Result of FASTA (omim) for
pFN21AB9792
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9792, 210 aa
1>>>pF1KB9792 210 - 210 aa - 210 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1580+/-0.000338; mu= 6.7527+/- 0.021
mean_var=156.1088+/-30.962, 0's: 0 Z-trim(119.5): 73 B-trim: 243 in 1/55
Lambda= 0.102650
statistics sampled from 33432 (33509) to 33432 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.747), E-opt: 0.2 (0.393), width: 16
Scan time: 6.540
The best scores are: opt bits E(85289)
NP_937861 (OMIM: 275355,601566) inhibitor of growt ( 210) 1444 224.8 8.1e-59
NP_937860 (OMIM: 275355,601566) inhibitor of growt ( 235) 1444 224.8 8.8e-59
NP_001254657 (OMIM: 275355,601566) inhibitor of gr ( 262) 1444 224.9 9.5e-59
NP_937862 (OMIM: 275355,601566) inhibitor of growt ( 279) 1444 224.9 1e-58
NP_005528 (OMIM: 275355,601566) inhibitor of growt ( 422) 1444 225.1 1.3e-58
XP_011530229 (OMIM: 604215) PREDICTED: inhibitor o ( 225) 704 115.2 8.3e-26
NP_001278888 (OMIM: 604215) inhibitor of growth pr ( 240) 704 115.2 8.7e-26
NP_001555 (OMIM: 604215) inhibitor of growth prote ( 280) 704 115.3 9.7e-26
XP_005253755 (OMIM: 608524) PREDICTED: inhibitor o ( 200) 502 85.3 7.7e-17
XP_011519267 (OMIM: 608524) PREDICTED: inhibitor o ( 222) 502 85.3 8.3e-17
NP_001121057 (OMIM: 608524) inhibitor of growth pr ( 225) 502 85.3 8.4e-17
NP_001121054 (OMIM: 608524) inhibitor of growth pr ( 249) 502 85.3 9.1e-17
NP_001121055 (OMIM: 608524) inhibitor of growth pr ( 246) 428 74.4 1.8e-13
XP_016874882 (OMIM: 608524) PREDICTED: inhibitor o ( 196) 422 73.4 2.8e-13
XP_016874881 (OMIM: 608524) PREDICTED: inhibitor o ( 199) 422 73.4 2.8e-13
XP_011519266 (OMIM: 608524) PREDICTED: inhibitor o ( 224) 422 73.5 3.1e-13
NP_001121056 (OMIM: 608524) inhibitor of growth pr ( 245) 422 73.5 3.3e-13
NP_057246 (OMIM: 608524) inhibitor of growth prote ( 248) 422 73.5 3.3e-13
NP_115705 (OMIM: 608525) inhibitor of growth prote ( 240) 416 72.6 6e-13
XP_016860586 (OMIM: 608525) PREDICTED: inhibitor o ( 300) 416 72.7 7.1e-13
NP_061944 (OMIM: 607493) inhibitor of growth prote ( 418) 408 71.6 2.1e-12
NP_001317091 (OMIM: 608525) inhibitor of growth pr ( 226) 351 62.9 4.5e-10
XP_016860588 (OMIM: 608525) PREDICTED: inhibitor o ( 286) 351 63.0 5.4e-10
XP_016860587 (OMIM: 608525) PREDICTED: inhibitor o ( 286) 351 63.0 5.4e-10
>>NP_937861 (OMIM: 275355,601566) inhibitor of growth pr (210 aa)
initn: 1444 init1: 1444 opt: 1444 Z-score: 1177.0 bits: 224.8 E(85289): 8.1e-59
Smith-Waterman score: 1444; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:1-210)
10 20 30 40 50 60
pF1KB9 MLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 MLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 GADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 GADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 SKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 SKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKG
130 140 150 160 170 180
190 200 210
pF1KB9 KWYCPKCRGENEKTMDKALEKSKKERAYNR
::::::::::::::::::::::::::::::
NP_937 KWYCPKCRGENEKTMDKALEKSKKERAYNR
190 200 210
>>NP_937860 (OMIM: 275355,601566) inhibitor of growth pr (235 aa)
initn: 1444 init1: 1444 opt: 1444 Z-score: 1176.3 bits: 224.8 E(85289): 8.8e-59
Smith-Waterman score: 1444; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:26-235)
10 20 30
pF1KB9 MLHCVQRALIRSQELGDEKIQIVSQMVELVENRTR
:::::::::::::::::::::::::::::::::::
NP_937 MEILKELDECYERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 QVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 QVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASS
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB9 NHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 NHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMI
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB9 GCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 GCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
190 200 210 220 230
>>NP_001254657 (OMIM: 275355,601566) inhibitor of growth (262 aa)
initn: 1444 init1: 1444 opt: 1444 Z-score: 1175.7 bits: 224.9 E(85289): 9.5e-59
Smith-Waterman score: 1444; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:53-262)
10 20 30
pF1KB9 MLHCVQRALIRSQELGDEKIQIVSQMVELV
::::::::::::::::::::::::::::::
NP_001 GPSAITEILKELDECYERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELV
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB9 ENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENR
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB9 ENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVS
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB9 YGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
210 220 230 240 250 260
>>NP_937862 (OMIM: 275355,601566) inhibitor of growth pr (279 aa)
initn: 1444 init1: 1444 opt: 1444 Z-score: 1175.3 bits: 224.9 E(85289): 1e-58
Smith-Waterman score: 1444; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:70-279)
10 20 30
pF1KB9 MLHCVQRALIRSQELGDEKIQIVSQMVELV
::::::::::::::::::::::::::::::
NP_937 IDAKYQEILKELDECYERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELV
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB9 ENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 ENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENR
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB9 ENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 ENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVS
160 170 180 190 200 210
160 170 180 190 200 210
pF1KB9 YGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 YGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
220 230 240 250 260 270
>>NP_005528 (OMIM: 275355,601566) inhibitor of growth pr (422 aa)
initn: 1444 init1: 1444 opt: 1444 Z-score: 1173.0 bits: 225.1 E(85289): 1.3e-58
Smith-Waterman score: 1444; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:213-422)
10 20 30
pF1KB9 MLHCVQRALIRSQELGDEKIQIVSQMVELV
::::::::::::::::::::::::::::::
NP_005 RAWPWKQILKELDECYERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELV
190 200 210 220 230 240
40 50 60 70 80 90
pF1KB9 ENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENR
250 260 270 280 290 300
100 110 120 130 140 150
pF1KB9 ENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVS
310 320 330 340 350 360
160 170 180 190 200 210
pF1KB9 YGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
370 380 390 400 410 420
>>XP_011530229 (OMIM: 604215) PREDICTED: inhibitor of gr (225 aa)
initn: 836 init1: 662 opt: 704 Z-score: 584.3 bits: 115.2 E(85289): 8.3e-26
Smith-Waterman score: 849; 62.4% identity (81.7% similar) in 202 aa overlap (5-206:31-222)
10 20 30
pF1KB9 MLHCVQRALIRSQELGDEKIQIVSQMVELVENRT
.::::: ::::::::::::.::.::::::.
XP_011 MNETLKEIDDVYEKYKKEDDLNQKKRLQQLLQRALINSQELGDEKIQIVTQMLELVENRA
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 RQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENAS
::.. : . : :. ... : :: : ..: .. .:.: ::::..:.:.
XP_011 RQMELHSQCF---QDPAESERASDKAKMD------SSQPER-SSRRPRRQRTSESRDLCH
70 80 90 100 110
100 110 120 130 140 150
pF1KB9 SNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEM
. .: . :::::.:..::::::::: ::::::... :::::::::::::::::::
XP_011 MANGIEDCDDQPPKEKKSKSAKKKKRSKAKQEREASPVEFAIDPNEPTYCLCNQVSYGEM
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB9 IGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
:::::..:::::::::::.:..:::::::::::::.:::::::. ::.::.:
XP_011 IGCDNEQCPIEWFHFSCVSLTYKPKGKWYCPKCRGDNEKTMDKSTEKTKKDRRSR
180 190 200 210 220
>>NP_001278888 (OMIM: 604215) inhibitor of growth protei (240 aa)
initn: 836 init1: 662 opt: 704 Z-score: 583.9 bits: 115.2 E(85289): 8.7e-26
Smith-Waterman score: 849; 62.4% identity (81.7% similar) in 202 aa overlap (5-206:46-237)
10 20 30
pF1KB9 MLHCVQRALIRSQELGDEKIQIVSQMVELVENRT
.::::: ::::::::::::.::.::::::.
NP_001 APQTLKEIDDVYEKYKKEDDLNQKKRLQQLLQRALINSQELGDEKIQIVTQMLELVENRA
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB9 RQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENAS
::.. : . : :. ... : :: : ..: .. .:.: ::::..:.:.
NP_001 RQMELHSQCF---QDPAESERASDKAKMD------SSQPER-SSRRPRRQRTSESRDLCH
80 90 100 110 120
100 110 120 130 140 150
pF1KB9 SNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEM
. .: . :::::.:..::::::::: ::::::... :::::::::::::::::::
NP_001 MANGIEDCDDQPPKEKKSKSAKKKKRSKAKQEREASPVEFAIDPNEPTYCLCNQVSYGEM
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB9 IGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
:::::..:::::::::::.:..:::::::::::::.:::::::. ::.::.:
NP_001 IGCDNEQCPIEWFHFSCVSLTYKPKGKWYCPKCRGDNEKTMDKSTEKTKKDRRSR
190 200 210 220 230 240
>>NP_001555 (OMIM: 604215) inhibitor of growth protein 2 (280 aa)
initn: 836 init1: 662 opt: 704 Z-score: 583.1 bits: 115.3 E(85289): 9.7e-26
Smith-Waterman score: 849; 62.4% identity (81.7% similar) in 202 aa overlap (5-206:86-277)
10 20 30
pF1KB9 MLHCVQRALIRSQELGDEKIQIVSQMVELVENRT
.::::: ::::::::::::.::.::::::.
NP_001 YQETLKEIDDVYEKYKKEDDLNQKKRLQQLLQRALINSQELGDEKIQIVTQMLELVENRA
60 70 80 90 100 110
40 50 60 70 80 90
pF1KB9 RQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENAS
::.. : . : :. ... : :: : ..: .. .:.: ::::..:.:.
NP_001 RQMELHSQCF---QDPAESERASDKAKMD------SSQPER-SSRRPRRQRTSESRDLCH
120 130 140 150 160
100 110 120 130 140 150
pF1KB9 SNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEM
. .: . :::::.:..::::::::: ::::::... :::::::::::::::::::
NP_001 MANGIEDCDDQPPKEKKSKSAKKKKRSKAKQEREASPVEFAIDPNEPTYCLCNQVSYGEM
170 180 190 200 210 220
160 170 180 190 200 210
pF1KB9 IGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
:::::..:::::::::::.:..:::::::::::::.:::::::. ::.::.:
NP_001 IGCDNEQCPIEWFHFSCVSLTYKPKGKWYCPKCRGDNEKTMDKSTEKTKKDRRSR
230 240 250 260 270 280
>>XP_005253755 (OMIM: 608524) PREDICTED: inhibitor of gr (200 aa)
initn: 511 init1: 368 opt: 502 Z-score: 423.3 bits: 85.3 E(85289): 7.7e-17
Smith-Waterman score: 502; 38.5% identity (68.7% similar) in 195 aa overlap (1-193:15-199)
10 20 30 40
pF1KB9 MLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEA
.:. .:.: . .:.::.:.:.. : :.:... :..:. . :::
XP_005 MSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 QQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGT
.: . .:. .. ::. ....: :.. : :.. ..: :.. ..
XP_005 --DLKEKQIESSDYDSSSSKGKKKGRTQKE--KKAARARSK------GKNSDEEAPKTAQ
70 80 90 100 110
110 120 130 140 150 160
pF1KB9 PKEKKAKTSKKKKRSKAK--AEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPI
: : ..:: . .. . . .. :.:.::::::::::.:::::::::::: .: :
XP_005 KKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSI
120 130 140 150 160 170
170 180 190 200 210
pF1KB9 EWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
:::::.::::. ::.:::.::.: : .:
XP_005 EWFHFACVGLTTKPRGKWFCPRCSQERKKK
180 190 200
>>XP_011519267 (OMIM: 608524) PREDICTED: inhibitor of gr (222 aa)
initn: 511 init1: 368 opt: 502 Z-score: 422.7 bits: 85.3 E(85289): 8.3e-17
Smith-Waterman score: 502; 38.5% identity (68.7% similar) in 195 aa overlap (1-193:37-221)
10 20 30
pF1KB9 MLHCVQRALIRSQELGDEKIQIVSQMVELV
.:. .:.: . .:.::.:.:.. : :.:
XP_011 RTEDLKAEIDKLATEYMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMV
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 ENRTRQVDSHVELFEAQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENR
... :..:. . ::: .: . .:. .. ::. ....: :.. : :..
XP_011 DKHIRRLDTDLARFEA--DLKEKQIESSDYDSSSSKGKKKGRTQKE--KKAARARSK---
70 80 90 100 110
100 110 120 130 140
pF1KB9 ENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAK--AEREASPADLPIDPNEPTYCLCNQ
..: :.. .. : : ..:: . .. . . .. :.:.::::::::::.:
XP_011 ---GKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQ
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB9 VSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAY
::::::::::: .: ::::::.::::. ::.:::.::.: : .:
XP_011 VSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQERKKK
180 190 200 210 220
210
pF1KB9 NR
210 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:03:47 2016 done: Fri Nov 4 20:03:47 2016
Total Scan time: 6.540 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]