FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6448, 349 aa
  1>>>pF1KB6448 349 - 349 aa - 349 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6039+/-0.00082; mu= 15.0369+/- 0.049
 mean_var=68.6856+/-13.858, 0's: 0 Z-trim(107.5): 23  B-trim: 0 in 0/51
 Lambda= 0.154754
 statistics sampled from 9590 (9607) to 9590 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.295), width:  16
 Scan time:  2.420

The best scores are:                                      opt bits E(32554)
CCDS7498.1 HIF1AN gene_id:55662|Hs108|chr10        ( 349) 2427 550.7 6.8e-157
CCDS3017.1 HSPBAP1 gene_id:79663|Hs108|chr3        ( 488)  325 81.4 1.7e-15
CCDS10627.1 KDM8 gene_id:79831|Hs108|chr16         ( 416)  302 76.3 5.2e-14
CCDS45448.1 KDM8 gene_id:79831|Hs108|chr16         ( 454)  302 76.3 5.6e-14


>>CCDS7498.1 HIF1AN gene_id:55662|Hs108|chr10             (349 aa)
 initn: 2427 init1: 2427 opt: 2427  Z-score: 2930.2  bits: 550.7 E(32554): 6.8e-157
Smith-Waterman score: 2427; 100.0% identity (100.0% similar) in 349 aa overlap (1-349:1-349)

               10        20        30        40        50        60
pF1KB6 MAATAAEAVASGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 MAATAAEAVASGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 PVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 PVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 EEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 EEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 QLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 QLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 QVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 QVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGA
              250       260       270       280       290       300

              310       320       330       340         
pF1KB6 PTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN
       :::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 PTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN
              310       320       330       340         

>>CCDS3017.1 HSPBAP1 gene_id:79663|Hs108|chr3             (488 aa)
 initn: 282 init1: 160 opt: 325  Z-score: 391.7  bits: 81.4 E(32554): 1.7e-15
Smith-Waterman score: 329; 27.0% identity (55.3% similar) in 300 aa overlap (51-341:32-309)

               30        40        50         60        70         
pF1KB6 GALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIEN-EEPVVLTDTNLVYPALKWDLE
                                     .:.:.: . ..:... .  . .:: .:. .
CCDS30 AAGSEATTPVIVAAGAGGEEGEHVKPFKPEKAKEIIMSLQQPAIFCNMVFDWPARHWNAK
              10        20        30        40        50        60 

      80        90       100       110       120       130         
pF1KB6 YLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNREEMKFHEFVEKLQDIQQRG
       ::..        :  ..  .:  .  :.:..  .:.   :  :  ..::.    : .. .
CCDS30 YLSQ--------VLHGKQIRF-RMGMKSMSTVPQFETTCNYVEATLEEFLTWNCDQSSIS
                      70         80        90       100       110  

     140       150       160             170       180       190   
pF1KB6 GEERLYLQQTLNDTVGRKIVMDF------LGFNWNWINKQQGKRGWGQLTSNLLLIGMEG
       :  : : .. .   .  :  ...      :  . .: .     :. :: ..  : ::  :
CCDS30 GPFRDYDHSKFWAYADYKYFVSLFEDKTDLFQDVKWSDFGFPGRN-GQEST--LWIGSLG
            120       130       140       150        160           

           200        210       220       230        240       250 
pF1KB6 NVTPAHYDEQQ-NFFAQIKGYKRCILFPPDQFECLYPYPV-HHPCDRQSQVDFDNPDYER
         :: : :    :.  :..: ::  ::::..   :::  . ..  .  :...  ::: .:
CCDS30 AHTPCHLDSYGCNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKR
     170       180       190       200       210       220         

             260       270       280       290       300       310 
pF1KB6 FPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGAPTPKRIEYPLK
       ::.:...  . ....::.::..: .:::..::.    .:...: : .       .:    
CCDS30 FPQFRKAQRHAVTLSPGQVLFVPRHWWHYVESI--DPVTVSINSWIE-------LEEDHL
     230       240       250       260         270              280

             320       330       340                               
pF1KB6 AHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN                      
       :. . :: : .   :  :  :::..   ::                              
CCDS30 ARVEEAITRMLVCALKTAE-NPQNTRAWLNPTEVEETSHAVNCCYLNAAVSAFFDRCRTS
              290        300       310       320       330         

>>CCDS10627.1 KDM8 gene_id:79831|Hs108|chr16              (416 aa)
 initn: 333 init1: 165 opt: 302  Z-score: 365.0  bits: 76.3 E(32554): 5.2e-14
Smith-Waterman score: 335; 28.2% identity (56.1% similar) in 262 aa overlap (40-297:182-415)

      10        20        30        40        50          60       
pF1KB6 ASGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRA--EELIENEEPVVLTDT
                                     . .::: . . .   :...   .::.:  .
CCDS10 KRPARGSLPEQPCTKKARADHGLIPDVKLEKTVPRLHRPSLQHFREQFLVPGRPVILKGV
             160       170       180       190       200       210 

        70         80        90       100       110       120      
pF1KB6 NLVYPAL-KWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNREEMKFH
          .: . ::.:::.::  :     :  .:     : ::.            ..  :  .
CCDS10 ADHWPCMQKWSLEYIQEIAGCRTVPVEVGSR----YTDEEW-----------SQTLMTVN
             220       230       240                      250      

        130       140        150       160       170       180     
pF1KB6 EFVEKLQDIQQRGGEERLYL-QQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWGQLTSN
       ::. :    . :   .  :: :. : : .  .. .:.   ..  ..  . .    ..: :
CCDS10 EFISKYIVNEPR---DVGYLAQHQLFDQIP-ELKQDISIPDYCSLGDGEEE----EITIN
        260          270       280        290       300            

         190       200       210       220       230       240     
pF1KB6 LLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQSQVDFD
         . : .:...: : : ::::..:. : :   :. :..   :::. .:      :::: .
CCDS10 AWF-GPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHL-LHNTSQVDVE
      310        320       330       340       350        360      

         250       260       270       280       290       300     
pF1KB6 NPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGAPTPKR
       ::: :.::.: ..     ...::..:.::. .::....:    ....:.::.        
CCDS10 NPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRAL---DLSFSVSFWWS       
        370       380       390       400          410             

         310       320       330       340         
pF1KB6 IEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN

>>CCDS45448.1 KDM8 gene_id:79831|Hs108|chr16              (454 aa)
 initn: 333 init1: 165 opt: 302  Z-score: 364.4  bits: 76.3 E(32554): 5.6e-14
Smith-Waterman score: 335; 28.2% identity (56.1% similar) in 262 aa overlap (40-297:220-453)

      10        20        30        40        50          60       
pF1KB6 ASGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRA--EELIENEEPVVLTDT
                                     . .::: . . .   :...   .::.:  .
CCDS45 KRPARGSLPEQPCTKKARADHGLIPDVKLEKTVPRLHRPSLQHFREQFLVPGRPVILKGV
     190       200       210       220       230       240         

        70         80        90       100       110       120      
pF1KB6 NLVYPAL-KWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNREEMKFH
          .: . ::.:::.::  :     :  .:     : ::.            ..  :  .
CCDS45 ADHWPCMQKWSLEYIQEIAGCRTVPVEVGSR----YTDEEW-----------SQTLMTVN
     250       260       270       280                      290    

        130       140        150       160       170       180     
pF1KB6 EFVEKLQDIQQRGGEERLYL-QQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWGQLTSN
       ::. :    . :   .  :: :. : : .  .. .:.   ..  ..  . .    ..: :
CCDS45 EFISKYIVNEPR---DVGYLAQHQLFDQIP-ELKQDISIPDYCSLGDGEEE----EITIN
          300          310       320        330       340          

         190       200       210       220       230       240     
pF1KB6 LLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQSQVDFD
         . : .:...: : : ::::..:. : :   :. :..   :::. .:      :::: .
CCDS45 AWF-GPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHL-LHNTSQVDVE
         350       360       370       380       390        400    

         250       260       270       280       290       300     
pF1KB6 NPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGAPTPKR
       ::: :.::.: ..     ...::..:.::. .::....:    ....:.::.        
CCDS45 NPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRAL---DLSFSVSFWWS       
          410       420       430       440          450           

         310       320       330       340         
pF1KB6 IEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN




349 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 17:32:57 2016 done: Fri Nov  4 17:32:57 2016
 Total Scan time:  2.420 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]