Result of FASTA (omim) for
pFN21AB6985
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6985, 219 aa
1>>>pF1KB6985 219 - 219 aa - 219 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5224+/-0.00034; mu= 10.7592+/- 0.021
mean_var=160.6866+/-32.030, 0's: 0 Z-trim(119.4): 20 B-trim: 695 in 1/56
Lambda= 0.101178
statistics sampled from 33456 (33478) to 33456 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.393), width: 16
Scan time: 5.820
The best scores are: opt bits E(85289)
NP_057494 (OMIM: 610900) charged multivesicular bo ( 219) 1406 216.3 3.2e-56
NP_001182465 (OMIM: 610900) charged multivesicular ( 171) 1057 165.2 6e-41
NP_054888 (OMIM: 610051) charged multivesicular bo ( 265) 264 49.7 5.6e-06
NP_789782 (OMIM: 605387,610897) charged multivesic ( 224) 245 46.8 3.4e-05
NP_689497 (OMIM: 610899) charged multivesicular bo ( 233) 207 41.3 0.0016
NP_078867 (OMIM: 610901) charged multivesicular bo ( 201) 193 39.2 0.0061
>>NP_057494 (OMIM: 610900) charged multivesicular body p (219 aa)
initn: 1406 init1: 1406 opt: 1406 Z-score: 1130.2 bits: 216.3 E(85289): 3.2e-56
Smith-Waterman score: 1406; 100.0% identity (100.0% similar) in 219 aa overlap (1-219:1-219)
10 20 30 40 50 60
pF1KB6 MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDS
130 140 150 160 170 180
190 200 210
pF1KB6 SYLDEAASAPAIPEGVPTDTKNKDGVLVDEFGLPQIPAS
:::::::::::::::::::::::::::::::::::::::
NP_057 SYLDEAASAPAIPEGVPTDTKNKDGVLVDEFGLPQIPAS
190 200 210
>>NP_001182465 (OMIM: 610900) charged multivesicular bod (171 aa)
initn: 1057 init1: 1057 opt: 1057 Z-score: 856.2 bits: 165.2 E(85289): 6e-41
Smith-Waterman score: 1057; 100.0% identity (100.0% similar) in 165 aa overlap (1-165:1-165)
10 20 30 40 50 60
pF1KB6 MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDS
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAGWSSGG
130 140 150 160 170
190 200 210
pF1KB6 SYLDEAASAPAIPEGVPTDTKNKDGVLVDEFGLPQIPAS
>>NP_054888 (OMIM: 610051) charged multivesicular body p (265 aa)
initn: 236 init1: 156 opt: 264 Z-score: 228.4 bits: 49.7 E(85289): 5.6e-06
Smith-Waterman score: 264; 28.9% identity (64.0% similar) in 225 aa overlap (1-216:47-260)
10 20 30
pF1KB6 MNRLFGKAKPKAPPPSLTDCIGTVDSRAES
..:::::.: : :. . : . .
NP_054 VMRHHPPRSKAEVWRTLRGGGGRGELAMSGLGRLFGKGK-KEKGPTPEEAIQKLKETEKI
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB6 IDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFNME
. :: :. : ..... .. .:: :. ::..:..:. .::: ::: . ..
NP_054 LIKKQEFLEQ---KIQQELQTAKKYGTKN--KRAALQALRRKKRFEQQ---LAQTDGTLS
80 90 100 110 120
100 110 120 130 140
pF1KB6 QANYTIQSLKDTKTTVDA---MKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQE
.. ...... :.... :.:... :::::... ::....:. .. ...: :..:..
NP_054 TLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVAQQISD
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB6 ALSRSYGT-PELDEDDLEAELDALGDELLADEDSSYLDE----AASAPAIPEG-VPTDTK
:.:: .: ..:::.: ::. : .: ::.: . :. ... :..: .:.
NP_054 AISRPMGFGDDVDEDELLEELEELEQEELAQELLNVGDKEEEPSVKLPSVPSTHLPAGPA
190 200 210 220 230 240
210
pF1KB6 NKDGVLVDEFGLPQIPAS
: : :: .: :.
NP_054 PK--VDEDEEALKQLAEWVS
250 260
>>NP_789782 (OMIM: 605387,610897) charged multivesicular (224 aa)
initn: 257 init1: 142 opt: 245 Z-score: 214.2 bits: 46.8 E(85289): 3.4e-05
Smith-Waterman score: 245; 29.7% identity (63.2% similar) in 212 aa overlap (3-203:6-206)
10 20 30 40 50
pF1KB6 MNRLFGKAKPKAPP--PSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREG
.::: . :: :. . : . . : ..:: :. : .... ..
NP_789 MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEK---KIEQELTAAKKH
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 PAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMK-LG--
.:: :. ::..::.:. ::.: ::: . .. .. ..:....:.....: .:
NP_789 GTKN--KRAALQALKRKKRYEKQ---LAQIDGTLSTIEFQREALENANTNTEVLKNMGYA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 VKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGT-PELDEDDLEAELDALG
.: :: :. .. ::....:.... :..: :.::. :.:. : :.:::.: :::. :
NP_789 AKAMKAAHDNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELE
120 130 140 150 160 170
180 190 200 210
pF1KB6 DELLADEDSSYLD----EAASAPAIPE-GVPTDTKNKDGVLVDEFGLPQIPAS
.: : :.. :. :.. : .: ..:. .:
NP_789 QEEL---DKNLLEISGPETVPLPNVPSIALPSKPAKKKEEEDDDMKELENWAGSM
180 190 200 210 220
>>NP_689497 (OMIM: 610899) charged multivesicular body p (233 aa)
initn: 125 init1: 85 opt: 207 Z-score: 184.1 bits: 41.3 E(85289): 0.0016
Smith-Waterman score: 207; 25.2% identity (64.1% similar) in 206 aa overlap (6-206:12-203)
10 20 30 40 50
pF1KB6 MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMRE
:..: .: : : . . . : . :: :. .. . .: ..
NP_689 MSKLGKFFKGGGSSKSRAAP-SPQEALVRLRETEEMLGKKQEYLENRI---QREIALAKK
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 GPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMK-LG-
..: :. ::..::.:. .:.: :.: . .. .. ..:....:...... .:
NP_689 HGTQN--KRAALQALKRKKRFEKQ---LTQIDGTLSTIEFQREALENSHTNTEVLRNMGF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 -VKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGT-PELDEDDLEAELDAL
.: ::...... ...:.::.... .... :.::.::.:. : ..:::.: :::. :
NP_689 AAKAMKSVHENMDLNKIDDLMQEITEQQDIAQEISEAFSQRVGFGDDFDEDELMAELEEL
120 130 140 150 160 170
180 190 200 210
pF1KB6 GDELLADEDSSYLDEAASAPAIPEG-VPTDTKNKDGVLVDEFGLPQIPAS
.: : . .. : .: . .:.. . : :.
NP_689 EQEELNKKMTN-----IRLPNVPSSSLPAQPNRKPGMSSTARRSRAASSQRAEEEDDDIK
180 190 200 210 220
NP_689 QLAAWAT
230
>>NP_078867 (OMIM: 610901) charged multivesicular body p (201 aa)
initn: 116 init1: 46 opt: 193 Z-score: 173.8 bits: 39.2 E(85289): 0.0061
Smith-Waterman score: 194; 24.5% identity (57.5% similar) in 212 aa overlap (1-208:1-198)
10 20 30 40 50
pF1KB6 MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKM-REGPAKN
:. :::. : .. : . .. ... . .:. .: . . ... :.:
NP_078 MGNLFGRKK-QSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGR---
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 MVKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKA
:..: .::.::. :: : .: ..: .:. . .......: . ..:
NP_078 --KERAKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 YKQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADED
.. ..:...: . :. .. .: .:.: :. :. : : ::: . ::.:. .: .
NP_078 HQVMSIEEVERILDETQEAVEYQRQIDELLAGSF-TQE-DEDAILEELSAITQEQIE---
120 130 140 150 160
180 190 200 210
pF1KB6 SSYLDEAASAP---AIPEGVPTDTKNKDGVLVDEFGLPQIPAS
: :. : : :::.::. .. ... ::
NP_078 ---LPEVPSEPLPEKIPENVPVKARPRQAELVAAS
170 180 190 200
219 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:24:05 2016 done: Fri Nov 4 10:24:06 2016
Total Scan time: 5.820 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]