Result of FASTA (omim) for
pFN21AE0202
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0202, 268 aa
1>>>pF1KE0202 268 - 268 aa - 268 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.3707+/-0.000471; mu= -6.8517+/- 0.030
mean_var=410.8241+/-84.057, 0's: 0 Z-trim(121.0): 61 B-trim: 450 in 1/55
Lambda= 0.063277
statistics sampled from 36893 (36968) to 36893 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.433), width: 16
Scan time: 8.270
The best scores are: opt bits E(85289)
NP_112182 (OMIM: 609611) acidic leucine-rich nucle ( 268) 1735 171.9 1.1e-42
NP_001267488 (OMIM: 609611) acidic leucine-rich nu ( 267) 1717 170.2 3.4e-42
XP_016857907 (OMIM: 609611) PREDICTED: acidic leuc ( 285) 1482 148.8 1e-35
XP_005245570 (OMIM: 609611) PREDICTED: acidic leuc ( 286) 1482 148.8 1e-35
XP_005245571 (OMIM: 609611) PREDICTED: acidic leuc ( 253) 1463 147.0 3.2e-35
NP_001129951 (OMIM: 609611) acidic leucine-rich nu ( 220) 1425 143.5 3.2e-34
NP_001129950 (OMIM: 609611) acidic leucine-rich nu ( 227) 1088 112.7 6e-25
NP_006296 (OMIM: 600832) acidic leucine-rich nucle ( 249) 906 96.2 6.4e-20
NP_036535 (OMIM: 606877) acidic leucine-rich nucle ( 234) 739 80.9 2.4e-15
NP_001267489 (OMIM: 609611) acidic leucine-rich nu ( 165) 694 76.6 3.3e-14
NP_036536 (OMIM: 606878) acidic leucine-rich nucle ( 131) 544 62.8 3.7e-10
>>NP_112182 (OMIM: 609611) acidic leucine-rich nuclear p (268 aa)
initn: 1735 init1: 1735 opt: 1735 Z-score: 887.3 bits: 171.9 E(85289): 1.1e-42
Smith-Waterman score: 1735; 100.0% identity (100.0% similar) in 268 aa overlap (1-268:1-268)
10 20 30 40 50 60
pF1KE0 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE
190 200 210 220 230 240
250 260
pF1KE0 EEEEEEEGGLRGEKRKRDAEDDGEEEDD
::::::::::::::::::::::::::::
NP_112 EEEEEEEGGLRGEKRKRDAEDDGEEEDD
250 260
>>NP_001267488 (OMIM: 609611) acidic leucine-rich nuclea (267 aa)
initn: 1935 init1: 1609 opt: 1717 Z-score: 878.4 bits: 170.2 E(85289): 3.4e-42
Smith-Waterman score: 1717; 99.6% identity (99.6% similar) in 268 aa overlap (1-268:1-267)
10 20 30 40 50 60
pF1KE0 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE
190 200 210 220 230 240
250 260
pF1KE0 EEEEEEEGGLRGEKRKRDAEDDGEEEDD
:::::: :::::::::::::::::::::
NP_001 EEEEEE-GGLRGEKRKRDAEDDGEEEDD
250 260
>>XP_016857907 (OMIM: 609611) PREDICTED: acidic leucine- (285 aa)
initn: 1604 init1: 1464 opt: 1482 Z-score: 762.2 bits: 148.8 E(85289): 1e-35
Smith-Waterman score: 1671; 93.4% identity (93.4% similar) in 286 aa overlap (1-268:1-285)
10 20 30 40 50 60
pF1KE0 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP
130 140 150 160 170 180
190 200 210 220
pF1KE0 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQ-------------
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQSEKSYGFFNLQTE
190 200 210 220 230 240
230 240 250 260
pF1KE0 -----DEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD
::::::::::::::::::: :::::::::::::::::::::
XP_016 YLNFKDEEDDDDYVEEGEEEEEEE-GGLRGEKRKRDAEDDGEEEDD
250 260 270 280
>>XP_005245570 (OMIM: 609611) PREDICTED: acidic leucine- (286 aa)
initn: 1594 init1: 1464 opt: 1482 Z-score: 762.1 bits: 148.8 E(85289): 1e-35
Smith-Waterman score: 1689; 93.7% identity (93.7% similar) in 286 aa overlap (1-268:1-286)
10 20 30 40 50 60
pF1KE0 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP
130 140 150 160 170 180
190 200 210 220
pF1KE0 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQ-------------
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQSEKSYGFFNLQTE
190 200 210 220 230 240
230 240 250 260
pF1KE0 -----DEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD
:::::::::::::::::::::::::::::::::::::::::
XP_005 YLNFKDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD
250 260 270 280
>>XP_005245571 (OMIM: 609611) PREDICTED: acidic leucine- (253 aa)
initn: 1605 init1: 1463 opt: 1463 Z-score: 753.4 bits: 147.0 E(85289): 3.2e-35
Smith-Waterman score: 1463; 99.1% identity (99.6% similar) in 230 aa overlap (1-230:1-230)
10 20 30 40 50 60
pF1KE0 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE
::::::::::::::::::::::::::::::::::::::::::::::: .:
XP_005 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQKKEVFEGRRGNEM
190 200 210 220 230 240
250 260
pF1KE0 EEEEEEEGGLRGEKRKRDAEDDGEEEDD
XP_005 LKTMERKKMTRSF
250
>>NP_001129951 (OMIM: 609611) acidic leucine-rich nuclea (220 aa)
initn: 1425 init1: 1425 opt: 1425 Z-score: 735.4 bits: 143.5 E(85289): 3.2e-34
Smith-Waterman score: 1425; 100.0% identity (100.0% similar) in 220 aa overlap (49-268:1-220)
20 30 40 50 60 70
pF1KE0 VTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDNIISG
::::::::::::::::::::::::::::::
NP_001 MANVELSSLARLPSLNKLRKLELSDNIISG
10 20 30
80 90 100 110 120 130
pF1KE0 GLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRESIFEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRESIFEL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE0 LQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDE
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE0 DEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRD
160 170 180 190 200 210
260
pF1KE0 AEDDGEEEDD
::::::::::
NP_001 AEDDGEEEDD
220
>>NP_001129950 (OMIM: 609611) acidic leucine-rich nuclea (227 aa)
initn: 1056 init1: 1056 opt: 1088 Z-score: 568.9 bits: 112.7 E(85289): 6e-25
Smith-Waterman score: 1392; 84.7% identity (84.7% similar) in 268 aa overlap (1-268:1-227)
10 20 30 40 50 60
pF1KE0 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL
:::::::: :::::::::::
NP_001 PSLNKLRK-----------------------------------------QNLKNLKSLDL
70
130 140 150 160 170 180
pF1KE0 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP
80 90 100 110 120 130
190 200 210 220 230 240
pF1KE0 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE
140 150 160 170 180 190
250 260
pF1KE0 EEEEEEEGGLRGEKRKRDAEDDGEEEDD
::::::::::::::::::::::::::::
NP_001 EEEEEEEGGLRGEKRKRDAEDDGEEEDD
200 210 220
>>NP_006296 (OMIM: 600832) acidic leucine-rich nuclear p (249 aa)
initn: 1132 init1: 839 opt: 906 Z-score: 478.7 bits: 96.2 E(85289): 6.4e-20
Smith-Waterman score: 958; 59.2% identity (79.0% similar) in 267 aa overlap (1-267:1-249)
10 20 30 40 50 60
pF1KE0 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL
::: ..:.::::::.: .: :::::: .:..:::.: :.:::::: :: :.:.: :
NP_006 MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL
:.::::.::::::: .:::::::::::::::.:::::::::::::.: :..:.:::::::
NP_006 PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP
::::.:::.::::..:.:: :.:::::.:..:.:::::. : .: :::::.:.:
NP_006 FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEG-LDDEEEDEDEEEY
130 140 150 160 170
190 200 210 220 230 240
pF1KE0 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE
: . :.::.:..:.: :.:: .: : :.: : . :..::::.. : ::
NP_006 DEDAQVVEDEEDEDEEEEGEEEDVSGEEE---EDEEGYN---DGEVDDEEDEE---ELGE
180 190 200 210 220 230
250 260
pF1KE0 EEEEEEEGGLRGEKRKRDAEDDGEEEDD
:: ::.::::. ::.::..:
NP_006 EE--------RGQKRKREPEDEGEDDD
240
>>NP_036535 (OMIM: 606877) acidic leucine-rich nuclear p (234 aa)
initn: 843 init1: 475 opt: 739 Z-score: 396.6 bits: 80.9 E(85289): 2.4e-15
Smith-Waterman score: 755; 54.3% identity (71.9% similar) in 256 aa overlap (1-256:1-234)
10 20 30 40 50 60
pF1KE0 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL
::: ..:. :::::.: .: ::.::: .:..:.:.: :.:::::: : :.:.. :
NP_036 MEMGRRIHSELRNRAPSDVKELALDNSRSNEGKLEALTDEFEELEFLSKINGGLTSISDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL
:.: ::::::: .:::::::::::::::.: :::::::::::.: :..:.:::::::
NP_036 PKL-KLRKLELR---VSGGLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLKQLENLKSLDL
70 80 90 100 110
130 140 150 160 170 180
pF1KE0 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP
::::.:::.:: :..:.:: :.::::. . .::: :. :: .: ::::: :.:
NP_036 FNCEVTNLNDYGENVFKLLLQLTYLDSCYWDHKEAPYSDIEDHVEG-LDDEEEGEHEEEY
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE
: . :.:: ::.:.: :.:: .: :.:: ::: .: .::
NP_036 DEDAQVVEDEEGEEEEEEGEEEDVSG-----GDEE------------DEEGYNDGEVDGE
180 190 200 210
250 260
pF1KE0 EEEEEEEGGLRGEKRKRDAEDDGEEEDD
:.::: ::.:::
NP_036 EDEEELGEEERGQKRK
220 230
>>NP_001267489 (OMIM: 609611) acidic leucine-rich nuclea (165 aa)
initn: 711 init1: 694 opt: 694 Z-score: 376.2 bits: 76.6 E(85289): 3.3e-14
Smith-Waterman score: 694; 95.7% identity (98.3% similar) in 116 aa overlap (1-116:1-116)
10 20 30 40 50 60
pF1KE0 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL
:::::::::::::::::::::::::::::::::::::::::::::::::. .: .:
NP_001 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALMAMKMMKRKRK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP
NP_001 MKLVHRKDMRKRRRKRKRRMRMRMKMKMKQVQSWEREKRKWASHT
130 140 150 160
268 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 21:29:54 2016 done: Thu Nov 3 21:29:55 2016
Total Scan time: 8.270 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]