Result of FASTA (ccds) for
pFN21AE0314
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0314, 716 aa
1>>>pF1KE0314 716 - 716 aa - 716 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.6296+/-0.00103; mu= 6.0070+/- 0.062
mean_var=194.8743+/-38.841, 0's: 0 Z-trim(110.3): 25 B-trim: 58 in 1/52
Lambda= 0.091875
statistics sampled from 11532 (11544) to 11532 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.355), width: 16
Scan time: 4.330
The best scores are: opt bits E(32554)
CCDS56120.1 FAM161A gene_id:84140|Hs108|chr2 ( 716) 4686 634.1 2.2e-181
CCDS42687.2 FAM161A gene_id:84140|Hs108|chr2 ( 660) 3553 483.9 3.3e-136
CCDS9822.2 FAM161B gene_id:145483|Hs108|chr14 ( 710) 760 113.7 9.7e-25
>>CCDS56120.1 FAM161A gene_id:84140|Hs108|chr2 (716 aa)
initn: 4686 init1: 4686 opt: 4686 Z-score: 3369.9 bits: 634.1 E(32554): 2.2e-181
Smith-Waterman score: 4686; 99.7% identity (99.9% similar) in 716 aa overlap (1-716:1-716)
10 20 30 40 50 60
pF1KE0 MATSHRVAKLVASSLQTPVNPITGARVAQYEREDPLKALAAAEAILEDEEEEKVAQPAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MATSHRVAKLVASSLQTPVNPITGARVAQYEREDPLKALAAAEAILEDEEEEKVAQPAGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SADLNTSFSGVDEHAPISYEDFVNFPDIHHSNEEYFKKVEELKAAHMETMAKLEKMYQDK
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
CCDS56 SADLNTSFSGVDEHAPISYEDFVNFPDIHHSNEEYFKKVEELKAAHIETMAKLEKMYQDK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LHLKEVQPVVIREDSLSDSSRSVSGKNSYHPVSLMTSFSEPDLGQSSSLYVSSSEEELPN
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
CCDS56 LHLKEVQPVVIREDSLSDSSRSVSEKNSYHPVSLMTSFSEPDLGQSSSLYVSSSEEELPN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LEKEYPRKNRMMTYAKELINNMWTDFCVEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LEKEYPRKNRMMTYAKELINNMWTDFCVEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 PFQMMIREQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 PFQMMIREQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 KQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRFKARPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 KQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRFKARPI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 PRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVKLKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 PRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVKLKC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 KHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHASIKREKILADIEADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 KHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHASIKREKILADIEADE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 ENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVRRSLEEKKMLEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 ENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVRRSLEEKKMLEEE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 RNRILTKQKQRMKELQKLLTTRAKAYDSHQSLAQISKSRVKCLRKSEKERMREYQRELEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 RNRILTKQKQRMKELQKLLTTRAKAYDSHQSLAQISKSRVKCLRKSEKERMREYQRELEE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 REEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLEYFNNQET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 REEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLEYFNNQET
610 620 630 640 650 660
670 680 690 700 710
pF1KE0 KSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEKSVEESH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 KSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEKSVEESH
670 680 690 700 710
>>CCDS42687.2 FAM161A gene_id:84140|Hs108|chr2 (660 aa)
initn: 3587 init1: 3528 opt: 3553 Z-score: 2558.8 bits: 483.9 E(32554): 3.3e-136
Smith-Waterman score: 4220; 91.9% identity (92.0% similar) in 716 aa overlap (1-716:1-660)
10 20 30 40 50 60
pF1KE0 MATSHRVAKLVASSLQTPVNPITGARVAQYEREDPLKALAAAEAILEDEEEEKVAQPAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MATSHRVAKLVASSLQTPVNPITGARVAQYEREDPLKALAAAEAILEDEEEEKVAQPAGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 SADLNTSFSGVDEHAPISYEDFVNFPDIHHSNEEYFKKVEELKAAHMETMAKLEKMYQDK
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
CCDS42 SADLNTSFSGVDEHAPISYEDFVNFPDIHHSNEEYFKKVEELKAAHIETMAKLEKMYQDK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LHLKEVQPVVIREDSLSDSSRSVSGKNSYHPVSLMTSFSEPDLGQSSSLYVSSSEEELPN
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
CCDS42 LHLKEVQPVVIREDSLSDSSRSVSEKNSYHPVSLMTSFSEPDLGQSSSLYVSSSEEELPN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LEKEYPRKNRMMTYAKELINNMWTDFCVEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LEKEYPRKNRMMTYAKELINNMWTDFCVEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 PFQMMIREQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PFQMMIREQKKKEESMKSKSDIEMVHKALKKQEEDPEYKKKFRANPVPASVFLPLYHDLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 KQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRFKARPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 KQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNRFKARPI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 PRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVKLKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGCRNPRCPEQAVKLKC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 KHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHASIKREKILADIEADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 KHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHASIKREKILADIEADE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 ENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVRRSLEEKKMLEEE
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 ENLKETRWPYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVR------------
490 500 510 520
550 560 570 580 590 600
pF1KE0 RNRILTKQKQRMKELQKLLTTRAKAYDSHQSLAQISKSRVKCLRKSEKERMREYQRELEE
::::::::::::::::
CCDS42 --------------------------------------------KSEKERMREYQRELEE
530 540
610 620 630 640 650 660
pF1KE0 REEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLEYFNNQET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 REEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLEYFNNQET
550 560 570 580 590 600
670 680 690 700 710
pF1KE0 KSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEKSVEESH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 KSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEKSVEESH
610 620 630 640 650 660
>>CCDS9822.2 FAM161B gene_id:145483|Hs108|chr14 (710 aa)
initn: 703 init1: 327 opt: 760 Z-score: 557.6 bits: 113.7 E(32554): 9.7e-25
Smith-Waterman score: 832; 34.8% identity (62.6% similar) in 492 aa overlap (232-708:228-704)
210 220 230 240 250 260
pF1KE0 MWTDFCVEDYIRCKDTGFHAAEKRRKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSD
:. .::::.::.: .:: .:: : . : ..
CCDS98 LNNLPSNIPRPQTQPPSGSRPPSQHRSVSSWASSITVPRPFRMTLREARKKAEWLGSPAS
200 210 220 230 240 250
270 280 290 300 310 320
pF1KE0 IEMVHKALKKQ-EEDPEYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLA
.:. .. ..: ::. : ...:::.:::: :.::::.......: ::.. .: :: ::.
CCDS98 FEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQKRKELLLS
260 270 280 290 300 310
330 340 350 360 370
pF1KE0 SQKPFKFIAREEQ-KRAAREKQLRDFLKYKKKTNRFKA-RPIPRSTYGSTTNDKLKEEEL
: :::.:. .::: :.:::...: . : .. :: : ::.: . .:::.: ::
CCDS98 SLKPFSFLEKEEQLKEAARQRDLAA--TAEAKISKQKATRRIPKSILEPALGDKLQEAEL
320 330 340 350 360 370
380 390 400 410 420
pF1KE0 YRNLRTQLRAQEHLQ-NSSPLPCRSACGCRNPRCPE--QAVKLKCKH-------KVRCPT
.:..: :.:: . :: :::. : . .:: : :: : .: .
CCDS98 FRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRVNPVV
380 390 400 410 420 430
430 440 450 460 470 480
pF1KE0 PDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHASIKREKILADIEADEENLKETRW
::.: : . .:.. .... . : ::: :... .: : ... .
CCDS98 PDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRRQDSPQPPAT
440 450 460 470 480 490
490 500 510 520 530 540
pF1KE0 PYLSPRRKSPVRCAGVNPVPCNCNPPVPTVSSRGREQAVRRSLEEKKMLEEERNRILTKQ
: :: .: .:. . : : : ..: ::.::: .:: :: .: . : .
CCDS98 PL--PRSRS---LSGLASLSANTLPVHITDATRKRESAVRSALE-KKNKADESIQWLEIH
500 510 520 530 540
550 560 570 580 590 600
pF1KE0 KQRMKELQKLLTTRAKAYDSHQSLAQISKSRVKCLRKSEKERMREYQRELEEREEKLKKR
:.. . ..: .: ::::.: :.:: .. :...: :.....: .::..:::: ..... :
CCDS98 KKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQRIQTR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 PLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKVLEYFNNQETKSVTEDKE
: :::.::. :. ::. : .::: :. ..:: .:::. ... :: .. .:
CCDS98 PYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAV-----QEKETKIKDFP
610 620 630 640 650 660
670 680 690 700 710
pF1KE0 SFNEEEKIEER--ENGEENYFIDTNSQDSYKEKDEANEESEEEKSVEESH
:.: :. : :.: :. . . : : .: ...: :
CCDS98 RFQETTKLSIRDPEQGLEGSLEQPASP--RKVLEELSHQSPENLVSLA
670 680 690 700 710
716 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 16:08:58 2016 done: Thu Nov 3 16:08:58 2016
Total Scan time: 4.330 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]