Result of FASTA (ccds) for
pFN21AE0384
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0384, 489 aa
1>>>pF1KE0384 489 - 489 aa - 489 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.9921+/-0.000887; mu= 3.7021+/- 0.054
mean_var=223.3433+/-45.403, 0's: 0 Z-trim(114.3): 10 B-trim: 148 in 1/54
Lambda= 0.085820
statistics sampled from 14832 (14841) to 14832 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.764), E-opt: 0.2 (0.456), width: 16
Scan time: 3.940
The best scores are: opt bits E(32554)
CCDS33647.1 NPTXR gene_id:23467|Hs108|chr22 ( 500) 3277 418.2 1e-116
CCDS5657.1 NPTX2 gene_id:4885|Hs108|chr7 ( 431) 1422 188.5 1.2e-47
CCDS32762.1 NPTX1 gene_id:4884|Hs108|chr17 ( 432) 1266 169.2 8.1e-42
CCDS48004.1 SVEP1 gene_id:79987|Hs108|chr9 (3571) 457 69.7 5.9e-11
>>CCDS33647.1 NPTXR gene_id:23467|Hs108|chr22 (500 aa)
initn: 3277 init1: 3277 opt: 3277 Z-score: 2209.0 bits: 418.2 E(32554): 1e-116
Smith-Waterman score: 3277; 100.0% identity (100.0% similar) in 489 aa overlap (1-489:12-500)
10 20 30 40
pF1KE0 MLAFLGAVICIIASVPLAASPARALPGGADNASVASGAAASPGPQRSLS
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MKFLAVLLAAGMLAFLGAVICIIASVPLAASPARALPGGADNASVASGAAASPGPQRSLS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 ALHGAGGSAGPPALPGAPAASAHPLPPGPLFSRFLCTPLAAACPSGAQQGDAAGAAPGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 ALHGAGGSAGPPALPGAPAASAHPLPPGPLFSRFLCTPLAAACPSGAQQGDAAGAAPGER
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 EELLLLQSTAEQLRQTALQQEARIRADQDTIRELTGKLGRCESGLPRGLQGAGPRRDTMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 EELLLLQSTAEQLRQTALQQEARIRADQDTIRELTGKLGRCESGLPRGLQGAGPRRDTMA
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 DGPWDSPALILELEDAVRALRDRIDRLEQELPARVNLSAAPAPVSAVPTGLHSKMDQLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 DGPWDSPALILELEDAVRALRDRIDRLEQELPARVNLSAAPAPVSAVPTGLHSKMDQLEG
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE0 QLLAQVLALEKERVALSHSSRRQRQEVEKELDVLQGRVAELEHGSSAYSPPDAFKISIPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 QLLAQVLALEKERVALSHSSRRQRQEVEKELDVLQGRVAELEHGSSAYSPPDAFKISIPI
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE0 RNNYMYARVRKALPELYAFTACMWLRSRSSGTGQGTPFSYSVPGQANEIVLLEAGHEPME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 RNNYMYARVRKALPELYAFTACMWLRSRSSGTGQGTPFSYSVPGQANEIVLLEAGHEPME
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE0 LLINDKVAQLPLSLKDNGWHHICIAWTTRDGLWSAYQDGELQGSGENLAAWHPIKPHGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LLINDKVAQLPLSLKDNGWHHICIAWTTRDGLWSAYQDGELQGSGENLAAWHPIKPHGIL
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE0 ILGQEQDTLGGRFDATQAFVGDIAQFNLWDHALTPAQVLGIANCTAPLLGNVLPWEDKLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 ILGQEQDTLGGRFDATQAFVGDIAQFNLWDHALTPAQVLGIANCTAPLLGNVLPWEDKLV
430 440 450 460 470 480
470 480
pF1KE0 EAFGGATKAAFDVCKGRAKA
::::::::::::::::::::
CCDS33 EAFGGATKAAFDVCKGRAKA
490 500
>>CCDS5657.1 NPTX2 gene_id:4885|Hs108|chr7 (431 aa)
initn: 1387 init1: 798 opt: 1422 Z-score: 968.7 bits: 188.5 E(32554): 1.2e-47
Smith-Waterman score: 1422; 51.5% identity (77.4% similar) in 429 aa overlap (66-486:12-427)
40 50 60 70 80
pF1KE0 SGAAASPGPQRSLSALHGAGGSAGPPALPGAPAASAHPLP-PGPLFSRFLCTPLA-----
: ::.:. : :: :::.:: :
CCDS56 MLALLAASVALAVAAGAQDSPAPG---SRFVCTALPPEAVH
10 20 30
90 100 110 120 130 140
pF1KE0 AACPSGAQQGDAAGAAPGEREELLLLQSTAEQLRQTALQQEARIRADQDTIRELTGKLGR
:.:: :. :.: . .::: .... :::.:..::. . :....::::::::.:
CCDS56 AGCPLPAMP--MQGGAQSPEEEL---RAAVLQLRETVVQQKETLGAQREAIRELTGKLAR
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE0 CESGLPRG-LQGAGPR-RDTMADGPWDSPALILELEDAVRALRDRIDRLEQELPARVNLS
:: :: : .::: .:::.: : : .. .: ....:.::.. ::..: : :. .
CCDS56 CE-GLAGGKARGAGATGKDTMGDLPRDPGHVVEQLSRSLQTLKDRLESLEHQLRANVSNA
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE0 AAPAPVSAVPTGLHSKMDQLEGQLLAQVLALEKERVALSHSSRRQRQEVEKELDVLQGRV
. :. : :.... .:: ::: .: :: :. : . . .::..:. :..: ::
CCDS56 GLPGDFREV---LQQRLGELERQLLRKVAELEDEKSLLHNETSAHRQKTESTLNALLQRV
160 170 180 190 200
270 280 290 300 310 320
pF1KE0 AELEHGSSAYSPPDAFKISIPIRNNYMYARVRKALPELYAFTACMWLRSRSSGTGQGTPF
.:::.:.::.. :::::.:.:.:.::.:....:.:::::::: :.:::: :.. : ::::
CCDS56 TELERGNSAFKSPDAFKVSLPLRTNYLYGKIKKTLPELYAFTICLWLRS-SASPGIGTPF
210 220 230 240 250 260
330 340 350 360 370 380
pF1KE0 SYSVPGQANEIVLLEAGHEPMELLINDKVAQLPLSLKDNGWHHICIAWTTRDGLWSAYQD
::.::::::::::.: :..:.::::::::::::: ..:. :::::..::::::.: :.::
CCDS56 SYAVPGQANEIVLIEWGNNPIELLINDKVAQLPLFVSDGKWHHICVTWTTRDGMWEAFQD
270 280 290 300 310 320
390 400 410 420 430 440
pF1KE0 GELQGSGENLAAWHPIKPHGILILGQEQDTLGGRFDATQAFVGDIAQFNLWDHALTPAQV
:: :.::::: :::::: :.:::::::::.::::::::::::...:::.::..: ..
CCDS56 GEKLGTGENLAPWHPIKPGGVLILGQEQDTVGGRFDATQAFVGELSQFNIWDRVLRAQEI
330 340 350 360 370 380
450 460 470 480
pF1KE0 LGIANCTAPLLGNVLPWEDKLVEAFGGATKAAFDVCKGRAKA
..::::.. . ::..:: :. :..::::.: ..:. :
CCDS56 VNIANCSTNMPGNIIPWVDNNVDVFGGASKWPVETCEERLLDL
390 400 410 420 430
>>CCDS32762.1 NPTX1 gene_id:4884|Hs108|chr17 (432 aa)
initn: 1128 init1: 690 opt: 1266 Z-score: 864.3 bits: 169.2 E(32554): 8.1e-42
Smith-Waterman score: 1266; 48.7% identity (74.8% similar) in 421 aa overlap (77-484:26-429)
50 60 70 80 90 100
pF1KE0 SLSALHGAGGSAGPPALPGAPAASAHPLPPGPLFSRFLCTPLAAACPSGAQQGDAAGAAP
:: .::.:: . : :.. :. ::
CCDS32 MPAGRAARTCALLALCLLGAGAQDFGP--TRFICTSV----PVDADMCAASVAAG
10 20 30 40
110 120 130 140 150
pF1KE0 GEREELLLLQSTAEQLRQTALQQEARIRADQDTIRELTGKLGRCES--------GLPR--
: .: :.:.. :::.:.:::. : ....::::::.::::::: : :
CCDS32 GAEE----LRSSVLQLRETVLQQKETILSQKETIRELTAKLGRCESQSTLDPGAGEARAG
50 60 70 80 90 100
160 170 180 190 200 210
pF1KE0 -GLQGAGPRRDTMADGPWDSPALIL-ELEDAVRALRDRIDRLEQELPARVNLSAAPAPVS
: . : ..::.: : : .: .....:. :.. ::: .:.: :. ..
CCDS32 GGRKQPGSGKNTMGDLSRTPAAETLSQLGQTLQSLKTRLENLEQY--SRLNSSSQTNSLK
110 120 130 140 150 160
220 230 240 250 260 270
pF1KE0 AVPTGLHSKMDQLEGQLLAQVLALEKERVALSHSSRRQRQEVEKELDVLQGRVAELEHGS
. :.::.:.:: :.:..: .::. . . ... ..: ..: : :. :..:::.:.
CCDS32 DL---LQSKIDELERQVLSRVNTLEEGKGG-PRNDTEERVKIETALTSLHQRISELEKGQ
170 180 190 200 210
280 290 300 310 320 330
pF1KE0 SAYSPPDAFKISIPIRNNYMYARVRKALPELYAFTACMWLRSRSSGTGQGTPFSYSVPGQ
. : : :....:.:.:::::.:.:.:::.::::.::::.: :. : ::::::.::::
CCDS32 KDNRPGDKFQLTFPLRTNYMYAKVKKSLPEMYAFTVCMWLKS-SATPGVGTPFSYAVPGQ
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE0 ANEIVLLEAGHEPMELLINDKVAQLPLSLKDNGWHHICIAWTTRDGLWSAYQDGELQGSG
:::.::.: :..:::.:::::::.::. ..:. :::::..::::::.: ::::: :::
CCDS32 ANELVLIEWGNNPMEILINDKVAKLPFVINDGKWHHICVTWTTRDGVWEAYQDGTQGGSG
280 290 300 310 320 330
400 410 420 430 440 450
pF1KE0 ENLAAWHPIKPHGILILGQEQDTLGGRFDATQAFVGDIAQFNLWDHALTPAQVLGIANC-
:::: .:::::.:.:.:::::::::: :::::::::..:.::.::. :::..: ..:.:
CCDS32 ENLAPYHPIKPQGVLVLGQEQDTLGGGFDATQAFVGELAHFNIWDRKLTPGEVYNLATCS
340 350 360 370 380 390
460 470 480
pF1KE0 TAPLLGNVLPWEDKLVEAFGGATKAAFDVCKGRAKA
: : :::. : .. .: .::::: .:..:.
CCDS32 TKALSGNVIAWAESHIEIYGGATKWTFEACRQIN
400 410 420 430
>>CCDS48004.1 SVEP1 gene_id:79987|Hs108|chr9 (3571 aa)
initn: 376 init1: 331 opt: 457 Z-score: 310.2 bits: 69.7 E(32554): 5.9e-11
Smith-Waterman score: 457; 39.0% identity (69.2% similar) in 195 aa overlap (283-473:1426-1617)
260 270 280 290 300 310
pF1KE0 RQEVEKELDVLQGRVAELEHGSSAYSPPDAFKISIPIRNNYMYARVRKALPELYAFTACM
:.... . . : :. . :: :.:.: .
CCDS48 ATCVDELNSYSCKCQPGFSGKRCETEQSTGFNLDFEVSGIYGYVMLDGMLPSLHALTCTF
1400 1410 1420 1430 1440 1450
320 330 340 350 360 370
pF1KE0 WLRSRSSGTGQGTPFSYSVPGQANEIVLLEAGHEPMELLIN--DKVAQLPLSLKDNGWHH
:..: :. . :::.::.: . ... .:: . .. : .: .:... : :..:. :::
CCDS48 WMKS-SDDMNYGTPISYAVDNGSDNTLLL-TDYNGWVLYVNGREKITNCP-SVNDGRWHH
1460 1470 1480 1490 1500 1510
380 390 400 410 420 430
pF1KE0 ICIAWTTRDGLWSAYQDGELQGSGENLAAWHPIKPHGILILGQEQDTLGGRFDATQAFVG
: :.::. .:.:..: ::.:. .: .:.. :: : :.:::::: : :. ...:::
CCDS48 IAITWTSANGIWKVYIDGKLSDGGAGLSVGLPIPGGGALVLGQEQDKKGEGFSPAESFVG
1520 1530 1540 1550 1560 1570
440 450 460 470 480
pF1KE0 DIAQFNLWDHALTPAQVLGIA-NCTAPLL-GNVLPWEDKLVEAFGGATKAAFDVCKGRAK
.:.:.::::..:.: :: ..: .: : :::: : : : :
CCDS48 SISQLNLWDYVLSPQQVKSLATSCPEELSKGNVLAWPDFLSGIVGKVKIDSKSIFCSDCP
1580 1590 1600 1610 1620 1630
pF1KE0 A
CCDS48 RLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGV
1640 1650 1660 1670 1680 1690
489 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 13:02:25 2016 done: Thu Nov 3 13:02:26 2016
Total Scan time: 3.940 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]