Result of FASTA (ccds) for
pFN21AB8146
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8146, 373 aa
1>>>pF1KB8146 373 - 373 aa - 373 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6112+/-0.000829; mu= 15.2875+/- 0.050
mean_var=71.7126+/-14.411, 0's: 0 Z-trim(107.8): 31 B-trim: 549 in 1/48
Lambda= 0.151453
statistics sampled from 9762 (9790) to 9762 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.301), width: 16
Scan time: 2.510
The best scores are: opt bits E(32554)
CCDS30659.1 MECR gene_id:51102|Hs108|chr1 ( 373) 2472 549.2 2.2e-156
CCDS30660.1 MECR gene_id:51102|Hs108|chr1 ( 297) 1948 434.6 5.2e-122
CCDS11451.1 VAT1 gene_id:10493|Hs108|chr17 ( 393) 331 81.4 1.5e-15
CCDS665.1 CRYZ gene_id:1429|Hs108|chr1 ( 329) 274 68.9 7.3e-12
CCDS32492.1 VAT1L gene_id:57687|Hs108|chr16 ( 419) 269 67.9 1.9e-11
CCDS44162.1 CRYZ gene_id:1429|Hs108|chr1 ( 295) 264 66.7 3e-11
>>CCDS30659.1 MECR gene_id:51102|Hs108|chr1 (373 aa)
initn: 2472 init1: 2472 opt: 2472 Z-score: 2921.2 bits: 549.2 E(32554): 2.2e-156
Smith-Waterman score: 2472; 99.7% identity (100.0% similar) in 373 aa overlap (1-373:1-373)
10 20 30 40 50 60
pF1KB8 MWVCSTLWRVRTPARQWRGLLPASGCHGPAASSYSASAEPARVRALVYGHHGDPAKVVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 MWVCSTLWRVRTPARQWRGLLPASGCHGPAASSYSASAEPARVRALVYGHHGDPAKVVEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGLLPELPAVGGNEGVAQVVAVGSNVT
:::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::
CCDS30 KNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 GLKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 GLKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 LQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASVSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 ELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASVSLL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 IFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACSQVPLQDYQSALEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 IFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACSQVPLQDYQSALEAS
310 320 330 340 350 360
370
pF1KB8 MKPFISSKQILTM
:::::::::::::
CCDS30 MKPFISSKQILTM
370
>>CCDS30660.1 MECR gene_id:51102|Hs108|chr1 (297 aa)
initn: 1948 init1: 1948 opt: 1948 Z-score: 2303.9 bits: 434.6 E(32554): 5.2e-122
Smith-Waterman score: 1948; 99.7% identity (100.0% similar) in 297 aa overlap (77-373:1-297)
50 60 70 80 90 100
pF1KB8 VYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGLLPELPAVGGN
:::::::::::::::::::.::::::::::
CCDS30 MLAAPINPSDINMIQGNYGFLPELPAVGGN
10 20 30
110 120 130 140 150 160
pF1KB8 EGVAQVVAVGSNVTGLKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 EGVAQVVAVGSNVTGLKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGV
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB8 NPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 NPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSD
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB8 RLKSLGAEHVITEEELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 RLKSLGAEHVITEEELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYG
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB8 GMAKQPVVASVSLLIFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 GMAKQPVVASVSLLIFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACS
220 230 240 250 260 270
350 360 370
pF1KB8 QVPLQDYQSALEASMKPFISSKQILTM
:::::::::::::::::::::::::::
CCDS30 QVPLQDYQSALEASMKPFISSKQILTM
280 290
>>CCDS11451.1 VAT1 gene_id:10493|Hs108|chr17 (393 aa)
initn: 287 init1: 130 opt: 331 Z-score: 392.6 bits: 81.4 E(32554): 1.5e-15
Smith-Waterman score: 331; 32.2% identity (58.2% similar) in 273 aa overlap (23-286:26-286)
10 20 30 40 50
pF1KB8 MWVCSTLWRVRTPARQWRGLLPASGCHGPAAS--SYSASAEPARVRALVYGHHGDPA
:: . :::: . .:.: : .: :: :
CCDS11 MSDEREVAEAATGEDASSPPPKTEAASDPQHPAASEGAAAAAASPPLLRCLVLTGFGGYD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 KVVELKNLELA--AVRGSDVRVKMLAAPINPSDINMIQGNYGLLPELPAVGGNEGVAQVV
:: .:.. : : ... ... : .: .:. :: : :: ::.. : ::.. :.
CCDS11 KV-KLQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVI
70 80 90 100 110
120 130 140 150 160 170
pF1KB8 AVGSNVTGLKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYR
::: .:. : :: :. : . : :. :.. . .: . .. ::.: :: :::
CCDS11 AVGEGVSDRKAGDRVMVLNRS-GMWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYM
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 MLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTI-NV-VRDRPDIQKLSDRLKSL
.:.:: .:::: ::. . . .:::.:..:. ::. :: : . .: . ::
CCDS11 VLFDFGNLQPGHSVLVHMAAGGVGMAAVQLC-----RTVENVTVFGTASASK-HEALKEN
180 190 200 210 220 230
240 250 260 270 280
pF1KB8 GAEHVITEEELRRPEMKNFFKDMPQPR---LALNCVGGKSSTELLRQLARGGTMVTYGGM
:. : : . . .. . .: . .:. .... .::..... : : .::::
CCDS11 GVTHPI---DYHTTDYVDEIKKI-SPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMA
240 250 260 270 280
290 300 310 320 330 340
pF1KB8 AKQPVVASVSLLIFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACSQV
CCDS11 NLLTGPKRNLMALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLAL
290 300 310 320 330 340
>>CCDS665.1 CRYZ gene_id:1429|Hs108|chr1 (329 aa)
initn: 274 init1: 231 opt: 274 Z-score: 326.5 bits: 68.9 E(32554): 7.3e-12
Smith-Waterman score: 284; 23.3% identity (59.0% similar) in 317 aa overlap (43-358:8-313)
20 30 40 50 60 70
pF1KB8 PARQWRGLLPASGCHGPAASSYSASAEPARVRALVYGHHGDPAKVVELK-NLELAAVRGS
.::. . : : .:..:. .. . .
CCDS66 MATGQKLMRAVRVFEFGGP-EVLKLRSDIAVPIPKDH
10 20 30
80 90 100 110 120 130
pF1KB8 DVRVKMLAAPINPSDINMIQGNYGLLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPA
.: .:. : .:: . . .:.:. : :: . :.. .. . :::.:....: :: :. .
CCDS66 QVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTS
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB8 NAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNA
.. : . :. ..... ..: . ....:..:. :::: :. .. :.::. ..
CCDS66 STISGGYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHG
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB8 SNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNFF
...::: :. ::: : ::. .... . ::. :.. ::..:....:. . . .
CCDS66 ASGGVGLAACQIARAYGLKILGTA-GTEEGQKIV--LQN-GAHEVFNHREVNYIDKIKKY
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB8 KDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASVSLLIFKDLKLRGFW
. .. ... . .. : :..:: ... : .. . . . :. .. :
CCDS66 VGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVG--SRGTIEINPRDTMAKESSIIGVT
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB8 LSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACSQVPLQDYQSALEASMKPFISSKQIL
: . :. .:.. .: .. : : :: ::. : :
CCDS66 LFSSTKE----EFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMI
280 290 300 310 320
pF1KB8 TM
CCDS66 LLL
>>CCDS32492.1 VAT1L gene_id:57687|Hs108|chr16 (419 aa)
initn: 131 init1: 107 opt: 269 Z-score: 319.0 bits: 67.9 E(32554): 1.9e-11
Smith-Waterman score: 269; 25.7% identity (56.7% similar) in 268 aa overlap (19-286:21-276)
10 20 30 40 50
pF1KB8 MWVCSTLWRVRTPARQWRGLLPASGCHGPAASSYSASAEPARVRALVYGHHGDPAKVV
: :: : : .. . . : .::.: . : :.
CCDS32 MAKEGVEKAEETEQMIEKEAGKEPAEGGGGDGSHRLGDAQE---MRAVVLAGFGGLNKLR
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 ELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGLLPELPAVGGNEGVAQVVAVGSN
... . . ....... : .: :. . ::: :. : : : : . : :.:..
CCDS32 LFRK-AMPEPQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 VTGLKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDF
: : . :: :. : .. ..: . : . ..:.:. .. ::.. .: ::: ::..
CCDS32 VKGYEIGDRVM-AFVNYNAWAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYVMLFEV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 EQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVIT
.:. : ::. .....:::::: :. ... :. . . . ..: . : ...
CCDS32 ANLREGMSVLVHSAGGGVGQAVAQLCSTVPNVTVFGTASTFKHEAIKDSVTHLFDRNADY
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 EEELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASVS
.:..: .. :. .:.:. : .. . : : ::.. ::
CCDS32 VQEVKRISAEGV--DI-----VLDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETKSF
240 250 260 270 280
300 310 320 330 340 350
pF1KB8 LLIFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACSQVPLQDYQSALE
CCDS32 FSFAKSWWQVEKVNPIKLYEENKVIAGFSLLNLLFKQGRAGLIRGVVEKLIGLYNQKKIK
290 300 310 320 330 340
>>CCDS44162.1 CRYZ gene_id:1429|Hs108|chr1 (295 aa)
initn: 248 init1: 248 opt: 264 Z-score: 315.4 bits: 66.7 E(32554): 3e-11
Smith-Waterman score: 264; 27.4% identity (66.7% similar) in 201 aa overlap (43-242:8-203)
20 30 40 50 60 70
pF1KB8 PARQWRGLLPASGCHGPAASSYSASAEPARVRALVYGHHGDPAKVVELK-NLELAAVRGS
.::. . : : .:..:. .. . .
CCDS44 MATGQKLMRAVRVFEFGGP-EVLKLRSDIAVPIPKDH
10 20 30
80 90 100 110 120 130
pF1KB8 DVRVKMLAAPINPSDINMIQGNYGLLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPA
.: .:. : .:: . . .:.:. : :: . :.. .. . :::.:....: :: :. .
CCDS44 QVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTS
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB8 NAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNA
.. : . :. ..... ..: . ....:..:. :::: :. .. :.::. ..
CCDS44 STISGGYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHG
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB8 SNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNFF
...::: :. ::: : ::. .... . ::. :.. ::..:....:.
CCDS44 ASGGVGLAACQIARAYGLKILGTA-GTEEGQKIV--LQN-GAHEVFNHREVNYIDKIKVV
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB8 KDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASVSLLIFKDLKLRGFW
CCDS44 GSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLE
220 230 240 250 260 270
373 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 19:59:01 2016 done: Fri Nov 4 19:59:02 2016
Total Scan time: 2.510 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]