Result of FASTA (omim) for
pFN21AE1879
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1879, 404 aa
1>>>pF1KE1879 404 - 404 aa - 404 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6348+/-0.000358; mu= 15.4227+/- 0.023
mean_var=72.6627+/-14.571, 0's: 0 Z-trim(115.2): 48 B-trim: 238 in 1/54
Lambda= 0.150459
statistics sampled from 25418 (25466) to 25418 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.299), width: 16
Scan time: 7.490
The best scores are: opt bits E(85289)
XP_016869448 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 2713 598.1 1.2e-170
XP_016869447 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 2713 598.1 1.2e-170
NP_477097 (OMIM: 603775) G1/S-specific cyclin-E2 [ ( 404) 2713 598.1 1.2e-170
XP_016869446 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 2713 598.1 1.2e-170
XP_011515668 (OMIM: 603775) PREDICTED: G1/S-specif ( 288) 1864 413.7 2.8e-115
XP_011525742 (OMIM: 123837) PREDICTED: G1/S-specif ( 407) 1233 276.8 6.4e-74
NP_001309191 (OMIM: 123837) G1/S-specific cyclin-E ( 395) 1231 276.4 8.4e-74
NP_001229 (OMIM: 123837) G1/S-specific cyclin-E1 i ( 410) 1231 276.4 8.7e-74
NP_001309190 (OMIM: 123837) G1/S-specific cyclin-E ( 361) 727 167.0 6.7e-41
NP_001309188 (OMIM: 123837) G1/S-specific cyclin-E ( 365) 680 156.8 8e-38
XP_011533598 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 331 81.1 5.7e-15
XP_011533596 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 331 81.1 5.7e-15
XP_011533597 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 331 81.1 5.7e-15
NP_001104517 (OMIM: 604036) cyclin-A1 isoform c [H ( 421) 331 81.1 5.7e-15
NP_001104516 (OMIM: 604036) cyclin-A1 isoform c [H ( 421) 331 81.1 5.7e-15
NP_001104515 (OMIM: 604036) cyclin-A1 isoform b [H ( 464) 331 81.1 6.2e-15
NP_003905 (OMIM: 604036) cyclin-A1 isoform a [Homo ( 465) 331 81.1 6.2e-15
NP_001228 (OMIM: 123835) cyclin-A2 [Homo sapiens] ( 432) 320 78.7 3.1e-14
NP_001751 (OMIM: 123834) G1/S-specific cyclin-D3 i ( 292) 306 75.6 1.8e-13
NP_004692 (OMIM: 602755) G2/mitotic-specific cycli ( 398) 307 75.8 2e-13
NP_444284 (OMIM: 168461,193300,254500) G1/S-specif ( 295) 302 74.7 3.3e-13
XP_011513273 (OMIM: 123834) PREDICTED: G1/S-specif ( 276) 297 73.6 6.7e-13
NP_114172 (OMIM: 123836) G2/mitotic-specific cycli ( 433) 299 74.1 7.3e-13
NP_001750 (OMIM: 123833,615938) G1/S-specific cycl ( 289) 295 73.2 9.4e-13
XP_016885407 (OMIM: 300456) PREDICTED: G2/mitotic- (1395) 254 64.6 1.7e-09
NP_149020 (OMIM: 300456) G2/mitotic-specific cycli (1395) 254 64.6 1.7e-09
XP_016885406 (OMIM: 300456) PREDICTED: G2/mitotic- (1396) 254 64.6 1.7e-09
XP_016885405 (OMIM: 300456) PREDICTED: G2/mitotic- (1403) 250 63.7 3.1e-09
XP_016885402 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 250 63.7 3.1e-09
XP_016885404 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 250 63.7 3.1e-09
XP_016885403 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 250 63.7 3.1e-09
NP_066970 (OMIM: 607752,615872) cyclin-O [Homo sap ( 350) 235 60.2 9.2e-09
NP_001274356 (OMIM: 123834) G1/S-specific cyclin-D ( 242) 202 52.9 9.7e-07
XP_011530701 (OMIM: 603203) PREDICTED: cyclin-G2 i ( 344) 180 48.2 3.6e-05
NP_004345 (OMIM: 603203) cyclin-G2 [Homo sapiens] ( 344) 180 48.2 3.6e-05
XP_011530700 (OMIM: 603203) PREDICTED: cyclin-G2 i ( 344) 180 48.2 3.6e-05
NP_391990 (OMIM: 300456) G2/mitotic-specific cycli ( 291) 177 47.6 4.9e-05
NP_001752 (OMIM: 600227) cyclin-F isoform 1 [Homo ( 786) 175 47.3 0.00015
XP_016879311 (OMIM: 600227) PREDICTED: cyclin-F is ( 867) 175 47.4 0.00017
NP_001129489 (OMIM: 123834) G1/S-specific cyclin-D ( 211) 164 44.7 0.00026
NP_001310467 (OMIM: 600227) cyclin-F isoform 2 [Ho ( 478) 163 44.6 0.00061
NP_004051 (OMIM: 601578) cyclin-G1 [Homo sapiens] ( 295) 160 43.9 0.00063
NP_954854 (OMIM: 601578) cyclin-G1 [Homo sapiens] ( 295) 160 43.9 0.00063
XP_011513274 (OMIM: 123834) PREDICTED: G1/S-specif ( 195) 155 42.7 0.00095
>>XP_016869448 (OMIM: 603775) PREDICTED: G1/S-specific c (404 aa)
initn: 2713 init1: 2713 opt: 2713 Z-score: 3184.3 bits: 598.1 E(85289): 1.2e-170
Smith-Waterman score: 2713; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404)
10 20 30 40 50 60
pF1KE1 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 NKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 LCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTH
310 320 330 340 350 360
370 380 390 400
pF1KE1 TNYLAMLEEVNYINTFRKGGQLSPVCNGGIMTPPKSTEKPPGKH
::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNYLAMLEEVNYINTFRKGGQLSPVCNGGIMTPPKSTEKPPGKH
370 380 390 400
>>XP_016869447 (OMIM: 603775) PREDICTED: G1/S-specific c (404 aa)
initn: 2713 init1: 2713 opt: 2713 Z-score: 3184.3 bits: 598.1 E(85289): 1.2e-170
Smith-Waterman score: 2713; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404)
10 20 30 40 50 60
pF1KE1 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 NKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 LCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTH
310 320 330 340 350 360
370 380 390 400
pF1KE1 TNYLAMLEEVNYINTFRKGGQLSPVCNGGIMTPPKSTEKPPGKH
::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNYLAMLEEVNYINTFRKGGQLSPVCNGGIMTPPKSTEKPPGKH
370 380 390 400
>>NP_477097 (OMIM: 603775) G1/S-specific cyclin-E2 [Homo (404 aa)
initn: 2713 init1: 2713 opt: 2713 Z-score: 3184.3 bits: 598.1 E(85289): 1.2e-170
Smith-Waterman score: 2713; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404)
10 20 30 40 50 60
pF1KE1 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_477 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_477 VLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_477 ESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 NKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_477 NKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_477 VTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 LCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_477 LCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTH
310 320 330 340 350 360
370 380 390 400
pF1KE1 TNYLAMLEEVNYINTFRKGGQLSPVCNGGIMTPPKSTEKPPGKH
::::::::::::::::::::::::::::::::::::::::::::
NP_477 TNYLAMLEEVNYINTFRKGGQLSPVCNGGIMTPPKSTEKPPGKH
370 380 390 400
>>XP_016869446 (OMIM: 603775) PREDICTED: G1/S-specific c (404 aa)
initn: 2713 init1: 2713 opt: 2713 Z-score: 3184.3 bits: 598.1 E(85289): 1.2e-170
Smith-Waterman score: 2713; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404)
10 20 30 40 50 60
pF1KE1 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 NKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 LCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTH
310 320 330 340 350 360
370 380 390 400
pF1KE1 TNYLAMLEEVNYINTFRKGGQLSPVCNGGIMTPPKSTEKPPGKH
::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNYLAMLEEVNYINTFRKGGQLSPVCNGGIMTPPKSTEKPPGKH
370 380 390 400
>>XP_011515668 (OMIM: 603775) PREDICTED: G1/S-specific c (288 aa)
initn: 1864 init1: 1864 opt: 1864 Z-score: 2190.6 bits: 413.7 E(85289): 2.8e-115
Smith-Waterman score: 1864; 99.6% identity (100.0% similar) in 279 aa overlap (1-279:1-279)
10 20 30 40 50 60
pF1KE1 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 NKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAA
::::::::::::::::::::::::::::::::::::::.
XP_011 VTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLFSHFSYLLDQ
250 260 270 280
310 320 330 340 350 360
pF1KE1 LCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTH
>>XP_011525742 (OMIM: 123837) PREDICTED: G1/S-specific c (407 aa)
initn: 1220 init1: 1198 opt: 1233 Z-score: 1448.1 bits: 276.8 E(85289): 6.4e-74
Smith-Waterman score: 1233; 51.9% identity (75.1% similar) in 378 aa overlap (29-399:27-399)
10 20 30 40 50
pF1KE1 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWP-
...:::.. : ::..: . .:
XP_011 MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVDPD-EEMAKIDRTARDQCGSQ
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 PVLSGGI--SPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPS---PLPDLSWGCSKEVW
: .... .:: .: :: :: .: . : : .: :: ::: :::. .:::
XP_011 PWDNNAVCADPCSLIPTPDKE---DDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVW
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 LNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFM
::.::. :..:.:: : :.:.::.::::::.:::::: :::::::::::::::.:
XP_011 KIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYM
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 LTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKAL
::... :..::::::.:::::.:::::: :::..:::::::::: ..:: :::.:.:::
XP_011 ATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKAL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 KWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYR
::.: :.::.::::...:: :.: .:::::: :. :::::.:::::.: .: ::: :
XP_011 KWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 ILTAAALCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDR
::.:.:: ::.: :...:.:: .: .: .:: :::::. :.. :. ::: :. . ::
XP_011 ILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDA
300 310 320 330 340 350
360 370 380 390 400
pF1KE1 HNIQTHTNYLAMLEEVNYINT-FRKGGQLSPVCNGGIMTPPKSTEKPPGKH
:::::: . : .:... .. . . .. ::. .:..:::.: .:
XP_011 HNIQTHRDSLDLLDKARAKKAMLSEQNRASPL-PSGLLTPPQSGKKQSSGPEMA
360 370 380 390 400
>>NP_001309191 (OMIM: 123837) G1/S-specific cyclin-E1 is (395 aa)
initn: 1220 init1: 1198 opt: 1231 Z-score: 1445.9 bits: 276.4 E(85289): 8.4e-74
Smith-Waterman score: 1231; 51.6% identity (75.0% similar) in 380 aa overlap (29-399:12-387)
10 20 30 40 50
pF1KE1 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDV--KKRREEVTKKHQYEIRNCW
...:::.. : . ::..: . .:
NP_001 MKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCG
10 20 30 40
60 70 80 90 100 110
pF1KE1 P-PVLSGGI--SPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPS---PLPDLSWGCSKE
: .... .:: .: :: :: .: . : : .: :: ::: :::. .:
NP_001 SQPWDNNAVCADPCSLIPTPDKE---DDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREE
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE1 VWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDR
:: ::.::. :..:.:: : :.:.::.::::::.:::::: :::::::::::::::
NP_001 VWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE1 FMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILK
.: ::... :..::::::.:::::.:::::: :::..:::::::::: ..:: :::.:.:
NP_001 YMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMK
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE1 ALKWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQ
::::.: :.::.::::...:: :.: .:::::: :. :::::.:::::.: .: :::
NP_001 ALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFP
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE1 YRILTAAALCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPME
: ::.:.:: ::.: :...:.:: .: .: .:: :::::. :.. :. ::: :. . :
NP_001 YGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADE
290 300 310 320 330 340
360 370 380 390 400
pF1KE1 DRHNIQTHTNYLAMLEEVNYINT-FRKGGQLSPVCNGGIMTPPKSTEKPPGKH
: :::::: . : .:... .. . . .. ::. .:..:::.: .:
NP_001 DAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPL-PSGLLTPPQSGKKQSSGPEMA
350 360 370 380 390
>>NP_001229 (OMIM: 123837) G1/S-specific cyclin-E1 isofo (410 aa)
initn: 1220 init1: 1198 opt: 1231 Z-score: 1445.7 bits: 276.4 E(85289): 8.7e-74
Smith-Waterman score: 1231; 51.6% identity (75.0% similar) in 380 aa overlap (29-399:27-402)
10 20 30 40 50
pF1KE1 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDV--KKRREEVTKKHQYEIRNCW
...:::.. : . ::..: . .:
NP_001 MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCG
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 P-PVLSGGI--SPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPS---PLPDLSWGCSKE
: .... .:: .: :: :: .: . : : .: :: ::: :::. .:
NP_001 SQPWDNNAVCADPCSLIPTPDKE---DDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 VWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDR
:: ::.::. :..:.:: : :.:.::.::::::.:::::: :::::::::::::::
NP_001 VWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 FMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILK
.: ::... :..::::::.:::::.:::::: :::..:::::::::: ..:: :::.:.:
NP_001 YMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 ALKWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQ
::::.: :.::.::::...:: :.: .:::::: :. :::::.:::::.: .: :::
NP_001 ALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 YRILTAAALCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPME
: ::.:.:: ::.: :...:.:: .: .: .:: :::::. :.. :. ::: :. . :
NP_001 YGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADE
300 310 320 330 340 350
360 370 380 390 400
pF1KE1 DRHNIQTHTNYLAMLEEVNYINT-FRKGGQLSPVCNGGIMTPPKSTEKPPGKH
: :::::: . : .:... .. . . .. ::. .:..:::.: .:
NP_001 DAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPL-PSGLLTPPQSGKKQSSGPEMA
360 370 380 390 400 410
>>NP_001309190 (OMIM: 123837) G1/S-specific cyclin-E1 is (361 aa)
initn: 935 init1: 717 opt: 727 Z-score: 855.3 bits: 167.0 E(85289): 6.7e-41
Smith-Waterman score: 865; 41.6% identity (62.9% similar) in 380 aa overlap (29-399:27-353)
10 20 30 40 50
pF1KE1 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDV--KKRREEVTKKHQYEIRNCW
...:::.. : . ::..: . .:
NP_001 MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCG
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 P-PVLSGGI--SPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPS---PLPDLSWGCSKE
: .... .:: .: :: :: .: . : : .: :: ::: :::. .:
NP_001 SQPWDNNAVCADPCSLIPTPDKE---DDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 VWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDR
:: ::.::. :..:.:: : :.:.::.::::::.:
NP_001 VWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLME---------------------
120 130 140 150
180 190 200 210 220 230
pF1KE1 FMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILK
::: :::..:::::::::: ..:: :::.:.:
NP_001 ----------------------------EIYPPKLHQFAYVTDGACSGDEILTMELMIMK
160 170 180
240 250 260 270 280 290
pF1KE1 ALKWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQ
::::.: :.::.::::...:: :.: .:::::: :. :::::.:::::.: .: :::
NP_001 ALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFP
190 200 210 220 230 240
300 310 320 330 340 350
pF1KE1 YRILTAAALCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPME
: ::.:.:: ::.: :...:.:: .: .: .:: :::::. :.. :. ::: :. . :
NP_001 YGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADE
250 260 270 280 290 300
360 370 380 390 400
pF1KE1 DRHNIQTHTNYLAMLEEVNYINT-FRKGGQLSPVCNGGIMTPPKSTEKPPGKH
: :::::: . : .:... .. . . .. ::. .:..:::.: .:
NP_001 DAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPL-PSGLLTPPQSGKKQSSGPEMA
310 320 330 340 350 360
>>NP_001309188 (OMIM: 123837) G1/S-specific cyclin-E1 is (365 aa)
initn: 990 init1: 646 opt: 680 Z-score: 800.1 bits: 156.8 E(85289): 8e-38
Smith-Waterman score: 934; 44.2% identity (65.0% similar) in 380 aa overlap (29-399:27-357)
10 20 30 40 50
pF1KE1 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDV--KKRREEVTKKHQYEIRNCW
...:::.. : . ::..: . .:
NP_001 MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCG
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 P-PVLSGGI--SPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPS---PLPDLSWGCSKE
: .... .:: .: :: :: .: . : : .: :: ::: :::. .:
NP_001 SQPWDNNAVCADPCSLIPTPDKE---DDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 VWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDR
:: ::.::. :..:.:: : :.:.::.::::::.:::::: :::::::::::::::
NP_001 VWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 FMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILK
.: ::... :..::::::.:::::.:::::: :::..:::::::::: ..:: :::.:.:
NP_001 YMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 ALKWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQ
:::::.: .: :::
NP_001 ---------------------------------------------LLDLCVLDVDCLEFP
240 250
300 310 320 330 340 350
pF1KE1 YRILTAAALCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPME
: ::.:.:: ::.: :...:.:: .: .: .:: :::::. :.. :. ::: :. . :
NP_001 YGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADE
260 270 280 290 300 310
360 370 380 390 400
pF1KE1 DRHNIQTHTNYLAMLEEVNYINT-FRKGGQLSPVCNGGIMTPPKSTEKPPGKH
: :::::: . : .:... .. . . .. ::. .:..:::.: .:
NP_001 DAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPL-PSGLLTPPQSGKKQSSGPEMA
320 330 340 350 360
404 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 21:51:19 2016 done: Sun Nov 6 21:51:21 2016
Total Scan time: 7.490 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]