Result of FASTA (omim) for
pFN21AE1240
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1240, 427 aa
1>>>pF1KE1240 427 - 427 aa - 427 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6013+/-0.000499; mu= 15.7574+/- 0.031
mean_var=70.6669+/-14.486, 0's: 0 Z-trim(108.9): 44 B-trim: 470 in 2/49
Lambda= 0.152569
statistics sampled from 16996 (17020) to 16996 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.555), E-opt: 0.2 (0.2), width: 16
Scan time: 8.580
The best scores are: opt bits E(85289)
NP_000010 (OMIM: 203750,607809) acetyl-CoA acetylt ( 427) 2715 607.3 2.4e-173
XP_016873170 (OMIM: 203750,607809) PREDICTED: acet ( 337) 2175 488.4 1.2e-137
XP_006718898 (OMIM: 203750,607809) PREDICTED: acet ( 337) 2175 488.4 1.2e-137
XP_016873172 (OMIM: 203750,607809) PREDICTED: acet ( 301) 1810 408.0 1.6e-113
XP_016873171 (OMIM: 203750,607809) PREDICTED: acet ( 301) 1810 408.0 1.6e-113
NP_005882 (OMIM: 100678,614055) acetyl-CoA acetylt ( 397) 1031 236.6 8.5e-62
NP_001290182 (OMIM: 100678,614055) acetyl-CoA acet ( 426) 991 227.8 4.1e-59
NP_006102 (OMIM: 604770) 3-ketoacyl-CoA thiolase, ( 397) 876 202.5 1.6e-51
NP_001598 (OMIM: 604054) 3-ketoacyl-CoA thiolase, ( 424) 663 155.6 2.2e-37
XP_011531952 (OMIM: 604054) PREDICTED: 3-ketoacyl- ( 279) 506 121.0 3.9e-27
XP_006713186 (OMIM: 604054) PREDICTED: 3-ketoacyl- ( 272) 490 117.5 4.3e-26
NP_001268442 (OMIM: 143450,609015) trifunctional e ( 452) 258 66.5 1.6e-10
NP_000174 (OMIM: 143450,609015) trifunctional enzy ( 474) 257 66.3 1.9e-10
XP_011531105 (OMIM: 143450,609015) PREDICTED: trif ( 474) 257 66.3 1.9e-10
XP_016859428 (OMIM: 143450,609015) PREDICTED: trif ( 481) 257 66.3 1.9e-10
NP_001123882 (OMIM: 604054) 3-ketoacyl-CoA thiolas ( 331) 220 58.1 4e-08
XP_006713185 (OMIM: 604054) PREDICTED: 3-ketoacyl- ( 364) 220 58.1 4.3e-08
NP_001268441 (OMIM: 143450,609015) trifunctional e ( 459) 197 53.1 1.8e-06
>>NP_000010 (OMIM: 203750,607809) acetyl-CoA acetyltrans (427 aa)
initn: 2715 init1: 2715 opt: 2715 Z-score: 3233.2 bits: 607.3 E(85289): 2.4e-173
Smith-Waterman score: 2715; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)
10 20 30 40 50 60
pF1KE1 MAVLAALLRSGARSRSPLLRRLVQEIRYVERSYVSKPTLKEVVIVSATRTPIGSFLGSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MAVLAALLRSGARSRSPLLRRLVQEIRYVERSYVSKPTLKEVVIVSATRTPIGSFLGSLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 KDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 AKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 LANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQGEYGLASICNGGGGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQGEYGLASICNGGGGAS
370 380 390 400 410 420
pF1KE1 AMLIQKL
:::::::
NP_000 AMLIQKL
>>XP_016873170 (OMIM: 203750,607809) PREDICTED: acetyl-C (337 aa)
initn: 2175 init1: 2175 opt: 2175 Z-score: 2592.4 bits: 488.4 E(85289): 1.2e-137
Smith-Waterman score: 2175; 100.0% identity (100.0% similar) in 337 aa overlap (91-427:1-337)
70 80 90 100 110 120
pF1KE1 LLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCT
::::::::::::::::::::::::::::::
XP_016 MGNVLQGGEGQAPTRQAVLGAGLPISTPCT
10 20 30
130 140 150 160 170 180
pF1KE1 TINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIV
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE1 KDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE1 TVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADA
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE1 AKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVV
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE1 LANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQGEYGLASICNGGGGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQGEYGLASICNGGGGAS
280 290 300 310 320 330
pF1KE1 AMLIQKL
:::::::
XP_016 AMLIQKL
>>XP_006718898 (OMIM: 203750,607809) PREDICTED: acetyl-C (337 aa)
initn: 2175 init1: 2175 opt: 2175 Z-score: 2592.4 bits: 488.4 E(85289): 1.2e-137
Smith-Waterman score: 2175; 100.0% identity (100.0% similar) in 337 aa overlap (91-427:1-337)
70 80 90 100 110 120
pF1KE1 LLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCT
::::::::::::::::::::::::::::::
XP_006 MGNVLQGGEGQAPTRQAVLGAGLPISTPCT
10 20 30
130 140 150 160 170 180
pF1KE1 TINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIV
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE1 KDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE1 TVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADA
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE1 AKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVV
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE1 LANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQGEYGLASICNGGGGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQGEYGLASICNGGGGAS
280 290 300 310 320 330
pF1KE1 AMLIQKL
:::::::
XP_006 AMLIQKL
>>XP_016873172 (OMIM: 203750,607809) PREDICTED: acetyl-C (301 aa)
initn: 1810 init1: 1810 opt: 1810 Z-score: 2158.9 bits: 408.0 E(85289): 1.6e-113
Smith-Waterman score: 1810; 100.0% identity (100.0% similar) in 283 aa overlap (145-427:19-301)
120 130 140 150 160 170
pF1KE1 ISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVK
::::::::::::::::::::::::::::::
XP_016 MFYKEVKDKLLQGRQYWVQDVMVAGGMESMSNVPYVMNRGSTPYGGVK
10 20 30 40
180 190 200 210 220 230
pF1KE1 LEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNE
50 60 70 80 90 100
240 250 260 270 280 290
pF1KE1 VIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALV
110 120 130 140 150 160
300 310 320 330 340 350
pF1KE1 LMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNE
170 180 190 200 210 220
360 370 380 390 400 410
pF1KE1 AFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQGEYGLASICN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQGEYGLASICN
230 240 250 260 270 280
420
pF1KE1 GGGGASAMLIQKL
:::::::::::::
XP_016 GGGGASAMLIQKL
290 300
>>XP_016873171 (OMIM: 203750,607809) PREDICTED: acetyl-C (301 aa)
initn: 1810 init1: 1810 opt: 1810 Z-score: 2158.9 bits: 408.0 E(85289): 1.6e-113
Smith-Waterman score: 1810; 100.0% identity (100.0% similar) in 283 aa overlap (145-427:19-301)
120 130 140 150 160 170
pF1KE1 ISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVK
::::::::::::::::::::::::::::::
XP_016 MFYKEVKDKLLQGRQYWVQDVMVAGGMESMSNVPYVMNRGSTPYGGVK
10 20 30 40
180 190 200 210 220 230
pF1KE1 LEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNE
50 60 70 80 90 100
240 250 260 270 280 290
pF1KE1 VIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALV
110 120 130 140 150 160
300 310 320 330 340 350
pF1KE1 LMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNE
170 180 190 200 210 220
360 370 380 390 400 410
pF1KE1 AFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQGEYGLASICN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQGEYGLASICN
230 240 250 260 270 280
420
pF1KE1 GGGGASAMLIQKL
:::::::::::::
XP_016 GGGGASAMLIQKL
290 300
>>NP_005882 (OMIM: 100678,614055) acetyl-CoA acetyltrans (397 aa)
initn: 994 init1: 395 opt: 1031 Z-score: 1230.4 bits: 236.6 E(85289): 8.5e-62
Smith-Waterman score: 1031; 43.8% identity (74.4% similar) in 390 aa overlap (42-426:8-396)
20 30 40 50 60 70
pF1KE1 ARSRSPLLRRLVQEIRYVERSYVSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIA
::::::.:: :::: :.:. .:. ::: .
NP_005 MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTV
10 20 30
80 90 100 110 120 130
pF1KE1 IQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMK
:. ....: . :.:.:. .:.:: .: :: :.::: .:::.: :.: . . .:.::.:
NP_005 IKEVLKRATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLK
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE1 AIMMASQSLMCGHQDVMVAGGMESMSNVPYVMN-RGSTPYGGVKLEDLIVKDGLTDVYNK
:. .: ::. : ....::::::.::..:.. : .. : . : : :. :::::....
NP_005 AVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHN
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE1 IHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVV
::: :::.::: ...:..:: :. : .:.. : .::.: .:..:: :... . . :
NP_005 CHMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTR-KGLIEV
160 170 180 190 200 210
260 270 280 290 300
pF1KE1 KEDEEYKR-VDFSKVPKLKTVFQKEN-GTVTAANASTLNDGAAALVLMTADAAKRLNVTP
: :: .. .. . ::: : .. :::: :::: .::::::.::: . : . ..::
NP_005 KTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTP
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 LARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLE
:::::......::: . :.:. : .... .: . ::. ..:.::::. : : .: :
NP_005 LARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELG
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 IDPQKVNINGGAVSLGHPIGMSGARIVGHLTHAL-KQGE-YGLASICNGGGGASAMLIQK
..:.::::.:::..::::.: :: ::. : :.: ..:. :.:..: ::: . :: .:.
NP_005 LNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQR
340 350 360 370 380 390
pF1KE1 L
NP_005 E
>>NP_001290182 (OMIM: 100678,614055) acetyl-CoA acetyltr (426 aa)
initn: 978 init1: 395 opt: 991 Z-score: 1182.3 bits: 227.8 E(85289): 4.1e-59
Smith-Waterman score: 1000; 41.2% identity (70.9% similar) in 430 aa overlap (2-426:15-425)
10 20 30 40
pF1KE1 MAVLAALLRSGARSRSPLLRRLVQEIRYVERSYVSKPTLKEVVIVSA
:. :.: :::.: :: : :.: ::: .....
NP_001 MGSHPVLRIWGNRRATAASLGRSGGRLSSPRLLRVVA------------PTL---TFAQT
10 20 30 40
50 60 70 80 90 100
pF1KE1 TRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQA
.: :: :.:. .:. ::: .:. ....: . :.:.:. .:.:: .: :: :.:::
NP_001 SRC---SFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQNPVRQA
50 60 70 80 90 100
110 120 130 140 150 160
pF1KE1 VLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMN-RG
.:::.: :.: . . .:.::.::. .: ::. : ....::::::.::..:.. :
NP_001 SVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRT
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE1 STPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAW
.. : . : : :. :::::.... ::: :::.::: ...:..:: :. : .:.. :
NP_001 GVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQ
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE1 EAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKR-VDFSKVPKLKTVFQKEN-GTVTAANAS
.::.: .:..:: :... . . :: :: .. .. . ::: : .. :::: ::::
NP_001 KAGHFDKEIVPVLVSTR-KGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANAS
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE1 TLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKK
.::::::.::: . : . ..:::::::......::: . :.:. : .... .: .
NP_001 GINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSL
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE1 EDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHAL-K
::. ..:.::::. : : .: : ..:.::::.:::..::::.: :: ::. : :.: .
NP_001 EDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLER
350 360 370 380 390 400
410 420
pF1KE1 QGE-YGLASICNGGGGASAMLIQKL
.:. :.:..: ::: . :: .:.
NP_001 MGRSRGVAALCIGGGMGIAMCVQRE
410 420
>>NP_006102 (OMIM: 604770) 3-ketoacyl-CoA thiolase, mito (397 aa)
initn: 657 init1: 401 opt: 876 Z-score: 1046.0 bits: 202.5 E(85289): 1.6e-51
Smith-Waterman score: 876; 41.6% identity (70.1% similar) in 394 aa overlap (39-425:4-394)
10 20 30 40 50 60
pF1KE1 RSGARSRSPLLRRLVQEIRYVERSYVSKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLG
:. : .:.: :::.:.. : :. . :: :.
NP_006 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLS
10 20 30
70 80 90 100 110 120
pF1KE1 SIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAP-TRQAVLGAGLPISTPCTTINKVCA
.: ..:. . . : : . ::::::.. .:.. : .:.: :: :::..:.
NP_006 EFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCG
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 SGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPY-VMN-RGSTPYGG-VKLEDLIVKDGL
::...:. . : . . .:.. :: ::::..:: : : : .: :. .:::: . . :
NP_006 SGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVS-L
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 TDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV-TVK
:: . .. :. ::: : : .:.:.: : ::..: : ::: .:: :..:. :. : : :
NP_006 TDQHVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKK
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 GQPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADAAKR
:. . : : . .. . .. :: ::.:. :::::.::: . :::.:... . ::.:.
NP_006 GKQTMQVDEHAR-PQTTLEQLQKLPPVFKKD-GTVTAGNASGVADGAGAVIIASEDAVKK
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 LNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLAN
: :::::::.. .. .: . :.:: : : .:: .::. .:. . ::::::. ::
NP_006 HNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAV
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 IKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQ--GEYGLASICNGGGGASA
. :..: .:.:.::::..::::.: ::.::..::.: :.. :.:...: : ::: . :
NP_006 ERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIA
340 350 360 370 380 390
pF1KE1 MLIQKL
..::
NP_006 VIIQSTA
>>NP_001598 (OMIM: 604054) 3-ketoacyl-CoA thiolase, pero (424 aa)
initn: 594 init1: 309 opt: 663 Z-score: 792.2 bits: 155.6 E(85289): 2.2e-37
Smith-Waterman score: 663; 33.6% identity (64.9% similar) in 402 aa overlap (32-423:28-419)
10 20 30 40 50 60
pF1KE1 AVLAALLRSGARSRSPLLRRLVQEIRYVERSYVSKPTLKEVVIVSATRTPIG-SFLGSLS
: . . . .::.: . :: : . :...
NP_001 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFK
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 LLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCT
.: : .. .... ... :.. . .::::: : : .: : . . .: ..: .
NP_001 DTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 TINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIV
:.:. :.::..:. . .. : :. .: :.:::: . .::. : : :.
NP_001 TVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS----LADRGN-P--GNITSRLME
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 KDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV
:. : : :: .::.:....:.:..::..:. : .. : : : :..:::.
NP_001 KEKARDCL--IPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTT
180 190 200 210 220
250 260 270 280 290
pF1KE1 TV---KG-QPDVVVKEDEEYK-RVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVL
:: :: . ...: .:: . . . . ::: .:.:. :..::.:.: ..:::::..:
NP_001 TVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD-GSTTAGNSSQVSDGAAAILL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE1 MTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEA
. :..:.. :. . ..: ..: : . :.:.:: ..:. .:: :. ..:.:::
NP_001 ARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEA
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE1 FSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQ-GE--YGLASI
:. . .. :.. :.::: ::::.::::.: .::: : : . ::. :. ::..:.
NP_001 FASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSM
350 360 370 380 390 400
420
pF1KE1 CNGGG-GASAMLIQKL
: : : ::.:..
NP_001 CIGTGMGAAAVFEYPGN
410 420
>>XP_011531952 (OMIM: 604054) PREDICTED: 3-ketoacyl-CoA (279 aa)
initn: 432 init1: 309 opt: 506 Z-score: 608.2 bits: 121.0 E(85289): 3.9e-27
Smith-Waterman score: 506; 37.0% identity (67.6% similar) in 284 aa overlap (149-423:1-274)
120 130 140 150 160 170
pF1KE1 CTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDL
.: :.:::: . .::. : :.. :
XP_011 MACGVESMS----LADRGN-P-GNIT-SRL
10 20
180 190 200 210 220 230
pF1KE1 IVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPV
. :. : : :: .::.:....:.:..::..:. : .. : : : :..::
XP_011 MEKEKARDCL--IPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPV
30 40 50 60 70 80
240 250 260 270 280 290
pF1KE1 TVTV---KG-QPDVVVKEDEEYK-RVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAAL
:.:: :: . ...: .:: . . . . ::: .:.:. :..::.:.: ..:::::.
XP_011 TTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD-GSTTAGNSSQVSDGAAAI
90 100 110 120 130 140
300 310 320 330 340 350
pF1KE1 VLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVN
.: . :..:.. :. . ..: ..: : . :.:.:: ..:. .:: :. ..:.:
XP_011 LLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEIN
150 160 170 180 190 200
360 370 380 390 400 410
pF1KE1 EAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQ-GE--YGLA
:::. . .. :.. :.::: ::::.::::.: .::: : : . ::. :. ::..
XP_011 EAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVV
210 220 230 240 250 260
420
pF1KE1 SICNGGG-GASAMLIQKL
:.: : : ::.:..
XP_011 SMCIGTGMGAAAVFEYPGN
270
427 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 21:37:35 2016 done: Sun Nov 6 21:37:36 2016
Total Scan time: 8.580 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]