Result of FASTA (omim) for
pFN21AE0009
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0009, 643 aa
1>>>pF1KE0009 643 - 643 aa - 643 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.1371+/-0.000458; mu= -2.6745+/- 0.028
mean_var=317.9434+/-65.177, 0's: 0 Z-trim(120.4): 237 B-trim: 1472 in 1/55
Lambda= 0.071928
statistics sampled from 35390 (35664) to 35390 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.742), E-opt: 0.2 (0.418), width: 16
Scan time: 12.270
The best scores are: opt bits E(85289)
NP_001184225 (OMIM: 603479) extracellular matrix p ( 643) 4307 461.2 5.3e-129
NP_001184224 (OMIM: 603479) extracellular matrix p ( 677) 4167 446.7 1.3e-124
NP_001384 (OMIM: 603479) extracellular matrix prot ( 699) 3059 331.7 5.4e-90
XP_016869865 (OMIM: 603479) PREDICTED: extracellul ( 485) 1683 188.8 4e-47
XP_016869866 (OMIM: 603479) PREDICTED: extracellul ( 364) 1157 134.1 8.8e-31
XP_011538979 (OMIM: 608661) PREDICTED: podocan iso ( 402) 493 65.2 5.2e-10
XP_005270514 (OMIM: 608661) PREDICTED: podocan iso ( 613) 493 65.4 7.1e-10
NP_001186009 (OMIM: 608661) podocan isoform 2 [Hom ( 642) 493 65.4 7.3e-10
NP_001186010 (OMIM: 608661) podocan isoform 2 [Hom ( 642) 493 65.4 7.3e-10
XP_016855783 (OMIM: 608661) PREDICTED: podocan iso ( 652) 493 65.4 7.4e-10
NP_714914 (OMIM: 608661) podocan isoform 1 [Homo s ( 661) 493 65.4 7.5e-10
NP_060150 (OMIM: 603932,607850,608135) asporin iso ( 379) 483 64.1 1e-09
NP_001702 (OMIM: 300106,301870) biglycan prepropro ( 368) 458 61.5 6.1e-09
XP_016885213 (OMIM: 300106,301870) PREDICTED: bigl ( 368) 458 61.5 6.1e-09
NP_001911 (OMIM: 125255,610048) decorin isoform a ( 359) 454 61.1 7.9e-09
XP_016874406 (OMIM: 125255,610048) PREDICTED: deco ( 359) 454 61.1 7.9e-09
XP_005268750 (OMIM: 125255,610048) PREDICTED: deco ( 359) 454 61.1 7.9e-09
NP_598010 (OMIM: 125255,610048) decorin isoform a ( 359) 454 61.1 7.9e-09
XP_006719333 (OMIM: 125255,610048) PREDICTED: deco ( 359) 454 61.1 7.9e-09
NP_008966 (OMIM: 217300,603288) keratocan precurso ( 352) 445 60.2 1.5e-08
NP_002014 (OMIM: 600245) fibromodulin precursor [H ( 376) 434 59.1 3.5e-08
NP_958505 (OMIM: 601914) prolargin precursor [Homo ( 382) 430 58.6 4.7e-08
NP_002716 (OMIM: 601914) prolargin precursor [Homo ( 382) 430 58.6 4.7e-08
NP_938205 (OMIM: 604808,615271) leucine-rich repea ( 649) 378 53.5 2.9e-06
XP_011527507 (OMIM: 604808,615271) PREDICTED: leuc ( 649) 378 53.5 2.9e-06
XP_011527506 (OMIM: 604808,615271) PREDICTED: leuc ( 649) 378 53.5 2.9e-06
XP_005260739 (OMIM: 604808,615271) PREDICTED: leuc ( 649) 378 53.5 2.9e-06
NP_037413 (OMIM: 604808,615271) leucine-rich repea ( 649) 378 53.5 2.9e-06
NP_001180264 (OMIM: 603932,607850,608135) asporin ( 242) 356 50.8 6.8e-06
NP_001073982 (OMIM: 603104) carboxypeptidase N sub ( 545) 364 51.9 7e-06
XP_005269337 (OMIM: 603104) PREDICTED: carboxypept ( 545) 364 51.9 7e-06
NP_001278917 (OMIM: 603104) carboxypeptidase N sub ( 545) 364 51.9 7e-06
NP_001333075 (OMIM: 604807) leucine-rich repeat tr ( 660) 363 51.9 8.6e-06
XP_016876618 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 363 51.9 8.6e-06
NP_037363 (OMIM: 604807) leucine-rich repeat trans ( 660) 363 51.9 8.6e-06
XP_016876624 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 363 51.9 8.6e-06
XP_011534913 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 363 51.9 8.6e-06
NP_001333074 (OMIM: 604807) leucine-rich repeat tr ( 660) 363 51.9 8.6e-06
XP_016876620 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 363 51.9 8.6e-06
XP_016876622 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 363 51.9 8.6e-06
XP_005267547 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 363 51.9 8.6e-06
NP_001333073 (OMIM: 604807) leucine-rich repeat tr ( 660) 363 51.9 8.6e-06
NP_001333072 (OMIM: 604807) leucine-rich repeat tr ( 660) 363 51.9 8.6e-06
XP_016876623 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 363 51.9 8.6e-06
XP_016876621 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 363 51.9 8.6e-06
XP_016876619 (OMIM: 604807) PREDICTED: leucine-ric ( 660) 363 51.9 8.6e-06
NP_004479 (OMIM: 173511) platelet glycoprotein V p ( 560) 361 51.6 8.8e-06
XP_011543185 (OMIM: 604806) PREDICTED: leucine-ric ( 674) 355 51.1 1.6e-05
NP_037412 (OMIM: 604806) leucine-rich repeat trans ( 674) 355 51.1 1.6e-05
XP_005273918 (OMIM: 604806) PREDICTED: leucine-ric ( 674) 355 51.1 1.6e-05
>>NP_001184225 (OMIM: 603479) extracellular matrix prote (643 aa)
initn: 4307 init1: 4307 opt: 4307 Z-score: 2437.0 bits: 461.2 E(85289): 5.3e-129
Smith-Waterman score: 4307; 99.8% identity (99.8% similar) in 643 aa overlap (1-643:1-643)
10 20 30 40 50 60
pF1KE0 MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIPQTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
NP_001 MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIQQTTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSATEQREPTNLLHKQLPPPQVGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSATEQREPTNLLHKQLPPPQVGM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLYSEGDSRGGDRKQRPGEERRLAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLYSEGDSRGGDRKQRPGEERRLAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 QQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRMPSRSPLPAPPRGTLRLPSGCSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRMPSRSPLPAPPRGTLRLPSGCSL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 SYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITSS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 GIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQLVT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEITE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEITE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 ICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 LLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDLKS
550 560 570 580 590 600
610 620 630 640
pF1KE0 IPPGIQEMKALHFLRLNNNKIRCVSDAVLETVTNRSDVAFPLW
:::::::::::::::::::::::::::::::::::::::::::
NP_001 IPPGIQEMKALHFLRLNNNKIRCVSDAVLETVTNRSDVAFPLW
610 620 630 640
>>NP_001184224 (OMIM: 603479) extracellular matrix prote (677 aa)
initn: 4540 init1: 4167 opt: 4167 Z-score: 2358.2 bits: 446.7 E(85289): 1.3e-124
Smith-Waterman score: 4167; 99.5% identity (99.7% similar) in 624 aa overlap (1-624:1-624)
10 20 30 40 50 60
pF1KE0 MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIPQTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
NP_001 MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIQQTTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSATEQREPTNLLHKQLPPPQVGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSATEQREPTNLLHKQLPPPQVGM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLYSEGDSRGGDRKQRPGEERRLAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLYSEGDSRGGDRKQRPGEERRLAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 QQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRMPSRSPLPAPPRGTLRLPSGCSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRMPSRSPLPAPPRGTLRLPSGCSL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 SYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITSS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 GIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQLVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQLVT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEITE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEITE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 ICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 LLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDLKS
550 560 570 580 590 600
610 620 630 640
pF1KE0 IPPGIQEMKALHFLRLNNNKIRCVSDAVLETVTNRSDVAFPLW
:::::::::::::::::::::: .
NP_001 IPPGIQEMKALHFLRLNNNKIRNILPEEICNAEEDDDSNLEHLHLENNYIKIREIPSYTF
610 620 630 640 650 660
>>NP_001384 (OMIM: 603479) extracellular matrix protein (699 aa)
initn: 4526 init1: 3044 opt: 3059 Z-score: 1736.6 bits: 331.7 E(85289): 5.4e-90
Smith-Waterman score: 4113; 96.1% identity (96.3% similar) in 646 aa overlap (1-624:1-646)
10 20 30 40 50 60
pF1KE0 MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIPQTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
NP_001 MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIQQTTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
70 80 90 100 110 120
130 140 150 160
pF1KE0 CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSAT--------------------
::::::::::::::::::::::::::::::::::::::::
NP_001 CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSATVSYSLLSGIALNDRNEFSGD
130 140 150 160 170 180
170 180 190 200 210
pF1KE0 --EQREPTNLLHKQLPPPQVGMDRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSEQREPTNLLHKQLPPPQVGMDRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLY
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE0 SEGDSRGGDRKQRPGEERRLAHQQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEGDSRGGDRKQRPGEERRLAHQQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRM
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE0 PSRSPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSRSPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE0 EAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELK
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE0 VNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIP
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE0 QGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESI
490 500 510 520 530 540
520 530 540 550 560 570
pF1KE0 DLSYNKLYHVPSYLPKSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLSYNKLYHVPSYLPKSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDR
550 560 570 580 590 600
580 590 600 610 620 630
pF1KE0 VSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRCVSDAVLETVTNRSDV
:::::::::::::::::::::::::::::::::::::::::::: .
NP_001 VSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRNILPEEICNAEEDDDS
610 620 630 640 650 660
640
pF1KE0 AFPLW
NP_001 NLEHLHLENNYIKIREIPSYTFSCIRSYSSIVLKPQNIK
670 680 690
>>XP_016869865 (OMIM: 603479) PREDICTED: extracellular m (485 aa)
initn: 1671 init1: 1671 opt: 1683 Z-score: 967.0 bits: 188.8 E(85289): 4e-47
Smith-Waterman score: 2740; 88.1% identity (90.2% similar) in 479 aa overlap (1-457:1-468)
10 20 30 40 50 60
pF1KE0 MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIPQTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_016 MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIQQTTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
70 80 90 100 110 120
130 140 150 160
pF1KE0 CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSAT--------------------
::::::::::::::::::::::::::::::::::::::::
XP_016 CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSATVSYSLLSGIALNDRNEFSGD
130 140 150 160 170 180
170 180 190 200 210
pF1KE0 --EQREPTNLLHKQLPPPQVGMDRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSEQREPTNLLHKQLPPPQVGMDRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLY
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE0 SEGDSRGGDRKQRPGEERRLAHQQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEGDSRGGDRKQRPGEERRLAHQQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRM
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE0 PSRSPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSRSPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE0 EAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELK
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE0 VNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIP
::::::::::::::: . .::... .:: : ::. : : . : ..
XP_016 VNENNLQAIDEESLSG-----SYYSQGNKFT---TNP---KYLKNYAKYSLHCHVFCVMD
430 440 450 460
460 470 480 490 500 510
pF1KE0 QGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESI
XP_016 RQFCRFFVATNQCHVC
470 480
>>XP_016869866 (OMIM: 603479) PREDICTED: extracellular m (364 aa)
initn: 2381 init1: 1142 opt: 1157 Z-score: 673.6 bits: 134.1 E(85289): 8.8e-31
Smith-Waterman score: 2211; 92.9% identity (93.5% similar) in 353 aa overlap (1-331:1-353)
10 20 30 40 50 60
pF1KE0 MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIPQTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_016 MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIQQTTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
70 80 90 100 110 120
130 140 150 160
pF1KE0 CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSAT--------------------
::::::::::::::::::::::::::::::::::::::::
XP_016 CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSATVSYSLLSGIALNDRNEFSGD
130 140 150 160 170 180
170 180 190 200 210
pF1KE0 --EQREPTNLLHKQLPPPQVGMDRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSEQREPTNLLHKQLPPPQVGMDRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLY
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE0 SEGDSRGGDRKQRPGEERRLAHQQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEGDSRGGDRKQRPGEERRLAHQQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRM
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE0 PSRSPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPD
:::::::::::::::::::::::::::::::::::::::::::::::::::..
XP_016 PSRSPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTASEEVNAFE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE0 EAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELK
XP_016 YGWK
>>XP_011538979 (OMIM: 608661) PREDICTED: podocan isoform (402 aa)
initn: 705 init1: 366 opt: 493 Z-score: 300.7 bits: 65.2 E(85289): 5.2e-10
Smith-Waterman score: 493; 31.2% identity (63.9% similar) in 324 aa overlap (312-634:18-336)
290 300 310 320 330 340
pF1KE0 SPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAF
: ..: : . .:.: .:.. .:: ::
XP_011 MFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAF
10 20 30 40
350 360 370 380 390 400
pF1KE0 NGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNE
. : .:..: :..: .:. :. ..: :..: :....::: ..:. :: .: :....
XP_011 SELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEK
50 60 70 80 90 100
410 420 430 440 450 460
pF1KE0 NNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGL
: ....: . :. . .: : :..:.: : ...::::. :: : ..: .: .. .:.::
XP_011 NAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGL
110 120 130 140 150 160
470 480 490 500 510 520
pF1KE0 PGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLS
: .. :.. .::: : . : : .. . : ::.: .. :. . . :.:.:::
XP_011 PRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLS
170 180 190 200 210 220
530 540 550 560 570 580
pF1KE0 YNKLYHVPSYLPKSLLHLVLLGNQIERIP-GYVFGHMEPGLEYLYLSFNKLADDGMDRVS
:.:. .: ::... : . :.. . : . : . :. :::. :.: . .. .
XP_011 GNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQ--LRELYLTSNRLRSRALGPRA
230 240 250 260 270 280
590 600 610 620 630 640
pF1KE0 FYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRCVSDAVLETVTNRSDVAF
. : :. : . :.: :: :. : .:..: :.:::: : ..... :
XP_011 WVDLAH-LQLLDIAGNQLTEIPEGLPE--SLEYLYLQNNKISAVPANAFDSTPNLKGIFL
290 300 310 320 330 340
pF1KE0 PLW
XP_011 RFNKLAVGSVVDSAFRRLKHLQVLDIEGNLEFGDISKDRGRLGKEKEEEEEEEEEEEETR
350 360 370 380 390 400
>>XP_005270514 (OMIM: 608661) PREDICTED: podocan isoform (613 aa)
initn: 705 init1: 366 opt: 493 Z-score: 298.3 bits: 65.4 E(85289): 7.1e-10
Smith-Waterman score: 493; 31.2% identity (63.9% similar) in 324 aa overlap (312-634:229-547)
290 300 310 320 330 340
pF1KE0 SPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAF
: ..: : . .:.: .:.. .:: ::
XP_005 HNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAF
200 210 220 230 240 250
350 360 370 380 390 400
pF1KE0 NGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNE
. : .:..: :..: .:. :. ..: :..: :....::: ..:. :: .: :....
XP_005 SELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEK
260 270 280 290 300 310
410 420 430 440 450 460
pF1KE0 NNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGL
: ....: . :. . .: : :..:.: : ...::::. :: : ..: .: .. .:.::
XP_005 NAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGL
320 330 340 350 360 370
470 480 490 500 510 520
pF1KE0 PGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLS
: .. :.. .::: : . : : .. . : ::.: .. :. . . :.:.:::
XP_005 PRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLS
380 390 400 410 420 430
530 540 550 560 570 580
pF1KE0 YNKLYHVPSYLPKSLLHLVLLGNQIERIP-GYVFGHMEPGLEYLYLSFNKLADDGMDRVS
:.:. .: ::... : . :.. . : . : . :. :::. :.: . .. .
XP_005 GNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQ--LRELYLTSNRLRSRALGPRA
440 450 460 470 480 490
590 600 610 620 630 640
pF1KE0 FYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRCVSDAVLETVTNRSDVAF
. : :. : . :.: :: :. : .:..: :.:::: : ..... :
XP_005 WVDLAH-LQLLDIAGNQLTEIPEGLPE--SLEYLYLQNNKISAVPANAFDSTPNLKGIFL
500 510 520 530 540 550
pF1KE0 PLW
XP_005 RFNKLAVGSVVDSAFRRLKHLQVLDIEGNLEFGDISKDRGRLGKEKEEEEEEEEEEEETR
560 570 580 590 600 610
>>NP_001186009 (OMIM: 608661) podocan isoform 2 [Homo sa (642 aa)
initn: 705 init1: 366 opt: 493 Z-score: 298.0 bits: 65.4 E(85289): 7.3e-10
Smith-Waterman score: 493; 31.2% identity (63.9% similar) in 324 aa overlap (312-634:258-576)
290 300 310 320 330 340
pF1KE0 SPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAF
: ..: : . .:.: .:.. .:: ::
NP_001 HNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAF
230 240 250 260 270 280
350 360 370 380 390 400
pF1KE0 NGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNE
. : .:..: :..: .:. :. ..: :..: :....::: ..:. :: .: :....
NP_001 SELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEK
290 300 310 320 330 340
410 420 430 440 450 460
pF1KE0 NNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGL
: ....: . :. . .: : :..:.: : ...::::. :: : ..: .: .. .:.::
NP_001 NAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGL
350 360 370 380 390 400
470 480 490 500 510 520
pF1KE0 PGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLS
: .. :.. .::: : . : : .. . : ::.: .. :. . . :.:.:::
NP_001 PRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLS
410 420 430 440 450 460
530 540 550 560 570 580
pF1KE0 YNKLYHVPSYLPKSLLHLVLLGNQIERIP-GYVFGHMEPGLEYLYLSFNKLADDGMDRVS
:.:. .: ::... : . :.. . : . : . :. :::. :.: . .. .
NP_001 GNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQ--LRELYLTSNRLRSRALGPRA
470 480 490 500 510 520
590 600 610 620 630 640
pF1KE0 FYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRCVSDAVLETVTNRSDVAF
. : :. : . :.: :: :. : .:..: :.:::: : ..... :
NP_001 WVDLAH-LQLLDIAGNQLTEIPEGLPE--SLEYLYLQNNKISAVPANAFDSTPNLKGIFL
530 540 550 560 570 580
pF1KE0 PLW
NP_001 RFNKLAVGSVVDSAFRRLKHLQVLDIEGNLEFGDISKDRGRLGKEKEEEEEEEEEEEETR
590 600 610 620 630 640
>>NP_001186010 (OMIM: 608661) podocan isoform 2 [Homo sa (642 aa)
initn: 705 init1: 366 opt: 493 Z-score: 298.0 bits: 65.4 E(85289): 7.3e-10
Smith-Waterman score: 493; 31.2% identity (63.9% similar) in 324 aa overlap (312-634:258-576)
290 300 310 320 330 340
pF1KE0 SPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAF
: ..: : . .:.: .:.. .:: ::
NP_001 HNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAF
230 240 250 260 270 280
350 360 370 380 390 400
pF1KE0 NGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNE
. : .:..: :..: .:. :. ..: :..: :....::: ..:. :: .: :....
NP_001 SELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEK
290 300 310 320 330 340
410 420 430 440 450 460
pF1KE0 NNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGL
: ....: . :. . .: : :..:.: : ...::::. :: : ..: .: .. .:.::
NP_001 NAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGL
350 360 370 380 390 400
470 480 490 500 510 520
pF1KE0 PGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLS
: .. :.. .::: : . : : .. . : ::.: .. :. . . :.:.:::
NP_001 PRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLS
410 420 430 440 450 460
530 540 550 560 570 580
pF1KE0 YNKLYHVPSYLPKSLLHLVLLGNQIERIP-GYVFGHMEPGLEYLYLSFNKLADDGMDRVS
:.:. .: ::... : . :.. . : . : . :. :::. :.: . .. .
NP_001 GNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQ--LRELYLTSNRLRSRALGPRA
470 480 490 500 510 520
590 600 610 620 630 640
pF1KE0 FYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRCVSDAVLETVTNRSDVAF
. : :. : . :.: :: :. : .:..: :.:::: : ..... :
NP_001 WVDLAH-LQLLDIAGNQLTEIPEGLPE--SLEYLYLQNNKISAVPANAFDSTPNLKGIFL
530 540 550 560 570 580
pF1KE0 PLW
NP_001 RFNKLAVGSVVDSAFRRLKHLQVLDIEGNLEFGDISKDRGRLGKEKEEEEEEEEEEEETR
590 600 610 620 630 640
>>XP_016855783 (OMIM: 608661) PREDICTED: podocan isoform (652 aa)
initn: 705 init1: 366 opt: 493 Z-score: 297.9 bits: 65.4 E(85289): 7.4e-10
Smith-Waterman score: 493; 31.2% identity (63.9% similar) in 324 aa overlap (312-634:268-586)
290 300 310 320 330 340
pF1KE0 SPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAF
: ..: : . .:.: .:.. .:: ::
XP_016 HNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAF
240 250 260 270 280 290
350 360 370 380 390 400
pF1KE0 NGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNE
. : .:..: :..: .:. :. ..: :..: :....::: ..:. :: .: :....
XP_016 SELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEK
300 310 320 330 340 350
410 420 430 440 450 460
pF1KE0 NNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGL
: ....: . :. . .: : :..:.: : ...::::. :: : ..: .: .. .:.::
XP_016 NAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGL
360 370 380 390 400 410
470 480 490 500 510 520
pF1KE0 PGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLS
: .. :.. .::: : . : : .. . : ::.: .. :. . . :.:.:::
XP_016 PRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLS
420 430 440 450 460 470
530 540 550 560 570 580
pF1KE0 YNKLYHVPSYLPKSLLHLVLLGNQIERIP-GYVFGHMEPGLEYLYLSFNKLADDGMDRVS
:.:. .: ::... : . :.. . : . : . :. :::. :.: . .. .
XP_016 GNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQ--LRELYLTSNRLRSRALGPRA
480 490 500 510 520 530
590 600 610 620 630 640
pF1KE0 FYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRCVSDAVLETVTNRSDVAF
. : :. : . :.: :: :. : .:..: :.:::: : ..... :
XP_016 WVDLAH-LQLLDIAGNQLTEIPEGLPE--SLEYLYLQNNKISAVPANAFDSTPNLKGIFL
540 550 560 570 580 590
pF1KE0 PLW
XP_016 RFNKLAVGSVVDSAFRRLKHLQVLDIEGNLEFGDISKDRGRLGKEKEEEEEEEEEEEETR
600 610 620 630 640 650
643 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 08:30:30 2016 done: Fri Nov 4 08:30:32 2016
Total Scan time: 12.270 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]