Result of FASTA (omim) for
pFN21AE1721
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1721, 210 aa
1>>>pF1KE1721 210 - 210 aa - 210 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.3307+/-0.000324; mu= -4.7450+/- 0.020
mean_var=173.5714+/-34.152, 0's: 0 Z-trim(121.0): 13 B-trim: 0 in 0/56
Lambda= 0.097350
statistics sampled from 37077 (37090) to 37077 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.773), E-opt: 0.2 (0.435), width: 16
Scan time: 6.710
The best scores are: opt bits E(85289)
NP_001019979 (OMIM: 601406) B-cell CLL/lymphoma 7 ( 210) 1375 204.2 1.2e-52
NP_066273 (OMIM: 601406) B-cell CLL/lymphoma 7 pro ( 231) 1233 184.3 1.4e-46
NP_001698 (OMIM: 605846) B-cell CLL/lymphoma 7 pro ( 202) 497 80.9 1.6e-15
NP_004756 (OMIM: 605847) B-cell CLL/lymphoma 7 pro ( 217) 418 69.8 3.7e-12
XP_016879374 (OMIM: 605847) PREDICTED: B-cell CLL/ ( 178) 415 69.4 4.1e-12
XP_016879375 (OMIM: 605847) PREDICTED: B-cell CLL/ ( 178) 415 69.4 4.1e-12
XP_016879377 (OMIM: 605847) PREDICTED: B-cell CLL/ ( 178) 415 69.4 4.1e-12
XP_016879376 (OMIM: 605847) PREDICTED: B-cell CLL/ ( 178) 415 69.4 4.1e-12
NP_001273455 (OMIM: 605847) B-cell CLL/lymphoma 7 ( 242) 413 69.1 6.6e-12
XP_011544282 (OMIM: 605847) PREDICTED: B-cell CLL/ ( 293) 413 69.2 7.9e-12
NP_001184173 (OMIM: 605846) B-cell CLL/lymphoma 7 ( 145) 386 65.3 5.8e-11
NP_001287990 (OMIM: 605846) B-cell CLL/lymphoma 7 ( 213) 305 54.0 2.2e-07
>>NP_001019979 (OMIM: 601406) B-cell CLL/lymphoma 7 prot (210 aa)
initn: 1375 init1: 1375 opt: 1375 Z-score: 1065.9 bits: 204.2 E(85289): 1.2e-52
Smith-Waterman score: 1375; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:1-210)
10 20 30 40 50 60
pF1KE1 MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KNKKKGKDEKCGSEVTTPENSSSPGMMDMHDDNSNQSSIADASPIKQENSSNSSPAPEPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNKKKGKDEKCGSEVTTPENSSSPGMMDMHDDNSNQSSIADASPIKQENSSNSSPAPEPN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SAVPSDGTEAKVDEAQADGKEHPGAEDASDEQNSQSSMEHSMNSSEKVDRQPSGDSGLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAVPSDGTEAKVDEAQADGKEHPGAEDASDEQNSQSSMEHSMNSSEKVDRQPSGDSGLAA
130 140 150 160 170 180
190 200 210
pF1KE1 ETSAISQDLEGVPPSKKMKLEASQQNSEEM
::::::::::::::::::::::::::::::
NP_001 ETSAISQDLEGVPPSKKMKLEASQQNSEEM
190 200 210
>>NP_066273 (OMIM: 601406) B-cell CLL/lymphoma 7 protein (231 aa)
initn: 1227 init1: 1227 opt: 1233 Z-score: 957.4 bits: 184.3 E(85289): 1.4e-46
Smith-Waterman score: 1323; 90.9% identity (90.9% similar) in 231 aa overlap (1-210:1-231)
10 20 30 40 50 60
pF1KE1 MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KNKKKGKDEKCGSEVTTPENSSSPGMMDMHDDNSNQSSIADASPIKQENSSNSSPAPEPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 KNKKKGKDEKCGSEVTTPENSSSPGMMDMHDDNSNQSSIADASPIKQENSSNSSPAPEPN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SAVPSDGTEAKVDEAQADGKEHPGAEDASDEQNSQSSMEHSMNSSEKVDRQPSGDSGLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SAVPSDGTEAKVDEAQADGKEHPGAEDASDEQNSQSSMEHSMNSSEKVDRQPSGDSGLAA
130 140 150 160 170 180
190 200 210
pF1KE1 ETSAISQ---------------------DLEGVPPSKKMKLEASQQNSEEM
::::::: :::::::::::::::::::::::
NP_066 ETSAISQVPRSRSQRGSQIGREPIGLSGDLEGVPPSKKMKLEASQQNSEEM
190 200 210 220 230
>>NP_001698 (OMIM: 605846) B-cell CLL/lymphoma 7 protein (202 aa)
initn: 483 init1: 375 opt: 497 Z-score: 399.7 bits: 80.9 E(85289): 1.6e-15
Smith-Waterman score: 508; 45.3% identity (70.6% similar) in 201 aa overlap (1-197:1-187)
10 20 30 40 50 60
pF1KE1 MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKN
:::::::::::::::::::.:::::::::::::::::::::::::.::::::. : .:.
NP_001 MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KNKKKGKDEKCGSEVTTPENSSSPGMMDMHDDNSNQSSIADASPIKQENSSNSSPAPEPN
:..... : : . ::: .....:.::::::..:. .: ..:.::::.:. .
NP_001 KSNSSAAREPNGFPSDASANSSL--LLEFQDENSNQSSVSDVYQLKVDSSTNSSPSPQQS
70 80 90 100 110
130 140 150 160 170
pF1KE1 SAV-PSDGTEAKVDEAQADGKEHPGAEDASDEQNSQSSMEHSMNSSEKVDRQPS--GDSG
.. :. .. ..:..: : . : : :. ::: .:. :. .
NP_001 ESLSPAHTSDFRTDDSQP-----PTLGQEILE-------EPSLPSSEVADEPPTLTKEEP
120 130 140 150 160
180 190 200 210
pF1KE1 LAAETSAISQDLE-GVPPSKKMKLEASQQNSEEM
. ::... .. . :.:: :.
NP_001 VPLETQVVEEEEDSGAPPLKRFCVDQPTVPQTASES
170 180 190 200
>>NP_004756 (OMIM: 605847) B-cell CLL/lymphoma 7 protein (217 aa)
initn: 408 init1: 339 opt: 418 Z-score: 339.3 bits: 69.8 E(85289): 3.7e-12
Smith-Waterman score: 429; 37.6% identity (69.0% similar) in 213 aa overlap (1-198:1-210)
10 20 30 40 50 60
pF1KE1 MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKN
:.::.::::::::::::::.:::.:::::.:::.:::::::::::.:::::..:. ...
NP_004 MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERR
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 K-----NKKKGKDEKCGSEVTTPENSSSPGMMDMHDDNSNQSSIADASPIKQENSSNSSP
. ....:.... .. ..:.... ..:..:.::::: ...: ... . . .
NP_004 RAGGGAERSRGRERR--GRGASPRGGGPLILLDLNDENSNQSFHSEGS-LQKGTEPSPGG
70 80 90 100 110
120 130 140 150 160
pF1KE1 APEPNSAV-PSDGTEAKVDEAQAD--GKEH-PGAEDA--SDEQNSQSSMEH--SMNSSEK
.:.:. : :. :. .::: :.:. ::. : .:: .. : . .:
NP_004 TPQPSRPVSPAGPPEGVPEEAQPPRLGQERDPGGITAGSTDEPPMLTKEEPVPELLEAEA
120 130 140 150 160 170
170 180 190 200 210
pF1KE1 VDRQPSGDSGLAAETSAI--SQDLEGVPPSKKMKLEASQQNSEEM
. : . . .: ..: ::.:: :..
NP_004 PEAYPVFEPVPPVPEAAQGDTEDSEGAPPLKRICPNAPDP
180 190 200 210
>>XP_016879374 (OMIM: 605847) PREDICTED: B-cell CLL/lymp (178 aa)
initn: 359 init1: 339 opt: 415 Z-score: 338.4 bits: 69.4 E(85289): 4.1e-12
Smith-Waterman score: 415; 38.0% identity (70.3% similar) in 192 aa overlap (1-186:1-178)
10 20 30 40 50 60
pF1KE1 MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKN
:.::.::::::::::::::.:::.:::::.:::.:::::::::::.:::::..:. ...
XP_016 MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERR
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 K-----NKKKGKDEKCGSEVTTPENSSSPGMMDMHDDNSNQSSIADASPIKQENSSNSSP
. ....:.... .. ..:.... ..:..:.::::: ...: ... . . .
XP_016 RAGGGAERSRGRERR--GRGASPRGGGPLILLDLNDENSNQSFHSEGS-LQKGTEPSPGG
70 80 90 100 110
120 130 140 150 160 170
pF1KE1 APEPNSAV-PSDGTEAKVDEAQADGKEHPGAEDASDEQNSQSSMEHSMNSSEKVDRQPSG
.:.:. : :. :. .::: . : : . .. ... .: : :..
XP_016 TPQPSRPVSPAGPPEGVPEEAQ---PPRLGQERGRTRSRGHNCWQHR--------RTPNA
120 130 140 150 160
180 190 200 210
pF1KE1 DSGLAAETSAISQDLEGVPPSKKMKLEASQQNSEEM
:.: : .: :
XP_016 DQGGACSRTAGS
170
>>XP_016879375 (OMIM: 605847) PREDICTED: B-cell CLL/lymp (178 aa)
initn: 359 init1: 339 opt: 415 Z-score: 338.4 bits: 69.4 E(85289): 4.1e-12
Smith-Waterman score: 415; 38.0% identity (70.3% similar) in 192 aa overlap (1-186:1-178)
10 20 30 40 50 60
pF1KE1 MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKN
:.::.::::::::::::::.:::.:::::.:::.:::::::::::.:::::..:. ...
XP_016 MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERR
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 K-----NKKKGKDEKCGSEVTTPENSSSPGMMDMHDDNSNQSSIADASPIKQENSSNSSP
. ....:.... .. ..:.... ..:..:.::::: ...: ... . . .
XP_016 RAGGGAERSRGRERR--GRGASPRGGGPLILLDLNDENSNQSFHSEGS-LQKGTEPSPGG
70 80 90 100 110
120 130 140 150 160 170
pF1KE1 APEPNSAV-PSDGTEAKVDEAQADGKEHPGAEDASDEQNSQSSMEHSMNSSEKVDRQPSG
.:.:. : :. :. .::: . : : . .. ... .: : :..
XP_016 TPQPSRPVSPAGPPEGVPEEAQ---PPRLGQERGRTRSRGHNCWQHR--------RTPNA
120 130 140 150 160
180 190 200 210
pF1KE1 DSGLAAETSAISQDLEGVPPSKKMKLEASQQNSEEM
:.: : .: :
XP_016 DQGGACSRTAGS
170
>>XP_016879377 (OMIM: 605847) PREDICTED: B-cell CLL/lymp (178 aa)
initn: 359 init1: 339 opt: 415 Z-score: 338.4 bits: 69.4 E(85289): 4.1e-12
Smith-Waterman score: 415; 38.0% identity (70.3% similar) in 192 aa overlap (1-186:1-178)
10 20 30 40 50 60
pF1KE1 MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKN
:.::.::::::::::::::.:::.:::::.:::.:::::::::::.:::::..:. ...
XP_016 MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERR
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 K-----NKKKGKDEKCGSEVTTPENSSSPGMMDMHDDNSNQSSIADASPIKQENSSNSSP
. ....:.... .. ..:.... ..:..:.::::: ...: ... . . .
XP_016 RAGGGAERSRGRERR--GRGASPRGGGPLILLDLNDENSNQSFHSEGS-LQKGTEPSPGG
70 80 90 100 110
120 130 140 150 160 170
pF1KE1 APEPNSAV-PSDGTEAKVDEAQADGKEHPGAEDASDEQNSQSSMEHSMNSSEKVDRQPSG
.:.:. : :. :. .::: . : : . .. ... .: : :..
XP_016 TPQPSRPVSPAGPPEGVPEEAQ---PPRLGQERGRTRSRGHNCWQHR--------RTPNA
120 130 140 150 160
180 190 200 210
pF1KE1 DSGLAAETSAISQDLEGVPPSKKMKLEASQQNSEEM
:.: : .: :
XP_016 DQGGACSRTAGS
170
>>XP_016879376 (OMIM: 605847) PREDICTED: B-cell CLL/lymp (178 aa)
initn: 359 init1: 339 opt: 415 Z-score: 338.4 bits: 69.4 E(85289): 4.1e-12
Smith-Waterman score: 415; 38.0% identity (70.3% similar) in 192 aa overlap (1-186:1-178)
10 20 30 40 50 60
pF1KE1 MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKN
:.::.::::::::::::::.:::.:::::.:::.:::::::::::.:::::..:. ...
XP_016 MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERR
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 K-----NKKKGKDEKCGSEVTTPENSSSPGMMDMHDDNSNQSSIADASPIKQENSSNSSP
. ....:.... .. ..:.... ..:..:.::::: ...: ... . . .
XP_016 RAGGGAERSRGRERR--GRGASPRGGGPLILLDLNDENSNQSFHSEGS-LQKGTEPSPGG
70 80 90 100 110
120 130 140 150 160 170
pF1KE1 APEPNSAV-PSDGTEAKVDEAQADGKEHPGAEDASDEQNSQSSMEHSMNSSEKVDRQPSG
.:.:. : :. :. .::: . : : . .. ... .: : :..
XP_016 TPQPSRPVSPAGPPEGVPEEAQ---PPRLGQERGRTRSRGHNCWQHR--------RTPNA
120 130 140 150 160
180 190 200 210
pF1KE1 DSGLAAETSAISQDLEGVPPSKKMKLEASQQNSEEM
:.: : .: :
XP_016 DQGGACSRTAGS
170
>>NP_001273455 (OMIM: 605847) B-cell CLL/lymphoma 7 prot (242 aa)
initn: 376 init1: 339 opt: 413 Z-score: 334.7 bits: 69.1 E(85289): 6.6e-12
Smith-Waterman score: 418; 38.4% identity (71.7% similar) in 198 aa overlap (1-181:1-195)
10 20 30 40 50 60
pF1KE1 MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKN
:.::.::::::::::::::.:::.:::::.:::.:::::::::::.:::::..:. ...
NP_001 MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERR
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 K-----NKKKGKDEKCGSEVTTPENSSSPGMMDMHDDNSNQSSIADASPIKQENSSNSSP
. ....:.... .. ..:.... ..:..:.::::: ...: ... . . .
NP_001 RAGGGAERSRGRERR--GRGASPRGGGPLILLDLNDENSNQSFHSEGS-LQKGTEPSPGG
70 80 90 100 110
120 130 140 150 160
pF1KE1 APEPNSAV-PSDGTEAKVDEAQAD--GKEH-PGAEDA--SDEQNSQSSME------HSMN
.:.:. : :. :. .::: :.:. ::. : .:: .. : .. .
NP_001 TPQPSRPVSPAGPPEGVPEEAQPPRLGQERDPGGITAGSTDEPPMLTKEEPVPELLEAED
120 130 140 150 160 170
170 180 190 200 210
pF1KE1 SSEKVDRQPSGDSGLAAETSAISQDLEGVPPSKKMKLEASQQNSEEM
:. .. :. ..:: .:
NP_001 SGVRMTRRALHEKGLKTEPLRRLLPRRGLRTNVRPSSMAVPDTRAPGGGSKAPRAPRTIP
180 190 200 210 220 230
>>XP_011544282 (OMIM: 605847) PREDICTED: B-cell CLL/lymp (293 aa)
initn: 359 init1: 339 opt: 413 Z-score: 333.3 bits: 69.2 E(85289): 7.9e-12
Smith-Waterman score: 413; 43.2% identity (76.5% similar) in 162 aa overlap (1-151:1-159)
10 20 30 40 50 60
pF1KE1 MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKN
:.::.::::::::::::::.:::.:::::.:::.:::::::::::.:::::..:. ...
XP_011 MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERR
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 K-----NKKKGKDEKCGSEVTTPENSSSPGMMDMHDDNSNQSSIADASPIKQENSSNSSP
. ....:.... .. ..:.... ..:..:.::::: ...: ... . . .
XP_011 RAGGGAERSRGRERR--GRGASPRGGGPLILLDLNDENSNQSFHSEGS-LQKGTEPSPGG
70 80 90 100 110
120 130 140 150 160
pF1KE1 APEPNSAV-PSDGTEAKVDEAQAD--GKEH-PGAEDA--SDEQNSQSSMEHSMNSSEKVD
.:.:. : :. :. .::: :.:. ::. : .::
XP_011 TPQPSRPVSPAGPPEGVPEEAQPPRLGQERDPGGITAGSTDEPPMLTKEEPVPELLEAET
120 130 140 150 160 170
170 180 190 200 210
pF1KE1 RQPSGDSGLAAETSAISQDLEGVPPSKKMKLEASQQNSEEM
XP_011 MEMMLDKKQIQAIFLFELKMGHKAVETLRNINNTLGPGTANEHIVQWWFKKFCKEDKSLE
180 190 200 210 220 230
210 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 21:33:44 2016 done: Sun Nov 6 21:33:45 2016
Total Scan time: 6.710 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]