Result of FASTA (ccds) for
pFN21AE3912
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3912, 416 aa
1>>>pF1KE3912 416 - 416 aa - 416 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8530+/-0.000841; mu= 11.2430+/- 0.051
mean_var=125.0800+/-25.200, 0's: 0 Z-trim(110.9): 25 B-trim: 0 in 0/54
Lambda= 0.114678
statistics sampled from 11935 (11954) to 11935 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.732), E-opt: 0.2 (0.367), width: 16
Scan time: 3.080
The best scores are: opt bits E(32554)
CCDS33702.1 MKRN2 gene_id:23609|Hs108|chr3 ( 416) 2927 495.2 4.7e-140
CCDS63545.1 MKRN2 gene_id:23609|Hs108|chr3 ( 373) 2563 435.0 5.8e-122
CCDS5860.1 MKRN1 gene_id:23608|Hs108|chr7 ( 482) 1038 182.8 6.3e-46
CCDS10013.1 MKRN3 gene_id:7681|Hs108|chr15 ( 507) 900 159.9 4.9e-39
CCDS47725.1 MKRN1 gene_id:23608|Hs108|chr7 ( 329) 609 111.7 1.1e-24
>>CCDS33702.1 MKRN2 gene_id:23609|Hs108|chr3 (416 aa)
initn: 2927 init1: 2927 opt: 2927 Z-score: 2628.0 bits: 495.2 E(32554): 4.7e-140
Smith-Waterman score: 2927; 99.8% identity (100.0% similar) in 416 aa overlap (1-416:1-416)
10 20 30 40 50 60
pF1KE3 MSTKQITCRYFMHGVCREGSQCLFSHDLANSKPSTICKYYQKGYCAYGTRCRYDHTRPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MSTKQITCRYFMHGVCREGSQCLFSHDLANSKPSTICKYYQKGYCAYGTRCRYDHTRPSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 AAGGAVGTMAHSVPSPAFHSPHPPSEVTASIVKTNSHEPGKREKRTLVLRDRNLSGMAER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 AAGGAVGTMAHSVPSPAFHSPHPPSEVTASIVKTNSHEPGKREKRTLVLRDRNLSGMAER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 KTQPSMVSNPGSCSDPQPSPEMKPHSYLDAIRSGLDDVEASSSYSNEQQLCPYAAAGECR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 KTQPSMVSNPGSCSDPQPSPEMKPHSYLDAIRSGLDDVEASSSYSNEQQLCPYAAAGECR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 FGDACVYLHGEVCEICRLQVLHPFDPEQRKAHEKICMLTFEHEMEKAFAFQANQDKVCSI
::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
CCDS33 FGDACVYLHGEVCEICRLQVLHPFDPEQRKAHEKICMLTFEHEMEKAFAFQASQDKVCSI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 CMEVILEKASASERRFGILSNCNHTYCLSCIRQWRCAKQFENPIIKSCPECRVISEFVIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 CMEVILEKASASERRFGILSNCNHTYCLSCIRQWRCAKQFENPIIKSCPECRVISEFVIP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SVYWVEDQNKKNELIEAFKQGMGKKACKYFEQGKGTCPFGSKCLYRHAYPDGRLAEPEKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 SVYWVEDQNKKNELIEAFKQGMGKKACKYFEQGKGTCPFGSKCLYRHAYPDGRLAEPEKP
310 320 330 340 350 360
370 380 390 400 410
pF1KE3 RKQLSSQGTVRFFNSVRLWDFIENRESRHVPNNEDVDMTELGDLFMHLSGVESSEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 RKQLSSQGTVRFFNSVRLWDFIENRESRHVPNNEDVDMTELGDLFMHLSGVESSEP
370 380 390 400 410
>>CCDS63545.1 MKRN2 gene_id:23609|Hs108|chr3 (373 aa)
initn: 2563 init1: 2563 opt: 2563 Z-score: 2303.2 bits: 435.0 E(32554): 5.8e-122
Smith-Waterman score: 2563; 99.7% identity (100.0% similar) in 366 aa overlap (51-416:8-373)
30 40 50 60 70 80
pF1KE3 QCLFSHDLANSKPSTICKYYQKGYCAYGTRCRYDHTRPSAAAGGAVGTMAHSVPSPAFHS
::::::::::::::::::::::::::::::
CCDS63 MSTKQITCRYDHTRPSAAAGGAVGTMAHSVPSPAFHS
10 20 30
90 100 110 120 130 140
pF1KE3 PHPPSEVTASIVKTNSHEPGKREKRTLVLRDRNLSGMAERKTQPSMVSNPGSCSDPQPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 PHPPSEVTASIVKTNSHEPGKREKRTLVLRDRNLSGMAERKTQPSMVSNPGSCSDPQPSP
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE3 EMKPHSYLDAIRSGLDDVEASSSYSNEQQLCPYAAAGECRFGDACVYLHGEVCEICRLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 EMKPHSYLDAIRSGLDDVEASSSYSNEQQLCPYAAAGECRFGDACVYLHGEVCEICRLQV
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE3 LHPFDPEQRKAHEKICMLTFEHEMEKAFAFQANQDKVCSICMEVILEKASASERRFGILS
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
CCDS63 LHPFDPEQRKAHEKICMLTFEHEMEKAFAFQASQDKVCSICMEVILEKASASERRFGILS
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE3 NCNHTYCLSCIRQWRCAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 NCNHTYCLSCIRQWRCAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQ
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE3 GMGKKACKYFEQGKGTCPFGSKCLYRHAYPDGRLAEPEKPRKQLSSQGTVRFFNSVRLWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 GMGKKACKYFEQGKGTCPFGSKCLYRHAYPDGRLAEPEKPRKQLSSQGTVRFFNSVRLWD
280 290 300 310 320 330
390 400 410
pF1KE3 FIENRESRHVPNNEDVDMTELGDLFMHLSGVESSEP
::::::::::::::::::::::::::::::::::::
CCDS63 FIENRESRHVPNNEDVDMTELGDLFMHLSGVESSEP
340 350 360 370
>>CCDS5860.1 MKRN1 gene_id:23608|Hs108|chr7 (482 aa)
initn: 1285 init1: 975 opt: 1038 Z-score: 938.0 bits: 182.8 E(32554): 6.3e-46
Smith-Waterman score: 1329; 46.8% identity (73.3% similar) in 408 aa overlap (3-408:56-451)
10 20 30
pF1KE3 MSTKQITCRYFMHGVCREGSQCLFSHDLANSK
:::.::::::::::.::..: .::::..:
CCDS58 ASPTPIPTVTAPSLGAGGGGGGSDGSGGGWTKQVTCRYFMHGVCKEGDNCRYSHDLSDSP
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE3 PSTICKYYQKGYCAYGTRCRYDHTRPSAAAGGAVGTMAHSVPSPAFHSPHPPSEVTASIV
:..:::.:.::: :: ::::.:..: :..: . : : : : ... .:
CCDS58 YSVVCKYFQRGYCIYGDRCRYEHSKPLKQEE-ATATELTTKSSLAASSSL--SSIVGPLV
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE3 KTNSHEPGKREKRTLVLRDRNLSGMAERKTQPSMVSNPGSCSDPQPSPEMKPHSYLDAIR
. :. : .:.. .. .: . . .: . :. :: : :..
CCDS58 EMNTGEAESRNSNFATVG----AGSEDWVNAIEFVPGQPYCGRTAPSCTEAP---LQGSV
150 160 170 180 190
160 170 180 190 200 210
pF1KE3 SGLDDVEASSSYSNEQQLCPYAAAGECRFGDACVYLHGEVCEICRLQVLHPFDPEQRKAH
. .. . ... ...:::::::.::::.:. ::::::. :..: ::::::.: ::. :
CCDS58 TKEESEKEQTAVETKKQLCPYAAVGECRYGENCVYLHGDSCDMCGLQVLHPMDAAQRSQH
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE3 EKICMLTFEHEMEKAFAFQANQDKVCSICMEVILEKASASERRFGILSNCNHTYCLSCIR
: :. . :..:: .:: : ..: ::.:::::. :::. :::::::::::::::::.:::
CCDS58 IKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIR
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE3 QWRCAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQGMGKKACKYFEQ
.:: :::::. :::::::::. :.::::: ::::....:..:: .:..:..:::.::..
CCDS58 KWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLILKYKEAMSNKACRYFDE
320 330 340 350 360 370
340 350 360 370 380 390
pF1KE3 GKGTCPFGSKCLYRHAYPDGRLAEPEKPRKQLSSQGTVRFFNSVRLWDFIENRESRHVPN
:.:.::::..:.:.::::::: ::.. . ::. .. : ..:..::.::. . .
CCDS58 GRGSCPFGGNCFYKHAYPDGRREEPQRQKVGTSSRYRAQRRN--HFWELIEERENSNPFD
380 390 400 410 420 430
400 410
pF1KE3 N--EDVDMTELGDLFMHLSGVESSEP
: :.: :::.... :
CCDS58 NDEEEVVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDLDL
440 450 460 470 480
>>CCDS10013.1 MKRN3 gene_id:7681|Hs108|chr15 (507 aa)
initn: 1057 init1: 864 opt: 900 Z-score: 814.3 bits: 159.9 E(32554): 4.9e-39
Smith-Waterman score: 1005; 41.9% identity (67.2% similar) in 360 aa overlap (3-360:96-433)
10 20 30
pF1KE3 MSTKQITCRYFMHGVCREGSQCLFSHDLANSK
:::: :::..:: :.:: .: .::::.. :
CCDS10 HLRRGGLRPAPASGGGAWPSPLPSRSSGIWTKQIICRYYIHGQCKEGENCRYSHDLSGRK
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE3 PSTICKYYQKGYCAYGTRCRYDHTRPSAAAGGAVGTMAHSVPSPAFHSPHPPSEVTASI-
.: . : . :.:.:::. .: :: : . ::. . :.
CCDS10 MAT-----EGGV-----------SPPGASAGGGPSTAAHIEPPTQEVAEAPPAASSLSLP
130 140 150 160
100 110 120 130 140 150
pF1KE3 VKTNSHEPGKREKRTLVLRDRNLSGMAERKTQPSMVS-NPGSCSDPQPSPEMKPHSYLDA
: .. : : : . ::. .: : .. . . :: :: : .:
CCDS10 VIGSAAERGFFEAERDNA-DRGAAGGAGVESWADAIEFVPG-----QPYRGRWVASAPEA
170 180 190 200 210 220
160 170 180 190 200 210
pF1KE3 IRSGLDDVEASSSYSNEQQLCPYAAAGECRFGDACVYLHGEVCEICRLQVLHPFDPEQRK
.. . . . . .. ..: ::. : : :..:.::::..:..: ::.:::.: ::.
CCDS10 PLQSSETERKQMAVGSGLRFCYYASRGVCFRGESCMYLHGDICDMCGLQTLHPMDAAQRE
230 240 250 260 270 280
220 230 240 250 260 270
pF1KE3 AHEKICMLTFEHEMEKAFAFQANQDKVCSICMEVILEKASASERRFGILSNCNHTYCLSC
: . :. . :..:: .:: : ..::::.:::::. :::. ..:::::::::::..:. :
CCDS10 EHMRACIEAHEKDMELSFAVQRGMDKVCGICMEVVYEKANPNDRRFGILSNCNHSFCIRC
290 300 310 320 330 340
280 290 300 310 320 330
pF1KE3 IRQWRCAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQGMGKKACKYF
::.:: :.:::: :.::::.::: ::.:::: .:::....:..::. .:..:..:::.::
CCDS10 IRRWRSARQFENRIVKSCPQCRVTSELVIPSEFWVEEEEEKQKLIQQYKEAMSNKACRYF
350 360 370 380 390 400
340 350 360 370 380 390
pF1KE3 EQGKGTCPFGSKCLYRHAYPDGRLAEPEKPRKQLSSQGTVRFFNSVRLWDFIENRESRHV
.:.:.::::. :.:.: ::.: :: :
CCDS10 AEGRGNCPFGDTCFYKHEYPEGWGDEPPGPGGGSFSAYWHQLVEPVRMGEGNMLYKSIKK
410 420 430 440 450 460
>>CCDS47725.1 MKRN1 gene_id:23608|Hs108|chr7 (329 aa)
initn: 910 init1: 600 opt: 609 Z-score: 556.8 bits: 111.7 E(32554): 1.1e-24
Smith-Waterman score: 900; 46.8% identity (70.4% similar) in 284 aa overlap (3-286:56-329)
10 20 30
pF1KE3 MSTKQITCRYFMHGVCREGSQCLFSHDLANSK
:::.::::::::::.::..: .::::..:
CCDS47 ASPTPIPTVTAPSLGAGGGGGGSDGSGGGWTKQVTCRYFMHGVCKEGDNCRYSHDLSDSP
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE3 PSTICKYYQKGYCAYGTRCRYDHTRPSAAAGGAVGTMAHSVPSPAFHSPHPPSEVTASIV
:..:::.:.::: :: ::::.:..: :..: . : : : : ... .:
CCDS47 YSVVCKYFQRGYCIYGDRCRYEHSKPLKQEE-ATATELTTKSSLAASSSL--SSIVGPLV
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE3 KTNSHEPGKREKRTLVLRDRNLSGMAERKTQPSMVSNPGSCSDPQPSPEMKPHSYLDAIR
. :. : .:.. .. .: . . .: . :. :: : :..
CCDS47 EMNTGEAESRNSNFATVG----AGSEDWVNAIEFVPGQPYCGRTAPSCTEAP---LQGSV
150 160 170 180 190
160 170 180 190 200 210
pF1KE3 SGLDDVEASSSYSNEQQLCPYAAAGECRFGDACVYLHGEVCEICRLQVLHPFDPEQRKAH
. .. . ... ...:::::::.::::.:. ::::::. :..: ::::::.: ::. :
CCDS47 TKEESEKEQTAVETKKQLCPYAAVGECRYGENCVYLHGDSCDMCGLQVLHPMDAAQRSQH
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE3 EKICMLTFEHEMEKAFAFQANQDKVCSICMEVILEKASASERRFGILSNCNHTYCLSCIR
: :. . :..:: .:: : ..: ::.:::::. :::. :::::::::::::::::.:::
CCDS47 IKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIR
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE3 QWRCAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQGMGKKACKYFEQ
.:: :::::. :::
CCDS47 KWRSAKQFESKIIK
320
416 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 09:01:06 2016 done: Sun Nov 6 09:01:07 2016
Total Scan time: 3.080 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]