Result of FASTA (omim) for
pFN21AE1011
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1011, 228 aa
1>>>pF1KE1011 228 - 228 aa - 228 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.8720+/-0.000303; mu= -1.1714+/- 0.019
mean_var=200.7504+/-40.881, 0's: 0 Z-trim(123.3): 18 B-trim: 593 in 1/61
Lambda= 0.090520
statistics sampled from 42920 (42940) to 42920 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.798), E-opt: 0.2 (0.503), width: 16
Scan time: 7.350
The best scores are: opt bits E(85289)
NP_036366 (OMIM: 607535) RING1 and YY1-binding pro ( 228) 1463 202.4 5.2e-52
NP_005739 (OMIM: 607534) YY1-associated factor 2 i ( 180) 528 80.2 2.5e-15
NP_001177908 (OMIM: 607534) YY1-associated factor ( 204) 371 59.8 4e-09
NP_001177909 (OMIM: 607534) YY1-associated factor ( 117) 353 57.3 1.3e-08
NP_001177906 (OMIM: 607534) YY1-associated factor ( 138) 350 56.9 2e-08
XP_016874159 (OMIM: 607534) PREDICTED: YY1-associa ( 120) 338 55.3 5.2e-08
XP_011536031 (OMIM: 607534) PREDICTED: YY1-associa ( 159) 337 55.3 7.2e-08
NP_001307009 (OMIM: 607534) YY1-associated factor ( 171) 337 55.3 7.6e-08
XP_006719248 (OMIM: 607534) PREDICTED: YY1-associa ( 177) 337 55.3 7.8e-08
XP_006719247 (OMIM: 607534) PREDICTED: YY1-associa ( 182) 337 55.3 8e-08
XP_016874158 (OMIM: 607534) PREDICTED: YY1-associa ( 187) 337 55.3 8.2e-08
XP_011536030 (OMIM: 607534) PREDICTED: YY1-associa ( 238) 338 55.5 9.1e-08
>>NP_036366 (OMIM: 607535) RING1 and YY1-binding protein (228 aa)
initn: 1463 init1: 1463 opt: 1463 Z-score: 1054.7 bits: 202.4 E(85289): 5.2e-52
Smith-Waterman score: 1463; 100.0% identity (100.0% similar) in 228 aa overlap (1-228:1-228)
10 20 30 40 50 60
pF1KE1 MTMGDKKSPTRPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MTMGDKKSPTRPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LVAQQVAQQYATPPPPKKEKKEKVEKQDKEKPEKDKEISPSVTKKNTNKKTKPKSDILKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LVAQQVAQQYATPPPPKKEKKEKVEKQDKEKPEKDKEISPSVTKKNTNKKTKPKSDILKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 PPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSS
130 140 150 160 170 180
190 200 210 220
pF1KE1 STSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF
::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 STSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF
190 200 210 220
>>NP_005739 (OMIM: 607534) YY1-associated factor 2 isofo (180 aa)
initn: 809 init1: 499 opt: 528 Z-score: 396.3 bits: 80.2 E(85289): 2.5e-15
Smith-Waterman score: 737; 56.4% identity (72.9% similar) in 225 aa overlap (3-227:1-179)
10 20 30 40 50 60
pF1KE1 MTMGDKKSPTRPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQ
::::::::::::: ::..:::.::::::::::::::::: .::::::::::::: ::
NP_005 MGDKKSPTRPKRQPKPSSDEGYWDCSVCTFRNSAEAFKCMMCDVRKGTSTRKPRPVSQ
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 LVAQQVAQQYATPPPPKKEKKEKVEKQDKEKPEKDKEISPSVTKKNTNKKTKPKSDILKD
::::::.::.. : :::::.::: ::: ::. ...:::..:::
NP_005 LVAQQVTQQFVPPTQSKKEKKDKVE---KEKSEKE-----TTSKKNSHKKT---------
60 70 80 90 100
130 140 150 160 170 180
pF1KE1 PPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSS
::::::::::.::.: ::::..:::::::::::.:
NP_005 ------------------------RPRLKNVDRSSAQHLEVTVGDLTVIITDFKEKTKSP
110 120 130
190 200 210 220
pF1KE1 STSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF
.::. :...:..::.:.:..:..: ::::.:.:. :..: ::
NP_005 PASSA-----ASADQHSQSGSSSDNTERGMSRSSSPRGEASSLNGESH
140 150 160 170 180
>>NP_001177908 (OMIM: 607534) YY1-associated factor 2 is (204 aa)
initn: 809 init1: 345 opt: 371 Z-score: 284.7 bits: 59.8 E(85289): 4e-09
Smith-Waterman score: 679; 51.0% identity (65.9% similar) in 249 aa overlap (3-227:1-203)
10 20 30 40 50
pF1KE1 MTMGDKKSPTRPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTR-------
::::::::::::: ::..:::.::::::::::::::::: .::::::::::
NP_001 MGDKKSPTRPKRQPKPSSDEGYWDCSVCTFRNSAEAFKCMMCDVRKGTSTRSTLFEVI
10 20 30 40 50
60 70 80 90
pF1KE1 -----------------KPRINSQLVAQQVAQQYATPPPPKKEKKEKVEKQDKEKPEKDK
::: ::::::::.::.. : :::::.::: ::: ::.
NP_001 VSASRTKEPLKFPISGRKPRPVSQLVAQQVTQQFVPPTQSKKEKKDKVE---KEKSEKE-
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE1 EISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTA
...:::..::: ::::::::::.:
NP_001 ----TTSKKNSHKKT---------------------------------RPRLKNVDRSSA
120 130
160 170 180 190 200 210
pF1KE1 QQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTP
:.: ::::..:::::::::::.: .::. :...:..::.:.:..:..: ::::.:
NP_001 QHLEVTVGDLTVIITDFKEKTKSPPASSA-----ASADQHSQSGSSSDNTERGMSRSSSP
140 150 160 170 180 190
220
pF1KE1 KGDMSAVNDESF
.:. :..: ::
NP_001 RGEASSLNGESH
200
>>NP_001177909 (OMIM: 607534) YY1-associated factor 2 is (117 aa)
initn: 380 init1: 352 opt: 353 Z-score: 275.5 bits: 57.3 E(85289): 1.3e-08
Smith-Waterman score: 353; 46.8% identity (75.7% similar) in 111 aa overlap (3-113:1-106)
10 20 30 40 50 60
pF1KE1 MTMGDKKSPTRPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQ
::::::::::::: ::..:::.::::::::::::::::: .:::::::::: . ...
NP_001 MGDKKSPTRPKRQPKPSSDEGYWDCSVCTFRNSAEAFKCMMCDVRKGTSTRDSKEGGK
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 LVAQQVAQQYATPPPPKKEKKEKVEKQDKEKPEKDKEISPSVTKKNTNKKTKPKSDILKD
::. ..:. . . ...: ..:. .. . ..:. .. ... . :
NP_001 LVSYSTASLGV-----RGTLRNRVGGGSSEEKKQAEYLAPGRRRNIVHRGVGPGQRSGPS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 PPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSS
NP_001 LKEA
>>NP_001177906 (OMIM: 607534) YY1-associated factor 2 is (138 aa)
initn: 553 init1: 206 opt: 350 Z-score: 272.3 bits: 56.9 E(85289): 2e-08
Smith-Waterman score: 416; 47.2% identity (66.1% similar) in 180 aa overlap (48-227:4-137)
20 30 40 50 60 70
pF1KE1 PAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPK
: . ::::: ::::::::.::.. : :
NP_001 MGDKKSPTRKPRPVSQLVAQQVTQQFVPPTQSK
10 20 30
80 90 100 110 120 130
pF1KE1 KEKKEKVEKQDKEKPEKDKEISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKT
::::.::: ::: ::. ...:::..:::
NP_001 KEKKDKVE---KEKSEKE-----TTSKKNSHKKT--------------------------
40 50
140 150 160 170 180 190
pF1KE1 SETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQN
::::::::::.::.: ::::..:::::::::::.: .::. :...:..
NP_001 -------RPRLKNVDRSSAQHLEVTVGDLTVIITDFKEKTKSPPASSA-----ASADQHS
60 70 80 90 100
200 210 220
pF1KE1 QSSSGSESTDKGSSRSSTPKGDMSAVNDESF
::.:.:..:..: ::::.:.:. :..: ::
NP_001 QSGSSSDNTERGMSRSSSPRGEASSLNGESH
110 120 130
>>XP_016874159 (OMIM: 607534) PREDICTED: YY1-associated (120 aa)
initn: 338 init1: 338 opt: 338 Z-score: 264.8 bits: 55.3 E(85289): 5.2e-08
Smith-Waterman score: 338; 88.2% identity (96.1% similar) in 51 aa overlap (3-53:1-51)
10 20 30 40 50 60
pF1KE1 MTMGDKKSPTRPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQ
::::::::::::: ::..:::.::::::::::::::::: .::::::::::
XP_016 MGDKKSPTRPKRQPKPSSDEGYWDCSVCTFRNSAEAFKCMMCDVRKGTSTRMKNHEII
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 LVAQQVAQQYATPPPPKKEKKEKVEKQDKEKPEKDKEISPSVTKKNTNKKTKPKSDILKD
XP_016 SFLKEGEKKKLDHLPVTGVLLLGNLHRSTLFEVIVSASRTKEPLKFPISGSSSGCPSGRF
60 70 80 90 100 110
>>XP_011536031 (OMIM: 607534) PREDICTED: YY1-associated (159 aa)
initn: 451 init1: 206 opt: 337 Z-score: 262.3 bits: 55.3 E(85289): 7.2e-08
Smith-Waterman score: 409; 47.5% identity (66.1% similar) in 177 aa overlap (51-227:28-158)
30 40 50 60 70 80
pF1KE1 DEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEK
: :::: ::::::::.::.. : ::::
XP_011 MVCGEGSTLFEVIVSASRTKEPLKFPISGRKPRPVSQLVAQQVTQQFVPPTQSKKEK
10 20 30 40 50
90 100 110 120 130 140
pF1KE1 KEKVEKQDKEKPEKDKEISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSET
:.:::: :: ::. ...:::..:::
XP_011 KDKVEK---EKSEKE-----TTSKKNSHKKT-----------------------------
60 70 80
150 160 170 180 190 200
pF1KE1 NHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSS
::::::::::.::.: ::::..:::::::::::.: .: :.:...:..::.
XP_011 ----RPRLKNVDRSSAQHLEVTVGDLTVIITDFKEKTKSPPAS-----SAASADQHSQSG
90 100 110 120 130
210 220
pF1KE1 SGSESTDKGSSRSSTPKGDMSAVNDESF
:.:..:..: ::::.:.:. :..: ::
XP_011 SSSDNTERGMSRSSSPRGEASSLNGESH
140 150
>>NP_001307009 (OMIM: 607534) YY1-associated factor 2 is (171 aa)
initn: 504 init1: 206 opt: 337 Z-score: 261.8 bits: 55.3 E(85289): 7.6e-08
Smith-Waterman score: 399; 47.1% identity (66.1% similar) in 174 aa overlap (54-227:43-170)
30 40 50 60 70 80
pF1KE1 FWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEK
::: ::::::::.::.. : :::::.:
NP_001 REPGYHLVEQSCWLKPLPRNLGHSLFWTVWKPRPVSQLVAQQVTQQFVPPTQSKKEKKDK
20 30 40 50 60 70
90 100 110 120 130 140
pF1KE1 VEKQDKEKPEKDKEISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSETNHT
::: :: ::. ...:::..:::
NP_001 VEK---EKSEKE-----TTSKKNSHKKT--------------------------------
80 90
150 160 170 180 190 200
pF1KE1 SRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGS
::::::::::.::.: ::::..:::::::::::.: .:: .:...:..::.:.:
NP_001 -RPRLKNVDRSSAQHLEVTVGDLTVIITDFKEKTKSPPASS-----AASADQHSQSGSSS
100 110 120 130 140
210 220
pF1KE1 ESTDKGSSRSSTPKGDMSAVNDESF
..:..: ::::.:.:. :..: ::
NP_001 DNTERGMSRSSSPRGEASSLNGESH
150 160 170
>>XP_006719248 (OMIM: 607534) PREDICTED: YY1-associated (177 aa)
initn: 451 init1: 206 opt: 337 Z-score: 261.6 bits: 55.3 E(85289): 7.8e-08
Smith-Waterman score: 409; 47.5% identity (66.1% similar) in 177 aa overlap (51-227:46-176)
30 40 50 60 70 80
pF1KE1 DEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEK
: :::: ::::::::.::.. : ::::
XP_006 VLLLGNLHRSTLFEVIVSASRTKEPLKFPISGRKPRPVSQLVAQQVTQQFVPPTQSKKEK
20 30 40 50 60 70
90 100 110 120 130 140
pF1KE1 KEKVEKQDKEKPEKDKEISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSET
:.:::: :: ::. ...:::..:::
XP_006 KDKVEK---EKSEKE-----TTSKKNSHKKT-----------------------------
80 90
150 160 170 180 190 200
pF1KE1 NHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSS
::::::::::.::.: ::::..:::::::::::.: .: :.:...:..::.
XP_006 ----RPRLKNVDRSSAQHLEVTVGDLTVIITDFKEKTKSPPAS-----SAASADQHSQSG
100 110 120 130 140
210 220
pF1KE1 SGSESTDKGSSRSSTPKGDMSAVNDESF
:.:..:..: ::::.:.:. :..: ::
XP_006 SSSDNTERGMSRSSSPRGEASSLNGESH
150 160 170
>>XP_006719247 (OMIM: 607534) PREDICTED: YY1-associated (182 aa)
initn: 474 init1: 206 opt: 337 Z-score: 261.4 bits: 55.3 E(85289): 8e-08
Smith-Waterman score: 409; 47.5% identity (66.1% similar) in 177 aa overlap (51-227:51-181)
30 40 50 60 70 80
pF1KE1 DEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEK
: :::: ::::::::.::.. : ::::
XP_006 VLLLGNLHRSTLFEVIVSASRTKEPLKFPISGRKPRPVSQLVAQQVTQQFVPPTQSKKEK
30 40 50 60 70 80
90 100 110 120 130 140
pF1KE1 KEKVEKQDKEKPEKDKEISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSET
:.:::: :: ::. ...:::..:::
XP_006 KDKVEK---EKSEKE-----TTSKKNSHKKT-----------------------------
90 100
150 160 170 180 190 200
pF1KE1 NHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSS
::::::::::.::.: ::::..:::::::::::.: .: :.:...:..::.
XP_006 ----RPRLKNVDRSSAQHLEVTVGDLTVIITDFKEKTKSPPAS-----SAASADQHSQSG
110 120 130 140 150
210 220
pF1KE1 SGSESTDKGSSRSSTPKGDMSAVNDESF
:.:..:..: ::::.:.:. :..: ::
XP_006 SSSDNTERGMSRSSSPRGEASSLNGESH
160 170 180
228 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 21:11:41 2016 done: Sat Nov 5 21:11:42 2016
Total Scan time: 7.350 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]