSSVVIPTRTS
310 320 330 340 350 360
>>XP_016863056 (OMIM: 615740) PREDICTED: TBC1 domain fam (659 aa)
initn: 436 init1: 243 opt: 272 Z-score: 332.1 bits: 71.0 E(85289): 9.3e-12
Smith-Waterman score: 338; 27.2% identity (55.4% similar) in 305 aa overlap (99-400:3-279)
70 80 90 100 110 120
pF1KE4 LYAQFLREMIIQPGIAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVLLQIDKDVR
..::. . : :: .:.:.:. .:..::.
XP_016 MINNPLSQDEGSLWNKFFQDKELRSMIEQDVK
10 20 30
130 140 150 160 170 180
pF1KE4 RLCPDISFFQRATDYPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVTNMSSPHKN
: :...:::. . : . . .. :: :. : . :.
XP_016 RTFPEMQFFQQENVRKILT-----DVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQA
40 50 60 70 80
190 200 210 220 230 240
pF1KE4 SVPSSLNEYEVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNS
. .: . :. : .. .: . . : . . : . : . :: : ..
XP_016 FLHASESAQ---PS------EEMKTVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHD-GQ
90 100 110 120 130
250 260 270 280 290 300
pF1KE4 EWKEHAEADTFFCFTNLMAEIRDNFIKSLD-DSQCGITYKMEKVYS-TLKDKDVELYLKL
. :: .::. : : . : .:. :.... . :: .:.:::..:
XP_016 KGKE-----------TLMTPI--PFARPQDLGPTIAIVTKVNQIQDHLLKKHDIELYMHL
140 150 160 170 180
310 320 330 340 350 360
pF1KE4 QEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLMLIREQL
.. .: ::....::. ::...:: : :.. .::.:::: . .. . :::. ::. :
XP_016 NRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGLSLGLVDYIFVAMLLYIRDAL
190 200 210 220 230 240
370 380 390 400
pF1KE4 LEGDFTVNMRLLQDYP-ITDVCQILQKAKELQDSK
. ... . . ::. :: : :: ... :: :.: :
XP_016 ISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRPVTYQFHPNLDYYKARGADLM
250 260 270 280 290 300
XP_016 NKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGGPVPGGNSSSSSSVVIPTRTS
310 320 330 340 350 360
>>XP_011532589 (OMIM: 615740) PREDICTED: TBC1 domain fam (681 aa)
initn: 436 init1: 243 opt: 272 Z-score: 331.9 bits: 71.0 E(85289): 9.5e-12
Smith-Waterman score: 338; 27.2% identity (55.4% similar) in 305 aa overlap (99-400:3-279)
70 80 90 100 110 120
pF1KE4 LYAQFLREMIIQPGIAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVLLQIDKDVR
..::. . : :: .:.:.:. .:..::.
XP_011 MINNPLSQDEGSLWNKFFQDKELRSMIEQDVK
10 20 30
130 140 150 160 170 180
pF1KE4 RLCPDISFFQRATDYPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVTNMSSPHKN
: :...:::. . : . . .. :: :. : . :.
XP_011 RTFPEMQFFQQENVRKILT-----DVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQA
40 50 60 70 80
190 200 210 220 230 240
pF1KE4 SVPSSLNEYEVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNS
. .: . :. : .. .: . . : . . : . : . :: : ..
XP_011 FLHASESAQ---PS------EEMKTVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHD-GQ
90 100 110 120 130
250 260 270 280 290 300
pF1KE4 EWKEHAEADTFFCFTNLMAEIRDNFIKSLD-DSQCGITYKMEKVYS-TLKDKDVELYLKL
. :: .::. : : . : .:. :.... . :: .:.:::..:
XP_011 KGKE-----------TLMTPI--PFARPQDLGPTIAIVTKVNQIQDHLLKKHDIELYMHL
140 150 160 170 180
310 320 330 340 350 360
pF1KE4 QEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLMLIREQL
.. .: ::....::. ::...:: : :.. .::.:::: . .. . :::. ::. :
XP_011 NRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGLSLGLVDYIFVAMLLYIRDAL
190 200 210 220 230 240
370 380 390 400
pF1KE4 LEGDFTVNMRLLQDYP-ITDVCQILQKAKELQDSK
. ... . . ::. :: : :: ... :: :.: :
XP_011 ISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRPVTYQFHPNLDYYKARGADLM
250 260 270 280 290 300
XP_011 NKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGGPVPGGNSSSSSSVVIPTRTS
310 320 330 340 350 360
400 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 03:31:40 2016 done: Sun Nov 6 03:31:41 2016
Total Scan time: 8.270 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]