Result of FASTA (ccds) for
pFN21AE0458
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0458, 226 aa
1>>>pF1KE0458 226 - 226 aa - 226 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3363+/-0.000683; mu= 13.3310+/- 0.041
mean_var=60.9962+/-12.241, 0's: 0 Z-trim(109.6): 22 B-trim: 17 in 1/49
Lambda= 0.164219
statistics sampled from 10970 (10990) to 10970 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.338), width: 16
Scan time: 2.240
The best scores are: opt bits E(32554)
CCDS8957.1 METTL21B gene_id:25895|Hs108|chr12 ( 226) 1534 371.5 2.5e-103
CCDS31848.1 METTL21B gene_id:25895|Hs108|chr12 ( 149) 653 162.7 1.2e-40
CCDS2376.1 METTL21A gene_id:151194|Hs108|chr2 ( 218) 540 136.0 1.9e-32
CCDS32003.1 METTL21C gene_id:196541|Hs108|chr13 ( 264) 303 79.8 1.8e-15
CCDS9696.2 VCPKMT gene_id:79609|Hs108|chr14 ( 229) 286 75.8 2.6e-14
CCDS41951.1 VCPKMT gene_id:79609|Hs108|chr14 ( 194) 273 72.7 1.9e-13
CCDS82562.1 METTL21A gene_id:151194|Hs108|chr2 ( 90) 231 62.6 9.5e-11
>>CCDS8957.1 METTL21B gene_id:25895|Hs108|chr12 (226 aa)
initn: 1534 init1: 1534 opt: 1534 Z-score: 1968.5 bits: 371.5 E(32554): 2.5e-103
Smith-Waterman score: 1534; 100.0% identity (100.0% similar) in 226 aa overlap (1-226:1-226)
10 20 30 40 50 60
pF1KE0 MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 LSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 PAGGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 PAGGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLAS
130 140 150 160 170 180
190 200 210 220
pF1KE0 KMRKEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHREPRPA
::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 KMRKEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHREPRPA
190 200 210 220
>>CCDS31848.1 METTL21B gene_id:25895|Hs108|chr12 (149 aa)
initn: 653 init1: 653 opt: 653 Z-score: 843.3 bits: 162.7 E(32554): 1.2e-40
Smith-Waterman score: 653; 100.0% identity (100.0% similar) in 97 aa overlap (1-97:1-97)
10 20 30 40 50 60
pF1KE0 MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANV
:::::::::::::::::::::::::::::::::::::
CCDS31 LSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGAYGLVRETEDDVIEQELWRGMRG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 PAGGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLAS
CCDS31 ACGHALSMSTMTPWESIKGSSVRGGCYHH
130 140
>>CCDS2376.1 METTL21A gene_id:151194|Hs108|chr2 (218 aa)
initn: 449 init1: 278 opt: 540 Z-score: 696.0 bits: 136.0 E(32554): 1.9e-32
Smith-Waterman score: 540; 46.2% identity (75.4% similar) in 195 aa overlap (33-224:24-215)
10 20 30 40 50 60
pF1KE0 DPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAALS
: : .:.. : :.. .::::: :::::.
CCDS23 MALVPYEETTEFGLQKFHKPLATFSFANHTIQIRQDW-RHLGVAAVVWDAAIV
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 LCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANVPA
: .:.: :..::....:::::::.:::.::: :. ::::: .::: ...:::::.:
CCDS23 LSTYLEMGAVELRGRSAVELGAGTGLVGIVAALLGAHVTITDRKVALEFLKSNVQANLPP
60 70 80 90 100 110
130 140 150 160 170
pF1KE0 GGQAQ--VRALSWGIDHHVF-PANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLA
:.. :. :.:: . : :...::.:::::.::: :: :: ::.::: :..: ::
CCDS23 HIQTKTVVKELTWGQNLGSFSPGEFDLILGADIIYLEETFTDLLQTLEHLCSNHSVILLA
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 SKMRKEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHREPRPA
..: :. .. : .: ..: .. .. : ...:.::.:..:. .
CCDS23 CRIRYER--DNNFLAMLERQFTVRKVHYDPEKDVHIYEAQKRNQKEDL
180 190 200 210
>>CCDS32003.1 METTL21C gene_id:196541|Hs108|chr13 (264 aa)
initn: 192 init1: 108 opt: 303 Z-score: 391.3 bits: 79.8 E(32554): 1.8e-15
Smith-Waterman score: 303; 32.8% identity (65.7% similar) in 201 aa overlap (26-217:65-258)
10 20 30 40 50
pF1KE0 MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAAR
::... .. : :. ..: ... : .:
CCDS32 KDSTGGVLEESNKIEPSLHSLQKFVPTDYASYTQE-HYRFAGKEIVIQESIESY---GAV
40 50 60 70 80 90
60 70 80 90 100 110
pF1KE0 VWDAALSLCNYFE--SQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQ
:: .:..::.:.: .....:. :..:.::: :.:.:.:.. :..:: :::: .: ..:
CCDS32 VWPGAMALCQYLEEHAEELNFQDAKILEIGAGPGLVSIVASILGAQVTATDLPDVLGNLQ
100 110 120 130 140 150
120 130 140 150 160
pF1KE0 GNVQANVP--AGGQAQVRALSWGID-HHVFPAN---YDLVLGADIVYLEPTFPLLLGTLQ
:. :. .. .:. : :: : . :: . :: ::..:.:: . . :: :.
CCDS32 YNLLKNTLQCTAHLPEVKELVWGEDLDKNFPKSAFYYDYVLASDVVYHHYFLDKLLTTMV
160 170 180 190 200 210
170 180 190 200 210 220
pF1KE0 HLCRPHGTIYL-ASKMRKEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHREPRPA
.: .: ::. : :.:.: .:. : . : :. : . . .:....
CCDS32 YLSQP-GTVLLWANKFR--FSTDYEFLDKFKQVFDTTLLAEYPESSVKLFKGILKWD
220 230 240 250 260
>>CCDS9696.2 VCPKMT gene_id:79609|Hs108|chr14 (229 aa)
initn: 256 init1: 128 opt: 286 Z-score: 370.5 bits: 75.8 E(32554): 2.6e-14
Smith-Waterman score: 298; 32.8% identity (60.3% similar) in 204 aa overlap (37-224:25-226)
10 20 30 40 50 60
pF1KE0 DPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAALSLCNY
: :: . : : ::. :::::. : .:
CCDS96 MADTLESSLEDPLRSFVRVLEKRDGTVLRLQQY--SSGGVGCVVWDAAIVLSKY
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 FESQNVDFRG------KKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANV
.:. . . : ..:.:::.::: ::..:: :.::..::: . .. :.. :
CCDS96 LETPEFSGDGAHALSRRSVLELGSGTGAVGLMAATLGADVVVTDLEELQDLLKMNINMNK
60 70 80 90 100 110
130 140 150 160 170
pF1KE0 P-AGGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTI---
. :..:...:.:: . . ::. :..: :: .: : .. :: ::. . . :
CCDS96 HLVTGSVQAKVLKWGEEIEGFPSPPDFILMADCIYYEESLEPLLKTLKDISGFETCIICC
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 YLASKMRKEHGTESFFQHLLPQHFQLE---LAQRDED---ENVNIYRARHREPRPA
: : :. :. . .:: :..: : ..::. :...: :... .
CCDS96 YEQRTMGKNPEIEKKYFELLQLDFDFEKIPLEKHDEEYRSEDIHIIYIRKKKSKFPS
180 190 200 210 220
>>CCDS41951.1 VCPKMT gene_id:79609|Hs108|chr14 (194 aa)
initn: 246 init1: 118 opt: 273 Z-score: 355.0 bits: 72.7 E(32554): 1.9e-13
Smith-Waterman score: 273; 37.1% identity (65.0% similar) in 140 aa overlap (37-169:25-162)
10 20 30 40 50 60
pF1KE0 DPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAALSLCNY
: :: . : : ::. :::::. : .:
CCDS41 MADTLESSLEDPLRSFVRVLEKRDGTVLRLQQY--SSGGVGCVVWDAAIVLSKY
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 FESQNVDFRG------KKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANV
.:. . . : ..:.:::.::: ::..:: :.::..::: . .. :.. :
CCDS41 LETPEFSGDGAHALSRRSVLELGSGTGAVGLMAATLGADVVVTDLEELQDLLKMNINMNK
60 70 80 90 100 110
130 140 150 160 170
pF1KE0 P-AGGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLA
. :..:...:.:: . . ::. :..: :: .: : .. :: ::. .
CCDS41 HLVTGSVQAKVLKWGEEIEGFPSPPDFILMADCIYYEESLEPLLKTLKDISGFETCIICC
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 SKMRKEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHREPRPA
CCDS41 YEQRTMGKNPEIEKKYFEKFPS
180 190
>>CCDS82562.1 METTL21A gene_id:151194|Hs108|chr2 (90 aa)
initn: 205 init1: 205 opt: 231 Z-score: 306.4 bits: 62.6 E(32554): 9.5e-11
Smith-Waterman score: 231; 52.9% identity (79.4% similar) in 68 aa overlap (33-100:24-90)
10 20 30 40 50 60
pF1KE0 DPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAALS
: : .:.. : :.. .::::: :::::.
CCDS82 MALVPYEETTEFGLQKFHKPLATFSFANHTIQIRQDW-RHLGVAAVVWDAAIV
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 LCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANVPA
: .:.: :..::....:::::::.:::.::: :: .
CCDS82 LSTYLEMGAVELRGRSAVELGAGTGLVGIVAALLGGGI
60 70 80 90
130 140 150 160 170 180
pF1KE0 GGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLASKM
226 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 07:22:54 2016 done: Thu Nov 3 07:22:54 2016
Total Scan time: 2.240 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]