Result of FASTA (ccds) for
pFN21AB6474
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6474, 355 aa
1>>>pF1KB6474 355 - 355 aa - 355 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7509+/-0.000978; mu= 13.3340+/- 0.059
mean_var=60.4250+/-11.994, 0's: 0 Z-trim(103.7): 24 B-trim: 0 in 0/48
Lambda= 0.164993
statistics sampled from 7521 (7531) to 7521 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.606), E-opt: 0.2 (0.231), width: 16
Scan time: 2.670
The best scores are: opt bits E(32554)
CCDS5638.1 PON1 gene_id:5444|Hs108|chr7 ( 355) 2353 568.8 2.5e-162
CCDS5640.1 PON2 gene_id:5445|Hs108|chr7 ( 354) 1634 397.6 8.2e-111
CCDS5639.1 PON3 gene_id:5446|Hs108|chr7 ( 354) 1497 365.0 5.4e-101
CCDS47644.1 PON2 gene_id:5445|Hs108|chr7 ( 342) 1101 270.7 1.2e-72
>>CCDS5638.1 PON1 gene_id:5444|Hs108|chr7 (355 aa)
initn: 2353 init1: 2353 opt: 2353 Z-score: 3027.8 bits: 568.8 E(32554): 2.5e-162
Smith-Waterman score: 2353; 100.0% identity (100.0% similar) in 355 aa overlap (1-355:1-355)
10 20 30 40 50 60
pF1KB6 MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 GLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 TDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 TDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 TNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 TNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPP
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 ASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 ASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL
310 320 330 340 350
>>CCDS5640.1 PON2 gene_id:5445|Hs108|chr7 (354 aa)
initn: 1642 init1: 1258 opt: 1634 Z-score: 2102.9 bits: 397.6 E(32554): 8.2e-111
Smith-Waterman score: 1634; 65.9% identity (89.0% similar) in 355 aa overlap (1-355:1-354)
10 20 30 40 50 60
pF1KB6 MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPN
:..:.:. :::..:::. .. . ..::.: :::. :.::.:.:.::::.::::..::::
CCDS56 MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTF
::::.: :::.::..:: :..:: ::.:::.:: : . :: :. ::..::::::::::
CCDS56 GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRIS-RGFDLASFNPHGISTF
70 80 90 100 110
130 140 150 160 170 180
pF1KB6 TDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYG
:.:...::.:::::. :.:::.:::.: :.:::::::..:.:::..:::.:::: :::.
CCDS56 IDNDDTVYLFVVNHPEFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYA
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 TNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAEL
:::::: ::.:. : ::.: :. ::::::.::.::::::: ::::::::: ::.:.:..
CCDS56 TNDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADI
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 LAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPP
:::.::: :::.: .:: :: :...:::::.:.:: .::.::::::::.:.: :: .:::
CCDS56 LAHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPP
240 250 260 270 280 290
310 320 330 340 350
pF1KB6 ASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL
.::::::::::.:.: :: :::.::.:::::.::::: :::::::..:.::::::
CCDS56 SSEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL
300 310 320 330 340 350
>>CCDS5639.1 PON3 gene_id:5446|Hs108|chr7 (354 aa)
initn: 1488 init1: 1102 opt: 1497 Z-score: 1926.6 bits: 365.0 E(32554): 5.4e-101
Smith-Waterman score: 1497; 60.8% identity (85.6% similar) in 355 aa overlap (1-355:1-354)
10 20 30 40 50 60
pF1KB6 MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPN
:.::.::.:::.::.: . ... :.:: :::.::: ::.:.. .:.::::..:::.
CCDS56 MGKLVALVLLGVGLSLVGEMFLAFRERVNASREVEPVEPENCHLIEELESGSEDIDILPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTF
:::::::::::::. .: :. ::::.::::::..: . : :.:. :: ::::::: :
CCDS56 GLAFISSGLKYPGMPNFAPDEPGKIFLMDLNEQNPRAQALEISGG-FDKELFNPHGISIF
70 80 90 100 110
130 140 150 160 170 180
pF1KB6 TDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYG
:.::..:: ::::: :::::.:::.:...::..::::.:.:: ..::::..:::.::.
CCDS56 IDKDNTVYLYVVNHPHMKSTVEIFKFEEQQRSLVYLKTIKHELLKSVNDIVVLGPEQFYA
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 TNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAEL
: :::: . :. .:: : : :.::..::: ::.:::.:: ::::..: : ::::.:..
CCDS56 TRDHYFTNSLLSFFEMILDLRWTYVLFYSPREVKVVAKGFCSANGITVSADQKYVYVADV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 LAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPP
:..::..::: :: :: :: ....:::::..::: :::. .::::: ::.. :. :.::
CCDS56 AAKNIHIMEKHDNWDLTQLKVIQLGTLVDNLTVDPATGDILAGCHPNPMKLLNYNPEDPP
240 250 260 270 280 290
310 320 330 340 350
pF1KB6 ASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL
.::::::::.:.:.:.:. :::.::.::::..:::::.::.::::::::.:::::
CCDS56 GSEVLRIQNVLSEKPRVSTVYANNGSVLQGTSVASVYHGKILIGTVFHKTLYCEL
300 310 320 330 340 350
>>CCDS47644.1 PON2 gene_id:5445|Hs108|chr7 (342 aa)
initn: 1569 init1: 1101 opt: 1101 Z-score: 1417.5 bits: 270.7 E(32554): 1.2e-72
Smith-Waterman score: 1538; 63.7% identity (85.6% similar) in 355 aa overlap (1-355:1-342)
10 20 30 40 50 60
pF1KB6 MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPN
:..:.:. :::..:::. .. . ..::.: :::. :.::.:.:.::::.::::..::::
CCDS47 MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTF
::::.: :::.::..:: :..:: ::.:::.:: : . :: :. ::..::::::::::
CCDS47 GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRIS-RGFDLASFNPHGISTF
70 80 90 100 110
130 140 150 160 170 180
pF1KB6 TDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYG
:.. :.:::.:::.: :.:::::::..:.:::..:::.:::: :::.
CCDS47 IDNE------------FKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYA
120 130 140 150 160
190 200 210 220 230 240
pF1KB6 TNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAEL
:::::: ::.:. : ::.: :. ::::::.::.::::::: ::::::::: ::.:.:..
CCDS47 TNDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADI
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB6 LAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPP
:::.::: :::.: .:: :: :...:::::.:.:: .::.::::::::.:.: :: .:::
CCDS47 LAHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPP
230 240 250 260 270 280
310 320 330 340 350
pF1KB6 ASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL
.::::::::::.:.: :: :::.::.:::::.::::: :::::::..:.::::::
CCDS47 SSEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL
290 300 310 320 330 340
355 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:31:46 2016 done: Fri Nov 4 16:31:46 2016
Total Scan time: 2.670 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]