Result of FASTA (omim) for
pFN21AE0244
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0244, 134 aa
1>>>pF1KE0244 134 - 134 aa - 134 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0631+/-0.00024; mu= 7.9414+/- 0.015
mean_var=75.6595+/-14.989, 0's: 0 Z-trim(122.6): 26 B-trim: 36 in 1/57
Lambda= 0.147449
statistics sampled from 40847 (40873) to 40847 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.835), E-opt: 0.2 (0.479), width: 16
Scan time: 4.800
The best scores are: opt bits E(85289)
NP_001308936 (OMIM: 276300,600259,614337) mismatch ( 756) 474 109.1 1.2e-23
NP_001308937 (OMIM: 276300,600259,614337) mismatch ( 756) 474 109.1 1.2e-23
NP_001308935 (OMIM: 276300,600259,614337) mismatch ( 810) 392 91.7 2.3e-18
NP_000526 (OMIM: 276300,600259,614337) mismatch re ( 862) 392 91.7 2.5e-18
NP_001308943 (OMIM: 276300,600259,614337) mismatch ( 873) 392 91.7 2.5e-18
NP_001308944 (OMIM: 276300,600259,614337) mismatch ( 759) 387 90.6 4.6e-18
NP_001308942 (OMIM: 276300,600259,614337) mismatch ( 671) 291 70.2 5.8e-12
NP_001308939 (OMIM: 276300,600259,614337) mismatch ( 675) 284 68.7 1.6e-11
NP_001308934 (OMIM: 276300,600259,614337) mismatch ( 727) 284 68.7 1.7e-11
NP_001308932 (OMIM: 276300,600259,614337) mismatch ( 727) 284 68.7 1.7e-11
NP_001308933 (OMIM: 276300,600259,614337) mismatch ( 727) 284 68.7 1.7e-11
NP_001308938 (OMIM: 276300,600259,614337) mismatch ( 738) 284 68.7 1.8e-11
>>NP_001308936 (OMIM: 276300,600259,614337) mismatch rep (756 aa)
initn: 471 init1: 471 opt: 474 Z-score: 545.3 bits: 109.1 E(85289): 1.2e-23
Smith-Waterman score: 474; 62.4% identity (76.0% similar) in 125 aa overlap (1-123:1-125)
10 20 30 40 50 60
pF1KE0 MWGRRRKLRRLNDVTISTCHVSAKVGTRLVFDHDGKIIQKTPYPHPRGTTVSVKQLFSTL
::::::::::::::::::::.::::::::.:::.::::::::::.::::::::.::::::
NP_001 MWGRRRKLRRLNDVTISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFSTL
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 PVRHKEFQRNIKKKRACFPFAFCRDCQFLEGSPAMLPVQ--PAKLTPRSTPPHPCSLEDN
:::::::::::::. : . .. : . : . : .: : :...:
NP_001 PVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKEN
70 80 90 100 110 120
120 130
pF1KE0 VITVFSSVKNGPGSSR
. .::
NP_001 IGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSSTD
130 140 150 160 170 180
>>NP_001308937 (OMIM: 276300,600259,614337) mismatch rep (756 aa)
initn: 471 init1: 471 opt: 474 Z-score: 545.3 bits: 109.1 E(85289): 1.2e-23
Smith-Waterman score: 474; 62.4% identity (76.0% similar) in 125 aa overlap (1-123:1-125)
10 20 30 40 50 60
pF1KE0 MWGRRRKLRRLNDVTISTCHVSAKVGTRLVFDHDGKIIQKTPYPHPRGTTVSVKQLFSTL
::::::::::::::::::::.::::::::.:::.::::::::::.::::::::.::::::
NP_001 MWGRRRKLRRLNDVTISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFSTL
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 PVRHKEFQRNIKKKRACFPFAFCRDCQFLEGSPAMLPVQ--PAKLTPRSTPPHPCSLEDN
:::::::::::::. : . .. : . : . : .: : :...:
NP_001 PVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKEN
70 80 90 100 110 120
120 130
pF1KE0 VITVFSSVKNGPGSSR
. .::
NP_001 IGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSSTD
130 140 150 160 170 180
>>NP_001308935 (OMIM: 276300,600259,614337) mismatch rep (810 aa)
initn: 383 init1: 383 opt: 392 Z-score: 450.6 bits: 91.7 E(85289): 2.3e-18
Smith-Waterman score: 392; 58.3% identity (73.9% similar) in 115 aa overlap (11-123:117-231)
10 20 30 40
pF1KE0 MWGRRRKLRRLNDVTISTCHVSAKVGTRLVFDHDGKIIQK
:.::::::::.::::::::.:::.::::::
NP_001 HHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHASAKVGTRLMFDHNGKIIQK
90 100 110 120 130 140
50 60 70 80 90
pF1KE0 TPYPHPRGTTVSVKQLFSTLPVRHKEFQRNIKKKRACFPFAFCRDCQFLEGSPAMLPVQ-
::::.::::::::.:::::::::::::::::::. : . .. : . : . :
NP_001 TPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQL
150 160 170 180 190 200
100 110 120 130
pF1KE0 -PAKLTPRSTPPHPCSLEDNVITVFSSVKNGPGSSR
.: : :...:. .::
NP_001 GQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNL
210 220 230 240 250 260
>>NP_000526 (OMIM: 276300,600259,614337) mismatch repair (862 aa)
initn: 383 init1: 383 opt: 392 Z-score: 450.2 bits: 91.7 E(85289): 2.5e-18
Smith-Waterman score: 392; 58.3% identity (73.9% similar) in 115 aa overlap (11-123:117-231)
10 20 30 40
pF1KE0 MWGRRRKLRRLNDVTISTCHVSAKVGTRLVFDHDGKIIQK
:.::::::::.::::::::.:::.::::::
NP_000 HHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHASAKVGTRLMFDHNGKIIQK
90 100 110 120 130 140
50 60 70 80 90
pF1KE0 TPYPHPRGTTVSVKQLFSTLPVRHKEFQRNIKKKRACFPFAFCRDCQFLEGSPAMLPVQ-
::::.::::::::.:::::::::::::::::::. : . .. : . : . :
NP_000 TPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQL
150 160 170 180 190 200
100 110 120 130
pF1KE0 -PAKLTPRSTPPHPCSLEDNVITVFSSVKNGPGSSR
.: : :...:. .::
NP_000 GQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNL
210 220 230 240 250 260
>>NP_001308943 (OMIM: 276300,600259,614337) mismatch rep (873 aa)
initn: 383 init1: 383 opt: 392 Z-score: 450.1 bits: 91.7 E(85289): 2.5e-18
Smith-Waterman score: 392; 58.3% identity (73.9% similar) in 115 aa overlap (11-123:117-231)
10 20 30 40
pF1KE0 MWGRRRKLRRLNDVTISTCHVSAKVGTRLVFDHDGKIIQK
:.::::::::.::::::::.:::.::::::
NP_001 HHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHASAKVGTRLMFDHNGKIIQK
90 100 110 120 130 140
50 60 70 80 90
pF1KE0 TPYPHPRGTTVSVKQLFSTLPVRHKEFQRNIKKKRACFPFAFCRDCQFLEGSPAMLPVQ-
::::.::::::::.:::::::::::::::::::. : . .. : . : . :
NP_001 TPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQL
150 160 170 180 190 200
100 110 120 130
pF1KE0 -PAKLTPRSTPPHPCSLEDNVITVFSSVKNGPGSSR
.: : :...:. .::
NP_001 GQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNL
210 220 230 240 250 260
>>NP_001308944 (OMIM: 276300,600259,614337) mismatch rep (759 aa)
initn: 383 init1: 383 opt: 387 Z-score: 445.3 bits: 90.6 E(85289): 4.6e-18
Smith-Waterman score: 387; 57.9% identity (73.7% similar) in 114 aa overlap (12-123:15-128)
10 20 30 40 50
pF1KE0 MWGRRRKLRRLNDVTISTCHVSAKVGTRLVFDHDGKIIQKTPYPHPRGTTVSVKQLF
.::::::::.::::::::.:::.::::::::::.::::::::.:::
NP_001 MGLSLNTPCLVFSHSDVTISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 STLPVRHKEFQRNIKKKRACFPFAFCRDCQFLEGSPAMLPVQ--PAKLTPRSTPPHPCSL
::::::::::::::::. : . .. : . : . : .: : :.
NP_001 STLPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSI
70 80 90 100 110 120
120 130
pF1KE0 EDNVITVFSSVKNGPGSSR
..:. .::
NP_001 KENIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRS
130 140 150 160 170 180
>>NP_001308942 (OMIM: 276300,600259,614337) mismatch rep (671 aa)
initn: 291 init1: 291 opt: 291 Z-score: 335.8 bits: 70.2 E(85289): 5.8e-12
Smith-Waterman score: 291; 82.4% identity (96.1% similar) in 51 aa overlap (30-80:1-51)
10 20 30 40 50 60
pF1KE0 MWGRRRKLRRLNDVTISTCHVSAKVGTRLVFDHDGKIIQKTPYPHPRGTTVSVKQLFSTL
.:::.::::::::::.::::::::.::::::
NP_001 MFDHNGKIIQKTPYPRPRGTTVSVQQLFSTL
10 20 30
70 80 90 100 110 120
pF1KE0 PVRHKEFQRNIKKKRACFPFAFCRDCQFLEGSPAMLPVQPAKLTPRSTPPHPCSLEDNVI
::::::::::::: .. .::
NP_001 PVRHKEFQRNIKKLQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGR
40 50 60 70 80 90
>>NP_001308939 (OMIM: 276300,600259,614337) mismatch rep (675 aa)
initn: 280 init1: 280 opt: 284 Z-score: 327.7 bits: 68.7 E(85289): 1.6e-11
Smith-Waterman score: 284; 52.1% identity (68.8% similar) in 96 aa overlap (30-123:1-96)
10 20 30 40 50 60
pF1KE0 MWGRRRKLRRLNDVTISTCHVSAKVGTRLVFDHDGKIIQKTPYPHPRGTTVSVKQLFSTL
.:::.::::::::::.::::::::.::::::
NP_001 MFDHNGKIIQKTPYPRPRGTTVSVQQLFSTL
10 20 30
70 80 90 100 110
pF1KE0 PVRHKEFQRNIKKKRACFPFAFCRDCQFLEGSPAMLPVQ--PAKLTPRSTPPHPCSLEDN
:::::::::::::. : . .. : . : . : .: : :...:
NP_001 PVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKEN
40 50 60 70 80 90
120 130
pF1KE0 VITVFSSVKNGPGSSR
. .::
NP_001 IGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSSTD
100 110 120 130 140 150
>>NP_001308934 (OMIM: 276300,600259,614337) mismatch rep (727 aa)
initn: 280 init1: 280 opt: 284 Z-score: 327.2 bits: 68.7 E(85289): 1.7e-11
Smith-Waterman score: 284; 52.1% identity (68.8% similar) in 96 aa overlap (30-123:1-96)
10 20 30 40 50 60
pF1KE0 MWGRRRKLRRLNDVTISTCHVSAKVGTRLVFDHDGKIIQKTPYPHPRGTTVSVKQLFSTL
.:::.::::::::::.::::::::.::::::
NP_001 MFDHNGKIIQKTPYPRPRGTTVSVQQLFSTL
10 20 30
70 80 90 100 110
pF1KE0 PVRHKEFQRNIKKKRACFPFAFCRDCQFLEGSPAMLPVQ--PAKLTPRSTPPHPCSLEDN
:::::::::::::. : . .. : . : . : .: : :...:
NP_001 PVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKEN
40 50 60 70 80 90
120 130
pF1KE0 VITVFSSVKNGPGSSR
. .::
NP_001 IGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSSTD
100 110 120 130 140 150
>>NP_001308932 (OMIM: 276300,600259,614337) mismatch rep (727 aa)
initn: 280 init1: 280 opt: 284 Z-score: 327.2 bits: 68.7 E(85289): 1.7e-11
Smith-Waterman score: 284; 52.1% identity (68.8% similar) in 96 aa overlap (30-123:1-96)
10 20 30 40 50 60
pF1KE0 MWGRRRKLRRLNDVTISTCHVSAKVGTRLVFDHDGKIIQKTPYPHPRGTTVSVKQLFSTL
.:::.::::::::::.::::::::.::::::
NP_001 MFDHNGKIIQKTPYPRPRGTTVSVQQLFSTL
10 20 30
70 80 90 100 110
pF1KE0 PVRHKEFQRNIKKKRACFPFAFCRDCQFLEGSPAMLPVQ--PAKLTPRSTPPHPCSLEDN
:::::::::::::. : . .. : . : . : .: : :...:
NP_001 PVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKEN
40 50 60 70 80 90
120 130
pF1KE0 VITVFSSVKNGPGSSR
. .::
NP_001 IGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSSTD
100 110 120 130 140 150
134 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 19:32:37 2016 done: Thu Nov 3 19:32:37 2016
Total Scan time: 4.800 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]