Result of FASTA (omim) for
pFN21AB9904
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9904, 589 aa
1>>>pF1KB9904 589 - 589 aa - 589 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.2206+/-0.00041; mu= 5.0959+/- 0.026
mean_var=364.1082+/-73.469, 0's: 0 Z-trim(122.6): 42 B-trim: 93 in 1/59
Lambda= 0.067214
statistics sampled from 40928 (40975) to 40928 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.48), width: 16
Scan time: 9.140
The best scores are: opt bits E(85289)
NP_001524 (OMIM: 603083) heterogeneous nuclear rib ( 589) 4115 413.1 1.3e-114
XP_011525189 (OMIM: 603083) PREDICTED: heterogeneo ( 532) 3496 353.0 1.4e-96
XP_011525188 (OMIM: 603083) PREDICTED: heterogeneo ( 518) 3491 352.5 1.9e-96
XP_011525191 (OMIM: 603083) PREDICTED: heterogeneo ( 456) 3200 324.3 5.6e-88
NP_001005335 (OMIM: 603083) heterogeneous nuclear ( 456) 3200 324.3 5.6e-88
XP_011525190 (OMIM: 603083) PREDICTED: heterogeneo ( 528) 2310 238.0 5.9e-62
NP_001136122 (OMIM: 611208) heterogeneous nuclear ( 537) 1025 113.4 1.9e-24
NP_612403 (OMIM: 611208) heterogeneous nuclear rib ( 542) 1025 113.4 1.9e-24
XP_011531468 (OMIM: 611208) PREDICTED: heterogeneo ( 570) 1025 113.5 2e-24
XP_005264697 (OMIM: 611208) PREDICTED: heterogeneo ( 590) 1025 113.5 2e-24
XP_005264696 (OMIM: 611208) PREDICTED: heterogeneo ( 595) 1025 113.5 2e-24
XP_011531467 (OMIM: 611208) PREDICTED: heterogeneo ( 571) 970 108.1 8e-23
>>NP_001524 (OMIM: 603083) heterogeneous nuclear ribonuc (589 aa)
initn: 4115 init1: 4115 opt: 4115 Z-score: 2178.7 bits: 413.1 E(85289): 1.3e-114
Smith-Waterman score: 4115; 100.0% identity (100.0% similar) in 589 aa overlap (1-589:1-589)
10 20 30 40 50 60
pF1KB9 MSRRLLPRAEKRRRRLEQRQQPDEQRRRSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSRRLLPRAEKRRRRLEQRQQPDEQRRRSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LKTDNAGDQHGGGGGGGGGAGAAGGGGGGENYDDPHKTPASPVVHIRGLIDGVVEADLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKTDNAGDQHGGGGGGGGGAGAAGGGGGGENYDDPHKTPASPVVHIRGLIDGVVEADLVE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 ALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKIS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 RPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 VQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSNP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 NKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 PQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 AAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSES
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 RNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGKSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGKSE
490 500 510 520 530 540
550 560 570 580
pF1KB9 RSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS
550 560 570 580
>>XP_011525189 (OMIM: 603083) PREDICTED: heterogeneous n (532 aa)
initn: 3496 init1: 3496 opt: 3496 Z-score: 1854.8 bits: 353.0 E(85289): 1.4e-96
Smith-Waterman score: 3581; 90.3% identity (90.3% similar) in 589 aa overlap (1-589:1-532)
10 20 30 40 50 60
pF1KB9 MSRRLLPRAEKRRRRLEQRQQPDEQRRRSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKR
::::::::::::::::::::::::::::::::
XP_011 MSRRLLPRAEKRRRRLEQRQQPDEQRRRSGAM----------------------------
10 20 30
70 80 90 100 110 120
pF1KB9 LKTDNAGDQHGGGGGGGGGAGAAGGGGGGENYDDPHKTPASPVVHIRGLIDGVVEADLVE
:::::::::::::::::::::::::::::::
XP_011 -----------------------------ENYDDPHKTPASPVVHIRGLIDGVVEADLVE
40 50 60
130 140 150 160 170 180
pF1KB9 ALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKIS
70 80 90 100 110 120
190 200 210 220 230 240
pF1KB9 RPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDS
130 140 150 160 170 180
250 260 270 280 290 300
pF1KB9 VQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSNP
190 200 210 220 230 240
310 320 330 340 350 360
pF1KB9 NKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYG
250 260 270 280 290 300
370 380 390 400 410 420
pF1KB9 PQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPG
310 320 330 340 350 360
430 440 450 460 470 480
pF1KB9 AAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSES
370 380 390 400 410 420
490 500 510 520 530 540
pF1KB9 RNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGKSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGKSE
430 440 450 460 470 480
550 560 570 580
pF1KB9 RSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS
490 500 510 520 530
>>XP_011525188 (OMIM: 603083) PREDICTED: heterogeneous n (518 aa)
initn: 3491 init1: 3491 opt: 3491 Z-score: 1852.4 bits: 352.5 E(85289): 1.9e-96
Smith-Waterman score: 3491; 100.0% identity (100.0% similar) in 500 aa overlap (90-589:19-518)
60 70 80 90 100 110
pF1KB9 RLKTDNAGDQHGGGGGGGGGAGAAGGGGGGENYDDPHKTPASPVVHIRGLIDGVVEADLV
::::::::::::::::::::::::::::::
XP_011 MRRRSVPARPRGRLGERLENYDDPHKTPASPVVHIRGLIDGVVEADLV
10 20 30 40
120 130 140 150 160 170
pF1KB9 EALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKI
50 60 70 80 90 100
180 190 200 210 220 230
pF1KB9 SRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFD
110 120 130 140 150 160
240 250 260 270 280 290
pF1KB9 SVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSN
170 180 190 200 210 220
300 310 320 330 340 350
pF1KB9 PNKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRY
230 240 250 260 270 280
360 370 380 390 400 410
pF1KB9 GPQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKP
290 300 310 320 330 340
420 430 440 450 460 470
pF1KB9 GAAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSE
350 360 370 380 390 400
480 490 500 510 520 530
pF1KB9 SRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGKS
410 420 430 440 450 460
540 550 560 570 580
pF1KB9 ERSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS
470 480 490 500 510
>>XP_011525191 (OMIM: 603083) PREDICTED: heterogeneous n (456 aa)
initn: 3200 init1: 3200 opt: 3200 Z-score: 1700.5 bits: 324.3 E(85289): 5.6e-88
Smith-Waterman score: 3200; 100.0% identity (100.0% similar) in 456 aa overlap (134-589:1-456)
110 120 130 140 150 160
pF1KB9 VHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIY
::::::::::::::::::::::::::::::
XP_011 MPKKRQALVEFEDVLGACNAVNYAADNQIY
10 20 30
170 180 190 200 210 220
pF1KB9 IAGHPAFVNYSTSQKISRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAGHPAFVNYSTSQKISRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQR
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB9 IVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTW
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB9 DYTNPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYTNPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGR
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB9 RMGPPVGGHRRGPSRYGPQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSKMNCDRVFNVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RMGPPVGGHRRGPSRYGPQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSKMNCDRVFNVF
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB9 CLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPAIMPGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPAIMPGQ
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB9 SYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDE
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB9 LGVKRPSSVKVFSGKSERSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYTLKLCFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGVKRPSSVKVFSGKSERSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYTLKLCFS
400 410 420 430 440 450
pF1KB9 TAQHAS
::::::
XP_011 TAQHAS
>>NP_001005335 (OMIM: 603083) heterogeneous nuclear ribo (456 aa)
initn: 3200 init1: 3200 opt: 3200 Z-score: 1700.5 bits: 324.3 E(85289): 5.6e-88
Smith-Waterman score: 3200; 100.0% identity (100.0% similar) in 456 aa overlap (134-589:1-456)
110 120 130 140 150 160
pF1KB9 VHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIY
::::::::::::::::::::::::::::::
NP_001 MPKKRQALVEFEDVLGACNAVNYAADNQIY
10 20 30
170 180 190 200 210 220
pF1KB9 IAGHPAFVNYSTSQKISRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAGHPAFVNYSTSQKISRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQR
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB9 IVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTW
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB9 DYTNPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYTNPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGR
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB9 RMGPPVGGHRRGPSRYGPQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSKMNCDRVFNVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RMGPPVGGHRRGPSRYGPQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSKMNCDRVFNVF
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB9 CLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPAIMPGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPAIMPGQ
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB9 SYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDE
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB9 LGVKRPSSVKVFSGKSERSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYTLKLCFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGVKRPSSVKVFSGKSERSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYTLKLCFS
400 410 420 430 440 450
pF1KB9 TAQHAS
::::::
NP_001 TAQHAS
>>XP_011525190 (OMIM: 603083) PREDICTED: heterogeneous n (528 aa)
initn: 3690 init1: 2305 opt: 2310 Z-score: 1233.3 bits: 238.0 E(85289): 5.9e-62
Smith-Waterman score: 3572; 89.6% identity (89.6% similar) in 589 aa overlap (1-589:1-528)
10 20 30 40 50 60
pF1KB9 MSRRLLPRAEKRRRRLEQRQQPDEQRRRSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSRRLLPRAEKRRRRLEQRQQPDEQRRRSGAMVKMAAAGGGGGGGRYYGGGSEGGRAPKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LKTDNAGDQHGGGGGGGGGAGAAGGGGGGENYDDPHKTPASPVVHIRGLIDGVVEADLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKTDNAGDQHGGGGGGGGGAGAAGGGGGGENYDDPHKTPASPVVHIRGLIDGVVEADLVE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 ALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKIS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 RPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDS
::::::::::::::::::::::::::::
XP_011 RPGDSDDSRSVNSVLLFTILNPIYSITT--------------------------------
190 200
250 260 270 280 290 300
pF1KB9 VQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSNP
:::::::::::::::::::::::::::::::
XP_011 -----------------------------PTRLNVFKNDQDTWDYTNPNLSGQGDPGSNP
210 220 230
310 320 330 340 350 360
pF1KB9 NKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHYEGRRMGPPVGGHRRGPSRYG
240 250 260 270 280 290
370 380 390 400 410 420
pF1KB9 PQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPG
300 310 320 330 340 350
430 440 450 460 470 480
pF1KB9 AAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPAIMPGQSYGLEDGSCSYKDFSES
360 370 380 390 400 410
490 500 510 520 530 540
pF1KB9 RNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGKSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPSSVKVFSGKSE
420 430 440 450 460 470
550 560 570 580
pF1KB9 RSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYTLKLCFSTAQHAS
480 490 500 510 520
>>NP_001136122 (OMIM: 611208) heterogeneous nuclear ribo (537 aa)
initn: 1767 init1: 934 opt: 1025 Z-score: 559.8 bits: 113.4 E(85289): 1.9e-24
Smith-Waterman score: 1884; 57.1% identity (76.7% similar) in 520 aa overlap (71-587:44-536)
50 60 70 80 90 100
pF1KB9 GGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGENYDDPHKTPA
::: ::::: . . .:: . ::. .
NP_001 ESQAKRLKTEEGEIDYSAEEGENRREATPRGGGDGGGGGRSFSQPEAGGSH----HKVSV
20 30 40 50 60
110 120 130 140 150 160
pF1KB9 SPVVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADN
:::::.::: ..::::::::::..:: : ::..:: :::::::::.. .: . :..:::.
NP_001 SPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADE
70 80 90 100 110 120
170 180 190 200 210 220
pF1KB9 QIYIAGHPAFVNYSTSQKISRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGP
.::::. :: :::::..:.:::..:: . :.:::..: ::.: ::.:::::.::: :
NP_001 PVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGK
130 140 150 160 170 180
230 240 250 260 270 280
pF1KB9 VQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQ
:::::::..::.::::::.:: ::.:::.:::::::.::::::::::.::::::..::.
NP_001 VQRIVIFKRNGIQAMVEFESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLNVIRNDN
190 200 210 220 230 240
290 300 310 320 330 340
pF1KB9 DTWDYTNPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHY
:.::::.: : :. : :.. :::: .::.::. . : :: :: :: :
NP_001 DSWDYTKPYL-GRRDRGKG---RQRQA-ILGEHPSSFR--HDGYGSH------GPLLPLP
250 260 270 280 290
350 360 370 380 390
pF1KB9 EGRRMGPPVGGHRRGPSRYGPQYGHPPPPPPPPEY--GPHADSPVLMVYGLDQSKMNCDR
::: :: :. : : : : . .. :.:: :: : ::::.:
NP_001 SRYRMG----------SRDTPELVAYPLPQASSSYMHGGNPSGSVVMVSGLHQLKMNCSR
300 310 320 330 340
400 410 420 430 440 450
pF1KB9 VFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPA
:::.::::::.:::::::. ::.:.:::.: :::.::.::::: .::..:::::::: .
NP_001 VFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHS
350 360 370 380 390 400
460 470 480 490 500 510
pF1KB9 IMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFF
..:.: . ::::. :::::. :.::::.. ::.:: :: :: :::..:.:: ::::.:
NP_001 VVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFT
410 420 430 440 450 460
520 530 540 550 560 570
pF1KB9 EICDELGVKRPSSVKVFSGK-SERSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYT
..:.. : . :::..: : .. ::::::: :.::.:.: :::::.. ::: :::
NP_001 KLCNDHEVLTFIKYKVFDAKPSAKTLSGLLEWECKTDAVEALTALNHYQIRVPNGSNPYT
470 480 490 500 510 520
580
pF1KB9 LKLCFSTAQHAS
:::::::..:
NP_001 LKLCFSTSSHL
530
>>NP_612403 (OMIM: 611208) heterogeneous nuclear ribonuc (542 aa)
initn: 1767 init1: 934 opt: 1025 Z-score: 559.8 bits: 113.4 E(85289): 1.9e-24
Smith-Waterman score: 1884; 57.1% identity (76.7% similar) in 520 aa overlap (71-587:49-541)
50 60 70 80 90 100
pF1KB9 GGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGENYDDPHKTPA
::: ::::: . . .:: . ::. .
NP_612 ESQAKRLKTEEGEIDYSAEEGENRREATPRGGGDGGGGGRSFSQPEAGGSH----HKVSV
20 30 40 50 60 70
110 120 130 140 150 160
pF1KB9 SPVVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADN
:::::.::: ..::::::::::..:: : ::..:: :::::::::.. .: . :..:::.
NP_612 SPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADE
80 90 100 110 120 130
170 180 190 200 210 220
pF1KB9 QIYIAGHPAFVNYSTSQKISRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGP
.::::. :: :::::..:.:::..:: . :.:::..: ::.: ::.:::::.::: :
NP_612 PVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGK
140 150 160 170 180 190
230 240 250 260 270 280
pF1KB9 VQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQ
:::::::..::.::::::.:: ::.:::.:::::::.::::::::::.::::::..::.
NP_612 VQRIVIFKRNGIQAMVEFESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLNVIRNDN
200 210 220 230 240 250
290 300 310 320 330 340
pF1KB9 DTWDYTNPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHY
:.::::.: : :. : :.. :::: .::.::. . : :: :: :: :
NP_612 DSWDYTKPYL-GRRDRGKG---RQRQA-ILGEHPSSFR--HDGYGSH------GPLLPLP
260 270 280 290 300
350 360 370 380 390
pF1KB9 EGRRMGPPVGGHRRGPSRYGPQYGHPPPPPPPPEY--GPHADSPVLMVYGLDQSKMNCDR
::: :: :. : : : : . .. :.:: :: : ::::.:
NP_612 SRYRMG----------SRDTPELVAYPLPQASSSYMHGGNPSGSVVMVSGLHQLKMNCSR
310 320 330 340 350
400 410 420 430 440 450
pF1KB9 VFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPA
:::.::::::.:::::::. ::.:.:::.: :::.::.::::: .::..:::::::: .
NP_612 VFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHS
360 370 380 390 400 410
460 470 480 490 500 510
pF1KB9 IMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFF
..:.: . ::::. :::::. :.::::.. ::.:: :: :: :::..:.:: ::::.:
NP_612 VVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFT
420 430 440 450 460 470
520 530 540 550 560 570
pF1KB9 EICDELGVKRPSSVKVFSGK-SERSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYT
..:.. : . :::..: : .. ::::::: :.::.:.: :::::.. ::: :::
NP_612 KLCNDHEVLTFIKYKVFDAKPSAKTLSGLLEWECKTDAVEALTALNHYQIRVPNGSNPYT
480 490 500 510 520 530
580
pF1KB9 LKLCFSTAQHAS
:::::::..:
NP_612 LKLCFSTSSHL
540
>>XP_011531468 (OMIM: 611208) PREDICTED: heterogeneous n (570 aa)
initn: 1674 init1: 934 opt: 1025 Z-score: 559.5 bits: 113.5 E(85289): 2e-24
Smith-Waterman score: 1791; 56.5% identity (76.3% similar) in 503 aa overlap (71-570:49-524)
50 60 70 80 90 100
pF1KB9 GGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGENYDDPHKTPA
::: ::::: . . .:: . ::. .
XP_011 ESQAKRLKTEEGEIDYSAEEGENRREATPRGGGDGGGGGRSFSQPEAGGSH----HKVSV
20 30 40 50 60 70
110 120 130 140 150 160
pF1KB9 SPVVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADN
:::::.::: ..::::::::::..:: : ::..:: :::::::::.. .: . :..:::.
XP_011 SPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADE
80 90 100 110 120 130
170 180 190 200 210 220
pF1KB9 QIYIAGHPAFVNYSTSQKISRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGP
.::::. :: :::::..:.:::..:: . :.:::..: ::.: ::.:::::.::: :
XP_011 PVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGK
140 150 160 170 180 190
230 240 250 260 270 280
pF1KB9 VQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQ
:::::::..::.::::::.:: ::.:::.:::::::.::::::::::.::::::..::.
XP_011 VQRIVIFKRNGIQAMVEFESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLNVIRNDN
200 210 220 230 240 250
290 300 310 320 330 340
pF1KB9 DTWDYTNPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHY
:.::::.: : :. : :.. :::: .::.::. . : :: :: :: :
XP_011 DSWDYTKPYL-GRRDRGKG---RQRQA-ILGEHPSSFR--HDGYGSH------GPLLPLP
260 270 280 290 300
350 360 370 380 390
pF1KB9 EGRRMGPPVGGHRRGPSRYGPQYGHPPPPPPPPEY--GPHADSPVLMVYGLDQSKMNCDR
::: :: :. : : : : . .. :.:: :: : ::::.:
XP_011 SRYRMG----------SRDTPELVAYPLPQASSSYMHGGNPSGSVVMVSGLHQLKMNCSR
310 320 330 340 350
400 410 420 430 440 450
pF1KB9 VFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPA
:::.::::::.:::::::. ::.:.:::.: :::.::.::::: .::..:::::::: .
XP_011 VFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHS
360 370 380 390 400 410
460 470 480 490 500 510
pF1KB9 IMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFF
..:.: . ::::. :::::. :.::::.. ::.:: :: :: :::..:.:: ::::.:
XP_011 VVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFT
420 430 440 450 460 470
520 530 540 550 560 570
pF1KB9 EICDELGVKRPSSVKVFSGK-SERSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYT
..:.. : . :::..: : .. ::::::: :.::.:.: :::::.. :
XP_011 KLCNDHEVLTFIKYKVFDAKPSAKTLSGLLEWECKTDAVEALTALNHYQIRVPIISKLMY
480 490 500 510 520 530
580
pF1KB9 LKLCFSTAQHAS
XP_011 PIDEERFNTRFPGTFWDHRCLHVHSSFDLLPKLYLNWLL
540 550 560 570
>>XP_005264697 (OMIM: 611208) PREDICTED: heterogeneous n (590 aa)
initn: 1674 init1: 934 opt: 1025 Z-score: 559.4 bits: 113.5 E(85289): 2e-24
Smith-Waterman score: 1791; 56.5% identity (76.3% similar) in 503 aa overlap (71-570:44-519)
50 60 70 80 90 100
pF1KB9 GGGGGRYYGGGSEGGRAPKRLKTDNAGDQHGGGGGGGGGAGAAGGGGGGENYDDPHKTPA
::: ::::: . . .:: . ::. .
XP_005 ESQAKRLKTEEGEIDYSAEEGENRREATPRGGGDGGGGGRSFSQPEAGGSH----HKVSV
20 30 40 50 60
110 120 130 140 150 160
pF1KB9 SPVVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADN
:::::.::: ..::::::::::..:: : ::..:: :::::::::.. .: . :..:::.
XP_005 SPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADE
70 80 90 100 110 120
170 180 190 200 210 220
pF1KB9 QIYIAGHPAFVNYSTSQKISRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGP
.::::. :: :::::..:.:::..:: . :.:::..: ::.: ::.:::::.::: :
XP_005 PVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGK
130 140 150 160 170 180
230 240 250 260 270 280
pF1KB9 VQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQ
:::::::..::.::::::.:: ::.:::.:::::::.::::::::::.::::::..::.
XP_005 VQRIVIFKRNGIQAMVEFESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLNVIRNDN
190 200 210 220 230 240
290 300 310 320 330 340
pF1KB9 DTWDYTNPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGGPHGGYHSHYHDEGYGPPPPHY
:.::::.: : :. : :.. :::: .::.::. . : :: :: :: :
XP_005 DSWDYTKPYL-GRRDRGKG---RQRQA-ILGEHPSSFR--HDGYGSH------GPLLPLP
250 260 270 280 290
350 360 370 380 390
pF1KB9 EGRRMGPPVGGHRRGPSRYGPQYGHPPPPPPPPEY--GPHADSPVLMVYGLDQSKMNCDR
::: :: :. : : : : . .. :.:: :: : ::::.:
XP_005 SRYRMG----------SRDTPELVAYPLPQASSSYMHGGNPSGSVVMVSGLHQLKMNCSR
300 310 320 330 340
400 410 420 430 440 450
pF1KB9 VFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPA
:::.::::::.:::::::. ::.:.:::.: :::.::.::::: .::..:::::::: .
XP_005 VFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHS
350 360 370 380 390 400
460 470 480 490 500 510
pF1KB9 IMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFF
..:.: . ::::. :::::. :.::::.. ::.:: :: :: :::..:.:: ::::.:
XP_005 VVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFT
410 420 430 440 450 460
520 530 540 550 560 570
pF1KB9 EICDELGVKRPSSVKVFSGK-SERSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYT
..:.. : . :::..: : .. ::::::: :.::.:.: :::::.. :
XP_005 KLCNDHEVLTFIKYKVFDAKPSAKTLSGLLEWECKTDAVEALTALNHYQIRVPKTGFHHV
470 480 490 500 510 520
580
pF1KB9 LKLCFSTAQHAS
XP_005 GQAGLELLDLMICPPPPSEVLGLQAWFQSLYIEALLFYIIPFIRREEHVRIYVHLYYNFK
530 540 550 560 570 580
589 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 21:27:04 2016 done: Sat Nov 5 21:27:05 2016
Total Scan time: 9.140 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]