Result of FASTA (ccds) for
pFN21AE1864
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1864, 385 aa
1>>>pF1KE1864 385 - 385 aa - 385 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9608+/-0.000833; mu= 19.0134+/- 0.050
mean_var=74.6230+/-15.067, 0's: 0 Z-trim(107.3): 75 B-trim: 5 in 2/49
Lambda= 0.148470
statistics sampled from 9445 (9524) to 9445 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.293), width: 16
Scan time: 2.470
The best scores are: opt bits E(32554)
CCDS56412.1 MICA gene_id:100507436|Hs108|chr6 ( 332) 2152 470.3 1.1e-132
CCDS43449.1 MICB gene_id:4277|Hs108|chr6 ( 383) 2123 464.1 9.3e-131
CCDS75423.1 MICB gene_id:4277|Hs108|chr6 ( 351) 1953 427.7 7.9e-120
CCDS75421.1 MICA gene_id:100507436|Hs108|chr6 ( 235) 1469 323.9 9.5e-89
CCDS75422.1 MICB gene_id:4277|Hs108|chr6 ( 340) 1286 284.8 7.9e-77
CCDS34394.1 B gene_id:3106|Hs108|chr6 ( 362) 518 120.3 2.7e-27
CCDS34393.1 C gene_id:3107|Hs108|chr6 ( 366) 515 119.7 4.3e-27
CCDS34373.1 A gene_id:3105|Hs108|chr6 ( 365) 505 117.5 1.9e-26
CCDS34379.1 E gene_id:3133|Hs108|chr6 ( 358) 502 116.9 2.9e-26
CCDS4578.1 HFE gene_id:3077|Hs108|chr6 ( 348) 499 116.2 4.5e-26
CCDS75412.1 HFE gene_id:3077|Hs108|chr6 ( 337) 494 115.1 9.2e-26
CCDS43438.1 F gene_id:3134|Hs108|chr6 ( 346) 493 114.9 1.1e-25
CCDS43437.1 F gene_id:3134|Hs108|chr6 ( 442) 493 115.0 1.3e-25
CCDS4668.1 G gene_id:3135|Hs108|chr6 ( 338) 491 114.5 1.4e-25
CCDS47387.1 HFE gene_id:3077|Hs108|chr6 ( 325) 484 113.0 3.9e-25
CCDS1342.1 MR1 gene_id:3140|Hs108|chr1 ( 341) 459 107.7 1.7e-23
CCDS4580.1 HFE gene_id:3077|Hs108|chr6 ( 260) 407 96.4 3.1e-20
CCDS5680.1 AZGP1 gene_id:563|Hs108|chr7 ( 298) 393 93.5 2.7e-19
CCDS12770.1 FCGRT gene_id:2217|Hs108|chr19 ( 365) 346 83.5 3.4e-16
CCDS4581.1 HFE gene_id:3077|Hs108|chr6 ( 168) 292 71.6 5.8e-13
CCDS4579.1 HFE gene_id:3077|Hs108|chr6 ( 256) 294 72.2 5.9e-13
CCDS53442.1 MR1 gene_id:3140|Hs108|chr1 ( 296) 289 71.2 1.4e-12
CCDS54975.1 HFE gene_id:3077|Hs108|chr6 ( 246) 268 66.6 2.7e-11
CCDS54974.1 HFE gene_id:3077|Hs108|chr6 ( 334) 268 66.7 3.4e-11
CCDS47386.1 HFE gene_id:3077|Hs108|chr6 ( 242) 263 65.5 5.6e-11
>>CCDS56412.1 MICA gene_id:100507436|Hs108|chr6 (332 aa)
initn: 2152 init1: 2152 opt: 2152 Z-score: 2495.4 bits: 470.3 E(32554): 1.1e-132
Smith-Waterman score: 2152; 98.4% identity (99.4% similar) in 317 aa overlap (1-317:1-317)
10 20 30 40 50 60
pF1KE1 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFLRYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFLRYD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 RQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IHEDNSTRSSQHFYYDGELFLSQNVETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHY
::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::
CCDS56 IHEDNSTRSSQHFYYDGELFLSQNLETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 HAMHADCLQELRRYLESSVVLRRRVPPMVNVTRSEASEGNITVTCRASSFYPRNITLTWR
:::::::::::::::::.::::: ::::::::::::::::::::::::::::::: ::::
CCDS56 HAMHADCLQELRRYLESGVVLRRTVPPMVNVTRSEASEGNITVTCRASSFYPRNIILTWR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKV
:::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
CCDS56 QDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICRGEEQRFTCYMEHSGNHSTHPVPSGKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 LVLQSHWQTFHVSAVAAAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSD
:::::::::::::::::
CCDS56 LVLQSHWQTFHVSAVAAGCCYFCYYYFLCPLL
310 320 330
>>CCDS43449.1 MICB gene_id:4277|Hs108|chr6 (383 aa)
initn: 2123 init1: 1768 opt: 2123 Z-score: 2461.0 bits: 464.1 E(32554): 9.3e-131
Smith-Waterman score: 2123; 83.6% identity (91.7% similar) in 384 aa overlap (1-384:1-382)
10 20 30 40 50 60
pF1KE1 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFLRYD
:::: :.:.:: ::::::.:::::::::::: ::: ::::::::::: :::::::::::
CCDS43 MGLGRVLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCE
::: ::::::::::.::: :::: ::.::: ::.::: ::.:::::: ::::::::::::
CCDS43 RQKRRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IHEDNSTRSSQHFYYDGELFLSQNVETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHY
::::.:::.:.:::::::::::::.::.: ::::::::::::::: :: :::::::::::
CCDS43 IHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 HAMHADCLQELRRYLESSVVLRRRVPPMVNVTRSEASEGNITVTCRASSFYPRNITLTWR
.::.:::::.:.:::.:.:..:: :::::::: ::.::::::::::::::::::::::::
CCDS43 RAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKV
::::::::.::::::::::::::::::::::: :::::::::::::::::.::::::::.
CCDS43 QDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 LVLQSHWQTFHVSAVAAAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSD
:::::. : :.:: . .:::. : :::::::::::::::::::::::::::.:
CCDS43 LVLQSQRTDFPY--VSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGD
310 320 330 340 350
370 380
pF1KE1 HRDATQLGFQPLMSALGSTGSTEGA
::::.:::::::::: ::::::::
CCDS43 HRDAAQLGFQPLMSATGSTGSTEGT
360 370 380
>>CCDS75423.1 MICB gene_id:4277|Hs108|chr6 (351 aa)
initn: 1953 init1: 1598 opt: 1953 Z-score: 2264.7 bits: 427.7 E(32554): 7.9e-120
Smith-Waterman score: 1953; 84.0% identity (92.0% similar) in 351 aa overlap (34-384:2-350)
10 20 30 40 50 60
pF1KE1 GPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFLRYDRQK
::: ::::::::::: ::::::::::::::
CCDS75 MVLSQDGSVQSGFLAEGHLDGQPFLRYDRQK
10 20 30
70 80 90 100 110 120
pF1KE1 CRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHE
::::::::::.::: :::: ::.::: ::.::: ::.:::::: :::::::::::::::
CCDS75 RRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHE
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 DNSTRSSQHFYYDGELFLSQNVETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAM
:.:::.:.:::::::::::::.::.: ::::::::::::::: :: :::::::::::.::
CCDS75 DSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAM
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 HADCLQELRRYLESSVVLRRRVPPMVNVTRSEASEGNITVTCRASSFYPRNITLTWRQDG
.:::::.:.:::.:.:..:: :::::::: ::.:::::::::::::::::::::::::::
CCDS75 QADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 VSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKVLVL
:::::.::::::::::::::::::::::: :::::::::::::::::.::::::::.:::
CCDS75 VSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKALVL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 QSHWQTFHVSAVAAAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHRD
::. : :.:: . .:::. : :::::::::::::::::::::::::::.::::
CCDS75 QSQRTDFPY--VSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGDHRD
280 290 300 310 320
370 380
pF1KE1 ATQLGFQPLMSALGSTGSTEGA
:.:::::::::: ::::::::
CCDS75 AAQLGFQPLMSATGSTGSTEGT
330 340 350
>>CCDS75421.1 MICA gene_id:100507436|Hs108|chr6 (235 aa)
initn: 1469 init1: 1469 opt: 1469 Z-score: 1706.8 bits: 323.9 E(32554): 9.5e-89
Smith-Waterman score: 1469; 97.7% identity (99.1% similar) in 220 aa overlap (98-317:1-220)
70 80 90 100 110 120
pF1KE1 PQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHEDNST
::::::::::::::::::::::::::::::
CCDS75 MTLAHIKDQKEGLHSLQEIRVCEIHEDNST
10 20 30
130 140 150 160 170 180
pF1KE1 RSSQHFYYDGELFLSQNVETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADC
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
CCDS75 RSSQHFYYDGELFLSQNLETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADC
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE1 LQELRRYLESSVVLRRRVPPMVNVTRSEASEGNITVTCRASSFYPRNITLTWRQDGVSLS
::::::::::.::::: ::::::::::::::::::::::::::::::: :::::::::::
CCDS75 LQELRRYLESGVVLRRTVPPMVNVTRSEASEGNITVTCRASSFYPRNIILTWRQDGVSLS
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE1 HDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQSHW
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
CCDS75 HDTQQWGDVLPDGNGTYQTWVATRICRGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQSHW
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE1 QTFHVSAVAAAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHRDATQL
::::::::::
CCDS75 QTFHVSAVAAGCCYFCYYYFLCPLL
220 230
>>CCDS75422.1 MICB gene_id:4277|Hs108|chr6 (340 aa)
initn: 1863 init1: 931 opt: 1286 Z-score: 1492.8 bits: 284.8 E(32554): 7.9e-77
Smith-Waterman score: 1779; 74.2% identity (81.0% similar) in 384 aa overlap (1-384:1-339)
10 20 30 40 50 60
pF1KE1 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFLRYD
:::: :.:.:: ::::::.:::::::::::: ::: ::::::::::: :::::::::::
CCDS75 MGLGRVLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCE
::: ::::::::::.::: :::: ::.::: ::.::: ::.:::::: :
CCDS75 RQKRRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQK-G-----------
70 80 90 100
130 140 150 160 170 180
pF1KE1 IHEDNSTRSSQHFYYDGELFLSQNVETEEWTVPQSSRAQTLAMNVRNFLKEDAMKTKTHY
:::::::::::::: :: :::::::::::
CCDS75 -------------------------------VPQSSRAQTLAMNVTNFWKEDAMKTKTHY
110 120 130
190 200 210 220 230 240
pF1KE1 HAMHADCLQELRRYLESSVVLRRRVPPMVNVTRSEASEGNITVTCRASSFYPRNITLTWR
.::.:::::.:.:::.:.:..:: :::::::: ::.::::::::::::::::::::::::
CCDS75 RAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWR
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE1 QDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKV
::::::::.::::::::::::::::::::::: :::::::::::::::::.::::::::.
CCDS75 QDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKA
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE1 LVLQSHWQTFHVSAVAAAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSD
:::::. : :.:: . .:::. : :::::::::::::::::::::::::::.:
CCDS75 LVLQSQRTDFPY--VSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGD
260 270 280 290 300 310
370 380
pF1KE1 HRDATQLGFQPLMSALGSTGSTEGA
::::.:::::::::: ::::::::
CCDS75 HRDAAQLGFQPLMSATGSTGSTEGT
320 330 340
>>CCDS34394.1 B gene_id:3106|Hs108|chr6 (362 aa)
initn: 295 init1: 137 opt: 518 Z-score: 603.4 bits: 120.3 E(32554): 2.7e-27
Smith-Waterman score: 518; 30.1% identity (63.6% similar) in 349 aa overlap (6-342:9-341)
10 20 30 40 50
pF1KE1 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFL
:.:::.. . .. :.. ::.:: : .: : . :.. ..: :.
CCDS34 MLVMAPRTVLLLLSAALALTETWAGS--HSMRYFYTSVSRPGRGEPRFISVGYVDDTQFV
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 RYDRQKC--RAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIK---DQKE-GLH
:.: . : .:.. : :. : . :::.:. .... : .: ... .:.: : :
CCDS34 RFDSDAASPREEPRAPWIEQE-GPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 SLQEIRVCEIHEDNST-RSSQHFYYDGELFLSQNVETEEWTVPQSSRAQTLAMNVRNFLK
.:: . :.. :. :. ... :::. ... : . . ::. ... :: .. :..
CCDS34 TLQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTA-AQ---ITQRKW--
120 130 140 150 160 170
180 190 200 210 220
pF1KE1 EDAMKTKTHYHAMHADCLQELRRYLESSV-VLRRRVPPMVNVTRSEASEGNITVTCRASS
: : ... . ....:.. ::::::.. :.: :: ..::. :. . :. : : .
CCDS34 EAAREAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 FYPRNITLTWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGN
::: .:::::..:: . ..::. .. : :. :.: :.:. . .:::::.::...: :
CCDS34 FYPAEITLTWQRDGEDQTQDTELV-ETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEG-
240 250 260 270 280
290 300 310 320 330 340
pF1KE1 HSTHPVPSGKVLVLQ-SHWQTFHVSAVAAAAAAIFVIIIFYVRC---CKKKTSAAEGPEL
.:. .: . : .: . ...:. :.. :..: : :..:.:...:
CCDS34 -----LPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSY
290 300 310 320 330 340
350 360 370 380
pF1KE1 VSLQVLDQHPVGTSDHRDATQLGFQPLMSALGSTGSTEGA
CCDS34 SQAACSDSAQGSDVSLTA
350 360
>>CCDS34393.1 C gene_id:3107|Hs108|chr6 (366 aa)
initn: 361 init1: 138 opt: 515 Z-score: 599.8 bits: 119.7 E(32554): 4.3e-27
Smith-Waterman score: 515; 30.0% identity (63.7% similar) in 350 aa overlap (6-342:9-342)
10 20 30 40 50
pF1KE1 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFL
..:::.: . .. : . ::.:: :..: : . :.. ..: :.
CCDS34 MRVMAPRALLLLLSGGLALTETWACS--HSMRYFDTAVSRPGRGEPRFISVGYVDDTQFV
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 RYDRQKC--RAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIK---DQKE-GLH
:.: . :..:.. :.:. : . :::::. ... :..: ... .:.: : :
CCDS34 RFDSDAASPRGEPRAPWVEQE-GPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 SLQEIRVCEIHEDNST-RSSQHFYYDGELFLSQNVETEEWTVPQSSRAQTLAMNVRNFLK
.::.. :.. :. :. .. :::. ... : . . ::. :.: :. .. :
CCDS34 TLQRMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTA-----ADTAAQITQR--K
120 130 140 150 160 170
180 190 200 210 220
pF1KE1 EDAMKTKTHYHA-MHADCLQELRRYLESSV-VLRRRVPPMVNVTRSEASEGNITVTCRAS
.: .. . .: ... :.. ::::::.. .:.: :: ..::. :. . :. : :
CCDS34 LEAARAAEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWAL
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 SFYPRNITLTWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSG
.::: .:::::..:: . ..::. .. : :.::.: :.:. . .:.:::.::.:.: :
CCDS34 GFYPAEITLTWQRDGEDQTQDTELV-ETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEG
240 250 260 270 280
290 300 310 320 330 340
pF1KE1 NHSTHPVPSGKVLVLQSHWQTFHVSAVAAAAAAIFVIIIF----YVRCCKKKTSAAEGPE
. .:. . : :. . ...:. :.. :. .. . :..:.:...:
CCDS34 LQ--EPLT---LSWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKGGS
290 300 310 320 330 340
350 360 370 380
pF1KE1 LVSLQVLDQHPVGTSDHRDATQLGFQPLMSALGSTGSTEGA
CCDS34 CSQAACSNSAQGSDESLITCKA
350 360
>>CCDS34373.1 A gene_id:3105|Hs108|chr6 (365 aa)
initn: 353 init1: 136 opt: 505 Z-score: 588.3 bits: 117.5 E(32554): 1.9e-26
Smith-Waterman score: 505; 31.6% identity (63.6% similar) in 291 aa overlap (6-288:9-289)
10 20 30 40 50
pF1KE1 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFL
..:::.: . .. :.. ::.:: .: .: : . :.: ..: :.
CCDS34 MAVMAPRTLLLLLSGALALTQTWAGS--HSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFV
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 RYDRQKC--RAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIK---DQKE-GLH
:.: . : .:.. : :. : . ::.:::.. .... :. :. .. .:.: : :
CCDS34 RFDSDAASQRMEPRAPWIEQE-GPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 SLQEIRVCEIHEDNS-TRSSQHFYYDGELFLSQNVETEEWTVPQSSRAQTLAMNVRNFLK
..: . :.. :. :. .. :::. ... : . . :: : .: .. .
CCDS34 TIQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWT------AADMAAQITKRKW
120 130 140 150 160 170
180 190 200 210 220
pF1KE1 EDAMKTKTHYHAMHADCLQELRRYLESSV-VLRRRVPPMVNVTRSEASEGNITVTCRASS
: : ... . . :.. ::::::.. .:.: :: ...:. :. . :. : : .
CCDS34 EAAHEAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 FYPRNITLTWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGN
::: .:::::..:: . ..::. .. : :.::.: :.:. . .:::::.::...: :
CCDS34 FYPAEITLTWQRDGEDQTQDTELV-ETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGL
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE1 HSTHPVPSGKVLVLQSHWQTFHVSAVAAAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQ
CCDS34 PKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASS
300 310 320 330 340 350
>>CCDS34379.1 E gene_id:3133|Hs108|chr6 (358 aa)
initn: 388 init1: 142 opt: 502 Z-score: 584.9 bits: 116.9 E(32554): 2.9e-26
Smith-Waterman score: 502; 33.3% identity (63.9% similar) in 294 aa overlap (4-288:4-286)
10 20 30 40 50 60
pF1KE1 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFLRYD
: ..:::. . .. :.. :::.: : .: : . :.. ..: :.:.:
CCDS34 MVDGTLLLLLSEALALTQTWAGS--HSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFD
10 20 30 40 50
70 80 90 100 110
pF1KE1 RQKC--RAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIK---DQKE-GLHSLQ
. : :.. : :. :.. ::::::. ... .:..: .. .:.: : :.::
CCDS34 NDAASPRMVPRAPWMEQE-GSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 EIRVCEIHEDNS-TRSSQHFYYDGELFLSQNVETEEWTVPQSSRAQTLAMNVRNFLKEDA
.. ::. :. :. ..: :::. .:. : . . :: : : .. . ..::
CCDS34 WMHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWT------AVDTAAQISEQKSNDA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 MKTKTHYHAMHAD-CLQELRRYLESSV-VLRRRVPPMVNVTRSEASEGNITVTCRASSFY
... : .:. : :.. :..:::.. .: . :: ..::. :. . :. : : .::
CCDS34 SEAE-HQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFY
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 PRNITLTWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHS
: .:::::.::: . ..::. .. : :.::.: :.:. . .:::::.::...: :
CCDS34 PAEITLTWQQDGEGHTQDTELV-ETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPE
240 250 260 270 280
300 310 320 330 340 350
pF1KE1 THPVPSGKVLVLQSHWQTFHVSAVAAAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVL
CCDS34 PVTLRWKPASQPTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAEWSDS
290 300 310 320 330 340
>>CCDS4578.1 HFE gene_id:3077|Hs108|chr6 (348 aa)
initn: 424 init1: 251 opt: 499 Z-score: 581.6 bits: 116.2 E(32554): 4.5e-26
Smith-Waterman score: 499; 29.6% identity (59.5% similar) in 348 aa overlap (5-342:7-340)
10 20 30 40 50
pF1KE1 MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLAEVHLDGQPFLR
:..::: . . : . :::.: . : . : : : ..: : :.
CCDS45 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 YDRQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGK----DLRMTLAHIKDQKEGLHSLQ
::... :..:. :. . .... : . ...: : . :. . . . .::. :.::
CCDS45 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKES-HTLQ
70 80 90 100 110
120 130 140 150 160 170
pF1KE1 EIRVCEIHEDNSTRSSQHFYYDGELFLSQNVETEEWTVPQSSRAQTLAMNVRNFLKEDAM
: ::..:::::.. .. :::. : .: .: . :. : .. .. .
CCDS45 VILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRA-----AEPRAWPTKLEWERHKI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 KTKTHYHAMHADCLQELRRYLE-SSVVLRRRVPPMVNVTRSEASEGNITVTCRASSFYPR
... . .. :: .:.. :: . :: ..:::.:.::. ... . :. ::: ..::.
CCDS45 RARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTH-HVTSSVTTLRCRALNYYPQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 NITLTWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHST-
:::. : .: .. . ::::.:.:::: :.. . :::::.:: .:: : .
CCDS45 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL
240 250 260 270 280 290
300 310 320 330 340
pF1KE1 ----HPVPSGKVLVLQSHWQTFHVSAVAAAAAAIFVIIIFYVRCCKKKTSAAEGPELVSL
.: ::: .::. .:..:. .. .:. :.: . .. . .: :
CCDS45 IVIWEPSPSG-TLVIGV------ISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAE
300 310 320 330 340
350 360 370 380
pF1KE1 QVLDQHPVGTSDHRDATQLGFQPLMSALGSTGSTEGA
CCDS45 RE
385 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 21:27:20 2016 done: Sun Nov 6 21:27:20 2016
Total Scan time: 2.470 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]