Result of FASTA (omim) for
pFN21AB6592
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6592, 406 aa
1>>>pF1KB6592 406 - 406 aa - 406 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9166+/-0.000513; mu= 14.0855+/- 0.032
mean_var=79.4739+/-16.579, 0's: 0 Z-trim(108.0): 77 B-trim: 381 in 1/50
Lambda= 0.143867
statistics sampled from 15976 (16022) to 15976 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.535), E-opt: 0.2 (0.188), width: 16
Scan time: 8.400
The best scores are: opt bits E(85289)
NP_057213 (OMIM: 616008) COP9 signalosome complex ( 406) 2594 548.7 9.5e-156
NP_001317656 (OMIM: 616008) COP9 signalosome compl ( 420) 2305 488.7 1.1e-137
NP_001244935 (OMIM: 616008) COP9 signalosome compl ( 352) 2139 454.2 2.3e-127
>>NP_057213 (OMIM: 616008) COP9 signalosome complex subu (406 aa)
initn: 2594 init1: 2594 opt: 2594 Z-score: 2917.1 bits: 548.7 E(85289): 9.5e-156
Smith-Waterman score: 2594; 100.0% identity (100.0% similar) in 406 aa overlap (1-406:1-406)
10 20 30 40 50 60
pF1KB6 MAAAVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MAAAVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ISRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLASIYEKEEDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ISRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLASIYEKEEDW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 RNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 RNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 QRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSIL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 DRAVIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 DRAVIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVH
310 320 330 340 350 360
370 380 390 400
pF1KB6 FETREALPTWDKQIQSLCFQVNNLLEKISQTAPEWTAQAMEAQMAQ
::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FETREALPTWDKQIQSLCFQVNNLLEKISQTAPEWTAQAMEAQMAQ
370 380 390 400
>>NP_001317656 (OMIM: 616008) COP9 signalosome complex s (420 aa)
initn: 2305 init1: 2305 opt: 2305 Z-score: 2592.7 bits: 488.7 E(85289): 1.1e-137
Smith-Waterman score: 2305; 100.0% identity (100.0% similar) in 363 aa overlap (1-363:1-363)
10 20 30 40 50 60
pF1KB6 MAAAVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ISRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLASIYEKEEDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLASIYEKEEDW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 RNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 QRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSIL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 DRAVIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRAVIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVH
310 320 330 340 350 360
370 380 390 400
pF1KB6 FETREALPTWDKQIQSLCFQVNNLLEKISQTAPEWTAQAMEAQMAQ
:::
NP_001 FETSGNHQSIFCLWIYLVWIVHINGIIQYVTCDLLADSTQHSIFRVHPCHGSTRSPANVG
370 380 390 400 410 420
>>NP_001244935 (OMIM: 616008) COP9 signalosome complex s (352 aa)
initn: 2128 init1: 2128 opt: 2139 Z-score: 2407.7 bits: 454.2 E(85289): 2.3e-127
Smith-Waterman score: 2139; 96.0% identity (97.7% similar) in 354 aa overlap (1-354:1-352)
10 20 30 40 50 60
pF1KB6 MAAAVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ISRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLASIYEKEEDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLASIYEKEEDW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 RNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 QRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSIL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 DRAVIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVH
:::::::::::::::::::::::::::::::::: :: .. :. : : :...
NP_001 DRAVIEHNLLSASKLYNNITFEELGALLEIPAAKHEKPCQRGIS--RSNHFVSK
310 320 330 340 350
370 380 390 400
pF1KB6 FETREALPTWDKQIQSLCFQVNNLLEKISQTAPEWTAQAMEAQMAQ
406 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 20:41:50 2016 done: Sat Nov 5 20:41:51 2016
Total Scan time: 8.400 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]