Result of FASTA (omim) for
pFN21AE3657
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3657, 414 aa
1>>>pF1KE3657 414 - 414 aa - 414 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8053+/-0.000417; mu= 14.4419+/- 0.026
mean_var=72.5357+/-14.391, 0's: 0 Z-trim(111.9): 12 B-trim: 19 in 1/50
Lambda= 0.150591
statistics sampled from 20672 (20682) to 20672 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.616), E-opt: 0.2 (0.242), width: 16
Scan time: 6.370
The best scores are: opt bits E(85289)
NP_055031 (OMIM: 601838) inositol-tetrakisphosphat ( 414) 2732 603.1 4.2e-172
NP_001136065 (OMIM: 601838) inositol-tetrakisphosp ( 414) 2732 603.1 4.2e-172
XP_016876751 (OMIM: 601838) PREDICTED: inositol-te ( 476) 2478 547.9 1.9e-155
NP_001136066 (OMIM: 601838) inositol-tetrakisphosp ( 314) 1970 437.5 2.3e-122
XP_016876753 (OMIM: 601838) PREDICTED: inositol-te ( 284) 1874 416.6 3.9e-116
XP_016876752 (OMIM: 601838) PREDICTED: inositol-te ( 284) 1874 416.6 3.9e-116
>>NP_055031 (OMIM: 601838) inositol-tetrakisphosphate 1- (414 aa)
initn: 2732 init1: 2732 opt: 2732 Z-score: 3210.8 bits: 603.1 E(85289): 4.2e-172
Smith-Waterman score: 2732; 100.0% identity (100.0% similar) in 414 aa overlap (1-414:1-414)
10 20 30 40 50 60
pF1KE3 MQTFLKGKRVGYWLSEKKIKKLNFQAFAELCRKRGMEVVQLNLSRPIEEQGPLDVIIHKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MQTFLKGKRVGYWLSEKKIKKLNFQAFAELCRKRGMEVVQLNLSRPIEEQGPLDVIIHKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TDVILEADQNDSQSLELVHRFQEYIDAHPETIVLDPLPAIRTLLDRSKSYELIRKIEAYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TDVILEADQNDSQSLELVHRFQEYIDAHPETIVLDPLPAIRTLLDRSKSYELIRKIEAYM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EDDRICSPPFMELTSLCGDDTMRLLEKNGLTFPFICKTRVAHGTNSHEMAIVFNQEGLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EDDRICSPPFMELTSLCGDDTMRLLEKNGLTFPFICKTRVAHGTNSHEMAIVFNQEGLNA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 IQPPCVVQNFINHNAVLYKVFVVGESYTVVQRPSLKNFSAGTSDRESIFFNSHNVSKPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IQPPCVVQNFINHNAVLYKVFVVGESYTVVQRPSLKNFSAGTSDRESIFFNSHNVSKPES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SSVLTELDKIEGVFERPSDEVIRELSRALRQALGVSLFGIDIIINNQTGQHAVIDINAFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SSVLTELDKIEGVFERPSDEVIRELSRALRQALGVSLFGIDIIINNQTGQHAVIDINAFP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 GYEGVSEFFTDLLNHIATVLQGQSTAMAATGDVALLRHSKLLAEPAGGLVGERTCSASPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GYEGVSEFFTDLLNHIATVLQGQSTAMAATGDVALLRHSKLLAEPAGGLVGERTCSASPG
310 320 330 340 350 360
370 380 390 400 410
pF1KE3 CCGSMMGQDAPWKAEADAGGTAKLPHQRLGCNAGVSPSFQQHCVASLATKASSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CCGSMMGQDAPWKAEADAGGTAKLPHQRLGCNAGVSPSFQQHCVASLATKASSQ
370 380 390 400 410
>>NP_001136065 (OMIM: 601838) inositol-tetrakisphosphate (414 aa)
initn: 2732 init1: 2732 opt: 2732 Z-score: 3210.8 bits: 603.1 E(85289): 4.2e-172
Smith-Waterman score: 2732; 100.0% identity (100.0% similar) in 414 aa overlap (1-414:1-414)
10 20 30 40 50 60
pF1KE3 MQTFLKGKRVGYWLSEKKIKKLNFQAFAELCRKRGMEVVQLNLSRPIEEQGPLDVIIHKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQTFLKGKRVGYWLSEKKIKKLNFQAFAELCRKRGMEVVQLNLSRPIEEQGPLDVIIHKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TDVILEADQNDSQSLELVHRFQEYIDAHPETIVLDPLPAIRTLLDRSKSYELIRKIEAYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDVILEADQNDSQSLELVHRFQEYIDAHPETIVLDPLPAIRTLLDRSKSYELIRKIEAYM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EDDRICSPPFMELTSLCGDDTMRLLEKNGLTFPFICKTRVAHGTNSHEMAIVFNQEGLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDDRICSPPFMELTSLCGDDTMRLLEKNGLTFPFICKTRVAHGTNSHEMAIVFNQEGLNA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 IQPPCVVQNFINHNAVLYKVFVVGESYTVVQRPSLKNFSAGTSDRESIFFNSHNVSKPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQPPCVVQNFINHNAVLYKVFVVGESYTVVQRPSLKNFSAGTSDRESIFFNSHNVSKPES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SSVLTELDKIEGVFERPSDEVIRELSRALRQALGVSLFGIDIIINNQTGQHAVIDINAFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSVLTELDKIEGVFERPSDEVIRELSRALRQALGVSLFGIDIIINNQTGQHAVIDINAFP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 GYEGVSEFFTDLLNHIATVLQGQSTAMAATGDVALLRHSKLLAEPAGGLVGERTCSASPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYEGVSEFFTDLLNHIATVLQGQSTAMAATGDVALLRHSKLLAEPAGGLVGERTCSASPG
310 320 330 340 350 360
370 380 390 400 410
pF1KE3 CCGSMMGQDAPWKAEADAGGTAKLPHQRLGCNAGVSPSFQQHCVASLATKASSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CCGSMMGQDAPWKAEADAGGTAKLPHQRLGCNAGVSPSFQQHCVASLATKASSQ
370 380 390 400 410
>>XP_016876751 (OMIM: 601838) PREDICTED: inositol-tetrak (476 aa)
initn: 2478 init1: 2478 opt: 2478 Z-score: 2911.6 bits: 547.9 E(85289): 1.9e-155
Smith-Waterman score: 2478; 96.9% identity (98.2% similar) in 389 aa overlap (26-414:88-476)
10 20 30 40 50
pF1KE3 MQTFLKGKRVGYWLSEKKIKKLNFQAFAELCRKRGMEVVQLNLSRPIEEQGPLDV
:: .. . .:.:::::::::::::::
XP_016 QTGQRGRSRPLRRPVGPPEEFSGSESRDSGAFLHFVSPVTLPLVRLNLSRPIEEQGPLDV
60 70 80 90 100 110
60 70 80 90 100 110
pF1KE3 IIHKLTDVILEADQNDSQSLELVHRFQEYIDAHPETIVLDPLPAIRTLLDRSKSYELIRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIHKLTDVILEADQNDSQSLELVHRFQEYIDAHPETIVLDPLPAIRTLLDRSKSYELIRK
120 130 140 150 160 170
120 130 140 150 160 170
pF1KE3 IEAYMEDDRICSPPFMELTSLCGDDTMRLLEKNGLTFPFICKTRVAHGTNSHEMAIVFNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEAYMEDDRICSPPFMELTSLCGDDTMRLLEKNGLTFPFICKTRVAHGTNSHEMAIVFNQ
180 190 200 210 220 230
180 190 200 210 220 230
pF1KE3 EGLNAIQPPCVVQNFINHNAVLYKVFVVGESYTVVQRPSLKNFSAGTSDRESIFFNSHNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGLNAIQPPCVVQNFINHNAVLYKVFVVGESYTVVQRPSLKNFSAGTSDRESIFFNSHNV
240 250 260 270 280 290
240 250 260 270 280 290
pF1KE3 SKPESSSVLTELDKIEGVFERPSDEVIRELSRALRQALGVSLFGIDIIINNQTGQHAVID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKPESSSVLTELDKIEGVFERPSDEVIRELSRALRQALGVSLFGIDIIINNQTGQHAVID
300 310 320 330 340 350
300 310 320 330 340 350
pF1KE3 INAFPGYEGVSEFFTDLLNHIATVLQGQSTAMAATGDVALLRHSKLLAEPAGGLVGERTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INAFPGYEGVSEFFTDLLNHIATVLQGQSTAMAATGDVALLRHSKLLAEPAGGLVGERTC
360 370 380 390 400 410
360 370 380 390 400 410
pF1KE3 SASPGCCGSMMGQDAPWKAEADAGGTAKLPHQRLGCNAGVSPSFQQHCVASLATKASSQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SASPGCCGSMMGQDAPWKAEADAGGTAKLPHQRLGCNAGVSPSFQQHCVASLATKASSQ
420 430 440 450 460 470
>>NP_001136066 (OMIM: 601838) inositol-tetrakisphosphate (314 aa)
initn: 1970 init1: 1970 opt: 1970 Z-score: 2318.0 bits: 437.5 E(85289): 2.3e-122
Smith-Waterman score: 1970; 100.0% identity (100.0% similar) in 301 aa overlap (1-301:1-301)
10 20 30 40 50 60
pF1KE3 MQTFLKGKRVGYWLSEKKIKKLNFQAFAELCRKRGMEVVQLNLSRPIEEQGPLDVIIHKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQTFLKGKRVGYWLSEKKIKKLNFQAFAELCRKRGMEVVQLNLSRPIEEQGPLDVIIHKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TDVILEADQNDSQSLELVHRFQEYIDAHPETIVLDPLPAIRTLLDRSKSYELIRKIEAYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDVILEADQNDSQSLELVHRFQEYIDAHPETIVLDPLPAIRTLLDRSKSYELIRKIEAYM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EDDRICSPPFMELTSLCGDDTMRLLEKNGLTFPFICKTRVAHGTNSHEMAIVFNQEGLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDDRICSPPFMELTSLCGDDTMRLLEKNGLTFPFICKTRVAHGTNSHEMAIVFNQEGLNA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 IQPPCVVQNFINHNAVLYKVFVVGESYTVVQRPSLKNFSAGTSDRESIFFNSHNVSKPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQPPCVVQNFINHNAVLYKVFVVGESYTVVQRPSLKNFSAGTSDRESIFFNSHNVSKPES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SSVLTELDKIEGVFERPSDEVIRELSRALRQALGVSLFGIDIIINNQTGQHAVIDINAFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSVLTELDKIEGVFERPSDEVIRELSRALRQALGVSLFGIDIIINNQTGQHAVIDINAFP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 GYEGVSEFFTDLLNHIATVLQGQSTAMAATGDVALLRHSKLLAEPAGGLVGERTCSASPG
:
NP_001 GDCQVCFIEGWKTD
310
>>XP_016876753 (OMIM: 601838) PREDICTED: inositol-tetrak (284 aa)
initn: 1874 init1: 1874 opt: 1874 Z-score: 2205.9 bits: 416.6 E(85289): 3.9e-116
Smith-Waterman score: 1874; 100.0% identity (100.0% similar) in 284 aa overlap (131-414:1-284)
110 120 130 140 150 160
pF1KE3 RTLLDRSKSYELIRKIEAYMEDDRICSPPFMELTSLCGDDTMRLLEKNGLTFPFICKTRV
::::::::::::::::::::::::::::::
XP_016 MELTSLCGDDTMRLLEKNGLTFPFICKTRV
10 20 30
170 180 190 200 210 220
pF1KE3 AHGTNSHEMAIVFNQEGLNAIQPPCVVQNFINHNAVLYKVFVVGESYTVVQRPSLKNFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHGTNSHEMAIVFNQEGLNAIQPPCVVQNFINHNAVLYKVFVVGESYTVVQRPSLKNFSA
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE3 GTSDRESIFFNSHNVSKPESSSVLTELDKIEGVFERPSDEVIRELSRALRQALGVSLFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTSDRESIFFNSHNVSKPESSSVLTELDKIEGVFERPSDEVIRELSRALRQALGVSLFGI
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE3 DIIINNQTGQHAVIDINAFPGYEGVSEFFTDLLNHIATVLQGQSTAMAATGDVALLRHSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIIINNQTGQHAVIDINAFPGYEGVSEFFTDLLNHIATVLQGQSTAMAATGDVALLRHSK
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE3 LLAEPAGGLVGERTCSASPGCCGSMMGQDAPWKAEADAGGTAKLPHQRLGCNAGVSPSFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLAEPAGGLVGERTCSASPGCCGSMMGQDAPWKAEADAGGTAKLPHQRLGCNAGVSPSFQ
220 230 240 250 260 270
410
pF1KE3 QHCVASLATKASSQ
::::::::::::::
XP_016 QHCVASLATKASSQ
280
>>XP_016876752 (OMIM: 601838) PREDICTED: inositol-tetrak (284 aa)
initn: 1874 init1: 1874 opt: 1874 Z-score: 2205.9 bits: 416.6 E(85289): 3.9e-116
Smith-Waterman score: 1874; 100.0% identity (100.0% similar) in 284 aa overlap (131-414:1-284)
110 120 130 140 150 160
pF1KE3 RTLLDRSKSYELIRKIEAYMEDDRICSPPFMELTSLCGDDTMRLLEKNGLTFPFICKTRV
::::::::::::::::::::::::::::::
XP_016 MELTSLCGDDTMRLLEKNGLTFPFICKTRV
10 20 30
170 180 190 200 210 220
pF1KE3 AHGTNSHEMAIVFNQEGLNAIQPPCVVQNFINHNAVLYKVFVVGESYTVVQRPSLKNFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHGTNSHEMAIVFNQEGLNAIQPPCVVQNFINHNAVLYKVFVVGESYTVVQRPSLKNFSA
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE3 GTSDRESIFFNSHNVSKPESSSVLTELDKIEGVFERPSDEVIRELSRALRQALGVSLFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTSDRESIFFNSHNVSKPESSSVLTELDKIEGVFERPSDEVIRELSRALRQALGVSLFGI
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE3 DIIINNQTGQHAVIDINAFPGYEGVSEFFTDLLNHIATVLQGQSTAMAATGDVALLRHSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIIINNQTGQHAVIDINAFPGYEGVSEFFTDLLNHIATVLQGQSTAMAATGDVALLRHSK
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE3 LLAEPAGGLVGERTCSASPGCCGSMMGQDAPWKAEADAGGTAKLPHQRLGCNAGVSPSFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLAEPAGGLVGERTCSASPGCCGSMMGQDAPWKAEADAGGTAKLPHQRLGCNAGVSPSFQ
220 230 240 250 260 270
410
pF1KE3 QHCVASLATKASSQ
::::::::::::::
XP_016 QHCVASLATKASSQ
280
414 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 20:23:01 2016 done: Sun Nov 6 20:23:02 2016
Total Scan time: 6.370 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]