Result of FASTA (omim) for
pFN21AB6895
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6895, 184 aa
1>>>pF1KB6895 184 - 184 aa - 184 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4623+/-0.000548; mu= 11.9349+/- 0.034
mean_var=77.6381+/-16.020, 0's: 0 Z-trim(107.8): 415 B-trim: 836 in 2/51
Lambda= 0.145558
statistics sampled from 15342 (15823) to 15342 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.539), E-opt: 0.2 (0.186), width: 16
Scan time: 4.740
The best scores are: opt bits E(85289)
NP_005605 (OMIM: 601293) GTP-binding protein Rheb ( 184) 1162 253.8 1.1e-67
XP_011514759 (OMIM: 601293) PREDICTED: GTP-binding ( 173) 1064 233.2 1.7e-61
NP_002877 (OMIM: 179541) ras-related protein Rap-2 ( 183) 441 102.4 4.2e-22
NP_056461 (OMIM: 179530) ras-related protein Rap-1 ( 184) 441 102.4 4.2e-22
NP_001010942 (OMIM: 179530) ras-related protein Ra ( 184) 441 102.4 4.2e-22
NP_066361 (OMIM: 179540) ras-related protein Rap-2 ( 183) 430 100.1 2.1e-21
XP_016857452 (OMIM: 179520) PREDICTED: ras-related ( 184) 426 99.3 3.8e-21
XP_016857451 (OMIM: 179520) PREDICTED: ras-related ( 184) 426 99.3 3.8e-21
XP_016857453 (OMIM: 179520) PREDICTED: ras-related ( 184) 426 99.3 3.8e-21
NP_002875 (OMIM: 179520) ras-related protein Rap-1 ( 184) 426 99.3 3.8e-21
NP_001010935 (OMIM: 179520) ras-related protein Ra ( 184) 426 99.3 3.8e-21
NP_001278825 (OMIM: 179520) ras-related protein Ra ( 184) 426 99.3 3.8e-21
XP_016857450 (OMIM: 179520) PREDICTED: ras-related ( 195) 410 95.9 4e-20
XP_016857449 (OMIM: 179520) PREDICTED: ras-related ( 195) 410 95.9 4e-20
NP_060064 (OMIM: 607863) GTP-binding protein Di-Ra ( 199) 404 94.7 9.8e-20
XP_011518955 (OMIM: 109800,114480,137215,163200,19 ( 188) 393 92.4 4.7e-19
NP_004976 (OMIM: 109800,114480,137215,163200,19007 ( 188) 393 92.4 4.7e-19
NP_006261 (OMIM: 165090) ras-related protein R-Ras ( 218) 385 90.7 1.7e-18
NP_660156 (OMIM: 607862) GTP-binding protein Di-Ra ( 198) 383 90.3 2.1e-18
XP_011526015 (OMIM: 607862) PREDICTED: GTP-binding ( 232) 383 90.3 2.4e-18
XP_011513768 (OMIM: 179550) PREDICTED: ras-related ( 206) 382 90.1 2.5e-18
XP_006715825 (OMIM: 179550) PREDICTED: ras-related ( 206) 382 90.1 2.5e-18
NP_005393 (OMIM: 179550) ras-related protein Ral-A ( 206) 382 90.1 2.5e-18
NP_036382 (OMIM: 600098) ras-related protein R-Ras ( 204) 378 89.2 4.4e-18
XP_006719132 (OMIM: 109800,114480,137215,163200,19 ( 189) 377 89.0 4.8e-18
NP_203524 (OMIM: 109800,114480,137215,163200,19007 ( 189) 377 89.0 4.8e-18
XP_016874782 (OMIM: 109800,114480,137215,163200,19 ( 227) 377 89.1 5.5e-18
NP_002515 (OMIM: 114500,137550,162900,163200,16479 ( 189) 373 88.2 8.6e-18
XP_005247285 (OMIM: 608435) PREDICTED: ras-related ( 208) 373 88.2 9.3e-18
NP_036351 (OMIM: 608435) ras-related protein M-Ras ( 208) 373 88.2 9.3e-18
XP_016861376 (OMIM: 608435) PREDICTED: ras-related ( 208) 373 88.2 9.3e-18
NP_001078518 (OMIM: 608435) ras-related protein M- ( 208) 373 88.2 9.3e-18
NP_001239019 (OMIM: 608435) ras-related protein M- ( 208) 373 88.2 9.3e-18
NP_002921 (OMIM: 609592) GTP-binding protein Rit2 ( 217) 373 88.2 9.6e-18
NP_005334 (OMIM: 109800,137550,162900,163200,18847 ( 189) 371 87.7 1.1e-17
NP_001123914 (OMIM: 109800,137550,162900,163200,18 ( 189) 371 87.7 1.1e-17
XP_005263786 (OMIM: 179551) PREDICTED: ras-related ( 206) 358 85.0 8.2e-17
XP_005263784 (OMIM: 179551) PREDICTED: ras-related ( 206) 358 85.0 8.2e-17
NP_002872 (OMIM: 179551) ras-related protein Ral-B ( 206) 358 85.0 8.2e-17
XP_016860111 (OMIM: 179551) PREDICTED: ras-related ( 206) 358 85.0 8.2e-17
XP_005263785 (OMIM: 179551) PREDICTED: ras-related ( 206) 358 85.0 8.2e-17
XP_005263781 (OMIM: 179551) PREDICTED: ras-related ( 228) 358 85.1 8.8e-17
XP_016860110 (OMIM: 179551) PREDICTED: ras-related ( 228) 358 85.1 8.8e-17
XP_011509875 (OMIM: 179551) PREDICTED: ras-related ( 229) 358 85.1 8.9e-17
NP_789765 (OMIM: 109800,137550,162900,163200,18847 ( 170) 352 83.7 1.7e-16
NP_008843 (OMIM: 609591,615355) GTP-binding protei ( 219) 348 83.0 3.7e-16
NP_001243750 (OMIM: 609591,615355) GTP-binding pro ( 236) 348 83.0 3.9e-16
XP_005247286 (OMIM: 608435) PREDICTED: ras-related ( 170) 333 79.7 2.7e-15
NP_055814 (OMIM: 612398) ras-related protein Rab-2 ( 225) 331 79.4 4.5e-15
NP_071894 (OMIM: 602206) ras-related protein Rab-1 ( 212) 324 77.9 1.2e-14
>>NP_005605 (OMIM: 601293) GTP-binding protein Rheb [Hom (184 aa)
initn: 1162 init1: 1162 opt: 1162 Z-score: 1336.0 bits: 253.8 E(85289): 1.1e-67
Smith-Waterman score: 1162; 100.0% identity (100.0% similar) in 184 aa overlap (1-184:1-184)
10 20 30 40 50 60
pF1KB6 MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGKSS
130 140 150 160 170 180
pF1KB6 CSVM
::::
NP_005 CSVM
>>XP_011514759 (OMIM: 601293) PREDICTED: GTP-binding pro (173 aa)
initn: 1058 init1: 1058 opt: 1064 Z-score: 1225.2 bits: 233.2 E(85289): 1.7e-61
Smith-Waterman score: 1064; 97.1% identity (98.8% similar) in 173 aa overlap (12-184:1-173)
10 20 30 40 50 60
pF1KB6 MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD
.: ..:::::::::::::::::::::::::::::::::::::::::::
XP_011 MGTFNLGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD
10 20 30 40
70 80 90 100 110 120
pF1KB6 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 KDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGKSS
110 120 130 140 150 160
pF1KB6 CSVM
::::
XP_011 CSVM
170
>>NP_002877 (OMIM: 179541) ras-related protein Rap-2b [H (183 aa)
initn: 417 init1: 417 opt: 441 Z-score: 517.8 bits: 102.4 E(85289): 4.2e-22
Smith-Waterman score: 441; 41.3% identity (74.9% similar) in 179 aa overlap (5-181:2-176)
10 20 30 40 50 60
pF1KB6 MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD
. :...:: .::::.::.::: :.:...::::::. . : : :... :...:
NP_002 MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK
::: .... . . : . .:.:::::... .::. :: .. ... . ..:..:::::
NP_002 TAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNK
60 70 80 90 100 110
130 140 150 160 170
pF1KB6 KDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVD-VFRRIILEAEKMDGAAS-QGK
::. :: .:: ::::::: :. :.:.::: :...:: .: .:. ..:. ::. .:
NP_002 VDLEGEREVSYGEGKALAEEWSCPFMETSAK-NKASVDELFAEIV---RQMNYAAQPNGD
120 130 140 150 160 170
180
pF1KB6 SSCSVM
.:
NP_002 EGCCSACVIL
180
>>NP_056461 (OMIM: 179530) ras-related protein Rap-1b is (184 aa)
initn: 399 init1: 380 opt: 441 Z-score: 517.8 bits: 102.4 E(85289): 4.2e-22
Smith-Waterman score: 441; 38.0% identity (74.5% similar) in 184 aa overlap (5-184:2-184)
10 20 30 40 50 60
pF1KB6 MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD
. :...:: .::::.::.:::.: ::..::::::... : . :..:. :...:
NP_056 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK
::: .... . . : . .:. ::::.:. ..:. .. .. ..: . ..:..:::::
NP_056 TAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNK
60 70 80 90 100 110
130 140 150 160 170
pF1KB6 KDLHMERVISYEEGKALAESWNA-AFLESSAKENQTAVDVFRRIILEAEK---MDGAASQ
::. :::.. :.:. ::..:: :::::::: . .. ..: .. . .. . : : .
NP_056 CDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARK
120 130 140 150 160 170
180
pF1KB6 GKSSCSVM
::::...
NP_056 -KSSCQLL
180
>>NP_001010942 (OMIM: 179530) ras-related protein Rap-1b (184 aa)
initn: 399 init1: 380 opt: 441 Z-score: 517.8 bits: 102.4 E(85289): 4.2e-22
Smith-Waterman score: 441; 38.0% identity (74.5% similar) in 184 aa overlap (5-184:2-184)
10 20 30 40 50 60
pF1KB6 MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD
. :...:: .::::.::.:::.: ::..::::::... : . :..:. :...:
NP_001 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK
::: .... . . : . .:. ::::.:. ..:. .. .. ..: . ..:..:::::
NP_001 TAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNK
60 70 80 90 100 110
130 140 150 160 170
pF1KB6 KDLHMERVISYEEGKALAESWNA-AFLESSAKENQTAVDVFRRIILEAEK---MDGAASQ
::. :::.. :.:. ::..:: :::::::: . .. ..: .. . .. . : : .
NP_001 CDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARK
120 130 140 150 160 170
180
pF1KB6 GKSSCSVM
::::...
NP_001 -KSSCQLL
180
>>NP_066361 (OMIM: 179540) ras-related protein Rap-2a pr (183 aa)
initn: 408 init1: 408 opt: 430 Z-score: 505.3 bits: 100.1 E(85289): 2.1e-21
Smith-Waterman score: 430; 40.3% identity (72.9% similar) in 181 aa overlap (5-182:2-178)
10 20 30 40 50 60
pF1KB6 MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD
. :...:: .::::.::.::: : :...::::::. . : : :... :...:
NP_066 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK
::: .... . . : . .:.:::::... .::. :: .. ... . ..:..:::::
NP_066 TAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNK
60 70 80 90 100 110
130 140 150 160 170
pF1KB6 KDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVD-VFRRIILEAEKMDGAASQGKS
::. :: .: ::.:::: :. :.:.::: ..: :: .: .:. ..:. ::. :.
NP_066 VDLESEREVSSSEGRALAEEWGCPFMETSAK-SKTMVDELFAEIV---RQMNYAAQPDKD
120 130 140 150 160 170
180
pF1KB6 S--CSVM
. ::
NP_066 DPCCSACNIQ
180
>>XP_016857452 (OMIM: 179520) PREDICTED: ras-related pro (184 aa)
initn: 395 init1: 358 opt: 426 Z-score: 500.7 bits: 99.3 E(85289): 3.8e-21
Smith-Waterman score: 426; 36.6% identity (73.2% similar) in 183 aa overlap (5-184:2-184)
10 20 30 40 50 60
pF1KB6 MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD
. :...:: .::::.::.:::.: ::..::::::... : . :. :. :...:
XP_016 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK
::: .... . . : . .:. ::::.:. ..:. .. .. ..: . ..:..:::::
XP_016 TAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNK
60 70 80 90 100 110
130 140 150 160 170
pF1KB6 KDLHMERVISYEEGKALAESW-NAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQG--
::. :::.. :.:. ::..: : :::::::: . .. ..: .. . .. . ..
XP_016 CDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPK
120 130 140 150 160 170
180
pF1KB6 KSSCSVM
:.:: ..
XP_016 KKSCLLL
180
>>XP_016857451 (OMIM: 179520) PREDICTED: ras-related pro (184 aa)
initn: 395 init1: 358 opt: 426 Z-score: 500.7 bits: 99.3 E(85289): 3.8e-21
Smith-Waterman score: 426; 36.6% identity (73.2% similar) in 183 aa overlap (5-184:2-184)
10 20 30 40 50 60
pF1KB6 MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD
. :...:: .::::.::.:::.: ::..::::::... : . :. :. :...:
XP_016 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK
::: .... . . : . .:. ::::.:. ..:. .. .. ..: . ..:..:::::
XP_016 TAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNK
60 70 80 90 100 110
130 140 150 160 170
pF1KB6 KDLHMERVISYEEGKALAESW-NAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQG--
::. :::.. :.:. ::..: : :::::::: . .. ..: .. . .. . ..
XP_016 CDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPK
120 130 140 150 160 170
180
pF1KB6 KSSCSVM
:.:: ..
XP_016 KKSCLLL
180
>>XP_016857453 (OMIM: 179520) PREDICTED: ras-related pro (184 aa)
initn: 395 init1: 358 opt: 426 Z-score: 500.7 bits: 99.3 E(85289): 3.8e-21
Smith-Waterman score: 426; 36.6% identity (73.2% similar) in 183 aa overlap (5-184:2-184)
10 20 30 40 50 60
pF1KB6 MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD
. :...:: .::::.::.:::.: ::..::::::... : . :. :. :...:
XP_016 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK
::: .... . . : . .:. ::::.:. ..:. .. .. ..: . ..:..:::::
XP_016 TAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNK
60 70 80 90 100 110
130 140 150 160 170
pF1KB6 KDLHMERVISYEEGKALAESW-NAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQG--
::. :::.. :.:. ::..: : :::::::: . .. ..: .. . .. . ..
XP_016 CDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPK
120 130 140 150 160 170
180
pF1KB6 KSSCSVM
:.:: ..
XP_016 KKSCLLL
180
>>NP_002875 (OMIM: 179520) ras-related protein Rap-1A pr (184 aa)
initn: 395 init1: 358 opt: 426 Z-score: 500.7 bits: 99.3 E(85289): 3.8e-21
Smith-Waterman score: 426; 36.6% identity (73.2% similar) in 183 aa overlap (5-184:2-184)
10 20 30 40 50 60
pF1KB6 MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVD
. :...:: .::::.::.:::.: ::..::::::... : . :. :. :...:
NP_002 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK
::: .... . . : . .:. ::::.:. ..:. .. .. ..: . ..:..:::::
NP_002 TAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNK
60 70 80 90 100 110
130 140 150 160 170
pF1KB6 KDLHMERVISYEEGKALAESW-NAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQG--
::. :::.. :.:. ::..: : :::::::: . .. ..: .. . .. . ..
NP_002 CDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPK
120 130 140 150 160 170
180
pF1KB6 KSSCSVM
:.:: ..
NP_002 KKSCLLL
180
184 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 13:52:21 2016 done: Fri Nov 4 13:52:22 2016
Total Scan time: 4.740 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]