Result of FASTA (omim) for
pFN21AE0092
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0092, 1905 aa
1>>>pF1KE0092 1905 - 1905 aa - 1905 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.9896+/-0.000497; mu= -22.1894+/- 0.031
mean_var=536.5087+/-110.072, 0's: 0 Z-trim(121.4): 111 B-trim: 0 in 0/61
Lambda= 0.055371
statistics sampled from 37920 (38037) to 37920 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.752), E-opt: 0.2 (0.446), width: 16
Scan time: 21.090
The best scores are: opt bits E(85289)
NP_038477 (OMIM: 605682) bromodomain adjacent to z (1905) 12851 1043.1 0
NP_001287834 (OMIM: 605682) bromodomain adjacent t (1903) 12838 1042.1 0
XP_011536100 (OMIM: 605682) PREDICTED: bromodomain (1904) 12832 1041.6 0
XP_011536103 (OMIM: 605682) PREDICTED: bromodomain (1912) 12827 1041.2 0
XP_011536102 (OMIM: 605682) PREDICTED: bromodomain (1931) 12820 1040.6 0
XP_011536105 (OMIM: 605682) PREDICTED: bromodomain (1910) 12814 1040.2 0
XP_011536107 (OMIM: 605682) PREDICTED: bromodomain (1910) 12814 1040.2 0
XP_011536106 (OMIM: 605682) PREDICTED: bromodomain (1910) 12814 1040.2 0
XP_016874230 (OMIM: 605682) PREDICTED: bromodomain (1910) 12814 1040.2 0
XP_016874229 (OMIM: 605682) PREDICTED: bromodomain (1910) 12814 1040.2 0
XP_011536108 (OMIM: 605682) PREDICTED: bromodomain (1910) 12814 1040.2 0
XP_011536099 (OMIM: 605682) PREDICTED: bromodomain (1911) 12808 1039.7 0
XP_016874231 (OMIM: 605682) PREDICTED: bromodomain (1873) 11446 930.9 0
XP_011536101 (OMIM: 605682) PREDICTED: bromodomain (1882) 11422 929.0 0
XP_011536111 (OMIM: 605682) PREDICTED: bromodomain (1362) 9127 745.5 8.2e-214
XP_011536109 (OMIM: 605682) PREDICTED: bromodomain (1834) 7428 609.9 7.6e-173
XP_016859425 (OMIM: 605683) PREDICTED: bromodomain (2015) 909 89.1 4.8e-16
XP_016859421 (OMIM: 605683) PREDICTED: bromodomain (2113) 909 89.2 5e-16
XP_016859420 (OMIM: 605683) PREDICTED: bromodomain (2140) 909 89.2 5e-16
XP_011509353 (OMIM: 605683) PREDICTED: bromodomain (2141) 909 89.2 5e-16
XP_016859419 (OMIM: 605683) PREDICTED: bromodomain (2142) 909 89.2 5e-16
NP_001316787 (OMIM: 605683) bromodomain adjacent t (2143) 909 89.2 5e-16
NP_001316786 (OMIM: 605683) bromodomain adjacent t (2149) 909 89.2 5e-16
XP_016859415 (OMIM: 605683) PREDICTED: bromodomain (2175) 909 89.2 5.1e-16
XP_011509346 (OMIM: 605683) PREDICTED: bromodomain (2178) 909 89.2 5.1e-16
XP_016859412 (OMIM: 605683) PREDICTED: bromodomain (2212) 909 89.2 5.2e-16
XP_011509340 (OMIM: 605683) PREDICTED: bromodomain (2240) 909 89.2 5.2e-16
XP_011509358 (OMIM: 605683) PREDICTED: bromodomain (1426) 900 88.3 5.9e-16
NP_001276904 (OMIM: 605683) bromodomain adjacent t (2132) 904 88.8 6.6e-16
NP_038478 (OMIM: 605683) bromodomain adjacent to z (2168) 904 88.8 6.7e-16
XP_011509345 (OMIM: 605683) PREDICTED: bromodomain (2197) 904 88.8 6.8e-16
XP_011509341 (OMIM: 605683) PREDICTED: bromodomain (2231) 904 88.8 6.9e-16
XP_011509356 (OMIM: 605683) PREDICTED: bromodomain (1976) 900 88.4 7.7e-16
XP_011509355 (OMIM: 605683) PREDICTED: bromodomain (2036) 900 88.4 7.9e-16
XP_016859424 (OMIM: 605683) PREDICTED: bromodomain (2047) 900 88.4 8e-16
XP_016859423 (OMIM: 605683) PREDICTED: bromodomain (2079) 900 88.4 8.1e-16
XP_016859422 (OMIM: 605683) PREDICTED: bromodomain (2081) 900 88.4 8.1e-16
XP_011509354 (OMIM: 605683) PREDICTED: bromodomain (2110) 900 88.4 8.2e-16
XP_011509352 (OMIM: 605683) PREDICTED: bromodomain (2142) 900 88.4 8.3e-16
XP_016859417 (OMIM: 605683) PREDICTED: bromodomain (2144) 900 88.4 8.3e-16
XP_011509347 (OMIM: 605683) PREDICTED: bromodomain (2177) 900 88.4 8.4e-16
XP_011509349 (OMIM: 605683) PREDICTED: bromodomain (2179) 900 88.4 8.4e-16
XP_011509350 (OMIM: 605683) PREDICTED: bromodomain (2179) 900 88.4 8.4e-16
XP_016859413 (OMIM: 605683) PREDICTED: bromodomain (2206) 900 88.4 8.5e-16
XP_011509344 (OMIM: 605683) PREDICTED: bromodomain (2207) 900 88.4 8.5e-16
XP_016859414 (OMIM: 605683) PREDICTED: bromodomain (2208) 900 88.5 8.5e-16
XP_016859410 (OMIM: 605683) PREDICTED: bromodomain (2240) 900 88.5 8.6e-16
XP_005246549 (OMIM: 605683) PREDICTED: bromodomain (2240) 900 88.5 8.6e-16
XP_016859411 (OMIM: 605683) PREDICTED: bromodomain (2240) 900 88.5 8.6e-16
XP_005246545 (OMIM: 605683) PREDICTED: bromodomain (2242) 900 88.5 8.6e-16
>>NP_038477 (OMIM: 605682) bromodomain adjacent to zinc (1905 aa)
initn: 12851 init1: 12851 opt: 12851 Z-score: 5565.2 bits: 1043.1 E(85289): 0
Smith-Waterman score: 12851; 100.0% identity (100.0% similar) in 1905 aa overlap (1-1905:1-1905)
10 20 30 40 50 60
pF1KE0 MEMEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 MEMEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLST
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 VSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 YPLNGILGGSRQPSSPSHNTNLRAGSQEFWANGTQSPMGLNFDSQELYDSFPDQNFEVMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 YPLNGILGGSRQPSSPSHNTNLRAGSQEFWANGTQSPMGLNFDSQELYDSFPDQNFEVMP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 NGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 NGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 EEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDPSHLPDQLEDTPILSEDSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 EEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDPSHLPDQLEDTPILSEDSLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 PFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNNATAFSLLADDSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 PFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNNATAFSLLADDSQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 STSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 STSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTIQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 LHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 SLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEGLTASGSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 SLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEGLTASGSGD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 VMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 VMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 VVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 VVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 AKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQETLNEEDKAKIAKSKKKMRQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 AKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQETLNEEDKAKIAKSKKKMRQK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 VQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 VQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 KMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 KMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 VPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGVLQEGLLCQGDSLGEVQDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 VPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGVLQEGLLCQGDSLGEVQDLL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 VRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEILRCFLMAYGVEPALCDRLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 VRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEILRCFLMAYGVEPALCDRLRT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 QPFQAQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSSYRKNKWIVEGRLRRLKTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 QPFQAQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSSYRKNKWIVEGRLRRLKTVL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE0 AKRTGRSEVEMEGPEECLGRRRSSRIMEETSGMEEEEEEESIAAVPGRRGRRDGEVDATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 AKRTGRSEVEMEGPEECLGRRRSSRIMEETSGMEEEEEEESIAAVPGRRGRRDGEVDATA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE0 SSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRYRRRYWVLPYLAGIFVEGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 SSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRYRRRYWVLPYLAGIFVEGTE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE0 GNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTTASSPARARGRPRKTKPGSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 GNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTTASSPARARGRPRKTKPGSM
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE0 QPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQLQSHKGFLEQEGSPLSLGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 QPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQLQSHKGFLEQEGSPLSLGQS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE0 QHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPPEEPEPDEAESSPDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 QHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPPEEPEPDEAESSPDPQ
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE0 ALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 ALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLA
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE0 GLAPKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVPPEMCSGWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 GLAPKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVPPEMCSGWW
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE0 WIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCLRPSADPIFEPRQLPAFQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 WIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCLRPSADPIFEPRQLPAFQEG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE0 IMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCPSPDSTREDLAYCEHLSDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 IMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCPSPDSTREDLAYCEHLSDSQ
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE0 EDITWRGRGREGLAPQRKTTNPLDLAVMRLAALEQNVERRYLREPLWPTHEVVLEKALLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 EDITWRGRGREGLAPQRKTTNPLDLAVMRLAALEQNVERRYLREPLWPTHEVVLEKALLS
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE0 TPNGAPEGTTTEISYEITPRIRVWRQTLERCRSAAQVCLCLGQLERSIAWEKSVNKVTCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 TPNGAPEGTTTEISYEITPRIRVWRQTLERCRSAAQVCLCLGQLERSIAWEKSVNKVTCL
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE0 VCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQVEGEFTQKPGFPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 VCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQVEGEFTQKPGFPK
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE0 RGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMRNHHSDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 RGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMRNHHSDLT
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE0 FCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 FCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAA
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900
pF1KE0 DALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQANL
:::::::::::::::::::::::::::::::::::::::::::::
NP_038 DALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQANL
1870 1880 1890 1900
>>NP_001287834 (OMIM: 605682) bromodomain adjacent to zi (1903 aa)
initn: 12838 init1: 12838 opt: 12838 Z-score: 5559.6 bits: 1042.1 E(85289): 0
Smith-Waterman score: 12838; 100.0% identity (100.0% similar) in 1903 aa overlap (3-1905:1-1903)
10 20 30 40 50 60
pF1KE0 MEMEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLST
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 VSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 YPLNGILGGSRQPSSPSHNTNLRAGSQEFWANGTQSPMGLNFDSQELYDSFPDQNFEVMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPLNGILGGSRQPSSPSHNTNLRAGSQEFWANGTQSPMGLNFDSQELYDSFPDQNFEVMP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 NGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLEL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 EEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDPSHLPDQLEDTPILSEDSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDPSHLPDQLEDTPILSEDSLE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE0 PFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNNATAFSLLADDSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNNATAFSLLADDSQT
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE0 STSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTIQ
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE0 LHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAV
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE0 SLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEGLTASGSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEGLTASGSGD
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE0 VMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRN
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE0 VVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEK
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE0 AKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQETLNEEDKAKIAKSKKKMRQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQETLNEEDKAKIAKSKKKMRQK
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE0 VQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKV
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE0 KMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSR
780 790 800 810 820 830
850 860 870 880 890 900
pF1KE0 VPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGVLQEGLLCQGDSLGEVQDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGVLQEGLLCQGDSLGEVQDLL
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE0 VRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEILRCFLMAYGVEPALCDRLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEILRCFLMAYGVEPALCDRLRT
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE0 QPFQAQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSSYRKNKWIVEGRLRRLKTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPFQAQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSSYRKNKWIVEGRLRRLKTVL
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KE0 AKRTGRSEVEMEGPEECLGRRRSSRIMEETSGMEEEEEEESIAAVPGRRGRRDGEVDATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKRTGRSEVEMEGPEECLGRRRSSRIMEETSGMEEEEEEESIAAVPGRRGRRDGEVDATA
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KE0 SSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRYRRRYWVLPYLAGIFVEGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRYRRRYWVLPYLAGIFVEGTE
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KE0 GNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTTASSPARARGRPRKTKPGSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTTASSPARARGRPRKTKPGSM
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KE0 QPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQLQSHKGFLEQEGSPLSLGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQLQSHKGFLEQEGSPLSLGQS
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KE0 QHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPPEEPEPDEAESSPDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPPEEPEPDEAESSPDPQ
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KE0 ALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLA
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KE0 GLAPKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVPPEMCSGWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLAPKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVPPEMCSGWW
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KE0 WIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCLRPSADPIFEPRQLPAFQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCLRPSADPIFEPRQLPAFQEG
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KE0 IMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCPSPDSTREDLAYCEHLSDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCPSPDSTREDLAYCEHLSDSQ
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KE0 EDITWRGRGREGLAPQRKTTNPLDLAVMRLAALEQNVERRYLREPLWPTHEVVLEKALLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDITWRGRGREGLAPQRKTTNPLDLAVMRLAALEQNVERRYLREPLWPTHEVVLEKALLS
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670 1680
pF1KE0 TPNGAPEGTTTEISYEITPRIRVWRQTLERCRSAAQVCLCLGQLERSIAWEKSVNKVTCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPNGAPEGTTTEISYEITPRIRVWRQTLERCRSAAQVCLCLGQLERSIAWEKSVNKVTCL
1620 1630 1640 1650 1660 1670
1690 1700 1710 1720 1730 1740
pF1KE0 VCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQVEGEFTQKPGFPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQVEGEFTQKPGFPK
1680 1690 1700 1710 1720 1730
1750 1760 1770 1780 1790 1800
pF1KE0 RGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMRNHHSDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMRNHHSDLT
1740 1750 1760 1770 1780 1790
1810 1820 1830 1840 1850 1860
pF1KE0 FCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAA
1800 1810 1820 1830 1840 1850
1870 1880 1890 1900
pF1KE0 DALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQANL
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 DALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQANL
1860 1870 1880 1890 1900
>>XP_011536100 (OMIM: 605682) PREDICTED: bromodomain adj (1904 aa)
initn: 11627 init1: 11627 opt: 12832 Z-score: 5557.0 bits: 1041.6 E(85289): 0
Smith-Waterman score: 12832; 99.9% identity (99.9% similar) in 1905 aa overlap (1-1905:1-1904)
10 20 30 40 50 60
pF1KE0 MEMEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEMEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLST
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 YPLNGILGGSRQPSSPSHNTNLRAGSQEFWANGTQSPMGLNFDSQELYDSFPDQNFEVMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPLNGILGGSRQPSSPSHNTNLRAGSQEFWANGTQSPMGLNFDSQELYDSFPDQNFEVMP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 NGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 EEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDPSHLPDQLEDTPILSEDSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDPSHLPDQLEDTPILSEDSLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 PFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNNATAFSLLADDSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNNATAFSLLADDSQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 STSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTIQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 SLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEGLTASGSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEGLTASGSGD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 VMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 VVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 AKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQETLNEEDKAKIAKSKKKMRQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQETLNEEDKAKIAKSKKKMRQK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 VQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 KMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 VPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGVLQEGLLCQGDSLGEVQDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGVLQEGLLCQGDSLGEVQDLL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 VRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEILRCFLMAYGVEPALCDRLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEILRCFLMAYGVEPALCDRLRT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 QPFQAQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSSYRKNKWIVEGRLRRLKTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPFQAQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSSYRKNKWIVEGRLRRLKTVL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE0 AKRTGRSEVEMEGPEECLGRRRSSRIMEETSGMEEEEEEESIAAVPGRRGRRDGEVDATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKRTGRSEVEMEGPEECLGRRRSSRIMEETSGMEEEEEEESIAAVPGRRGRRDGEVDATA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE0 SSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRYRRRYWVLPYLAGIFVEGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRYRRRYWVLPYLAGIFVEGTE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE0 GNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTTASSPARARGRPRKTKPGSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTTASSPARARGRPRKTKPGSM
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE0 QPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQLQSHKGFLEQEGSPLSLGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQLQSHKGFLEQEGSPLSLGQS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE0 QHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPPEEPEPDEAESSPDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPPEEPEPDEAESSPDPQ
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE0 ALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLA
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE0 GLAPKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVPPEMCSGWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLAPKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVPPEMCSGWW
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE0 WIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCLRPSADPIFEPRQLPAFQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCLRPSADPIFEPRQLPAFQEG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE0 IMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCPSPDSTREDLAYCEHLSDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCPSPDSTREDLAYCEHLSDSQ
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE0 EDITWRGRGREGLAPQRKTTNPLDLAVMRLAALEQNVERRYLREPLWPTHEVVLEKALLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDITWRGRGREGLAPQRKTTNPLDLAVMRLAALEQNVERRYLREPLWPTHEVVLEKALLS
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE0 TPNGAPEGTTTEISYEITPRIRVWRQTLERCRSAAQVCLCLGQLERSIAWEKSVNKVTCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPNGAPEGTTTEISYEITPRIRVWRQTLERCRSAAQVCLCLGQLERSIAWEKSVNKVTCL
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE0 VCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQVEGEFTQKPGFPK
:::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
XP_011 VCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQ-VEGEFTQKPGFPK
1690 1700 1710 1720 1730
1750 1760 1770 1780 1790 1800
pF1KE0 RGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMRNHHSDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMRNHHSDLT
1740 1750 1760 1770 1780 1790
1810 1820 1830 1840 1850 1860
pF1KE0 FCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAA
1800 1810 1820 1830 1840 1850
1870 1880 1890 1900
pF1KE0 DALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQANL
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 DALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQANL
1860 1870 1880 1890 1900
>>XP_011536103 (OMIM: 605682) PREDICTED: bromodomain adj (1912 aa)
initn: 10939 init1: 10939 opt: 12827 Z-score: 5554.8 bits: 1041.2 E(85289): 0
Smith-Waterman score: 12827; 99.6% identity (99.6% similar) in 1912 aa overlap (1-1905:1-1912)
10 20 30 40 50 60
pF1KE0 MEMEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEMEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLST
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 YPLNGILGGSRQPSSPSHNTNLRAGSQEFWANGTQSPMGLNFDSQELYDSFPDQNFEVMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPLNGILGGSRQPSSPSHNTNLRAGSQEFWANGTQSPMGLNFDSQELYDSFPDQNFEVMP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 NGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 EEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDPSHLPDQLEDTPILSEDSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDPSHLPDQLEDTPILSEDSLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 PFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNNATAFSLLADDSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNNATAFSLLADDSQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 STSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTIQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 SLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEGLTASGSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEGLTASGSGD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 VMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 VVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 AKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQETLNEEDKAKIAKSKKKMRQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQETLNEEDKAKIAKSKKKMRQK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 VQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 KMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 VPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGVLQEGLLCQGDSLGEVQDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGVLQEGLLCQGDSLGEVQDLL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 VRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEILRCFLMAYGVEPALCDRLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEILRCFLMAYGVEPALCDRLRT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 QPFQAQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSSYRKNKWIVEGRLRRLKTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPFQAQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSSYRKNKWIVEGRLRRLKTVL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE0 AKRTGRSEVEMEGPEECLGRRRSSRIMEETSGMEEEEEEESIAAVPGRRGRRDGEVDATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKRTGRSEVEMEGPEECLGRRRSSRIMEETSGMEEEEEEESIAAVPGRRGRRDGEVDATA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE0 SSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRYRRRYWVLPYLAGIFVEGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRYRRRYWVLPYLAGIFVEGTE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE0 GNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTTASSPARARGRPRKTKPGSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTTASSPARARGRPRKTKPGSM
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE0 QPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQLQSHKGFLEQEGSPLSLGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQLQSHKGFLEQEGSPLSLGQS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE0 QHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPPEEPEPDEAESSPDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPPEEPEPDEAESSPDPQ
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE0 ALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLA
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE0 GLAPKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVPPEMCSGWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLAPKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVPPEMCSGWW
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE0 WIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCLRPSADPIFEPRQLPAFQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCLRPSADPIFEPRQLPAFQEG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE0 IMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCPSPDSTREDLAYCEHLSDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCPSPDSTREDLAYCEHLSDSQ
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE0 EDITWRGRGREGLAPQRKTTNPLDLAVMRLAALEQNVERRYLREPLWPTHEVVLEKALLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDITWRGRGREGLAPQRKTTNPLDLAVMRLAALEQNVERRYLREPLWPTHEVVLEKALLS
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670
pF1KE0 TPNGAPEGTTTEIS-------YEITPRIRVWRQTLERCRSAAQVCLCLGQLERSIAWEKS
:::::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_011 TPNGAPEGTTTEISPLSPSRSYEITPRIRVWRQTLERCRSAAQVCLCLGQLERSIAWEKS
1630 1640 1650 1660 1670 1680
1680 1690 1700 1710 1720 1730
pF1KE0 VNKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQVEGEFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQVEGEFT
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780 1790
pF1KE0 QKPGFPKRGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKPGFPKRGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMR
1750 1760 1770 1780 1790 1800
1800 1810 1820 1830 1840 1850
pF1KE0 NHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYT
1810 1820 1830 1840 1850 1860
1860 1870 1880 1890 1900
pF1KE0 SSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQANL
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQANL
1870 1880 1890 1900 1910
>>XP_011536102 (OMIM: 605682) PREDICTED: bromodomain adj (1931 aa)
initn: 10932 init1: 10932 opt: 12820 Z-score: 5551.7 bits: 1040.6 E(85289): 0
Smith-Waterman score: 12820; 99.6% identity (99.6% similar) in 1911 aa overlap (2-1905:21-1931)
10 20 30 40
pF1KE0 MEMEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMN
::::::::::::::::::::::::::::::::::::::::
XP_011 MEVACILHTRGGVQKTGERREMEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMN
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 FPQQGKSLNGDVNVNGLSTVSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPQQGKSLNGDVNVNGLSTVSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSA
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 NPGSNLKDPPLLSQFSGGQYPLNGILGGSRQPSSPSHNTNLRAGSQEFWANGTQSPMGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPGSNLKDPPLLSQFSGGQYPLNGILGGSRQPSSPSHNTNLRAGSQEFWANGTQSPMGLN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 FDSQELYDSFPDQNFEVMPNGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDSQELYDSFPDQNFEVMPNGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEK
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE0 EMTSVVAENGTGLVGSLELEEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EMTSVVAENGTGLVGSLELEEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDP
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE0 SHLPDQLEDTPILSEDSLEPFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHLPDQLEDTPILSEDSLEPFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALD
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE0 CPSLNNATAFSLLADDSQTSTSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPSLNNATAFSLLADDSQTSTSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQS
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE0 SDFPPSLTQPAPDQSSTIQLHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDFPPSLTQPAPDQSSTIQLHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVV
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE0 SPAVFSVVSPASSAVLPAVSLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPAVFSVVSPASSAVLPAVSLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLET
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE0 TADVEEITGEGLTASGSGDVMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TADVEEITGEGLTASGSGDVMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYG
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE0 PCGKRMKQFPEVIKYLSRNVVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCGKRMKQFPEVIKYLSRNVVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEI
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE0 PSRIQAITGKRGRPRNTEKAKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSRIQAITGKRGRPRNTEKAKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQET
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE0 LNEEDKAKIAKSKKKMRQKVQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNEEDKAKIAKSKKKMRQKVQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKG
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE0 KTKQEKLKEKVKREKKEKVKMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTKQEKLKEKVKREKKEKVKMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMK
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE0 KPTEDMCLTDHQPLPDFSRVPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPTEDMCLTDHQPLPDFSRVPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGV
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE0 LQEGLLCQGDSLGEVQDLLVRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQEGLLCQGDSLGEVQDLLVRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEIL
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE0 RCFLMAYGVEPALCDRLRTQPFQAQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCFLMAYGVEPALCDRLRTQPFQAQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSS
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE0 YRKNKWIVEGRLRRLKTVLAKRTGRSEVEMEGPEECLGRRRSSRIMEETSGMEEEEEEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRKNKWIVEGRLRRLKTVLAKRTGRSEVEMEGPEECLGRRRSSRIMEETSGMEEEEEEES
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KE0 IAAVPGRRGRRDGEVDATASSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAAVPGRRGRRDGEVDATASSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRY
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KE0 RRRYWVLPYLAGIFVEGTEGNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRRYWVLPYLAGIFVEGTEGNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTT
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KE0 ASSPARARGRPRKTKPGSMQPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASSPARARGRPRKTKPGSMQPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQL
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KE0 QSHKGFLEQEGSPLSLGQSQHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSHKGFLEQEGSPLSLGQSQHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAP
1270 1280 1290 1300 1310 1320
1310 1320 1330 1340 1350 1360
pF1KE0 SQPPEEPEPDEAESSPDPQALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQPPEEPEPDEAESSPDPQALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMN
1330 1340 1350 1360 1370 1380
1370 1380 1390 1400 1410 1420
pF1KE0 RPSAANPCSPVQFSSTPLAGLAPKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPSAANPCSPVQFSSTPLAGLAPKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQR
1390 1400 1410 1420 1430 1440
1430 1440 1450 1460 1470 1480
pF1KE0 YLTQLTAQPVPPEMCSGWWWIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLTQLTAQPVPPEMCSGWWWIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCL
1450 1460 1470 1480 1490 1500
1490 1500 1510 1520 1530 1540
pF1KE0 RPSADPIFEPRQLPAFQEGIMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPSADPIFEPRQLPAFQEGIMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCP
1510 1520 1530 1540 1550 1560
1550 1560 1570 1580 1590 1600
pF1KE0 SPDSTREDLAYCEHLSDSQEDITWRGRGREGLAPQRKTTNPLDLAVMRLAALEQNVERRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPDSTREDLAYCEHLSDSQEDITWRGRGREGLAPQRKTTNPLDLAVMRLAALEQNVERRY
1570 1580 1590 1600 1610 1620
1610 1620 1630 1640 1650
pF1KE0 LREPLWPTHEVVLEKALLSTPNGAPEGTTTEIS-------YEITPRIRVWRQTLERCRSA
::::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_011 LREPLWPTHEVVLEKALLSTPNGAPEGTTTEISPLSPSRSYEITPRIRVWRQTLERCRSA
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
pF1KE0 AQVCLCLGQLERSIAWEKSVNKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQVCLCLGQLERSIAWEKSVNKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVP
1690 1700 1710 1720 1730 1740
1720 1730 1740 1750 1760 1770
pF1KE0 EGDWFCTVCLAQQVEGEFTQKPGFPKRGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGDWFCTVCLAQQVEGEFTQKPGFPKRGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAG
1750 1760 1770 1780 1790 1800
1780 1790 1800 1810 1820 1830
pF1KE0 PRYSEEGLSPSKRRRLSMRNHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRYSEEGLSPSKRRRLSMRNHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRII
1810 1820 1830 1840 1850 1860
1840 1850 1860 1870 1880 1890
pF1KE0 KNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRW
1870 1880 1890 1900 1910 1920
1900
pF1KE0 EEFYQGKQANL
:::::::::::
XP_011 EEFYQGKQANL
1930
>>XP_011536105 (OMIM: 605682) PREDICTED: bromodomain adj (1910 aa)
initn: 10926 init1: 10926 opt: 12814 Z-score: 5549.2 bits: 1040.2 E(85289): 0
Smith-Waterman score: 12814; 99.6% identity (99.6% similar) in 1910 aa overlap (3-1905:1-1910)
10 20 30 40 50 60
pF1KE0 MEMEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLST
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 VSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 YPLNGILGGSRQPSSPSHNTNLRAGSQEFWANGTQSPMGLNFDSQELYDSFPDQNFEVMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPLNGILGGSRQPSSPSHNTNLRAGSQEFWANGTQSPMGLNFDSQELYDSFPDQNFEVMP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 NGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLEL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 EEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDPSHLPDQLEDTPILSEDSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDPSHLPDQLEDTPILSEDSLE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE0 PFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNNATAFSLLADDSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNNATAFSLLADDSQT
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE0 STSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTIQ
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE0 LHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAV
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE0 SLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEGLTASGSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEGLTASGSGD
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE0 VMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRN
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE0 VVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEK
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE0 AKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQETLNEEDKAKIAKSKKKMRQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQETLNEEDKAKIAKSKKKMRQK
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE0 VQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKV
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE0 KMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSR
780 790 800 810 820 830
850 860 870 880 890 900
pF1KE0 VPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGVLQEGLLCQGDSLGEVQDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGVLQEGLLCQGDSLGEVQDLL
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE0 VRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEILRCFLMAYGVEPALCDRLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEILRCFLMAYGVEPALCDRLRT
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE0 QPFQAQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSSYRKNKWIVEGRLRRLKTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPFQAQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSSYRKNKWIVEGRLRRLKTVL
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KE0 AKRTGRSEVEMEGPEECLGRRRSSRIMEETSGMEEEEEEESIAAVPGRRGRRDGEVDATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKRTGRSEVEMEGPEECLGRRRSSRIMEETSGMEEEEEEESIAAVPGRRGRRDGEVDATA
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KE0 SSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRYRRRYWVLPYLAGIFVEGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRYRRRYWVLPYLAGIFVEGTE
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KE0 GNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTTASSPARARGRPRKTKPGSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTTASSPARARGRPRKTKPGSM
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KE0 QPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQLQSHKGFLEQEGSPLSLGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQLQSHKGFLEQEGSPLSLGQS
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KE0 QHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPPEEPEPDEAESSPDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPPEEPEPDEAESSPDPQ
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KE0 ALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLA
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KE0 GLAPKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVPPEMCSGWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLAPKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVPPEMCSGWW
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KE0 WIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCLRPSADPIFEPRQLPAFQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCLRPSADPIFEPRQLPAFQEG
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KE0 IMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCPSPDSTREDLAYCEHLSDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCPSPDSTREDLAYCEHLSDSQ
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KE0 EDITWRGRGREGLAPQRKTTNPLDLAVMRLAALEQNVERRYLREPLWPTHEVVLEKALLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDITWRGRGREGLAPQRKTTNPLDLAVMRLAALEQNVERRYLREPLWPTHEVVLEKALLS
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670
pF1KE0 TPNGAPEGTTTEIS-------YEITPRIRVWRQTLERCRSAAQVCLCLGQLERSIAWEKS
:::::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_011 TPNGAPEGTTTEISPLSPSRSYEITPRIRVWRQTLERCRSAAQVCLCLGQLERSIAWEKS
1620 1630 1640 1650 1660 1670
1680 1690 1700 1710 1720 1730
pF1KE0 VNKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQVEGEFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQVEGEFT
1680 1690 1700 1710 1720 1730
1740 1750 1760 1770 1780 1790
pF1KE0 QKPGFPKRGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKPGFPKRGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMR
1740 1750 1760 1770 1780 1790
1800 1810 1820 1830 1840 1850
pF1KE0 NHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYT
1800 1810 1820 1830 1840 1850
1860 1870 1880 1890 1900
pF1KE0 SSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQANL
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQANL
1860 1870 1880 1890 1900 1910
>>XP_011536107 (OMIM: 605682) PREDICTED: bromodomain adj (1910 aa)
initn: 10926 init1: 10926 opt: 12814 Z-score: 5549.2 bits: 1040.2 E(85289): 0
Smith-Waterman score: 12814; 99.6% identity (99.6% similar) in 1910 aa overlap (3-1905:1-1910)
10 20 30 40 50 60
pF1KE0 MEMEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLST
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 VSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 YPLNGILGGSRQPSSPSHNTNLRAGSQEFWANGTQSPMGLNFDSQELYDSFPDQNFEVMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPLNGILGGSRQPSSPSHNTNLRAGSQEFWANGTQSPMGLNFDSQELYDSFPDQNFEVMP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 NGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLEL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 EEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDPSHLPDQLEDTPILSEDSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDPSHLPDQLEDTPILSEDSLE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE0 PFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNNATAFSLLADDSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNNATAFSLLADDSQT
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE0 STSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTIQ
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE0 LHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAV
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE0 SLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEGLTASGSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEGLTASGSGD
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE0 VMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRN
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE0 VVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEK
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE0 AKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQETLNEEDKAKIAKSKKKMRQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQETLNEEDKAKIAKSKKKMRQK
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE0 VQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKV
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE0 KMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSR
780 790 800 810 820 830
850 860 870 880 890 900
pF1KE0 VPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGVLQEGLLCQGDSLGEVQDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGVLQEGLLCQGDSLGEVQDLL
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE0 VRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEILRCFLMAYGVEPALCDRLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEILRCFLMAYGVEPALCDRLRT
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE0 QPFQAQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSSYRKNKWIVEGRLRRLKTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPFQAQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSSYRKNKWIVEGRLRRLKTVL
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KE0 AKRTGRSEVEMEGPEECLGRRRSSRIMEETSGMEEEEEEESIAAVPGRRGRRDGEVDATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKRTGRSEVEMEGPEECLGRRRSSRIMEETSGMEEEEEEESIAAVPGRRGRRDGEVDATA
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KE0 SSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRYRRRYWVLPYLAGIFVEGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRYRRRYWVLPYLAGIFVEGTE
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KE0 GNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTTASSPARARGRPRKTKPGSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTTASSPARARGRPRKTKPGSM
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KE0 QPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQLQSHKGFLEQEGSPLSLGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQLQSHKGFLEQEGSPLSLGQS
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KE0 QHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPPEEPEPDEAESSPDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPPEEPEPDEAESSPDPQ
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KE0 ALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLA
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KE0 GLAPKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVPPEMCSGWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLAPKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVPPEMCSGWW
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KE0 WIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCLRPSADPIFEPRQLPAFQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCLRPSADPIFEPRQLPAFQEG
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KE0 IMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCPSPDSTREDLAYCEHLSDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCPSPDSTREDLAYCEHLSDSQ
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KE0 EDITWRGRGREGLAPQRKTTNPLDLAVMRLAALEQNVERRYLREPLWPTHEVVLEKALLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDITWRGRGREGLAPQRKTTNPLDLAVMRLAALEQNVERRYLREPLWPTHEVVLEKALLS
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670
pF1KE0 TPNGAPEGTTTEIS-------YEITPRIRVWRQTLERCRSAAQVCLCLGQLERSIAWEKS
:::::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_011 TPNGAPEGTTTEISPLSPSRSYEITPRIRVWRQTLERCRSAAQVCLCLGQLERSIAWEKS
1620 1630 1640 1650 1660 1670
1680 1690 1700 1710 1720 1730
pF1KE0 VNKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQVEGEFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQVEGEFT
1680 1690 1700 1710 1720 1730
1740 1750 1760 1770 1780 1790
pF1KE0 QKPGFPKRGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKPGFPKRGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMR
1740 1750 1760 1770 1780 1790
1800 1810 1820 1830 1840 1850
pF1KE0 NHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYT
1800 1810 1820 1830 1840 1850
1860 1870 1880 1890 1900
pF1KE0 SSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQANL
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQANL
1860 1870 1880 1890 1900 1910
>>XP_011536106 (OMIM: 605682) PREDICTED: bromodomain adj (1910 aa)
initn: 10926 init1: 10926 opt: 12814 Z-score: 5549.2 bits: 1040.2 E(85289): 0
Smith-Waterman score: 12814; 99.6% identity (99.6% similar) in 1910 aa overlap (3-1905:1-1910)
10 20 30 40 50 60
pF1KE0 MEMEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLST
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 VSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 YPLNGILGGSRQPSSPSHNTNLRAGSQEFWANGTQSPMGLNFDSQELYDSFPDQNFEVMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPLNGILGGSRQPSSPSHNTNLRAGSQEFWANGTQSPMGLNFDSQELYDSFPDQNFEVMP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 NGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLEL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 EEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDPSHLPDQLEDTPILSEDSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDPSHLPDQLEDTPILSEDSLE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE0 PFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNNATAFSLLADDSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNNATAFSLLADDSQT
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE0 STSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTIQ
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE0 LHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAV
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE0 SLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEGLTASGSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEGLTASGSGD
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE0 VMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRN
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE0 VVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEK
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE0 AKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQETLNEEDKAKIAKSKKKMRQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQETLNEEDKAKIAKSKKKMRQK
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE0 VQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKV
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE0 KMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSR
780 790 800 810 820 830
850 860 870 880 890 900
pF1KE0 VPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGVLQEGLLCQGDSLGEVQDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGVLQEGLLCQGDSLGEVQDLL
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE0 VRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEILRCFLMAYGVEPALCDRLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEILRCFLMAYGVEPALCDRLRT
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE0 QPFQAQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSSYRKNKWIVEGRLRRLKTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPFQAQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSSYRKNKWIVEGRLRRLKTVL
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KE0 AKRTGRSEVEMEGPEECLGRRRSSRIMEETSGMEEEEEEESIAAVPGRRGRRDGEVDATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKRTGRSEVEMEGPEECLGRRRSSRIMEETSGMEEEEEEESIAAVPGRRGRRDGEVDATA
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KE0 SSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRYRRRYWVLPYLAGIFVEGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRYRRRYWVLPYLAGIFVEGTE
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KE0 GNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTTASSPARARGRPRKTKPGSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTTASSPARARGRPRKTKPGSM
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KE0 QPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQLQSHKGFLEQEGSPLSLGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQLQSHKGFLEQEGSPLSLGQS
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KE0 QHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPPEEPEPDEAESSPDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPPEEPEPDEAESSPDPQ
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KE0 ALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLA
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KE0 GLAPKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVPPEMCSGWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLAPKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVPPEMCSGWW
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KE0 WIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCLRPSADPIFEPRQLPAFQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCLRPSADPIFEPRQLPAFQEG
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KE0 IMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCPSPDSTREDLAYCEHLSDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCPSPDSTREDLAYCEHLSDSQ
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KE0 EDITWRGRGREGLAPQRKTTNPLDLAVMRLAALEQNVERRYLREPLWPTHEVVLEKALLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDITWRGRGREGLAPQRKTTNPLDLAVMRLAALEQNVERRYLREPLWPTHEVVLEKALLS
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670
pF1KE0 TPNGAPEGTTTEIS-------YEITPRIRVWRQTLERCRSAAQVCLCLGQLERSIAWEKS
:::::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_011 TPNGAPEGTTTEISPLSPSRSYEITPRIRVWRQTLERCRSAAQVCLCLGQLERSIAWEKS
1620 1630 1640 1650 1660 1670
1680 1690 1700 1710 1720 1730
pF1KE0 VNKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQVEGEFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQVEGEFT
1680 1690 1700 1710 1720 1730
1740 1750 1760 1770 1780 1790
pF1KE0 QKPGFPKRGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKPGFPKRGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMR
1740 1750 1760 1770 1780 1790
1800 1810 1820 1830 1840 1850
pF1KE0 NHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYT
1800 1810 1820 1830 1840 1850
1860 1870 1880 1890 1900
pF1KE0 SSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQANL
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQANL
1860 1870 1880 1890 1900 1910
>>XP_016874230 (OMIM: 605682) PREDICTED: bromodomain adj (1910 aa)
initn: 10926 init1: 10926 opt: 12814 Z-score: 5549.2 bits: 1040.2 E(85289): 0
Smith-Waterman score: 12814; 99.6% identity (99.6% similar) in 1910 aa overlap (3-1905:1-1910)
10 20 30 40 50 60
pF1KE0 MEMEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLST
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 VSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 YPLNGILGGSRQPSSPSHNTNLRAGSQEFWANGTQSPMGLNFDSQELYDSFPDQNFEVMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPLNGILGGSRQPSSPSHNTNLRAGSQEFWANGTQSPMGLNFDSQELYDSFPDQNFEVMP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 NGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLEL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 EEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDPSHLPDQLEDTPILSEDSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDPSHLPDQLEDTPILSEDSLE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE0 PFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNNATAFSLLADDSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNNATAFSLLADDSQT
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE0 STSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTIQ
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE0 LHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAV
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE0 SLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEGLTASGSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEGLTASGSGD
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE0 VMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRN
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE0 VVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEK
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE0 AKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQETLNEEDKAKIAKSKKKMRQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQETLNEEDKAKIAKSKKKMRQK
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE0 VQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKV
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE0 KMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSR
780 790 800 810 820 830
850 860 870 880 890 900
pF1KE0 VPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGVLQEGLLCQGDSLGEVQDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGVLQEGLLCQGDSLGEVQDLL
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE0 VRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEILRCFLMAYGVEPALCDRLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEILRCFLMAYGVEPALCDRLRT
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE0 QPFQAQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSSYRKNKWIVEGRLRRLKTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPFQAQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSSYRKNKWIVEGRLRRLKTVL
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KE0 AKRTGRSEVEMEGPEECLGRRRSSRIMEETSGMEEEEEEESIAAVPGRRGRRDGEVDATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKRTGRSEVEMEGPEECLGRRRSSRIMEETSGMEEEEEEESIAAVPGRRGRRDGEVDATA
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KE0 SSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRYRRRYWVLPYLAGIFVEGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRYRRRYWVLPYLAGIFVEGTE
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KE0 GNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTTASSPARARGRPRKTKPGSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTTASSPARARGRPRKTKPGSM
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KE0 QPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQLQSHKGFLEQEGSPLSLGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQLQSHKGFLEQEGSPLSLGQS
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KE0 QHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPPEEPEPDEAESSPDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPPEEPEPDEAESSPDPQ
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KE0 ALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLA
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KE0 GLAPKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVPPEMCSGWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLAPKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVPPEMCSGWW
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KE0 WIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCLRPSADPIFEPRQLPAFQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCLRPSADPIFEPRQLPAFQEG
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KE0 IMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCPSPDSTREDLAYCEHLSDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCPSPDSTREDLAYCEHLSDSQ
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KE0 EDITWRGRGREGLAPQRKTTNPLDLAVMRLAALEQNVERRYLREPLWPTHEVVLEKALLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDITWRGRGREGLAPQRKTTNPLDLAVMRLAALEQNVERRYLREPLWPTHEVVLEKALLS
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670
pF1KE0 TPNGAPEGTTTEIS-------YEITPRIRVWRQTLERCRSAAQVCLCLGQLERSIAWEKS
:::::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_016 TPNGAPEGTTTEISPLSPSRSYEITPRIRVWRQTLERCRSAAQVCLCLGQLERSIAWEKS
1620 1630 1640 1650 1660 1670
1680 1690 1700 1710 1720 1730
pF1KE0 VNKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQVEGEFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQVEGEFT
1680 1690 1700 1710 1720 1730
1740 1750 1760 1770 1780 1790
pF1KE0 QKPGFPKRGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKPGFPKRGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMR
1740 1750 1760 1770 1780 1790
1800 1810 1820 1830 1840 1850
pF1KE0 NHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYT
1800 1810 1820 1830 1840 1850
1860 1870 1880 1890 1900
pF1KE0 SSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQANL
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQANL
1860 1870 1880 1890 1900 1910
>>XP_016874229 (OMIM: 605682) PREDICTED: bromodomain adj (1910 aa)
initn: 10926 init1: 10926 opt: 12814 Z-score: 5549.2 bits: 1040.2 E(85289): 0
Smith-Waterman score: 12814; 99.6% identity (99.6% similar) in 1910 aa overlap (3-1905:1-1910)
10 20 30 40 50 60
pF1KE0 MEMEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLST
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 VSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSHTTTSGILNSAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 YPLNGILGGSRQPSSPSHNTNLRAGSQEFWANGTQSPMGLNFDSQELYDSFPDQNFEVMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPLNGILGGSRQPSSPSHNTNLRAGSQEFWANGTQSPMGLNFDSQELYDSFPDQNFEVMP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 NGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGPPSFFTSPQTSPMLGSSIQTFAPSQEVGSGIHPDEAAEKEMTSVVAENGTGLVGSLEL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 EEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDPSHLPDQLEDTPILSEDSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCLDDPSHLPDQLEDTPILSEDSLE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE0 PFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNNATAFSLLADDSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNNATAFSLLADDSQT
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE0 STSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTIQ
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE0 LHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAV
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE0 SLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEGLTASGSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEGLTASGSGD
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE0 VMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRN
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE0 VVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEK
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE0 AKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQETLNEEDKAKIAKSKKKMRQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQETLNEEDKAKIAKSKKKMRQK
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE0 VQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKV
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE0 KMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSR
780 790 800 810 820 830
850 860 870 880 890 900
pF1KE0 VPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGVLQEGLLCQGDSLGEVQDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGVLQEGLLCQGDSLGEVQDLL
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE0 VRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEILRCFLMAYGVEPALCDRLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEILRCFLMAYGVEPALCDRLRT
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE0 QPFQAQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSSYRKNKWIVEGRLRRLKTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPFQAQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSSYRKNKWIVEGRLRRLKTVL
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KE0 AKRTGRSEVEMEGPEECLGRRRSSRIMEETSGMEEEEEEESIAAVPGRRGRRDGEVDATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKRTGRSEVEMEGPEECLGRRRSSRIMEETSGMEEEEEEESIAAVPGRRGRRDGEVDATA
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KE0 SSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRYRRRYWVLPYLAGIFVEGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRYRRRYWVLPYLAGIFVEGTE
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KE0 GNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTTASSPARARGRPRKTKPGSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTTASSPARARGRPRKTKPGSM
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KE0 QPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQLQSHKGFLEQEGSPLSLGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQLQSHKGFLEQEGSPLSLGQS
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KE0 QHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPPEEPEPDEAESSPDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPPEEPEPDEAESSPDPQ
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KE0 ALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLA
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KE0 GLAPKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVPPEMCSGWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLAPKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVPPEMCSGWW
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KE0 WIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCLRPSADPIFEPRQLPAFQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCLRPSADPIFEPRQLPAFQEG
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KE0 IMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCPSPDSTREDLAYCEHLSDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCPSPDSTREDLAYCEHLSDSQ
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KE0 EDITWRGRGREGLAPQRKTTNPLDLAVMRLAALEQNVERRYLREPLWPTHEVVLEKALLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDITWRGRGREGLAPQRKTTNPLDLAVMRLAALEQNVERRYLREPLWPTHEVVLEKALLS
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670
pF1KE0 TPNGAPEGTTTEIS-------YEITPRIRVWRQTLERCRSAAQVCLCLGQLERSIAWEKS
:::::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_016 TPNGAPEGTTTEISPLSPSRSYEITPRIRVWRQTLERCRSAAQVCLCLGQLERSIAWEKS
1620 1630 1640 1650 1660 1670
1680 1690 1700 1710 1720 1730
pF1KE0 VNKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQVEGEFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQVEGEFT
1680 1690 1700 1710 1720 1730
1740 1750 1760 1770 1780 1790
pF1KE0 QKPGFPKRGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKPGFPKRGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMR
1740 1750 1760 1770 1780 1790
1800 1810 1820 1830 1840 1850
pF1KE0 NHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYT
1800 1810 1820 1830 1840 1850
1860 1870 1880 1890 1900
pF1KE0 SSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQANL
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQANL
1860 1870 1880 1890 1900 1910
1905 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 03:36:01 2016 done: Fri Nov 4 03:36:04 2016
Total Scan time: 21.090 Total Display time: 1.270
Function used was FASTA [36.3.4 Apr, 2011]