Result of FASTA (ccds) for
pFN21AE1199
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1199, 368 aa
1>>>pF1KE1199 368 - 368 aa - 368 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.9077+/-0.00106; mu= -15.5351+/- 0.063
mean_var=529.3993+/-110.985, 0's: 0 Z-trim(118.1): 60 B-trim: 490 in 1/52
Lambda= 0.055742
statistics sampled from 18960 (19020) to 18960 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.847), E-opt: 0.2 (0.584), width: 16
Scan time: 3.740
The best scores are: opt bits E(32554)
CCDS46024.1 MEF2B gene_id:100271849|Hs108|chr19 ( 368) 2610 223.7 2.1e-58
CCDS12394.1 MEF2B gene_id:4207|Hs108|chr19 ( 365) 1809 159.2 5e-39
CCDS53978.1 MEF2A gene_id:4205|Hs108|chr15 ( 497) 658 66.8 4.6e-11
CCDS81920.1 MEF2A gene_id:4205|Hs108|chr15 ( 505) 654 66.5 5.8e-11
CCDS45362.1 MEF2A gene_id:4205|Hs108|chr15 ( 499) 652 66.3 6.5e-11
CCDS54878.1 MEF2C gene_id:4208|Hs108|chr5 ( 483) 648 66.0 7.9e-11
>>CCDS46024.1 MEF2B gene_id:100271849|Hs108|chr19 (368 aa)
initn: 2610 init1: 2610 opt: 2610 Z-score: 1162.2 bits: 223.7 E(32554): 2.1e-58
Smith-Waterman score: 2610; 100.0% identity (100.0% similar) in 368 aa overlap (1-368:1-368)
10 20 30 40 50 60
pF1KE1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DMDRVLLKYTEYSEPHESRTNTDILETLKRRGIGLDGPELEPDEGPEEPGEKFRRLAGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 DMDRVLLKYTEYSEPHESRTNTDILETLKRRGIGLDGPELEPDEGPEEPGEKFRRLAGEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 PGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 PGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGPALRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 EEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGPALRRL
310 320 330 340 350 360
pF1KE1 PLADGWPR
::::::::
CCDS46 PLADGWPR
>>CCDS12394.1 MEF2B gene_id:4207|Hs108|chr19 (365 aa)
initn: 1824 init1: 1790 opt: 1809 Z-score: 814.1 bits: 159.2 E(32554): 5e-39
Smith-Waterman score: 1830; 80.1% identity (83.0% similar) in 352 aa overlap (1-336:1-346)
10 20 30 40 50 60
pF1KE1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DMDRVLLKYTEYSEPHESRTNTDILETLKRRGIGLDGPELEPDEGPEEPGEKFRRLAGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 DMDRVLLKYTEYSEPHESRTNTDILETLKRRGIGLDGPELEPDEGPEEPGEKFRRLAGEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT
190 200 210 220 230 240
250 260 270 280
pF1KE1 PGPPLGSFPFLPGGPP------EYGLGDPPPPPGLLQPPTLA---------PWQPSRGDG
:::::::::::::::: . .: :: .:: : : :.
CCDS12 PGPPLGSFPFLPGGPPVGAEAWARRVPQPAAPPR--RPPQSASSLSASLRPPGAPATFLR
250 260 270 280 290
290 300 310 320 330 340
pF1KE1 P-PAVSSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLA
: : :.:. .:: ::: : :: . : ::. .: : :
CCDS12 PSPIPCSSPGPWQSLCGLGPPCAGCPWPTAGPG----RRSPGGTSPERSPGTARARGDPT
300 310 320 330 340 350
350 360
pF1KE1 RSLAEPLRPGPALRRLPLADGWPR
CCDS12 SLQASSEKTQQ
360
>>CCDS53978.1 MEF2A gene_id:4205|Hs108|chr15 (497 aa)
initn: 662 init1: 548 opt: 658 Z-score: 312.1 bits: 66.8 E(32554): 4.6e-11
Smith-Waterman score: 658; 41.0% identity (63.9% similar) in 332 aa overlap (1-315:1-314)
10 20 30 40 50 60
pF1KE1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST
::::::::.::.:.::::::::::::::::::::::::::::::::::::.:.:::::::
CCDS53 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 DMDRVLLKYTEYSEPHESRTNTDILETLKRRGI-GLDGPELEPDEGPEEP--GEKFRRLA
:::.::::::::.::::::::.::.:::...:. : ..:. . : . : ..: .:
CCDS53 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDAD-DYFEHSPLSEDRFSKL-
70 80 90 100 110
120 130 140 150 160 170
pF1KE1 GEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKA
.: .: . : . :..: :. .. : .:..:. . :..: :: :.
CCDS53 NEDSDFIFKR-----GPPGLP-PQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTL
120 130 140 150 160 170
180 190 200 210 220
pF1KE1 GPPGLVHPLFSPSHLTSKTPPPLYLPTEGR------RSDL--PGGLAG--PRG-GLNTSR
... : . : . . : :. : .:: :.: :: : : :. .::
CCDS53 TDSSMLSPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNG-AGSSPVGNGFVNSR
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 SLYSGLQNPCSTATPGP--PLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGD
. .: . .. . : : : : : : . :... : .. ::. :.:
CCDS53 A-SPNLIGATGANSLGKVMPTKSPP--PPGGGNLGMNSRKPDLRVVIPPS------SKGM
240 250 260 270 280
290 300 310 320 330 340
pF1KE1 GPPAVSSQPSGGRSLGEEGPPTRGASPPT-PPVSIKSERLSPAPGGPGDFPKTFPYPLLL
:: ... :.... . :. ... :. ::
CCDS53 MPPLNTQRISSSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQG
290 300 310 320 330 340
350 360
pF1KE1 ARSLAEPLRPGPALRRLPLADGWPR
CCDS53 FNSPGMLSLGQVSAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRD
350 360 370 380 390 400
>>CCDS81920.1 MEF2A gene_id:4205|Hs108|chr15 (505 aa)
initn: 662 init1: 548 opt: 654 Z-score: 310.3 bits: 66.5 E(32554): 5.8e-11
Smith-Waterman score: 654; 38.6% identity (59.6% similar) in 386 aa overlap (1-366:1-365)
10 20 30 40 50 60
pF1KE1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST
::::::::.::.:.::::::::::::::::::::::::::::::::::::.:.:::::::
CCDS81 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 DMDRVLLKYTEYSEPHESRTNTDILETLKRRGI-GLDGPELEPDEGPEEP--GEKFRRLA
:::.::::::::.::::::::.::.:::...:. : ..:. . : . : ..: .:
CCDS81 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDAD-DYFEHSPLSEDRFSKL-
70 80 90 100 110
120 130 140 150 160 170
pF1KE1 GEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKA
.: .: . : . :..: :. .. : .:..:. . :..: :: :.
CCDS81 NEDSDFIFKR-----GPPGLP-PQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTL
120 130 140 150 160 170
180 190 200 210 220
pF1KE1 GPPGLVHPLFSPSHLTSKTPPPLYLPTEGR------RSDL--PGGLAG--PRG-GLNTSR
... : . : . . : :. : .:: :.: :: : : :. .::
CCDS81 TDSSMLSPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNG-AGSSPVGNGFVNSR
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 SLYSGLQNPCSTATPGP--PLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGD
. .: . .. . : : : : : : . :... : .. ::. :.:
CCDS81 A-SPNLIGATGANSLGKVMPTKSPP--PPGGGNLGMNSRKPDLRVVIPPS------SKGM
240 250 260 270 280
290 300 310 320 330 340
pF1KE1 GPPAVSSQPSGGRSLGEEGPPTRGASPP--TPPVSIKSERLSPAPGGPGDFPKTF--PYP
:: .: . :. . . :. : :: ::. . : : . .: .. :
CCDS81 MPP-LSEEEE--LELNTQRISSSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYS
290 300 310 320 330
350 360
pF1KE1 LLLARSLAEPLRPGPALRRLPLADGWPR
: : : .:.. : ...:
CCDS81 LTSADLSALQGFNSPGMLSLGQVSAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNIS
340 350 360 370 380 390
>>CCDS45362.1 MEF2A gene_id:4205|Hs108|chr15 (499 aa)
initn: 603 init1: 530 opt: 652 Z-score: 309.5 bits: 66.3 E(32554): 6.5e-11
Smith-Waterman score: 652; 41.1% identity (63.4% similar) in 333 aa overlap (1-315:1-316)
10 20 30 40 50 60
pF1KE1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST
::::::::.::.:.::::::::::::::::::::::::::::::::::::.:.:::::::
CCDS45 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 DMDRVLLKYTEYSEPHESRTNTDILETL-KRRGIGLDGPELEPDEG---PEEPGEKFRRL
:::.::::::::.::::::::.::.:.: :.. : :.:. :: . . ::....
CCDS45 DMDKVLLKYTEYNEPHESRTNSDIVEALNKKEHRGCDSPD--PDTSYVLTPHTEEKYKKI
70 80 90 100 110
120 130 140 150 160 170
pF1KE1 AGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPK
.: : . : . ::..: :. .. : .:..:. . :..: :: :.
CCDS45 -NEEFDNMM---RNHKIAPGLP-PQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASST
120 130 140 150 160 170
180 190 200 210 220
pF1KE1 AGPPGLVHPLFSPSHLTSKTPPPLYLPTEGR------RSDL--PGGLAG--PRG-GLNTS
... : . : . . : :. : .:: :.: :: : : :. .:
CCDS45 LTDSSMLSPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNG-AGSSPVGNGFVNS
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 RSLYSGLQNPCSTATPGP--PLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRG
:. .: . .. . : : : : : : . :... : .. ::. :.:
CCDS45 RA-SPNLIGATGANSLGKVMPTKSPP--PPGGGNLGMNSRKPDLRVVIPPS------SKG
240 250 260 270 280
290 300 310 320 330 340
pF1KE1 DGPPAVSSQPSGGRSLGEEGPPTRGASPPT-PPVSIKSERLSPAPGGPGDFPKTFPYPLL
:: ... :.... . :. ... :. ::
CCDS45 MMPPLNTQRISSSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQ
290 300 310 320 330 340
350 360
pF1KE1 LARSLAEPLRPGPALRRLPLADGWPR
CCDS45 GFNSPGMLSLGQVSAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPR
350 360 370 380 390 400
>>CCDS54878.1 MEF2C gene_id:4208|Hs108|chr5 (483 aa)
initn: 647 init1: 547 opt: 648 Z-score: 307.9 bits: 66.0 E(32554): 7.9e-11
Smith-Waterman score: 648; 40.9% identity (64.0% similar) in 328 aa overlap (1-315:1-314)
10 20 30 40 50 60
pF1KE1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST
::::::::.::.:.::::::::::::::::::::::::::::::::::::.:.:::::::
CCDS54 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYAST
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 DMDRVLLKYTEYSEPHESRTNTDILETLKRRGI-GLDGPELEPDEGPEEPGEKFRRLAGE
:::.::::::::.::::::::.::.:::...:. : :.:. :: ..: . . :
CCDS54 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCDSPD--PDADDSALNKKENK-GCE
70 80 90 100 110
120 130 140 150 160
pF1KE1 GGDP----AL-PRPRLYPAAPAMPSPDVVYG----ALPPPGCDPSGLGEALPAQSRPS-P
. :: :: :: . ... . :.:::. . . ..:..:. :
CCDS54 SPDPDSSYALTPRTEEKYKKINEEFDNMIKSHKIPAVPPPNFE---MPVSIPVSSHNSLV
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 FRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYL--PTEGRRSDLPGGLAGPRGGLNTSRS
. . . : :.:. :: :: .. : . :. : . : :: .: ... .
CCDS54 YSNPVSSLGNPNLL-PLAHPSLQRNSMSPGVTHRPPSAGNTGGLMGGDLTSGAGTSAGNG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 LYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPP
. ..: ..:: :.. . .:: ..:: : : .: : :. . :
CCDS54 YGNPRNSPGLLVSPGN-LNK-NMQAKSPPPMNLGMNNRKPDLR---VLIP--PGSKNTMP
240 250 260 270 280
290 300 310 320 330 340
pF1KE1 AVSSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARSL
.:... ....: . :. ... :: :
CCDS54 SVNQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTEYSLSSADLSSLSGF
290 300 310 320 330 340
368 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 21:00:24 2016 done: Sun Nov 6 21:00:25 2016
Total Scan time: 3.740 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]