Result of FASTA (omim) for
pFN21AB6802
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6802, 184 aa
1>>>pF1KB6802 184 - 184 aa - 184 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7647+/-0.00035; mu= 10.1852+/- 0.022
mean_var=75.3574+/-14.894, 0's: 0 Z-trim(114.9): 150 B-trim: 66 in 1/52
Lambda= 0.147744
statistics sampled from 24895 (25061) to 24895 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.294), width: 16
Scan time: 5.230
The best scores are: opt bits E(85289)
NP_064570 (OMIM: 616778) dual specificity protein ( 184) 1250 275.5 3.3e-74
NP_001273484 (OMIM: 616778) dual specificity prote ( 205) 1146 253.4 1.7e-67
XP_016866551 (OMIM: 616778) PREDICTED: dual specif ( 124) 830 185.9 2.1e-47
XP_011513059 (OMIM: 616778) PREDICTED: dual specif ( 145) 726 163.8 1.1e-40
NP_542178 (OMIM: 616776) dual specificity protein ( 235) 686 155.3 6.4e-38
NP_001307407 (OMIM: 616776) dual specificity prote ( 232) 643 146.2 3.6e-35
XP_016883146 (OMIM: 616776) PREDICTED: dual specif ( 298) 615 140.3 2.8e-33
XP_016883145 (OMIM: 616776) PREDICTED: dual specif ( 311) 615 140.3 2.9e-33
XP_016883143 (OMIM: 616776) PREDICTED: dual specif ( 335) 615 140.3 3.1e-33
NP_001307408 (OMIM: 616776) dual specificity prote ( 295) 572 131.1 1.6e-30
XP_016883144 (OMIM: 616776) PREDICTED: dual specif ( 332) 572 131.1 1.8e-30
NP_001937 (OMIM: 602748,615269) dual specificity p ( 381) 320 77.4 2.9e-14
NP_001386 (OMIM: 300134) dual specificity protein ( 384) 320 77.4 3e-14
NP_001305432 (OMIM: 300134) dual specificity prote ( 384) 320 77.4 3e-14
XP_011529426 (OMIM: 300134) PREDICTED: dual specif ( 384) 320 77.4 3e-14
NP_009138 (OMIM: 608867) dual specificity protein ( 482) 321 77.7 3.1e-14
XP_011529425 (OMIM: 300134) PREDICTED: dual specif ( 415) 320 77.5 3.2e-14
NP_001938 (OMIM: 602749) dual specificity protein ( 419) 312 75.7 1e-13
XP_011535410 (OMIM: 615814) PREDICTED: serine/thre ( 199) 307 74.5 1.2e-13
NP_001124173 (OMIM: 615814) serine/threonine/tyros ( 223) 307 74.5 1.3e-13
NP_660294 (OMIM: 615814) serine/threonine/tyrosine ( 223) 307 74.5 1.3e-13
XP_016873431 (OMIM: 606780) PREDICTED: protein pho ( 559) 304 74.1 4.3e-13
NP_060327 (OMIM: 606780) protein phosphatase Sling ( 659) 304 74.1 5e-13
XP_011518234 (OMIM: 602038) PREDICTED: dual specif ( 625) 299 73.1 1e-12
NP_004411 (OMIM: 602038) dual specificity protein ( 625) 299 73.1 1e-12
XP_011518235 (OMIM: 602038) PREDICTED: dual specif ( 625) 299 73.1 1e-12
NP_004410 (OMIM: 603069) dual specificity protein ( 384) 289 70.8 2.9e-12
NP_001154802 (OMIM: 606778) protein phosphatase Sl ( 692) 286 70.3 7.4e-12
NP_001154803 (OMIM: 606778) protein phosphatase Sl ( 703) 286 70.3 7.5e-12
XP_016874981 (OMIM: 606778) PREDICTED: protein pho ( 923) 286 70.4 9.5e-12
XP_011536803 (OMIM: 606778) PREDICTED: protein pho ( 969) 286 70.4 9.9e-12
XP_011536802 (OMIM: 606778) PREDICTED: protein pho ( 969) 286 70.4 9.9e-12
XP_005269042 (OMIM: 606778) PREDICTED: protein pho ( 969) 286 70.4 9.9e-12
XP_016874980 (OMIM: 606778) PREDICTED: protein pho (1033) 286 70.4 1e-11
XP_005269041 (OMIM: 606778) PREDICTED: protein pho (1049) 286 70.4 1.1e-11
NP_061857 (OMIM: 606778) protein phosphatase Sling (1049) 286 70.4 1.1e-11
XP_011536799 (OMIM: 606778) PREDICTED: protein pho (1060) 286 70.4 1.1e-11
NP_085143 (OMIM: 607175) dual specificity protein ( 665) 283 69.7 1.1e-11
XP_011519158 (OMIM: 607175) PREDICTED: dual specif ( 665) 283 69.7 1.1e-11
XP_011519159 (OMIM: 607175) PREDICTED: dual specif ( 665) 283 69.7 1.1e-11
XP_006719218 (OMIM: 607175) PREDICTED: dual specif ( 665) 283 69.7 1.1e-11
XP_016884117 (OMIM: 611446) PREDICTED: dual specif ( 188) 275 67.7 1.2e-11
NP_001291724 (OMIM: 611446) dual specificity prote ( 188) 275 67.7 1.2e-11
NP_001291723 (OMIM: 611446) dual specificity prote ( 188) 275 67.7 1.2e-11
XP_011528223 (OMIM: 611446) PREDICTED: dual specif ( 188) 275 67.7 1.2e-11
XP_011528222 (OMIM: 611446) PREDICTED: dual specif ( 188) 275 67.7 1.2e-11
NP_689724 (OMIM: 611446) dual specificity protein ( 188) 275 67.7 1.2e-11
XP_005261425 (OMIM: 611446) PREDICTED: dual specif ( 188) 275 67.7 1.2e-11
XP_016884116 (OMIM: 611446) PREDICTED: dual specif ( 188) 275 67.7 1.2e-11
XP_006724211 (OMIM: 611446) PREDICTED: dual specif ( 188) 275 67.7 1.2e-11
>>NP_064570 (OMIM: 616778) dual specificity protein phos (184 aa)
initn: 1250 init1: 1250 opt: 1250 Z-score: 1453.1 bits: 275.5 E(85289): 3.3e-74
Smith-Waterman score: 1250; 100.0% identity (100.0% similar) in 184 aa overlap (1-184:1-184)
10 20 30 40 50 60
pF1KB6 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILAAPGILKFWAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILAAPGILKFWAF
130 140 150 160 170 180
pF1KB6 LRRL
::::
NP_064 LRRL
>>NP_001273484 (OMIM: 616778) dual specificity protein p (205 aa)
initn: 1146 init1: 1146 opt: 1146 Z-score: 1332.6 bits: 253.4 E(85289): 1.7e-67
Smith-Waterman score: 1146; 100.0% identity (100.0% similar) in 169 aa overlap (1-169:1-169)
10 20 30 40 50 60
pF1KB6 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILAAPGILKFWAF
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILGKYKEQGRTEP
130 140 150 160 170 180
pF1KB6 LRRL
NP_001 QPGARRWSSFPALAPLTYDNYTTET
190 200
>>XP_016866551 (OMIM: 616778) PREDICTED: dual specificit (124 aa)
initn: 830 init1: 830 opt: 830 Z-score: 971.9 bits: 185.9 E(85289): 2.1e-47
Smith-Waterman score: 830; 100.0% identity (100.0% similar) in 121 aa overlap (64-184:4-124)
40 50 60 70 80 90
pF1KB6 ILSVHDSARPMLEGVKYLCIPAADSPSQNLTRHFKESIKFIHECRLRGESCLVHCLAGVS
::::::::::::::::::::::::::::::
XP_016 MKRTRHFKESIKFIHECRLRGESCLVHCLAGVS
10 20 30
100 110 120 130 140 150
pF1KB6 RSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEE
40 50 60 70 80 90
160 170 180
pF1KB6 YGESPLQDAEEAKNILAAPGILKFWAFLRRL
:::::::::::::::::::::::::::::::
XP_016 YGESPLQDAEEAKNILAAPGILKFWAFLRRL
100 110 120
>>XP_011513059 (OMIM: 616778) PREDICTED: dual specificit (145 aa)
initn: 726 init1: 726 opt: 726 Z-score: 851.1 bits: 163.8 E(85289): 1.1e-40
Smith-Waterman score: 726; 100.0% identity (100.0% similar) in 106 aa overlap (64-169:4-109)
40 50 60 70 80 90
pF1KB6 ILSVHDSARPMLEGVKYLCIPAADSPSQNLTRHFKESIKFIHECRLRGESCLVHCLAGVS
::::::::::::::::::::::::::::::
XP_011 MKRTRHFKESIKFIHECRLRGESCLVHCLAGVS
10 20 30
100 110 120 130 140 150
pF1KB6 RSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEE
40 50 60 70 80 90
160 170 180
pF1KB6 YGESPLQDAEEAKNILAAPGILKFWAFLRRL
::::::::::::::::
XP_011 YGESPLQDAEEAKNILGKYKEQGRTEPQPGARRWSSFPALAPLTYDNYTTET
100 110 120 130 140
>>NP_542178 (OMIM: 616776) dual specificity protein phos (235 aa)
initn: 706 init1: 686 opt: 686 Z-score: 801.8 bits: 155.3 E(85289): 6.4e-38
Smith-Waterman score: 686; 55.0% identity (82.2% similar) in 169 aa overlap (1-169:1-169)
10 20 30 40 50 60
pF1KB6 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS
:::::.:.:::::.::: ::.: .::..::.:::.:.:.: .:.:. . :: ::.::.:
NP_542 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA
. .:::: :.::: ::: : .:::::.::.:::.:.: ::.:::: .::.:.:....:
NP_542 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILAAPGILKFWAF
: :::: ::..::.:: .. :. :.:..::::..: :: . .:
NP_542 TRPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGSA
130 140 150 160 170 180
pF1KB6 LRRL
NP_542 TSASSAGPHSAASEGTVQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
190 200 210 220 230
>>NP_001307407 (OMIM: 616776) dual specificity protein p (232 aa)
initn: 659 init1: 639 opt: 643 Z-score: 752.4 bits: 146.2 E(85289): 3.6e-35
Smith-Waterman score: 643; 53.7% identity (81.5% similar) in 162 aa overlap (8-169:5-166)
10 20 30 40 50 60
pF1KB6 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS
.:::::.::: ::.: .::..::.:::.:.:.: .:.:. . :: ::.::.:
NP_001 MTEGVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA
. .:::: :.::: ::: : .:::::.::.:::.:.: ::.:::: .::.:.:....:
NP_001 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILAAPGILKFWAF
: :::: ::..::.:: .. :. :.:..::::..: :: . .:
NP_001 TRPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGSA
120 130 140 150 160 170
pF1KB6 LRRL
NP_001 TSASSAGPHSAASEGTVQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
180 190 200 210 220 230
>>XP_016883146 (OMIM: 616776) PREDICTED: dual specificit (298 aa)
initn: 615 init1: 615 opt: 615 Z-score: 718.4 bits: 140.3 E(85289): 2.8e-33
Smith-Waterman score: 615; 59.4% identity (85.5% similar) in 138 aa overlap (1-138:1-138)
10 20 30 40 50 60
pF1KB6 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS
:::::.:.:::::.::: ::.: .::..::.:::.:.:.: .:.:. . :: ::.::.:
XP_016 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA
. .:::: :.::: ::: : .:::::.::.:::.:.: ::.:::: .::.:.:....:
XP_016 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILAAPGILKFWAF
: :::: ::..::.::
XP_016 TRPIANPNPGFRQQLEEFGWASSQKGARHRTSKTSGAQCPPMTSATCLLAARVALLSAAL
130 140 150 160 170 180
>>XP_016883145 (OMIM: 616776) PREDICTED: dual specificit (311 aa)
initn: 615 init1: 615 opt: 615 Z-score: 718.2 bits: 140.3 E(85289): 2.9e-33
Smith-Waterman score: 615; 59.4% identity (85.5% similar) in 138 aa overlap (1-138:1-138)
10 20 30 40 50 60
pF1KB6 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS
:::::.:.:::::.::: ::.: .::..::.:::.:.:.: .:.:. . :: ::.::.:
XP_016 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA
. .:::: :.::: ::: : .:::::.::.:::.:.: ::.:::: .::.:.:....:
XP_016 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILAAPGILKFWAF
: :::: ::..::.::
XP_016 TRPIANPNPGFRQQLEEFGWASSQKDGSGFATEDEDKEWPHRLAQQGSLLPPILLQALWL
130 140 150 160 170 180
>>XP_016883143 (OMIM: 616776) PREDICTED: dual specificit (335 aa)
initn: 615 init1: 615 opt: 615 Z-score: 717.7 bits: 140.3 E(85289): 3.1e-33
Smith-Waterman score: 615; 59.4% identity (85.5% similar) in 138 aa overlap (1-138:1-138)
10 20 30 40 50 60
pF1KB6 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS
:::::.:.:::::.::: ::.: .::..::.:::.:.:.: .:.:. . :: ::.::.:
XP_016 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA
. .:::: :.::: ::: : .:::::.::.:::.:.: ::.:::: .::.:.:....:
XP_016 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILAAPGILKFWAF
: :::: ::..::.::
XP_016 TRPIANPNPGFRQQLEEFGWASSQKDGSGFATEDEDKEWPHRLAQQGSLLPPILLQALWL
130 140 150 160 170 180
>>NP_001307408 (OMIM: 616776) dual specificity protein p (295 aa)
initn: 572 init1: 572 opt: 572 Z-score: 669.0 bits: 131.1 E(85289): 1.6e-30
Smith-Waterman score: 572; 58.0% identity (84.7% similar) in 131 aa overlap (8-138:5-135)
10 20 30 40 50 60
pF1KB6 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS
.:::::.::: ::.: .::..::.:::.:.:.: .:.:. . :: ::.::.:
NP_001 MTEGVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA
. .:::: :.::: ::: : .:::::.::.:::.:.: ::.:::: .::.:.:....:
NP_001 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILAAPGILKFWAF
: :::: ::..::.::
NP_001 TRPIANPNPGFRQQLEEFGWASSQKGARHRTSKTSGAQCPPMTSATCLLAARVALLSAAL
120 130 140 150 160 170
184 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 15:06:45 2016 done: Fri Nov 4 15:06:46 2016
Total Scan time: 5.230 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]