Result of FASTA (omim) for
pFN21AB7575
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7575, 216 aa
1>>>pF1KB7575 216 - 216 aa - 216 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1020+/-0.000356; mu= 10.9778+/- 0.022
mean_var=98.6142+/-20.101, 0's: 0 Z-trim(115.6): 112 B-trim: 420 in 2/51
Lambda= 0.129153
statistics sampled from 26116 (26239) to 26116 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.308), width: 16
Scan time: 6.620
The best scores are: opt bits E(85289)
NP_001193668 (OMIM: 605494) centromere protein R i ( 216) 1384 267.8 9.9e-72
NP_055103 (OMIM: 605494) centromere protein R isof ( 177) 1097 214.2 1.1e-55
XP_016856344 (OMIM: 605494) PREDICTED: centromere ( 211) 1036 202.9 3.2e-52
XP_006710578 (OMIM: 605494) PREDICTED: centromere ( 295) 1004 197.1 2.6e-50
XP_016856343 (OMIM: 605494) PREDICTED: centromere ( 223) 1002 196.6 2.7e-50
XP_006710577 (OMIM: 605494) PREDICTED: centromere ( 303) 997 195.8 6.6e-50
XP_016856342 (OMIM: 605494) PREDICTED: centromere ( 308) 997 195.8 6.7e-50
XP_016856346 (OMIM: 605494) PREDICTED: centromere ( 185) 377 80.1 2.7e-15
XP_016856345 (OMIM: 605494) PREDICTED: centromere ( 189) 375 79.7 3.5e-15
XP_016856721 (OMIM: 616773) PREDICTED: mitoguardin ( 553) 194 46.3 0.00012
XP_016856720 (OMIM: 616773) PREDICTED: mitoguardin ( 585) 194 46.3 0.00012
XP_016865721 (OMIM: 613973) PREDICTED: cyclic GMP- ( 497) 191 45.7 0.00016
XP_016873709 (OMIM: 602355) PREDICTED: TNF recepto ( 324) 188 45.0 0.00017
NP_001254494 (OMIM: 123812) cAMP-responsive elemen ( 131) 180 43.3 0.00023
NP_001309432 (OMIM: 104221) alpha-1A adrenergic re ( 370) 185 44.5 0.00027
NP_001158312 (OMIM: 613311,615595) LYR motif-conta ( 130) 178 42.9 0.00029
XP_016880852 (OMIM: 614942) PREDICTED: CDP-diacylg ( 549) 184 44.5 0.00042
XP_011534200 (OMIM: 605196) PREDICTED: ubiquinone ( 329) 179 43.4 0.00053
XP_016884212 (OMIM: 604589) PREDICTED: bromodomain ( 643) 183 44.3 0.00054
XP_006715563 (OMIM: 605196) PREDICTED: ubiquinone ( 410) 179 43.4 0.00064
NP_001333021 (OMIM: 142680,191190,614810) tumor ne ( 302) 174 42.4 0.00095
NP_001275965 (OMIM: 616990) clusterin-like protein ( 518) 174 42.6 0.0015
XP_016882892 (OMIM: 608349) PREDICTED: hematopoiet ( 218) 168 41.2 0.0016
XP_016882891 (OMIM: 608349) PREDICTED: hematopoiet ( 225) 167 41.0 0.0019
NP_001243358 (OMIM: 605904) PDZ and LIM domain pro ( 136) 160 39.6 0.0031
NP_001264049 (OMIM: 616841) zinc finger protein 46 ( 127) 159 39.3 0.0033
XP_016870596 (OMIM: 602874) PREDICTED: ceramide gl ( 239) 162 40.1 0.0037
NP_001305856 (OMIM: 180480) ribulose-phosphate 3-e ( 225) 161 39.9 0.004
XP_016856700 (OMIM: 147522) PREDICTED: inositol-tr ( 730) 167 41.4 0.0047
XP_016875691 (OMIM: 615335) PREDICTED: ceramide sy ( 334) 162 40.2 0.0049
XP_006715517 (OMIM: 606457) PREDICTED: inhibitor o (1379) 170 42.1 0.0053
XP_006715516 (OMIM: 606457) PREDICTED: inhibitor o (1394) 170 42.1 0.0053
NP_001317999 (OMIM: 615335) ceramide synthase 5 is ( 392) 162 40.3 0.0055
NP_001186384 (OMIM: 601540) bromodomain-containing ( 836) 165 41.0 0.0068
NP_001287990 (OMIM: 605846) B-cell CLL/lymphoma 7 ( 213) 154 38.6 0.0096
>>NP_001193668 (OMIM: 605494) centromere protein R isofo (216 aa)
initn: 1384 init1: 1384 opt: 1384 Z-score: 1408.8 bits: 267.8 E(85289): 9.9e-72
Smith-Waterman score: 1384; 99.5% identity (99.5% similar) in 216 aa overlap (1-216:1-216)
10 20 30 40 50 60
pF1KB7 MPFAPVAQAGVQWHDFRSLQHLLPAFKRFSCLSLGSSWDYSVKRSLKLDGLLEENSFDPS
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPFAPVAQARVQWHDFRSLQHLLPAFKRFSCLSLGSSWDYSVKRSLKLDGLLEENSFDPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 KITRKKSVITYSPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KITRKKSVITYSPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 DNDEFMMLLSKVEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNDEFMMLLSKVEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKE
130 140 150 160 170 180
190 200 210
pF1KB7 LMTKVNKQKLFEKSTGLPHKASRHLDSYEFLKAILN
::::::::::::::::::::::::::::::::::::
NP_001 LMTKVNKQKLFEKSTGLPHKASRHLDSYEFLKAILN
190 200 210
>>NP_055103 (OMIM: 605494) centromere protein R isoform (177 aa)
initn: 1097 init1: 1097 opt: 1097 Z-score: 1121.0 bits: 214.2 E(85289): 1.1e-55
Smith-Waterman score: 1097; 100.0% identity (100.0% similar) in 175 aa overlap (42-216:3-177)
20 30 40 50 60 70
pF1KB7 QWHDFRSLQHLLPAFKRFSCLSLGSSWDYSVKRSLKLDGLLEENSFDPSKITRKKSVITY
::::::::::::::::::::::::::::::
NP_055 MPVKRSLKLDGLLEENSFDPSKITRKKSVITY
10 20 30
80 90 100 110 120 130
pF1KB7 SPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSK
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB7 VEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKLF
100 110 120 130 140 150
200 210
pF1KB7 EKSTGLPHKASRHLDSYEFLKAILN
:::::::::::::::::::::::::
NP_055 EKSTGLPHKASRHLDSYEFLKAILN
160 170
>>XP_016856344 (OMIM: 605494) PREDICTED: centromere prot (211 aa)
initn: 1039 init1: 1014 opt: 1036 Z-score: 1058.5 bits: 202.9 E(85289): 3.2e-52
Smith-Waterman score: 1036; 86.3% identity (90.4% similar) in 197 aa overlap (28-216:16-211)
10 20 30 40 50
pF1KB7 MPFAPVAQAGVQWHDFRSLQHLLPAFKRFSCLSL--------GSSWDYSVKRSLKLDGLL
:::::.. :: : ..:. .
XP_016 MFPPGRGGLDATSSARFSCLGVSFGGFSVFGSCWVRFIQRQWCFPES-
10 20 30 40
60 70 80 90 100 110
pF1KB7 EENSFDPSKITRKKSVITYSPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLT
.. :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNASFDPSKITRKKSVITYSPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLT
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 ESKESTTKDNDEFMMLLSKVEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESKESTTKDNDEFMMLLSKVEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLK
110 120 130 140 150 160
180 190 200 210
pF1KB7 REMQKTKELMTKVNKQKLFEKSTGLPHKASRHLDSYEFLKAILN
::::::::::::::::::::::::::::::::::::::::::::
XP_016 REMQKTKELMTKVNKQKLFEKSTGLPHKASRHLDSYEFLKAILN
170 180 190 200 210
>>XP_006710578 (OMIM: 605494) PREDICTED: centromere prot (295 aa)
initn: 997 init1: 997 opt: 1004 Z-score: 1024.2 bits: 197.1 E(85289): 2.6e-50
Smith-Waterman score: 1004; 95.3% identity (97.0% similar) in 169 aa overlap (42-210:125-293)
20 30 40 50 60 70
pF1KB7 QWHDFRSLQHLLPAFKRFSCLSLGSSWDYSVKRSLKLDGLLEENSFDPSKITRKKSVITY
::::::::::::::::::::::::::::::
XP_006 AFPLADFLFSEVAGFVLFSGSGAFPNLRMPVKRSLKLDGLLEENSFDPSKITRKKSVITY
100 110 120 130 140 150
80 90 100 110 120 130
pF1KB7 SPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSK
160 170 180 190 200 210
140 150 160 170 180 190
pF1KB7 VEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKLF
220 230 240 250 260 270
200 210
pF1KB7 EKSTGLPHKASRHLDSYEFLKAILN
::::::::: . : . .:
XP_006 EKSTGLPHKDTSILKALRFEV
280 290
>>XP_016856343 (OMIM: 605494) PREDICTED: centromere prot (223 aa)
initn: 1002 init1: 1002 opt: 1002 Z-score: 1023.9 bits: 196.6 E(85289): 2.7e-50
Smith-Waterman score: 1002; 100.0% identity (100.0% similar) in 160 aa overlap (41-200:39-198)
20 30 40 50 60 70
pF1KB7 VQWHDFRSLQHLLPAFKRFSCLSLGSSWDYSVKRSLKLDGLLEENSFDPSKITRKKSVIT
::::::::::::::::::::::::::::::
XP_016 IFCFRKLLGSFYSAAVVLSRISECRRYLLPSVKRSLKLDGLLEENSFDPSKITRKKSVIT
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB7 YSPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLS
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB7 KVEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKL
130 140 150 160 170 180
200 210
pF1KB7 FEKSTGLPHKASRHLDSYEFLKAILN
::::::::::
XP_016 FEKSTGLPHKGIKADLPITRFSQRTEFLHRGDCYH
190 200 210 220
>>XP_006710577 (OMIM: 605494) PREDICTED: centromere prot (303 aa)
initn: 997 init1: 997 opt: 997 Z-score: 1017.0 bits: 195.8 E(85289): 6.6e-50
Smith-Waterman score: 997; 100.0% identity (100.0% similar) in 159 aa overlap (42-200:125-283)
20 30 40 50 60 70
pF1KB7 QWHDFRSLQHLLPAFKRFSCLSLGSSWDYSVKRSLKLDGLLEENSFDPSKITRKKSVITY
::::::::::::::::::::::::::::::
XP_006 AFPLADFLFSEVAGFVLFSGSGAFPNLRMPVKRSLKLDGLLEENSFDPSKITRKKSVITY
100 110 120 130 140 150
80 90 100 110 120 130
pF1KB7 SPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSK
160 170 180 190 200 210
140 150 160 170 180 190
pF1KB7 VEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKLF
220 230 240 250 260 270
200 210
pF1KB7 EKSTGLPHKASRHLDSYEFLKAILN
:::::::::
XP_006 EKSTGLPHKGIKKKCTHHEHQLLHLPDHI
280 290 300
>>XP_016856342 (OMIM: 605494) PREDICTED: centromere prot (308 aa)
initn: 997 init1: 997 opt: 997 Z-score: 1016.9 bits: 195.8 E(85289): 6.7e-50
Smith-Waterman score: 997; 100.0% identity (100.0% similar) in 159 aa overlap (42-200:125-283)
20 30 40 50 60 70
pF1KB7 QWHDFRSLQHLLPAFKRFSCLSLGSSWDYSVKRSLKLDGLLEENSFDPSKITRKKSVITY
::::::::::::::::::::::::::::::
XP_016 AFPLADFLFSEVAGFVLFSGSGAFPNLRMPVKRSLKLDGLLEENSFDPSKITRKKSVITY
100 110 120 130 140 150
80 90 100 110 120 130
pF1KB7 SPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSK
160 170 180 190 200 210
140 150 160 170 180 190
pF1KB7 VEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKLF
220 230 240 250 260 270
200 210
pF1KB7 EKSTGLPHKASRHLDSYEFLKAILN
:::::::::
XP_016 EKSTGLPHKGIKADLPITRFSQRTEFLHRGDCYH
280 290 300
>>XP_016856346 (OMIM: 605494) PREDICTED: centromere prot (185 aa)
initn: 377 init1: 377 opt: 377 Z-score: 395.7 bits: 80.1 E(85289): 2.7e-15
Smith-Waterman score: 377; 98.3% identity (100.0% similar) in 60 aa overlap (42-101:125-184)
20 30 40 50 60 70
pF1KB7 QWHDFRSLQHLLPAFKRFSCLSLGSSWDYSVKRSLKLDGLLEENSFDPSKITRKKSVITY
::::::::::::::::::::::::::::::
XP_016 AFPLADFLFSEVAGFVLFSGSGAFPNLRMPVKRSLKLDGLLEENSFDPSKITRKKSVITY
100 110 120 130 140 150
80 90 100 110 120 130
pF1KB7 SPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSK
:::::::::::::::::::::::::::::.
XP_016 SPTTGTCQMSLFASPTSSEEQKHRNGLSNDS
160 170 180
>>XP_016856345 (OMIM: 605494) PREDICTED: centromere prot (189 aa)
initn: 375 init1: 375 opt: 375 Z-score: 393.6 bits: 79.7 E(85289): 3.5e-15
Smith-Waterman score: 375; 100.0% identity (100.0% similar) in 59 aa overlap (42-100:125-183)
20 30 40 50 60 70
pF1KB7 QWHDFRSLQHLLPAFKRFSCLSLGSSWDYSVKRSLKLDGLLEENSFDPSKITRKKSVITY
::::::::::::::::::::::::::::::
XP_016 AFPLADFLFSEVAGFVLFSGSGAFPNLRMPVKRSLKLDGLLEENSFDPSKITRKKSVITY
100 110 120 130 140 150
80 90 100 110 120 130
pF1KB7 SPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSK
:::::::::::::::::::::::::::::
XP_016 SPTTGTCQMSLFASPTSSEEQKHRNGLSNGLCWKP
160 170 180
>>XP_016856721 (OMIM: 616773) PREDICTED: mitoguardin-1 i (553 aa)
initn: 194 init1: 194 opt: 194 Z-score: 204.7 bits: 46.3 E(85289): 0.00012
Smith-Waterman score: 194; 80.0% identity (85.7% similar) in 35 aa overlap (6-40:495-529)
10 20 30
pF1KB7 MPFAPVAQAGVQWHDFRSLQHLLPAFKRFSCLSLG
::::::::::. ::: : : :::: ::::.
XP_016 NSSFKETAVASSCWSVLKQKRQQMKTESHSVAQAGVQWHDLSSLQPLPPRFKRFFCLSLS
470 480 490 500 510 520
40 50 60 70 80 90
pF1KB7 SSWDYSVKRSLKLDGLLEENSFDPSKITRKKSVITYSPTTGTCQMSLFASPTSSEEQKHR
:::::
XP_016 SSWDYRRLPPCPANLYIFGKDGVSSCWPG
530 540 550
216 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 01:35:07 2016 done: Sat Nov 5 01:35:08 2016
Total Scan time: 6.620 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]