Result of FASTA (omim) for
pFN21AE0269
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0269, 433 aa
1>>>pF1KE0269 433 - 433 aa - 433 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4358+/-0.000345; mu= 14.1098+/- 0.022
mean_var=120.4900+/-24.317, 0's: 0 Z-trim(118.9): 42 B-trim: 1181 in 2/53
Lambda= 0.116842
statistics sampled from 32254 (32296) to 32254 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.734), E-opt: 0.2 (0.379), width: 16
Scan time: 9.420
The best scores are: opt bits E(85289)
NP_085145 (OMIM: 607255) apolipoprotein L5 [Homo s ( 433) 2902 500.0 5e-141
XP_006724384 (OMIM: 607255) PREDICTED: apolipoprot ( 417) 2422 419.0 1.1e-116
XP_016884434 (OMIM: 607255) PREDICTED: apolipoprot ( 361) 2380 411.9 1.3e-114
NP_085144 (OMIM: 607256) apolipoprotein L6 [Homo s ( 343) 626 116.2 1.3e-25
XP_011528694 (OMIM: 607256) PREDICTED: apolipoprot ( 343) 626 116.2 1.3e-25
XP_011528379 (OMIM: 181500,607252) PREDICTED: apol ( 337) 460 88.2 3.4e-17
XP_011528380 (OMIM: 181500,607252) PREDICTED: apol ( 337) 460 88.2 3.4e-17
NP_112092 (OMIM: 181500,607252) apolipoprotein L2 ( 337) 460 88.2 3.4e-17
NP_663612 (OMIM: 181500,607252) apolipoprotein L2 ( 337) 460 88.2 3.4e-17
XP_011528377 (OMIM: 181500,607252) PREDICTED: apol ( 337) 460 88.2 3.4e-17
XP_011528378 (OMIM: 181500,607252) PREDICTED: apol ( 337) 460 88.2 3.4e-17
XP_011528376 (OMIM: 181500,607252) PREDICTED: apol ( 337) 460 88.2 3.4e-17
XP_016884213 (OMIM: 181500,607252) PREDICTED: apol ( 449) 460 88.3 4.2e-17
NP_055164 (OMIM: 607253) apolipoprotein L3 isoform ( 331) 447 86.0 1.5e-16
XP_006724388 (OMIM: 607253) PREDICTED: apolipoprot ( 331) 447 86.0 1.5e-16
NP_663614 (OMIM: 607253) apolipoprotein L3 isoform ( 331) 447 86.0 1.5e-16
XP_006724387 (OMIM: 607253) PREDICTED: apolipoprot ( 331) 447 86.0 1.5e-16
NP_085147 (OMIM: 607253) apolipoprotein L3 isoform ( 331) 447 86.0 1.5e-16
XP_016884438 (OMIM: 607253) PREDICTED: apolipoprot ( 332) 447 86.0 1.5e-16
XP_016884436 (OMIM: 607253) PREDICTED: apolipoprot ( 332) 447 86.0 1.5e-16
XP_016884440 (OMIM: 607253) PREDICTED: apolipoprot ( 332) 447 86.0 1.5e-16
XP_016884435 (OMIM: 607253) PREDICTED: apolipoprot ( 332) 447 86.0 1.5e-16
XP_016884439 (OMIM: 607253) PREDICTED: apolipoprot ( 332) 447 86.0 1.5e-16
XP_016884437 (OMIM: 607253) PREDICTED: apolipoprot ( 332) 447 86.0 1.5e-16
NP_663615 (OMIM: 607253) apolipoprotein L3 isoform ( 402) 447 86.1 1.8e-16
NP_001130013 (OMIM: 603743,612551) apolipoprotein ( 380) 376 74.1 6.8e-13
XP_005261853 (OMIM: 603743,612551) PREDICTED: apol ( 380) 376 74.1 6.8e-13
NP_003652 (OMIM: 603743,612551) apolipoprotein L1 ( 398) 376 74.1 7.1e-13
NP_001130012 (OMIM: 603743,612551) apolipoprotein ( 398) 376 74.1 7.1e-13
NP_663318 (OMIM: 603743,612551) apolipoprotein L1 ( 414) 376 74.2 7.3e-13
XP_011528780 (OMIM: 603743,612551) PREDICTED: apol ( 277) 372 73.3 8.6e-13
NP_085146 (OMIM: 181500,607254) apolipoprotein L4 ( 348) 359 71.2 4.7e-12
NP_663693 (OMIM: 181500,607254) apolipoprotein L4 ( 351) 359 71.2 4.7e-12
NP_663617 (OMIM: 607253) apolipoprotein L3 isoform ( 202) 324 65.1 1.8e-10
NP_663616 (OMIM: 607253) apolipoprotein L3 isoform ( 202) 324 65.1 1.8e-10
XP_016884441 (OMIM: 607253) PREDICTED: apolipoprot ( 202) 324 65.1 1.8e-10
>>NP_085145 (OMIM: 607255) apolipoprotein L5 [Homo sapie (433 aa)
initn: 2902 init1: 2902 opt: 2902 Z-score: 2652.9 bits: 500.0 E(85289): 5e-141
Smith-Waterman score: 2902; 100.0% identity (100.0% similar) in 433 aa overlap (1-433:1-433)
10 20 30 40 50 60
pF1KE0 MPCGKQGNLQVPGSKVLPGLGEGCKEMWLRKVIYGGEVWGKSPEPEFPSLVNLCQSWKIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 MPCGKQGNLQVPGSKVLPGLGEGCKEMWLRKVIYGGEVWGKSPEPEFPSLVNLCQSWKIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 NLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLFLSYFPLHKFELEQNIKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 NLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLFLSYFPLHKFELEQNIKEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 NTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVTAGGSLMLSATGTGLGAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 NTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVTAGGSLMLSATGTGLGAAA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 AITNIVTNVLENRSNSAARDKASRLGPLTTSHEAFGGINWSEIEAAGFCVNKCVKAIQGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 AITNIVTNVLENRSNSAARDKASRLGPLTTSHEAFGGINWSEIEAAGFCVNKCVKAIQGI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQRAFEGTTLAMTNGAWVMGAAGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 KDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQRAFEGTTLAMTNGAWVMGAAGAG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 FLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQELDRLTQHHRHLPQKASQTCSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 FLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQELDRLTQHHRHLPQKASQTCSS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 SRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALRTPKRTVSAPRMLGHQPAPPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 SRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALRTPKRTVSAPRMLGHQPAPPAP
370 380 390 400 410 420
430
pF1KE0 ARKGRQAPGRHRQ
:::::::::::::
NP_085 ARKGRQAPGRHRQ
430
>>XP_006724384 (OMIM: 607255) PREDICTED: apolipoprotein (417 aa)
initn: 2412 init1: 2412 opt: 2422 Z-score: 2215.8 bits: 419.0 E(85289): 1.1e-116
Smith-Waterman score: 2422; 96.6% identity (97.7% similar) in 384 aa overlap (50-433:35-417)
20 30 40 50 60 70
pF1KE0 LGEGCKEMWLRKVIYGGEVWGKSPEPEFPSLVNLCQSWKINNLMSTVHSDEAGMLSYFLF
::.: :.:. .::::::::::::
XP_006 PTKIHPDSQLSRSTVMSFRAEMTQEEMSLILVHL-QAWEKVVKKCGFESDEAGMLSYFLF
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE0 EELMRCDKDSMPDGNLSEEEKLFLSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EELMRCDKDSMPDGNLSEEEKLFLSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSL
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE0 VASSSGAVSGVMNILGLALAPVTAGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VASSSGAVSGVMNILGLALAPVTAGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAAR
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE0 DKASRLGPLTTSHEAFGGINWSEIEAAGFCVNKCVKAIQGIKDLHAYQMAKSNSGFMAMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DKASRLGPLTTSHEAFGGINWSEIEAAGFCVNKCVKAIQGIKDLHAYQMAKSNSGFMAMV
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE0 KNFVAKRHIPFWTARGVQRAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KNFVAKRHIPFWTARGVQRAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLED
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE0 GARTETAEELRALAKKLEQELDRLTQHHRHLPQKASQTCSSSRGRAVRGSRVVKPEGSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GARTETAEELRALAKKLEQELDRLTQHHRHLPQKASQTCSSSRGRAVRGSRVVKPEGSRS
310 320 330 340 350 360
380 390 400 410 420 430
pF1KE0 PLPWPVVEHQPRLGPGVALRTPKRTVSAPRMLGHQPAPPAPARKGRQAPGRHRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLPWPVVEHQPRLGPGVALRTPKRTVSAPRMLGHQPAPPAPARKGRQAPGRHRQ
370 380 390 400 410
>>XP_016884434 (OMIM: 607255) PREDICTED: apolipoprotein (361 aa)
initn: 2380 init1: 2380 opt: 2380 Z-score: 2178.4 bits: 411.9 E(85289): 1.3e-114
Smith-Waterman score: 2380; 100.0% identity (100.0% similar) in 361 aa overlap (73-433:1-361)
50 60 70 80 90 100
pF1KE0 PEPEFPSLVNLCQSWKINNLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLF
::::::::::::::::::::::::::::::
XP_016 MLSYFLFEELMRCDKDSMPDGNLSEEEKLF
10 20 30
110 120 130 140 150 160
pF1KE0 LSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVT
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE0 AGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTTSHEAFGGINWSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTTSHEAFGGINWSE
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE0 IEAAGFCVNKCVKAIQGIKDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQRAFEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEAAGFCVNKCVKAIQGIKDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQRAFEG
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE0 TTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQELDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQELDR
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE0 LTQHHRHLPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALRTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTQHHRHLPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALRTPK
280 290 300 310 320 330
410 420 430
pF1KE0 RTVSAPRMLGHQPAPPAPARKGRQAPGRHRQ
:::::::::::::::::::::::::::::::
XP_016 RTVSAPRMLGHQPAPPAPARKGRQAPGRHRQ
340 350 360
>>NP_085144 (OMIM: 607256) apolipoprotein L6 [Homo sapie (343 aa)
initn: 621 init1: 385 opt: 626 Z-score: 580.8 bits: 116.2 E(85289): 1.3e-25
Smith-Waterman score: 626; 39.5% identity (72.2% similar) in 281 aa overlap (85-363:25-302)
60 70 80 90 100 110
pF1KE0 QSWKINNLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLFLSYFPLHKFELE
:. . ::.:: :::.:: :: : .:.
NP_085 MDNQAERESEAGVGLQRDEDDAPLCEDVELQDGDLSPEEKIFLREFPRLKEDLK
10 20 30 40 50
120 130 140 150 160 170
pF1KE0 QNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVTAGGSLMLSATGT
:: .: .:::..: ::. .::...::.:....::::..:::::::.:.::::.::..:
NP_085 GNIDKLRALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPATGGGSLLLSTAGQ
60 70 80 90 100 110
180 190 200 210 220 230
pF1KE0 GLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTTSHEAFGGINWSE-IEAAGFCVNKC
::..::..:.::...:: .:. :. .: . : ... . .. . ::: . .
NP_085 GLATAAGVTSIVSGTLERSKNKEAQARAEDILPTYDQEDREDEEEKADYVTAAGKIIYNL
120 130 140 150 160 170
240 250 260 270 280 290
pF1KE0 VKAIQ-GIKDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQRAFEGTTLAMTNGAW
.... . :...:. ..: . .: ... .. . ::.:: :::::::..:
NP_085 RNTLKYAKKNVRAFWKLRANPRLANATKRLLTTGQVSSRSRVQVQKAFAGTTLAMTKNAR
180 190 200 210 220 230
300 310 320 330 340 350
pF1KE0 VMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQELDRLTQHHRHLPQ
:.:.. ..: : :.... . ::::..::::. :::::: : .::..: .::: .. : :
NP_085 VLGGVMSAFSLGYDLATLSKEWKHLKEGARTKFAEELRAKALELERKLTELTQLYKSLQQ
240 250 260 270 280 290
360 370 380 390 400 410
pF1KE0 KASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALRTPKRTVSAPRMLG
:. : .::
NP_085 KVR---SRARGVGKDLTGTCETEAYWKELREHVWMWLWLCVCLCVCVYVQFT
300 310 320 330 340
>>XP_011528694 (OMIM: 607256) PREDICTED: apolipoprotein (343 aa)
initn: 621 init1: 385 opt: 626 Z-score: 580.8 bits: 116.2 E(85289): 1.3e-25
Smith-Waterman score: 626; 39.5% identity (72.2% similar) in 281 aa overlap (85-363:25-302)
60 70 80 90 100 110
pF1KE0 QSWKINNLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLFLSYFPLHKFELE
:. . ::.:: :::.:: :: : .:.
XP_011 MDNQAERESEAGVGLQRDEDDAPLCEDVELQDGDLSPEEKIFLREFPRLKEDLK
10 20 30 40 50
120 130 140 150 160 170
pF1KE0 QNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVTAGGSLMLSATGT
:: .: .:::..: ::. .::...::.:....::::..:::::::.:.::::.::..:
XP_011 GNIDKLRALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPATGGGSLLLSTAGQ
60 70 80 90 100 110
180 190 200 210 220 230
pF1KE0 GLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTTSHEAFGGINWSE-IEAAGFCVNKC
::..::..:.::...:: .:. :. .: . : ... . .. . ::: . .
XP_011 GLATAAGVTSIVSGTLERSKNKEAQARAEDILPTYDQEDREDEEEKADYVTAAGKIIYNL
120 130 140 150 160 170
240 250 260 270 280 290
pF1KE0 VKAIQ-GIKDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQRAFEGTTLAMTNGAW
.... . :...:. ..: . .: ... .. . ::.:: :::::::..:
XP_011 RNTLKYAKKNVRAFWKLRANPRLANATKRLLTTGQVSSRSRVQVQKAFAGTTLAMTKNAR
180 190 200 210 220 230
300 310 320 330 340 350
pF1KE0 VMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQELDRLTQHHRHLPQ
:.:.. ..: : :.... . ::::..::::. :::::: : .::..: .::: .. : :
XP_011 VLGGVMSAFSLGYDLATLSKEWKHLKEGARTKFAEELRAKALELERKLTELTQLYKSLQQ
240 250 260 270 280 290
360 370 380 390 400 410
pF1KE0 KASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVALRTPKRTVSAPRMLG
:. : .::
XP_011 KVR---SRARGVGKDLTGTCETEAYWKELREHVWMWLWLCVCLCVCVYVQFT
300 310 320 330 340
>>XP_011528379 (OMIM: 181500,607252) PREDICTED: apolipop (337 aa)
initn: 438 init1: 266 opt: 460 Z-score: 429.7 bits: 88.2 E(85289): 3.4e-17
Smith-Waterman score: 460; 33.9% identity (66.1% similar) in 289 aa overlap (73-356:59-337)
50 60 70 80 90 100
pF1KE0 PEPEFPSLVNLCQSWKINNLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLF
. :...... : :::. .... :
XP_011 LTDDEAWNGFVAAAELPRDEADELRKALNKLASHMVMKDKNRHDKDQ-------QHRQWF
30 40 50 60 70 80
110 120 130 140 150 160
pF1KE0 LSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVT
:. :: : :::..:..: .::..:. .:. : ...:..: :..::....:::.::: :
XP_011 LKEFPRLKRELEDHIRKLRALAEEVEQVHRGTTIANVVSNSVGTTSGILTLLGLGLAPFT
90 100 110 120 130 140
170 180 190 200 210
pF1KE0 AGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTTS----HEAFGGI
: :..: :: :::::::...:. .:.: .. :: .: : :. . : :
XP_011 EGISFVLLDTGMGLGAAAAVAGITCSVVELVNKLRARAQARNLDQSGTNVAKVMKEFVGG
150 160 170 180 190 200
220 230 240 250 260 270
pF1KE0 NWSEIEAAGFCVNKCVKAIQGI-KDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQ
: .. . :.. .. ::: ....: . :..: . :.. . .: .. :.
XP_011 NTPNVLTL---VDNWYQVTQGIGRNIRAIRRARANPQLGAYAPPPHVIGRISAEGGEQVE
210 220 230 240 250
280 290 300 310 320 330
pF1KE0 RAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLE
:. :: . ::. :. ..::: .:.::. :. :. ::: .::..:.::::. :..::
XP_011 RVVEGPAQAMSRGTMIVGAATGGILLLLDVVSLAYESKHLLEGAKSESAEELKKRAQELE
260 270 280 290 300 310
340 350 360 370 380 390
pF1KE0 QELDRLTQHHRHLPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVA
.:. ::. :. : .:
XP_011 GKLNFLTKIHEMLQPGQDQ
320 330
>>XP_011528380 (OMIM: 181500,607252) PREDICTED: apolipop (337 aa)
initn: 438 init1: 266 opt: 460 Z-score: 429.7 bits: 88.2 E(85289): 3.4e-17
Smith-Waterman score: 460; 33.9% identity (66.1% similar) in 289 aa overlap (73-356:59-337)
50 60 70 80 90 100
pF1KE0 PEPEFPSLVNLCQSWKINNLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLF
. :...... : :::. .... :
XP_011 LTDDEAWNGFVAAAELPRDEADELRKALNKLASHMVMKDKNRHDKDQ-------QHRQWF
30 40 50 60 70 80
110 120 130 140 150 160
pF1KE0 LSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVT
:. :: : :::..:..: .::..:. .:. : ...:..: :..::....:::.::: :
XP_011 LKEFPRLKRELEDHIRKLRALAEEVEQVHRGTTIANVVSNSVGTTSGILTLLGLGLAPFT
90 100 110 120 130 140
170 180 190 200 210
pF1KE0 AGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTTS----HEAFGGI
: :..: :: :::::::...:. .:.: .. :: .: : :. . : :
XP_011 EGISFVLLDTGMGLGAAAAVAGITCSVVELVNKLRARAQARNLDQSGTNVAKVMKEFVGG
150 160 170 180 190 200
220 230 240 250 260 270
pF1KE0 NWSEIEAAGFCVNKCVKAIQGI-KDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQ
: .. . :.. .. ::: ....: . :..: . :.. . .: .. :.
XP_011 NTPNVLTL---VDNWYQVTQGIGRNIRAIRRARANPQLGAYAPPPHVIGRISAEGGEQVE
210 220 230 240 250
280 290 300 310 320 330
pF1KE0 RAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLE
:. :: . ::. :. ..::: .:.::. :. :. ::: .::..:.::::. :..::
XP_011 RVVEGPAQAMSRGTMIVGAATGGILLLLDVVSLAYESKHLLEGAKSESAEELKKRAQELE
260 270 280 290 300 310
340 350 360 370 380 390
pF1KE0 QELDRLTQHHRHLPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVA
.:. ::. :. : .:
XP_011 GKLNFLTKIHEMLQPGQDQ
320 330
>>NP_112092 (OMIM: 181500,607252) apolipoprotein L2 [Hom (337 aa)
initn: 438 init1: 266 opt: 460 Z-score: 429.7 bits: 88.2 E(85289): 3.4e-17
Smith-Waterman score: 460; 33.9% identity (66.1% similar) in 289 aa overlap (73-356:59-337)
50 60 70 80 90 100
pF1KE0 PEPEFPSLVNLCQSWKINNLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLF
. :...... : :::. .... :
NP_112 LTDDEAWNGFVAAAELPRDEADELRKALNKLASHMVMKDKNRHDKDQ-------QHRQWF
30 40 50 60 70 80
110 120 130 140 150 160
pF1KE0 LSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVT
:. :: : :::..:..: .::..:. .:. : ...:..: :..::....:::.::: :
NP_112 LKEFPRLKRELEDHIRKLRALAEEVEQVHRGTTIANVVSNSVGTTSGILTLLGLGLAPFT
90 100 110 120 130 140
170 180 190 200 210
pF1KE0 AGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTTS----HEAFGGI
: :..: :: :::::::...:. .:.: .. :: .: : :. . : :
NP_112 EGISFVLLDTGMGLGAAAAVAGITCSVVELVNKLRARAQARNLDQSGTNVAKVMKEFVGG
150 160 170 180 190 200
220 230 240 250 260 270
pF1KE0 NWSEIEAAGFCVNKCVKAIQGI-KDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQ
: .. . :.. .. ::: ....: . :..: . :.. . .: .. :.
NP_112 NTPNVLTL---VDNWYQVTQGIGRNIRAIRRARANPQLGAYAPPPHVIGRISAEGGEQVE
210 220 230 240 250
280 290 300 310 320 330
pF1KE0 RAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLE
:. :: . ::. :. ..::: .:.::. :. :. ::: .::..:.::::. :..::
NP_112 RVVEGPAQAMSRGTMIVGAATGGILLLLDVVSLAYESKHLLEGAKSESAEELKKRAQELE
260 270 280 290 300 310
340 350 360 370 380 390
pF1KE0 QELDRLTQHHRHLPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVA
.:. ::. :. : .:
NP_112 GKLNFLTKIHEMLQPGQDQ
320 330
>>NP_663612 (OMIM: 181500,607252) apolipoprotein L2 [Hom (337 aa)
initn: 438 init1: 266 opt: 460 Z-score: 429.7 bits: 88.2 E(85289): 3.4e-17
Smith-Waterman score: 460; 33.9% identity (66.1% similar) in 289 aa overlap (73-356:59-337)
50 60 70 80 90 100
pF1KE0 PEPEFPSLVNLCQSWKINNLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLF
. :...... : :::. .... :
NP_663 LTDDEAWNGFVAAAELPRDEADELRKALNKLASHMVMKDKNRHDKDQ-------QHRQWF
30 40 50 60 70 80
110 120 130 140 150 160
pF1KE0 LSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVT
:. :: : :::..:..: .::..:. .:. : ...:..: :..::....:::.::: :
NP_663 LKEFPRLKRELEDHIRKLRALAEEVEQVHRGTTIANVVSNSVGTTSGILTLLGLGLAPFT
90 100 110 120 130 140
170 180 190 200 210
pF1KE0 AGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTTS----HEAFGGI
: :..: :: :::::::...:. .:.: .. :: .: : :. . : :
NP_663 EGISFVLLDTGMGLGAAAAVAGITCSVVELVNKLRARAQARNLDQSGTNVAKVMKEFVGG
150 160 170 180 190 200
220 230 240 250 260 270
pF1KE0 NWSEIEAAGFCVNKCVKAIQGI-KDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQ
: .. . :.. .. ::: ....: . :..: . :.. . .: .. :.
NP_663 NTPNVLTL---VDNWYQVTQGIGRNIRAIRRARANPQLGAYAPPPHVIGRISAEGGEQVE
210 220 230 240 250
280 290 300 310 320 330
pF1KE0 RAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLE
:. :: . ::. :. ..::: .:.::. :. :. ::: .::..:.::::. :..::
NP_663 RVVEGPAQAMSRGTMIVGAATGGILLLLDVVSLAYESKHLLEGAKSESAEELKKRAQELE
260 270 280 290 300 310
340 350 360 370 380 390
pF1KE0 QELDRLTQHHRHLPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVA
.:. ::. :. : .:
NP_663 GKLNFLTKIHEMLQPGQDQ
320 330
>>XP_011528377 (OMIM: 181500,607252) PREDICTED: apolipop (337 aa)
initn: 438 init1: 266 opt: 460 Z-score: 429.7 bits: 88.2 E(85289): 3.4e-17
Smith-Waterman score: 460; 33.9% identity (66.1% similar) in 289 aa overlap (73-356:59-337)
50 60 70 80 90 100
pF1KE0 PEPEFPSLVNLCQSWKINNLMSTVHSDEAGMLSYFLFEELMRCDKDSMPDGNLSEEEKLF
. :...... : :::. .... :
XP_011 LTDDEAWNGFVAAAELPRDEADELRKALNKLASHMVMKDKNRHDKDQ-------QHRQWF
30 40 50 60 70 80
110 120 130 140 150 160
pF1KE0 LSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPVT
:. :: : :::..:..: .::..:. .:. : ...:..: :..::....:::.::: :
XP_011 LKEFPRLKRELEDHIRKLRALAEEVEQVHRGTTIANVVSNSVGTTSGILTLLGLGLAPFT
90 100 110 120 130 140
170 180 190 200 210
pF1KE0 AGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTTS----HEAFGGI
: :..: :: :::::::...:. .:.: .. :: .: : :. . : :
XP_011 EGISFVLLDTGMGLGAAAAVAGITCSVVELVNKLRARAQARNLDQSGTNVAKVMKEFVGG
150 160 170 180 190 200
220 230 240 250 260 270
pF1KE0 NWSEIEAAGFCVNKCVKAIQGI-KDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQ
: .. . :.. .. ::: ....: . :..: . :.. . .: .. :.
XP_011 NTPNVLTL---VDNWYQVTQGIGRNIRAIRRARANPQLGAYAPPPHVIGRISAEGGEQVE
210 220 230 240 250
280 290 300 310 320 330
pF1KE0 RAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLE
:. :: . ::. :. ..::: .:.::. :. :. ::: .::..:.::::. :..::
XP_011 RVVEGPAQAMSRGTMIVGAATGGILLLLDVVSLAYESKHLLEGAKSESAEELKKRAQELE
260 270 280 290 300 310
340 350 360 370 380 390
pF1KE0 QELDRLTQHHRHLPQKASQTCSSSRGRAVRGSRVVKPEGSRSPLPWPVVEHQPRLGPGVA
.:. ::. :. : .:
XP_011 GKLNFLTKIHEMLQPGQDQ
320 330
433 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 18:12:36 2016 done: Thu Nov 3 18:12:37 2016
Total Scan time: 9.420 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]