Result of FASTA (omim) for
pFN21AE1864
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1864, 385 aa
1>>>pF1KE1864 385 - 385 aa - 385 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.5747+/-0.000362; mu= 21.5101+/- 0.022
mean_var=75.5254+/-15.075, 0's: 0 Z-trim(114.2): 155 B-trim: 9 in 2/55
Lambda= 0.147580
statistics sampled from 23712 (23881) to 23712 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.663), E-opt: 0.2 (0.28), width: 16
Scan time: 8.480
The best scores are: opt bits E(85289)
NP_000238 (OMIM: 600169) MHC class I polypeptide-r ( 383) 2525 547.1 2.6e-155
NP_001170990 (OMIM: 600169) MHC class I polypeptid ( 332) 2152 467.6 1.9e-131
NP_005922 (OMIM: 602436) MHC class I polypeptide-r ( 383) 2123 461.5 1.5e-129
NP_001276089 (OMIM: 602436) MHC class I polypeptid ( 351) 1953 425.2 1.1e-118
NP_001276082 (OMIM: 600169) MHC class I polypeptid ( 235) 1469 322.0 9e-88
NP_001276081 (OMIM: 600169) MHC class I polypeptid ( 235) 1469 322.0 9e-88
NP_001276090 (OMIM: 602436) MHC class I polypeptid ( 340) 1286 283.2 6.2e-76
NP_001276083 (OMIM: 600169) MHC class I polypeptid ( 194) 1029 228.2 1.3e-59
NP_005505 (OMIM: 106300,142830,608579) major histo ( 362) 518 119.7 1.1e-26
NP_001229971 (OMIM: 142840,177900,609423) HLA clas ( 366) 518 119.7 1.1e-26
NP_002108 (OMIM: 142840,177900,609423) HLA class I ( 366) 515 119.1 1.7e-26
XP_016866297 (OMIM: 143010) PREDICTED: HLA class I ( 399) 515 119.1 1.8e-26
XP_016866296 (OMIM: 143010) PREDICTED: HLA class I ( 399) 515 119.1 1.8e-26
NP_002107 (OMIM: 142800,608579) HLA class I histoc ( 365) 505 117.0 7.4e-26
NP_005507 (OMIM: 143010) HLA class I histocompatib ( 358) 502 116.3 1.1e-25
XP_016866298 (OMIM: 143010) PREDICTED: HLA class I ( 359) 502 116.3 1.1e-25
XP_011512845 (OMIM: 104300,176100,176200,235200,61 ( 348) 499 115.7 1.7e-25
NP_000401 (OMIM: 104300,176100,176200,235200,61263 ( 348) 499 115.7 1.7e-25
XP_016866300 (OMIM: 143110) PREDICTED: HLA class I ( 431) 497 115.3 2.7e-25
NP_001229687 (OMIM: 142800,608579) HLA class I his ( 365) 496 115.0 2.8e-25
NP_001287678 (OMIM: 104300,176100,176200,235200,61 ( 337) 494 114.6 3.6e-25
XP_011512866 (OMIM: 143110) PREDICTED: HLA class I ( 343) 493 114.4 4.2e-25
NP_061823 (OMIM: 143110) HLA class I histocompatib ( 346) 493 114.4 4.2e-25
XP_016866302 (OMIM: 143110) PREDICTED: HLA class I ( 388) 493 114.4 4.5e-25
XP_016866301 (OMIM: 143110) PREDICTED: HLA class I ( 420) 493 114.5 4.8e-25
XP_016866299 (OMIM: 143110) PREDICTED: HLA class I ( 435) 493 114.5 4.9e-25
NP_001091949 (OMIM: 143110) HLA class I histocompa ( 442) 493 114.5 4.9e-25
NP_002118 (OMIM: 142871,600807) HLA class I histoc ( 338) 491 113.9 5.5e-25
XP_016866305 (OMIM: 142871,600807) PREDICTED: HLA ( 343) 491 114.0 5.6e-25
XP_011512859 (OMIM: 106300,142830,608579) PREDICTE ( 323) 488 113.3 8.4e-25
XP_016885777 (OMIM: 142800,608579) PREDICTED: HLA ( 362) 487 113.1 1e-24
XP_005275388 (OMIM: 142800,608579) PREDICTED: HLA ( 391) 487 113.2 1.1e-24
NP_620578 (OMIM: 104300,176100,176200,235200,61263 ( 325) 484 112.4 1.5e-24
NP_001522 (OMIM: 600764) major histocompatibility ( 341) 459 107.1 6.3e-23
NP_620576 (OMIM: 104300,176100,176200,235200,61263 ( 260) 407 95.9 1.1e-19
NP_001176 (OMIM: 194460) zinc-alpha-2-glycoprotein ( 298) 393 93.0 9.7e-19
XP_011507765 (OMIM: 600764) PREDICTED: major histo ( 254) 368 87.6 3.5e-17
XP_016866304 (OMIM: 143110) PREDICTED: HLA class I ( 228) 355 84.8 2.2e-16
XP_016866303 (OMIM: 143110) PREDICTED: HLA class I ( 324) 355 85.0 2.8e-16
NP_004098 (OMIM: 601437) IgG receptor FcRn large s ( 365) 346 83.1 1.1e-15
NP_001129491 (OMIM: 601437) IgG receptor FcRn larg ( 365) 346 83.1 1.1e-15
NP_620573 (OMIM: 104300,176100,176200,235200,61263 ( 256) 294 71.9 1.9e-12
NP_620579 (OMIM: 104300,176100,176200,235200,61263 ( 168) 292 71.3 2e-12
NP_001181928 (OMIM: 600764) major histocompatibili ( 296) 289 70.9 4.5e-12
NP_620577 (OMIM: 104300,176100,176200,235200,61263 ( 246) 268 66.3 8.8e-11
NP_620575 (OMIM: 104300,176100,176200,235200,61263 ( 334) 268 66.5 1.1e-10
NP_620572 (OMIM: 104300,176100,176200,235200,61263 ( 242) 263 65.2 1.8e-10
XP_016866306 (OMIM: 142871,600807) PREDICTED: HLA ( 246) 260 64.6 2.9e-10
XP_016866307 (OMIM: 142871,600807) PREDICTED: HLA ( 246) 260 64.6 2.9e-10
NP_001091948 (OMIM: 143110) HLA class I histocompa ( 254) 251 62.7 1.1e-09
>>NP_000238 (OMIM: 600169) MHC class I polypeptide-relat (383 aa)
initn: 2216 init1: 2135 opt: 2525 Z-score: 2909.3 bits: 547.1 E(85289): 2.6e-155
Smith-Waterman score: 2525; 96.4% identity (98.4% similar) in 385 aa overlap (1-385:1-383)
10 20 30 40 50 60
pF1KE1 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFLRYD
::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: :
NP_000 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IHEDNSTRSSQHFYYDGELFLSQNVETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHY
::::::::::::::::::::::::.::.:::.::::::::::::::::::::::::::::
NP_000 IHEDNSTRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 HAMHADCLQELRRYLESSVVLRRRVPPMVNVTRSEASEGNITVTCRASSFYPRNITLTWR
:::::::::::::::.:.::::: ::::::::::::::::::::::::.::: ::::.::
NP_000 HAMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 LVLQSHWQTFHVSAVAAAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSD
::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
NP_000 LVLQSHWQTFHVSAVAAAA--IFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSD
310 320 330 340 350
370 380
pF1KE1 HRDATQLGFQPLMSALGSTGSTEGA
:::::::::::::: ::::::::::
NP_000 HRDATQLGFQPLMSDLGSTGSTEGA
360 370 380
>>NP_001170990 (OMIM: 600169) MHC class I polypeptide-re (332 aa)
initn: 2152 init1: 2152 opt: 2152 Z-score: 2480.9 bits: 467.6 E(85289): 1.9e-131
Smith-Waterman score: 2152; 98.4% identity (99.4% similar) in 317 aa overlap (1-317:1-317)
10 20 30 40 50 60
pF1KE1 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFLRYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFLRYD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IHEDNSTRSSQHFYYDGELFLSQNVETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHY
::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::
NP_001 IHEDNSTRSSQHFYYDGELFLSQNLETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 HAMHADCLQELRRYLESSVVLRRRVPPMVNVTRSEASEGNITVTCRASSFYPRNITLTWR
:::::::::::::::::.::::: ::::::::::::::::::::::::::::::: ::::
NP_001 HAMHADCLQELRRYLESGVVLRRTVPPMVNVTRSEASEGNITVTCRASSFYPRNIILTWR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKV
:::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
NP_001 QDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICRGEEQRFTCYMEHSGNHSTHPVPSGKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 LVLQSHWQTFHVSAVAAAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSD
:::::::::::::::::
NP_001 LVLQSHWQTFHVSAVAAGCCYFCYYYFLCPLL
310 320 330
>>NP_005922 (OMIM: 602436) MHC class I polypeptide-relat (383 aa)
initn: 2123 init1: 1768 opt: 2123 Z-score: 2446.8 bits: 461.5 E(85289): 1.5e-129
Smith-Waterman score: 2123; 83.6% identity (91.7% similar) in 384 aa overlap (1-384:1-382)
10 20 30 40 50 60
pF1KE1 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFLRYD
:::: :.:.:: ::::::.:::::::::::: ::: ::::::::::: :::::::::::
NP_005 MGLGRVLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCE
::: ::::::::::.::: :::: ::.::: ::.::: ::.:::::: ::::::::::::
NP_005 RQKRRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IHEDNSTRSSQHFYYDGELFLSQNVETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHY
::::.:::.:.:::::::::::::.::.: ::::::::::::::: :: :::::::::::
NP_005 IHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 HAMHADCLQELRRYLESSVVLRRRVPPMVNVTRSEASEGNITVTCRASSFYPRNITLTWR
.::.:::::.:.:::.:.:..:: :::::::: ::.::::::::::::::::::::::::
NP_005 RAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKV
::::::::.::::::::::::::::::::::: :::::::::::::::::.::::::::.
NP_005 QDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 LVLQSHWQTFHVSAVAAAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSD
:::::. : :.:: . .:::. : :::::::::::::::::::::::::::.:
NP_005 LVLQSQRTDFPY--VSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGD
310 320 330 340 350
370 380
pF1KE1 HRDATQLGFQPLMSALGSTGSTEGA
::::.:::::::::: ::::::::
NP_005 HRDAAQLGFQPLMSATGSTGSTEGT
360 370 380
>>NP_001276089 (OMIM: 602436) MHC class I polypeptide-re (351 aa)
initn: 1953 init1: 1598 opt: 1953 Z-score: 2251.6 bits: 425.2 E(85289): 1.1e-118
Smith-Waterman score: 1953; 84.0% identity (92.0% similar) in 351 aa overlap (34-384:2-350)
10 20 30 40 50 60
pF1KE1 GPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFLRYDRQK
::: ::::::::::: ::::::::::::::
NP_001 MVLSQDGSVQSGFLAEGHLDGQPFLRYDRQK
10 20 30
70 80 90 100 110 120
pF1KE1 CRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHE
::::::::::.::: :::: ::.::: ::.::: ::.:::::: :::::::::::::::
NP_001 RRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHE
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 DNSTRSSQHFYYDGELFLSQNVETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAM
:.:::.:.:::::::::::::.::.: ::::::::::::::: :: :::::::::::.::
NP_001 DSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAM
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 HADCLQELRRYLESSVVLRRRVPPMVNVTRSEASEGNITVTCRASSFYPRNITLTWRQDG
.:::::.:.:::.:.:..:: :::::::: ::.:::::::::::::::::::::::::::
NP_001 QADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 VSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKVLVL
:::::.::::::::::::::::::::::: :::::::::::::::::.::::::::.:::
NP_001 VSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKALVL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 QSHWQTFHVSAVAAAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHRD
::. : :.:: . .:::. : :::::::::::::::::::::::::::.::::
NP_001 QSQRTDFPY--VSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGDHRD
280 290 300 310 320
370 380
pF1KE1 ATQLGFQPLMSALGSTGSTEGA
:.:::::::::: ::::::::
NP_001 AAQLGFQPLMSATGSTGSTEGT
330 340 350
>>NP_001276082 (OMIM: 600169) MHC class I polypeptide-re (235 aa)
initn: 1469 init1: 1469 opt: 1469 Z-score: 1696.8 bits: 322.0 E(85289): 9e-88
Smith-Waterman score: 1469; 97.7% identity (99.1% similar) in 220 aa overlap (98-317:1-220)
70 80 90 100 110 120
pF1KE1 PQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHEDNST
::::::::::::::::::::::::::::::
NP_001 MTLAHIKDQKEGLHSLQEIRVCEIHEDNST
10 20 30
130 140 150 160 170 180
pF1KE1 RSSQHFYYDGELFLSQNVETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADC
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
NP_001 RSSQHFYYDGELFLSQNLETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADC
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE1 LQELRRYLESSVVLRRRVPPMVNVTRSEASEGNITVTCRASSFYPRNITLTWRQDGVSLS
::::::::::.::::: ::::::::::::::::::::::::::::::: :::::::::::
NP_001 LQELRRYLESGVVLRRTVPPMVNVTRSEASEGNITVTCRASSFYPRNIILTWRQDGVSLS
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE1 HDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQSHW
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
NP_001 HDTQQWGDVLPDGNGTYQTWVATRICRGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQSHW
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE1 QTFHVSAVAAAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHRDATQL
::::::::::
NP_001 QTFHVSAVAAGCCYFCYYYFLCPLL
220 230
>>NP_001276081 (OMIM: 600169) MHC class I polypeptide-re (235 aa)
initn: 1469 init1: 1469 opt: 1469 Z-score: 1696.8 bits: 322.0 E(85289): 9e-88
Smith-Waterman score: 1469; 97.7% identity (99.1% similar) in 220 aa overlap (98-317:1-220)
70 80 90 100 110 120
pF1KE1 PQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHEDNST
::::::::::::::::::::::::::::::
NP_001 MTLAHIKDQKEGLHSLQEIRVCEIHEDNST
10 20 30
130 140 150 160 170 180
pF1KE1 RSSQHFYYDGELFLSQNVETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADC
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
NP_001 RSSQHFYYDGELFLSQNLETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADC
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE1 LQELRRYLESSVVLRRRVPPMVNVTRSEASEGNITVTCRASSFYPRNITLTWRQDGVSLS
::::::::::.::::: ::::::::::::::::::::::::::::::: :::::::::::
NP_001 LQELRRYLESGVVLRRTVPPMVNVTRSEASEGNITVTCRASSFYPRNIILTWRQDGVSLS
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE1 HDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQSHW
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
NP_001 HDTQQWGDVLPDGNGTYQTWVATRICRGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQSHW
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE1 QTFHVSAVAAAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHRDATQL
::::::::::
NP_001 QTFHVSAVAAGCCYFCYYYFLCPLL
220 230
>>NP_001276090 (OMIM: 602436) MHC class I polypeptide-re (340 aa)
initn: 1863 init1: 931 opt: 1286 Z-score: 1484.3 bits: 283.2 E(85289): 6.2e-76
Smith-Waterman score: 1779; 74.2% identity (81.0% similar) in 384 aa overlap (1-384:1-339)
10 20 30 40 50 60
pF1KE1 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFLRYD
:::: :.:.:: ::::::.:::::::::::: ::: ::::::::::: :::::::::::
NP_001 MGLGRVLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCE
::: ::::::::::.::: :::: ::.::: ::.::: ::.:::::: :
NP_001 RQKRRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQK-G-----------
70 80 90 100
130 140 150 160 170 180
pF1KE1 IHEDNSTRSSQHFYYDGELFLSQNVETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHY
:::::::::::::: :: :::::::::::
NP_001 -------------------------------VPQSSRAQTLAMNVTNFWKEDAMKTKTHY
110 120 130
190 200 210 220 230 240
pF1KE1 HAMHADCLQELRRYLESSVVLRRRVPPMVNVTRSEASEGNITVTCRASSFYPRNITLTWR
.::.:::::.:.:::.:.:..:: :::::::: ::.::::::::::::::::::::::::
NP_001 RAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWR
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE1 QDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKV
::::::::.::::::::::::::::::::::: :::::::::::::::::.::::::::.
NP_001 QDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKA
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE1 LVLQSHWQTFHVSAVAAAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSD
:::::. : :.:: . .:::. : :::::::::::::::::::::::::::.:
NP_001 LVLQSQRTDFPY--VSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGD
260 270 280 290 300 310
370 380
pF1KE1 HRDATQLGFQPLMSALGSTGSTEGA
::::.:::::::::: ::::::::
NP_001 HRDAAQLGFQPLMSATGSTGSTEGT
320 330 340
>>NP_001276083 (OMIM: 600169) MHC class I polypeptide-re (194 aa)
initn: 1029 init1: 1029 opt: 1029 Z-score: 1191.5 bits: 228.2 E(85289): 1.3e-59
Smith-Waterman score: 1029; 90.9% identity (95.8% similar) in 165 aa overlap (153-317:15-179)
130 140 150 160 170 180
pF1KE1 EDNSTRSSQHFYYDGELFLSQNVETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHYHA
::.. .. . . :::::::::::::::::
NP_001 MGQRDQGLDRERKGPQDDPGSYQGPERRNFLKEDAMKTKTHYHA
10 20 30 40
190 200 210 220 230 240
pF1KE1 MHADCLQELRRYLESSVVLRRRVPPMVNVTRSEASEGNITVTCRASSFYPRNITLTWRQD
:::::::::::::::.::::: ::::::::::::::::::::::::::::::: ::::::
NP_001 MHADCLQELRRYLESGVVLRRTVPPMVNVTRSEASEGNITVTCRASSFYPRNIILTWRQD
50 60 70 80 90 100
250 260 270 280 290 300
pF1KE1 GVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKVLV
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
NP_001 GVSLSHDTQQWGDVLPDGNGTYQTWVATRICRGEEQRFTCYMEHSGNHSTHPVPSGKVLV
110 120 130 140 150 160
310 320 330 340 350 360
pF1KE1 LQSHWQTFHVSAVAAAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHR
:::::::::::::::
NP_001 LQSHWQTFHVSAVAAGCCYFCYYYFLCPLL
170 180 190
>>NP_005505 (OMIM: 106300,142830,608579) major histocomp (362 aa)
initn: 295 init1: 137 opt: 518 Z-score: 600.2 bits: 119.7 E(85289): 1.1e-26
Smith-Waterman score: 518; 30.1% identity (63.6% similar) in 349 aa overlap (6-342:9-341)
10 20 30 40 50
pF1KE1 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFL
:.:::.. . .. :.. ::.:: : .: : . :.. ..: :.
NP_005 MLVMAPRTVLLLLSAALALTETWAGS--HSMRYFYTSVSRPGRGEPRFISVGYVDDTQFV
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 RYDRQKC--RAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIK---DQKE-GLH
:.: . : .:.. : :. : . :::.:. .... : .: ... .:.: : :
NP_005 RFDSDAASPREEPRAPWIEQE-GPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 SLQEIRVCEIHEDNST-RSSQHFYYDGELFLSQNVETEEWTVPQSSRAQTLAMNVRNFLK
.:: . :.. :. :. ... :::. ... : . . ::. ... :: .. :..
NP_005 TLQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTA-AQ---ITQRKW--
120 130 140 150 160 170
180 190 200 210 220
pF1KE1 EDAMKTKTHYHAMHADCLQELRRYLESSV-VLRRRVPPMVNVTRSEASEGNITVTCRASS
: : ... . ....:.. ::::::.. :.: :: ..::. :. . :. : : .
NP_005 EAAREAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 FYPRNITLTWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGN
::: .:::::..:: . ..::. .. : :. :.: :.:. . .:::::.::...: :
NP_005 FYPAEITLTWQRDGEDQTQDTELV-ETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEG-
240 250 260 270 280
290 300 310 320 330 340
pF1KE1 HSTHPVPSGKVLVLQ-SHWQTFHVSAVAAAAAAIFVIIIFYVRC---CKKKTSAAEGPEL
.:. .: . : .: . ...:. :.. :..: : :..:.:...:
NP_005 -----LPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSY
290 300 310 320 330 340
350 360 370 380
pF1KE1 VSLQVLDQHPVGTSDHRDATQLGFQPLMSALGSTGSTEGA
NP_005 SQAACSDSAQGSDVSLTA
350 360
>>NP_001229971 (OMIM: 142840,177900,609423) HLA class I (366 aa)
initn: 364 init1: 138 opt: 518 Z-score: 600.2 bits: 119.7 E(85289): 1.1e-26
Smith-Waterman score: 518; 30.0% identity (64.0% similar) in 350 aa overlap (6-342:9-342)
10 20 30 40 50
pF1KE1 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFL
..:::.: . .. : . ::.:: :..: : . :.. ..: :.
NP_001 MRVMAPRALLLLLSGGLALTETWACS--HSMRYFDTAVSRPGRGEPRFISVGYVDDTQFV
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 RYDRQKC--RAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIK---DQKE-GLH
:.: . :..:.. :.:. : . :::::.. ... :..: ... .:.: : :
NP_001 RFDSDAASPRGEPRAPWVEQE-GPEYWDRETQNYKRQAQADRVSLRNLRGYYNQSEDGSH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 SLQEIRVCEIHEDNST-RSSQHFYYDGELFLSQNVETEEWTVPQSSRAQTLAMNVRNFLK
.::.. :.. :. :. .. :::. ... : . . ::. :.: :. .. :
NP_001 TLQRMYGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTA-----ADTAAQITQR--K
120 130 140 150 160 170
180 190 200 210 220
pF1KE1 EDAMKTKTHYHA-MHADCLQELRRYLESSV-VLRRRVPPMVNVTRSEASEGNITVTCRAS
.: .. . .: ... :.. ::::::.. .:.: :: ..::. :. . :. : :
NP_001 LEAARAAEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWAL
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 SFYPRNITLTWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSG
.::: .:::::..:: . ..::. .. : :.::.: :.:. . .:.:::.::.:.: :
NP_001 GFYPAEITLTWQRDGEDQTQDTELV-ETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEG
240 250 260 270 280
290 300 310 320 330 340
pF1KE1 NHSTHPVPSGKVLVLQSHWQTFHVSAVAAAAAAIFVIIIF----YVRCCKKKTSAAEGPE
. .:. . : :. . ...:. :.. :. .. . :..:.:...:
NP_001 LQ--EPLT---LSWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKGGS
290 300 310 320 330 340
350 360 370 380
pF1KE1 LVSLQVLDQHPVGTSDHRDATQLGFQPLMSALGSTGSTEGA
NP_001 CSQAACSNSAQGSDESLITCKA
350 360
385 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 21:27:20 2016 done: Sun Nov 6 21:27:22 2016
Total Scan time: 8.480 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]