Result of FASTA (ccds) for
pFN21AE0425
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0425, 373 aa
1>>>pF1KE0425 373 - 373 aa - 373 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3764+/-0.000953; mu= 15.7455+/- 0.057
mean_var=63.9724+/-12.879, 0's: 0 Z-trim(104.6): 30 B-trim: 0 in 0/50
Lambda= 0.160353
statistics sampled from 7977 (7990) to 7977 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.628), E-opt: 0.2 (0.245), width: 16
Scan time: 2.410
The best scores are: opt bits E(32554)
CCDS14717.1 NSDHL gene_id:50814|Hs108|chrX ( 373) 2485 583.8 8.1e-167
CCDS42205.1 SDR42E1 gene_id:93517|Hs108|chr16 ( 393) 514 127.9 1.5e-29
CCDS903.1 HSD3B1 gene_id:3283|Hs108|chr1 ( 373) 324 83.9 2.5e-16
CCDS902.1 HSD3B2 gene_id:3284|Hs108|chr1 ( 372) 303 79.0 7.3e-15
CCDS10698.1 HSD3B7 gene_id:80270|Hs108|chr16 ( 369) 286 75.1 1.1e-13
>>CCDS14717.1 NSDHL gene_id:50814|Hs108|chrX (373 aa)
initn: 2485 init1: 2485 opt: 2485 Z-score: 3108.4 bits: 583.8 E(32554): 8.1e-167
Smith-Waterman score: 2485; 100.0% identity (100.0% similar) in 373 aa overlap (1-373:1-373)
10 20 30 40 50 60
pF1KE0 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME
310 320 330 340 350 360
370
pF1KE0 RTVQSFRHLRRVK
:::::::::::::
CCDS14 RTVQSFRHLRRVK
370
>>CCDS42205.1 SDR42E1 gene_id:93517|Hs108|chr16 (393 aa)
initn: 503 init1: 171 opt: 514 Z-score: 643.7 bits: 127.9 E(32554): 1.5e-29
Smith-Waterman score: 604; 33.8% identity (65.3% similar) in 346 aa overlap (34-360:5-348)
10 20 30 40 50 60
pF1KE0 AVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYA
..: . . ::::..: .. : :
CCDS42 MDPKRSQKESVLITGGSGYFGFRLGCALNQNGVH
10 20 30
70 80 90 100 110
pF1KE0 VNVFDIQQGFDN-PQ-VRFFLGDLCSRQDLYPALKG--VNTVFHCASPPPSSN---NKEL
: .:::.. .. :. ..:. ::. .:. :.. :. ::: :: :. :..:
CCDS42 VILFDISSPAQTIPEGIKFIQGDIRHLSDVEKAFQDADVTCVFHIASYGMSGREQLNRNL
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE0 FYRVNYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYA---MKPIDYYT
. .:: :: :....:.. : .:. ::. .::: : :.:: :.::: ..: :.:.
CCDS42 IKEVNVRGTDNILQVCQRRRVPRLVYTSTFNVIFGGQVIRNGDESLPYLPLHLHP-DHYS
100 110 120 130 140 150
180 190 200 210 220
pF1KE0 ETKILQERAVLGAN----DPEKNFLTT-AIRPHGIFGPRDPQLVPILIEAARNGKMKFVI
.:: . :. :: :: : . : : :.:: ::.:: . . .: .. ..: .:::
CCDS42 RTKSIAEQKVLEANATPLDRGDGVLRTCALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVY
160 170 180 190 200 210
230 240 250 260 270 280
pF1KE0 GNGKNLVDFTFVENVVHGHILAAEQLSRDS--TLGGKAFHITNDEPIPFWTFLSRILTGL
:. ..::.:. :.:.:..::::.: : :. .:. . :.. .:. . :. .. ::
CCDS42 GDPRSLVEFVHVDNLVQAHILASEALRADKGHIASGQPYFISDGRPVNNFEFFRPLVEGL
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE0 NYEAPKYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKA
.: :. ..: ..: .:.: .. .... . ..:: .: .: .:. ::.: :.:::
CCDS42 GYTFPSTRLPLTLVYCFAFLTEMVHFILGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKE
280 290 300 310 320 330
350 360 370
pF1KE0 MGY--QPLVTMDDAMERTVQSFRHLRRVK
.:: ::. ...:.:
CCDS42 LGYKAQPF-DLQEAVEWFKAHGHGRSSGSRDSECFVWDGLLVFLLIIAVLMWLPSSVILS
340 350 360 370 380 390
>>CCDS903.1 HSD3B1 gene_id:3283|Hs108|chr1 (373 aa)
initn: 206 init1: 70 opt: 324 Z-score: 406.5 bits: 83.9 E(32554): 2.5e-16
Smith-Waterman score: 378; 27.2% identity (58.9% similar) in 353 aa overlap (40-364:6-355)
10 20 30 40 50 60
pF1KE0 RDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGY--AVNVF
: : :..:::::.... :. . . :.
CCDS90 MTGWSCLVTGAGGFLGQRIIRLLVKEKELKEIRVL
10 20 30
70 80 90 100 110
pF1KE0 D------IQQGFDNPQVRFFL----GDLCSRQDLYPALKGVNTVFH--CASPPPSSNNKE
: ... :.. : . : ::. .. : : . :....: : . ...:
CCDS90 DKAFGPELREEFSKLQNKTKLTVLEGDILDEPFLKRACQDVSVIIHTACIIDVFGVTHRE
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE0 LFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI----FEGVDIKNGTEDLPYAMKPIDY
.. :: ::. ..:.: .:.: .: ::: : .. . :.:: :. :
CCDS90 SIMNVNVKGTQLLLEACVQASVPVFIYTSSIEVAGPNSYKEI-IQNGHEEEPLENTWPAP
100 110 120 130 140 150
180 190 200 210 220
pF1KE0 YTETKILQERAVLGANDPE-KN---FLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFV
: ..: : :.:::.:: . :: . : :.:: :.: . : . :: :. .
CCDS90 YPHSKKLAEKAVLAANGWNLKNGGTLYTCALRPMYIYGEGSRFLSASINEALNNNGILSS
160 170 180 190 200 210
230 240 250 260 270 280
pF1KE0 IGNGKNLVDFTFVENVVHGHILAAEQLS---RDSTLGGKAFHITNDEPIPFWTFLSRILT
.:. .. :. ..: ::. .:::: . :. . .. :. ..:..: : . :. :.
CCDS90 VGKFST-VNPVYVGNVAWAHILALRALQDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLS
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE0 ---GLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCE
:: .. .. .: . :....:: .. ... :. .: :. :.:... .: .
CCDS90 KEFGLRLDS-RWSFPLSLMYWIGFLLEIVSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYK
280 290 300 310 320 330
350 360 370
pF1KE0 RAKKAMGYQPLVTMDDAMERTVQSFRHLRRVK
.:.. ..:.:: . ..: ..::.
CCDS90 KAQRDLAYKPLYSWEEAKQKTVEWVGSLVDRHKETLKSKTQ
340 350 360 370
>>CCDS902.1 HSD3B2 gene_id:3284|Hs108|chr1 (372 aa)
initn: 285 init1: 127 opt: 303 Z-score: 380.3 bits: 79.0 E(32554): 7.3e-15
Smith-Waterman score: 407; 29.0% identity (58.9% similar) in 355 aa overlap (40-364:5-354)
10 20 30 40 50 60
pF1KE0 RDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDI
: : :..:.:::..:. :. . .. .
CCDS90 MGWSCLVTGAGGLLGQRIVRLLVEEKELKEIRAL
10 20 30
70 80 90 100 110
pF1KE0 QQGFDNPQVRFFLGDLCSRQDLY---------PALK----GVNTVFH--CASPPPSSNNK
...: :..: .. : .: : : :: :..:.: : . ...
CCDS90 DKAF-RPELREEFSKLQNRTKLTVLEGDILDEPFLKRACQDVSVVIHTACIIDVFGVTHR
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE0 ELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI----FEGVDIKNGTEDLPYAMKPID
: .. :: ::. ..:.: .:.: .: ::: : .. . :.:: :. :
CCDS90 ESIMNVNVKGTQLLLEACVQASVPVFIYTSSIEVAGPNSYKEI-IQNGHEEEPLENTWPT
100 110 120 130 140 150
180 190 200 210 220
pF1KE0 YYTETKILQERAVLGANDPE-KN---FLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKF
: .: : :.:::.:: . :: . : :.:: :.: : : . :: :. .
CCDS90 PYPYSKKLAEKAVLAANGWNLKNGDTLYTCALRPTYIYGEGGPFLSASINEALNNNGILS
160 170 180 190 200 210
230 240 250 260 270 280
pF1KE0 VIGNGKNLVDFTFVENVVHGHILAAEQLSRDS----TLGGKAFHITNDEPIPFWTFLSRI
.:. .. :. ..: ::. .:::: . : :: .. :. ..:..: : . :. :
CCDS90 SVGKFST-VNPVYVGNVAWAHILALRAL-RDPKKAPSVRGQFYYISDDTPHQSYDNLNYI
220 230 240 250 260 270
290 300 310 320 330
pF1KE0 LT---GLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYS
:. :: .. .. .: . :....:: .. ...::. . :: :. :.:... .:
CCDS90 LSKEFGLRLDS-RWSLPLTLMYWIGFLLEVVSFLLSPIYSYQPPFNRHTVTLSNSVFTFS
280 290 300 310 320
340 350 360 370
pF1KE0 CERAKKAMGYQPLVTMDDAMERTVQSFRHLRRVK
..:.. ..:.:: . ..: ..::.
CCDS90 YKKAQRDLAYKPLYSWEEAKQKTVEWVGSLVDRHKETLKSKTQ
330 340 350 360 370
>>CCDS10698.1 HSD3B7 gene_id:80270|Hs108|chr16 (369 aa)
initn: 427 init1: 174 opt: 286 Z-score: 359.1 bits: 75.1 E(32554): 1.1e-13
Smith-Waterman score: 446; 30.0% identity (55.8% similar) in 353 aa overlap (34-363:6-358)
10 20 30 40 50 60
pF1KE0 AVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYA
: : : :: ::::.:.:..:: :
CCDS10 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPR
10 20 30
70 80 90 100 110
pF1KE0 VN---VFDIQQG-----FDNPQVRF--FLGDLCSRQDLYPALKGVNTVFHCASPPP--SS
.. ::: . : . . :: . ::. . ... :. :...:.: :. .
CCDS10 LGELRVFDQHLGPWLEELKTGPVRVTAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGR
40 50 60 70 80 90
120 130 140 150 160
pF1KE0 NNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI---FEGVDIKNGTEDLPYAMKP
. . ...:: ::.::::.: ..:.. :. ::: :. .: . :.:: ::
CCDS10 ASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVH
100 110 120 130 140 150
170 180 190 200 210 220
pF1KE0 IDYYTETKILQERAVLGANDPEKN----FLTTAIRPHGIFGPRDPQLVPILIEAARNGKM
: .: : : :: :: . ..: :.:: ::.: . . .. : :
CCDS10 RHPYPCSKALAEWLVLEANGRKVRGGLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGW
160 170 180 190 200 210
230 240 250 260 270 280
pF1KE0 KFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDSTL-GGKAFHITNDEPI-PFWTFLSRI
: .. ..: ::. :.:::..: . .:: ::... . : . : ..
CCDS10 LFRAIPASVEHGRVYVGNVAWMHVLAARELEQRATLMGGQVYFCYDGSPYRSYEDFNMEF
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE0 L--TGLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSC
: :: . . .:::. .:: : .:: .. :.. : ..:. .:.:.: :
CCDS10 LGPCGLRLVGARPLLPYWLLVFLAALNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVST
280 290 300 310 320 330
350 360 370
pF1KE0 ERAKKAMGYQPLVTMDDAMERTVQSFRHLRRVK
..:.. .::.:: . .:. ::.
CCDS10 DKAQRHFGYEPLFSWEDSRTRTILWVQAATGSAQ
340 350 360
373 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 10:36:40 2016 done: Thu Nov 3 10:36:40 2016
Total Scan time: 2.410 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]