Result of FASTA (omim) for
pFN21AE0525
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0525, 384 aa
1>>>pF1KE0525 384 - 384 aa - 384 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0711+/-0.000378; mu= 18.0698+/- 0.023
mean_var=66.1679+/-13.904, 0's: 0 Z-trim(111.8): 21 B-trim: 1015 in 1/54
Lambda= 0.157671
statistics sampled from 20491 (20510) to 20491 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.24), width: 16
Scan time: 7.610
The best scores are: opt bits E(85289)
NP_057411 (OMIM: 606673,613161) beta-ureidopropion ( 384) 2606 601.9 8.3e-172
XP_011528527 (OMIM: 606673,613161) PREDICTED: beta ( 262) 1796 417.5 1.8e-116
XP_011528524 (OMIM: 606673,613161) PREDICTED: beta ( 411) 1798 418.1 1.9e-116
XP_016884315 (OMIM: 606673,613161) PREDICTED: beta ( 337) 1272 298.4 1.7e-80
XP_011528526 (OMIM: 606673,613161) PREDICTED: beta ( 345) 1171 275.4 1.4e-73
XP_011528525 (OMIM: 606673,613161) PREDICTED: beta ( 348) 1171 275.4 1.4e-73
XP_016884317 (OMIM: 606673,613161) PREDICTED: beta ( 266) 810 193.2 5.9e-49
XP_016884316 (OMIM: 606673,613161) PREDICTED: beta ( 276) 810 193.2 6.1e-49
XP_016884314 (OMIM: 606673,613161) PREDICTED: beta ( 340) 810 193.3 7.2e-49
NP_005591 (OMIM: 604618) nitrilase homolog 1 isofo ( 327) 224 60.0 9.3e-09
XP_005245271 (OMIM: 604618) PREDICTED: nitrilase h ( 344) 224 60.0 9.7e-09
XP_005245272 (OMIM: 604618) PREDICTED: nitrilase h ( 344) 224 60.0 9.7e-09
NP_001172022 (OMIM: 604618) nitrilase homolog 1 is ( 312) 217 58.4 2.7e-08
XP_005245273 (OMIM: 604618) PREDICTED: nitrilase h ( 291) 209 56.5 9.1e-08
NP_001172023 (OMIM: 604618) nitrilase homolog 1 is ( 291) 209 56.5 9.1e-08
NP_064587 (OMIM: 616769) omega-amidase NIT2 [Homo ( 276) 179 49.7 9.8e-06
NP_001172021 (OMIM: 604618) nitrilase homolog 1 is ( 243) 178 49.4 1e-05
XP_006711404 (OMIM: 604618) PREDICTED: nitrilase h ( 260) 178 49.5 1.1e-05
XP_016856860 (OMIM: 604618) PREDICTED: nitrilase h ( 207) 163 46.0 9.7e-05
>>NP_057411 (OMIM: 606673,613161) beta-ureidopropionase (384 aa)
initn: 2606 init1: 2606 opt: 2606 Z-score: 3205.5 bits: 601.9 E(85289): 8.3e-172
Smith-Waterman score: 2606; 100.0% identity (100.0% similar) in 384 aa overlap (1-384:1-384)
10 20 30 40 50 60
pF1KE0 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 WTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 WTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWNT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 AVVISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 AVVISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 NWLMYSINGAEIIFNPSATIGALSESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NWLMYSINGAEIIFNPSATIGALSESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFTS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 GDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTG
310 320 330 340 350 360
370 380
pF1KE0 RYEMYARELAEAVKSNYSPTIVKE
::::::::::::::::::::::::
NP_057 RYEMYARELAEAVKSNYSPTIVKE
370 380
>>XP_011528527 (OMIM: 606673,613161) PREDICTED: beta-ure (262 aa)
initn: 1796 init1: 1796 opt: 1796 Z-score: 2212.1 bits: 417.5 E(85289): 1.8e-116
Smith-Waterman score: 1796; 100.0% identity (100.0% similar) in 262 aa overlap (123-384:1-262)
100 110 120 130 140 150
pF1KE0 VSALHRRIKAIVEVAAMCGVNIICFQEAWTMPFAFCTREKLPWTEFAESAEDGPTTRFCQ
::::::::::::::::::::::::::::::
XP_011 MPFAFCTREKLPWTEFAESAEDGPTTRFCQ
10 20 30
160 170 180 190 200 210
pF1KE0 KLAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYM
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE0 EGNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEA
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE0 RNAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSR
160 170 180 190 200 210
340 350 360 370 380
pF1KE0 SRDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE
220 230 240 250 260
>>XP_011528524 (OMIM: 606673,613161) PREDICTED: beta-ure (411 aa)
initn: 1798 init1: 1798 opt: 1798 Z-score: 2211.8 bits: 418.1 E(85289): 1.9e-116
Smith-Waterman score: 2542; 93.4% identity (93.4% similar) in 411 aa overlap (1-384:1-411)
10 20 30 40 50 60
pF1KE0 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
70 80 90 100 110 120
130 140 150
pF1KE0 WT---------------------------MPFAFCTREKLPWTEFAESAEDGPTTRFCQK
:: :::::::::::::::::::::::::::::::
XP_011 WTAGLGHAGHSFQIYTTPRWLKPSGQRISMPFAFCTREKLPWTEFAESAEDGPTTRFCQK
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE0 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE0 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE0 NAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRS
310 320 330 340 350 360
340 350 360 370 380
pF1KE0 RDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE
370 380 390 400 410
>>XP_016884315 (OMIM: 606673,613161) PREDICTED: beta-ure (337 aa)
initn: 1272 init1: 1272 opt: 1272 Z-score: 1566.4 bits: 298.4 E(85289): 1.7e-80
Smith-Waterman score: 2016; 91.9% identity (91.9% similar) in 332 aa overlap (1-305:1-332)
10 20 30 40 50 60
pF1KE0 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
70 80 90 100 110 120
130 140 150
pF1KE0 WT---------------------------MPFAFCTREKLPWTEFAESAEDGPTTRFCQK
:: :::::::::::::::::::::::::::::::
XP_016 WTAGLGHAGHSFQIYTTPRWLKPSGQRISMPFAFCTREKLPWTEFAESAEDGPTTRFCQK
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE0 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE0 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE0 NAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRS
::::::::::::::::::::::::::::::::
XP_016 NAAIANHCFTCAINRVGTEHFPNEFTSGDGKKDDGQV
310 320 330
340 350 360 370 380
pF1KE0 RDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE
>>XP_011528526 (OMIM: 606673,613161) PREDICTED: beta-ure (345 aa)
initn: 1325 init1: 1171 opt: 1171 Z-score: 1442.0 bits: 275.4 E(85289): 1.4e-73
Smith-Waterman score: 1941; 77.4% identity (77.4% similar) in 411 aa overlap (1-384:1-345)
10 20 30 40 50 60
pF1KE0 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
70 80 90 100 110 120
130 140 150
pF1KE0 WT---------------------------MPFAFCTREKLPWTEFAESAEDGPTTRFCQK
:: :::::::::::::::::::::::::::::::
XP_011 WTAGLGHAGHSFQIYTTPRWLKPSGQRISMPFAFCTREKLPWTEFAESAEDGPTTRFCQK
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE0 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE0 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE0 NAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRS
::::::::::::::::::
XP_011 NAAIANHCFTCAINRVGT------------------------------------------
310
340 350 360 370 380
pF1KE0 RDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE
:::::::::::::::::::::::::::
XP_011 ------------------------MTGRYEMYARELAEAVKSNYSPTIVKE
320 330 340
>>XP_011528525 (OMIM: 606673,613161) PREDICTED: beta-ure (348 aa)
initn: 1171 init1: 1171 opt: 1171 Z-score: 1442.0 bits: 275.4 E(85289): 1.4e-73
Smith-Waterman score: 1915; 91.5% identity (91.5% similar) in 318 aa overlap (1-291:1-318)
10 20 30 40 50 60
pF1KE0 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
70 80 90 100 110 120
130 140 150
pF1KE0 WT---------------------------MPFAFCTREKLPWTEFAESAEDGPTTRFCQK
:: :::::::::::::::::::::::::::::::
XP_011 WTAGLGHAGHSFQIYTTPRWLKPSGQRISMPFAFCTREKLPWTEFAESAEDGPTTRFCQK
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE0 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE0 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE0 NAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRS
::::::::::::::::::
XP_011 NAAIANHCFTCAINRVGTIMNSPKAPSRFLPRLSNSPLAQGWLLSRSV
310 320 330 340
>>XP_016884317 (OMIM: 606673,613161) PREDICTED: beta-ure (266 aa)
initn: 810 init1: 810 opt: 810 Z-score: 999.9 bits: 193.2 E(85289): 5.9e-49
Smith-Waterman score: 1330; 88.5% identity (88.5% similar) in 234 aa overlap (1-207:1-234)
10 20 30 40 50 60
pF1KE0 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
70 80 90 100 110 120
130 140 150
pF1KE0 WT---------------------------MPFAFCTREKLPWTEFAESAEDGPTTRFCQK
:: :::::::::::::::::::::::::::::::
XP_016 WTAGLGHAGHSFQIYTTPRWLKPSGQRISMPFAFCTREKLPWTEFAESAEDGPTTRFCQK
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE0 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNERVPVAH
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE0 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
XP_016 RGQKRSHCQSLLHLRHQSSGHHDGQV
250 260
>>XP_016884316 (OMIM: 606673,613161) PREDICTED: beta-ure (276 aa)
initn: 810 init1: 810 opt: 810 Z-score: 999.6 bits: 193.2 E(85289): 6.1e-49
Smith-Waterman score: 1330; 88.5% identity (88.5% similar) in 234 aa overlap (1-207:1-234)
10 20 30 40 50 60
pF1KE0 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
70 80 90 100 110 120
130 140 150
pF1KE0 WT---------------------------MPFAFCTREKLPWTEFAESAEDGPTTRFCQK
:: :::::::::::::::::::::::::::::::
XP_016 WTAGLGHAGHSFQIYTTPRWLKPSGQRISMPFAFCTREKLPWTEFAESAEDGPTTRFCQK
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE0 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNERVPVAH
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE0 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
XP_016 RGQKRSHCQSLLHLRHQSSGHRALPERVYLGRWKER
250 260 270
>>XP_016884314 (OMIM: 606673,613161) PREDICTED: beta-ure (340 aa)
initn: 1317 init1: 810 opt: 810 Z-score: 998.3 bits: 193.3 E(85289): 7.2e-49
Smith-Waterman score: 1717; 71.3% identity (73.7% similar) in 411 aa overlap (1-384:1-340)
10 20 30 40 50 60
pF1KE0 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEA
70 80 90 100 110 120
130 140 150
pF1KE0 WT---------------------------MPFAFCTREKLPWTEFAESAEDGPTTRFCQK
:: :::::::::::::::::::::::::::::::
XP_016 WTAGLGHAGHSFQIYTTPRWLKPSGQRISMPFAFCTREKLPWTEFAESAEDGPTTRFCQK
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE0 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYME
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNE------
190 200 210 220 230
220 230 240 250 260 270
pF1KE0 GNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEAR
:. :. :
XP_016 -------------RV----------------------------------------PVAHR
240
280 290 300 310 320 330
pF1KE0 NAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRS
. .:: . :. .. .:: . :::::::::::::::::::::::::::
XP_016 GQK-RSHCQSLL-------HLRHQ-SSG---HPHQDFGYFYGSSYVAAPDSSRTPGLSRS
250 260 270 280
340 350 360 370 380
pF1KE0 RDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE
290 300 310 320 330 340
>>NP_005591 (OMIM: 604618) nitrilase homolog 1 isoform 1 (327 aa)
initn: 237 init1: 152 opt: 224 Z-score: 278.2 bits: 60.0 E(85289): 9.3e-09
Smith-Waterman score: 245; 26.9% identity (52.4% similar) in 294 aa overlap (68-350:33-304)
40 50 60 70 80 90
pF1KE0 DLPREAFEAASREDFELQGYAFEAAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALH
::: . .. . ..:: : :. . .
NP_005 GFITRPPHRFLSLLCPGLRIPQLSVLCAQPRPRAMAISSSSCELPLVAVCQVTSTPDKQQ
10 20 30 40 50 60
100 110 120 130 140 150
pF1KE0 --RRIKAIVEVAAMCGVNIICFQEAWTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLA
. .:. :: :. . . :: : : .:. ...: : . .::
NP_005 NFKTCAELVREAARLGACLAFLPEA----FDFIARDPAETLHLSEPL-GGKLLEEYTQLA
70 80 90 100 110
160 170 180 190 200
pF1KE0 KNHDM-VVVSPILER--DSEHGDVLWNTAVVISNSGAVLGKTRKNH-----IPRVGDFNE
.. . . .. . :: : :. . ..: :.....:::.. ::.: :: : . :
NP_005 RECGLWLSLGGFHERGQDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCE
120 130 140 150 160 170
210 220 230 240 250 260
pF1KE0 STYYMEG-NLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSES
:. : : .: :: .: :.:.. .:: . : : . ::::. ::: . . .
NP_005 SNSTMPGPSLESPV-STPAGKIGLAVCYDMRFPELSLALAQAGAEILTYPSAFGSITGPA
180 190 200 210 220 230
270 280 290 300 310 320
pF1KE0 LWPIEARNAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSR
: . : :: ..:.. : . : .: :.: :: :.:. : ..
NP_005 HWEVLLRARAIETQCYVVAAAQCGRHHE---------KRAS------YGHSMVVDPWGTV
240 250 260 270 280
330 340 350 360 370 380
pF1KE0 TPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE
. :.. :: .:..::: .:.
NP_005 VARCSEG-PGLCLARIDLNYLRQLRRHLPVFQHRRPDLYGNLGHPLS
290 300 310 320
384 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 01:56:44 2016 done: Thu Nov 3 01:56:45 2016
Total Scan time: 7.610 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]