Result of FASTA (omim) for
pFN21AA1508
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1508, 1126 aa
1>>>pF1KA1508 1126 - 1126 aa - 1126 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.1351+/-0.000452; mu= -5.0400+/- 0.028
mean_var=376.0856+/-75.872, 0's: 0 Z-trim(121.3): 369 B-trim: 0 in 0/57
Lambda= 0.066135
statistics sampled from 37346 (37759) to 37346 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.443), width: 16
Scan time: 13.710
The best scores are: opt bits E(85289)
XP_006722054 (OMIM: 610590) PREDICTED: rho GTPase- (1473) 7636 744.0 1.6e-213
XP_011523378 (OMIM: 610590) PREDICTED: rho GTPase- (1159) 7623 742.6 3.1e-213
NP_001186346 (OMIM: 610590) rho GTPase-activating (1491) 7623 742.7 3.7e-213
XP_011523375 (OMIM: 610590) PREDICTED: rho GTPase- (1476) 7616 742.1 5.9e-213
XP_016880391 (OMIM: 610590) PREDICTED: rho GTPase- (1119) 7404 721.7 5.9e-207
XP_006722056 (OMIM: 610590) PREDICTED: rho GTPase- (1249) 7405 721.9 6e-207
XP_011523379 (OMIM: 610590) PREDICTED: rho GTPase- (1117) 7400 721.3 7.6e-207
XP_011523376 (OMIM: 610590) PREDICTED: rho GTPase- (1397) 7069 689.9 2.9e-197
XP_011523377 (OMIM: 610590) PREDICTED: rho GTPase- (1285) 6332 619.5 4e-176
XP_006722055 (OMIM: 610590) PREDICTED: rho GTPase- (1408) 4735 467.2 3.2e-130
XP_016871950 (OMIM: 609870) PREDICTED: rho GTPase- (1948) 1339 143.3 1.4e-32
XP_016871949 (OMIM: 609870) PREDICTED: rho GTPase- (1948) 1339 143.3 1.4e-32
XP_005252601 (OMIM: 609870) PREDICTED: rho GTPase- (1948) 1339 143.3 1.4e-32
XP_005252599 (OMIM: 609870) PREDICTED: rho GTPase- (1958) 1339 143.3 1.4e-32
NP_065875 (OMIM: 609870) rho GTPase-activating pro (1958) 1339 143.3 1.4e-32
XP_016871948 (OMIM: 609870) PREDICTED: rho GTPase- (1958) 1339 143.3 1.4e-32
XP_011517908 (OMIM: 609870) PREDICTED: rho GTPase- (1924) 1303 139.8 1.5e-31
XP_011517907 (OMIM: 609870) PREDICTED: rho GTPase- (1982) 1303 139.8 1.5e-31
XP_011517906 (OMIM: 609870) PREDICTED: rho GTPase- (1992) 1303 139.8 1.5e-31
XP_011517904 (OMIM: 609870) PREDICTED: rho GTPase- (1992) 1303 139.8 1.5e-31
XP_011517905 (OMIM: 609870) PREDICTED: rho GTPase- (1992) 1303 139.8 1.5e-31
XP_011517909 (OMIM: 609870) PREDICTED: rho GTPase- (1491) 1224 132.2 2.3e-29
XP_011509785 (OMIM: 610578) PREDICTED: rho GTPase- ( 397) 539 66.3 4.1e-10
XP_016859989 (OMIM: 610578) PREDICTED: rho GTPase- ( 432) 539 66.4 4.4e-10
NP_060930 (OMIM: 610578) rho GTPase-activating pro ( 475) 539 66.4 4.7e-10
XP_016859988 (OMIM: 610578) PREDICTED: rho GTPase- ( 475) 539 66.4 4.7e-10
XP_011509781 (OMIM: 610578) PREDICTED: rho GTPase- ( 475) 539 66.4 4.7e-10
NP_954976 (OMIM: 610591) rho GTPase-activating pro ( 548) 472 60.1 4.4e-08
XP_011522776 (OMIM: 610591) PREDICTED: rho GTPase- ( 581) 472 60.1 4.6e-08
XP_005257185 (OMIM: 610591) PREDICTED: rho GTPase- ( 667) 472 60.1 5.1e-08
XP_016879801 (OMIM: 610591) PREDICTED: rho GTPase- ( 689) 472 60.1 5.2e-08
XP_011522774 (OMIM: 610591) PREDICTED: rho GTPase- ( 722) 472 60.2 5.4e-08
XP_011522773 (OMIM: 610591) PREDICTED: rho GTPase- ( 865) 472 60.2 6.1e-08
XP_006721810 (OMIM: 610591) PREDICTED: rho GTPase- ( 867) 472 60.2 6.1e-08
NP_001269219 (OMIM: 610591) rho GTPase-activating ( 889) 472 60.2 6.3e-08
XP_006721808 (OMIM: 610591) PREDICTED: rho GTPase- ( 889) 472 60.2 6.3e-08
XP_011522771 (OMIM: 610591) PREDICTED: rho GTPase- ( 900) 472 60.2 6.3e-08
XP_011522770 (OMIM: 610591) PREDICTED: rho GTPase- ( 922) 472 60.3 6.4e-08
XP_016879800 (OMIM: 610591) PREDICTED: rho GTPase- ( 922) 472 60.3 6.4e-08
XP_016872443 (OMIM: 610577) PREDICTED: rho GTPase- ( 742) 456 58.6 1.6e-07
NP_001257627 (OMIM: 610577) rho GTPase-activating ( 769) 456 58.7 1.6e-07
XP_011518063 (OMIM: 610577) PREDICTED: rho GTPase- ( 772) 456 58.7 1.6e-07
NP_001257628 (OMIM: 610577) rho GTPase-activating ( 794) 456 58.7 1.7e-07
XP_005252701 (OMIM: 610577) PREDICTED: rho GTPase- ( 794) 456 58.7 1.7e-07
NP_001257626 (OMIM: 610577) rho GTPase-activating ( 799) 456 58.7 1.7e-07
NP_001257625 (OMIM: 610577) rho GTPase-activating ( 816) 456 58.7 1.7e-07
NP_001257624 (OMIM: 610577) rho GTPase-activating ( 841) 456 58.7 1.7e-07
NP_060757 (OMIM: 610577) rho GTPase-activating pro ( 846) 456 58.7 1.7e-07
NP_001280010 (OMIM: 602857) beta-chimaerin isoform ( 261) 437 56.4 2.6e-07
NP_001193531 (OMIM: 118423,604356) N-chimaerin iso ( 334) 439 56.7 2.7e-07
>>XP_006722054 (OMIM: 610590) PREDICTED: rho GTPase-acti (1473 aa)
initn: 7636 init1: 7636 opt: 7636 Z-score: 3954.6 bits: 744.0 E(85289): 1.6e-213
Smith-Waterman score: 7636; 100.0% identity (100.0% similar) in 1120 aa overlap (1-1120:1-1120)
10 20 30 40 50 60
pF1KA1 MEQLPLGPRDGCSPRRPFPWQGPRTLLLYKSPQDGFGFTLRHFIVYPPESAVHCSLKEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEQLPLGPRDGCSPRRPFPWQGPRTLLLYKSPQDGFGFTLRHFIVYPPESAVHCSLKEEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 NGGRGGGPSPRYRLEPMDTIFVKNVKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGGRGGGPSPRYRLEPMDTIFVKNVKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 LIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTYAPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 ARASTRATMVPEPTSALPSDPRSPAAWSDPGLRVPPAARAHLDNSSLGMSQPRPSPGAFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ARASTRATMVPEPTSALPSDPRSPAAWSDPGLRVPPAARAHLDNSSLGMSQPRPSPGAFP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 HLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQVPRRAGERRCPAMAPRARSASQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQVPRRAGERRCPAMAPRARSASQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 RLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLSRATRSAEALGPGALVSPRFERC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLSRATRSAEALGPGALVSPRFERC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 GWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGYIGYRSYSPSFQRRTGLLHALSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGYIGYRSYSPSFQRRTGLLHALSF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 RDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTRALEPPAEDRGDEVVLRQKPPTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTRALEPPAEDRGDEVVLRQKPPTG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 RKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPLATTEDSLASIPFIDEPTSPSID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPLATTEDSLASIPFIDEPTSPSID
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 LQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRHYSQDCSSIKAGRRSSYLLAITT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRHYSQDCSSIKAGRRSSYLLAITT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 ERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSLDSWGTSEDADAPSKRHST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSLDSWGTSEDADAPSKRHST
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 SDLSDATFSDIRREGWLYYKQILTKKGKKAGSGLRQWKRVYAALRARSLSLSKERREPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDLSDATFSDIRREGWLYYKQILTKKGKKAGSGLRQWKRVYAALRARSLSLSKERREPGP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 AAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 WIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 KQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATENQR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 VPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDINLQDERWQDLNVIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDINLQDERWQDLNVIS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 SLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHYYETLKFLVGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHYYETLKFLVGH
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 LKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDWFFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDWFFS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120
pF1KA1 DEEDKGERTPVGDKEPQAVPNIEYLLPNIGRTVPPGDPGSADLLEI
::::::::::::::::::::::::::::::::::::::::
XP_006 DEEDKGERTPVGDKEPQAVPNIEYLLPNIGRTVPPGDPGSDSTTCSSAKSKGSWAPKKEP
1090 1100 1110 1120 1130 1140
XP_006 YAREMLAISFISAVNRKRKKRREARGLGSSTDDDSEQEAHKPGAGATAPGTQERPQGPLP
1150 1160 1170 1180 1190 1200
>>XP_011523378 (OMIM: 610590) PREDICTED: rho GTPase-acti (1159 aa)
initn: 7623 init1: 7623 opt: 7623 Z-score: 3949.3 bits: 742.6 E(85289): 3.1e-213
Smith-Waterman score: 7623; 100.0% identity (100.0% similar) in 1118 aa overlap (3-1120:21-1138)
10 20 30 40
pF1KA1 MEQLPLGPRDGCSPRRPFPWQGPRTLLLYKSPQDGFGFTLRH
::::::::::::::::::::::::::::::::::::::::
XP_011 MNGVAFCLVGIPPRPEPRPPQLPLGPRDGCSPRRPFPWQGPRTLLLYKSPQDGFGFTLRH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA1 FIVYPPESAVHCSLKEEENGGRGGGPSPRYRLEPMDTIFVKNVKEDGPAHRAGLRTGDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FIVYPPESAVHCSLKEEENGGRGGGPSPRYRLEPMDTIFVKNVKEDGPAHRAGLRTGDRL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 VKVNGESVIGKTYSQVIALIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNEPYSGEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKVNGESVIGKTYSQVIALIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNEPYSGEAR
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 SIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPRSPAAWSDPGLRVPPAARAHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPRSPAAWSDPGLRVPPAARAHL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA1 DNSSLGMSQPRPSPGAFPHLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQVPRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNSSLGMSQPRPSPGAFPHLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQVPRRA
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA1 GERRCPAMAPRARSASQDRLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLSRATR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GERRCPAMAPRARSASQDRLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLSRATR
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 SAEALGPGALVSPRFERCGWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGYIGYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAEALGPGALVSPRFERCGWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGYIGYR
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 SYSPSFQRRTGLLHALSFRDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTRALEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYSPSFQRRTGLLHALSFRDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTRALEP
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 PAEDRGDEVVLRQKPPTGRKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPLATTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAEDRGDEVVLRQKPPTGRKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPLATTE
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA1 DSLASIPFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRHYSQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSLASIPFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRHYSQD
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA1 CSSIKAGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSSIKAGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSL
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA1 DSWGTSEDADAPSKRHSTSDLSDATFSDIRREGWLYYKQILTKKGKKAGSGLRQWKRVYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSWGTSEDADAPSKRHSTSDLSDATFSDIRREGWLYYKQILTKKGKKAGSGLRQWKRVYA
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA1 ALRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTT
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA1 ADFCEYLFQAEDRDDMLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSSGPKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADFCEYLFQAEDRDDMLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSSGPKA
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA1 DSSPKGSRGLGGLKSEFLKQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSSPKGSRGLGGLKSEFLKQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAP
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA1 RAFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRG
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA1 PGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKL
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KA1 IRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMP
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KA1 DRYKIVETLIQHSDWFFSDEEDKGERTPVGDKEPQAVPNIEYLLPNIGRTVPPGDPGSAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRYKIVETLIQHSDWFFSDEEDKGERTPVGDKEPQAVPNIEYLLPNIGRTVPPGDPGSDS
1090 1100 1110 1120 1130 1140
pF1KA1 LLEI
XP_011 TTCSSAKSKLKKQRPEELL
1150
>>NP_001186346 (OMIM: 610590) rho GTPase-activating prot (1491 aa)
initn: 7623 init1: 7623 opt: 7623 Z-score: 3947.8 bits: 742.7 E(85289): 3.7e-213
Smith-Waterman score: 7623; 100.0% identity (100.0% similar) in 1118 aa overlap (3-1120:21-1138)
10 20 30 40
pF1KA1 MEQLPLGPRDGCSPRRPFPWQGPRTLLLYKSPQDGFGFTLRH
::::::::::::::::::::::::::::::::::::::::
NP_001 MNGVAFCLVGIPPRPEPRPPQLPLGPRDGCSPRRPFPWQGPRTLLLYKSPQDGFGFTLRH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA1 FIVYPPESAVHCSLKEEENGGRGGGPSPRYRLEPMDTIFVKNVKEDGPAHRAGLRTGDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIVYPPESAVHCSLKEEENGGRGGGPSPRYRLEPMDTIFVKNVKEDGPAHRAGLRTGDRL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 VKVNGESVIGKTYSQVIALIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNEPYSGEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKVNGESVIGKTYSQVIALIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNEPYSGEAR
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 SIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPRSPAAWSDPGLRVPPAARAHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPRSPAAWSDPGLRVPPAARAHL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA1 DNSSLGMSQPRPSPGAFPHLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQVPRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNSSLGMSQPRPSPGAFPHLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQVPRRA
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA1 GERRCPAMAPRARSASQDRLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLSRATR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GERRCPAMAPRARSASQDRLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLSRATR
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 SAEALGPGALVSPRFERCGWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGYIGYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAEALGPGALVSPRFERCGWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGYIGYR
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 SYSPSFQRRTGLLHALSFRDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTRALEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYSPSFQRRTGLLHALSFRDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTRALEP
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 PAEDRGDEVVLRQKPPTGRKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPLATTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAEDRGDEVVLRQKPPTGRKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPLATTE
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA1 DSLASIPFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRHYSQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSLASIPFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRHYSQD
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA1 CSSIKAGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSSIKAGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSL
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA1 DSWGTSEDADAPSKRHSTSDLSDATFSDIRREGWLYYKQILTKKGKKAGSGLRQWKRVYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSWGTSEDADAPSKRHSTSDLSDATFSDIRREGWLYYKQILTKKGKKAGSGLRQWKRVYA
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA1 ALRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTT
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA1 ADFCEYLFQAEDRDDMLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSSGPKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADFCEYLFQAEDRDDMLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSSGPKA
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA1 DSSPKGSRGLGGLKSEFLKQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSPKGSRGLGGLKSEFLKQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAP
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA1 RAFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRG
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA1 PGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKL
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KA1 IRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMP
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KA1 DRYKIVETLIQHSDWFFSDEEDKGERTPVGDKEPQAVPNIEYLLPNIGRTVPPGDPGSAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRYKIVETLIQHSDWFFSDEEDKGERTPVGDKEPQAVPNIEYLLPNIGRTVPPGDPGSDS
1090 1100 1110 1120 1130 1140
pF1KA1 LLEI
NP_001 TTCSSAKSKGSWAPKKEPYAREMLAISFISAVNRKRKKRREARGLGSSTDDDSEQEAHKP
1150 1160 1170 1180 1190 1200
>>XP_011523375 (OMIM: 610590) PREDICTED: rho GTPase-acti (1476 aa)
initn: 7616 init1: 7616 opt: 7616 Z-score: 3944.3 bits: 742.1 E(85289): 5.9e-213
Smith-Waterman score: 7616; 100.0% identity (100.0% similar) in 1117 aa overlap (4-1120:7-1123)
10 20 30 40 50
pF1KA1 MEQLPLGPRDGCSPRRPFPWQGPRTLLLYKSPQDGFGFTLRHFIVYPPESAVHCSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPLERGLPLGPRDGCSPRRPFPWQGPRTLLLYKSPQDGFGFTLRHFIVYPPESAVHCSLK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA1 EEENGGRGGGPSPRYRLEPMDTIFVKNVKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEENGGRGGGPSPRYRLEPMDTIFVKNVKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA1 VIALIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIALIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNEPYSGEARSIPEPPPICYPRKTY
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA1 APPARASTRATMVPEPTSALPSDPRSPAAWSDPGLRVPPAARAHLDNSSLGMSQPRPSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APPARASTRATMVPEPTSALPSDPRSPAAWSDPGLRVPPAARAHLDNSSLGMSQPRPSPG
190 200 210 220 230 240
240 250 260 270 280 290
pF1KA1 AFPHLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQVPRRAGERRCPAMAPRARSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFPHLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQVPRRAGERRCPAMAPRARSA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 SQDRLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLSRATRSAEALGPGALVSPRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQDRLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLSRATRSAEALGPGALVSPRF
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 ERCGWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGYIGYRSYSPSFQRRTGLLHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERCGWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGYIGYRSYSPSFQRRTGLLHA
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 LSFRDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTRALEPPAEDRGDEVVLRQKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSFRDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTRALEPPAEDRGDEVVLRQKP
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 PTGRKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPLATTEDSLASIPFIDEPTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTGRKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPLATTEDSLASIPFIDEPTSP
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 SIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRHYSQDCSSIKAGRRSSYLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRHYSQDCSSIKAGRRSSYLLA
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 ITTERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSLDSWGTSEDADAPSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITTERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSLDSWGTSEDADAPSKR
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 HSTSDLSDATFSDIRREGWLYYKQILTKKGKKAGSGLRQWKRVYAALRARSLSLSKERRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSTSDLSDATFSDIRREGWLYYKQILTKKGKKAGSGLRQWKRVYAALRARSLSLSKERRE
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 PGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDD
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 MLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKS
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA1 EFLKQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFLKQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEECQPATE
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA1 NQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDINLQDERWQDLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDINLQDERWQDLN
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA1 VISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHYYETLKFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHYYETLKFL
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA1 VGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDW
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120
pF1KA1 FFSDEEDKGERTPVGDKEPQAVPNIEYLLPNIGRTVPPGDPGSADLLEI
:::::::::::::::::::::::::::::::::::::::::::
XP_011 FFSDEEDKGERTPVGDKEPQAVPNIEYLLPNIGRTVPPGDPGSDSTTCSSAKSKGSWAPK
1090 1100 1110 1120 1130 1140
XP_011 KEPYAREMLAISFISAVNRKRKKRREARGLGSSTDDDSEQEAHKPGAGATAPGTQERPQG
1150 1160 1170 1180 1190 1200
>>XP_016880391 (OMIM: 610590) PREDICTED: rho GTPase-acti (1119 aa)
initn: 7396 init1: 7396 opt: 7404 Z-score: 3836.5 bits: 721.7 E(85289): 5.9e-207
Smith-Waterman score: 7404; 99.2% identity (99.4% similar) in 1099 aa overlap (3-1099:21-1119)
10 20 30 40
pF1KA1 MEQLPLGPRDGCSPRRPFPWQGPRTLLLYKSPQDGFGFTLRH
::::::::::::::::::::::::::::::::::::::::
XP_016 MNGVAFCLVGIPPRPEPRPPQLPLGPRDGCSPRRPFPWQGPRTLLLYKSPQDGFGFTLRH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA1 FIVYPPESAVHCSLKEEENGGRGGGPSPRYRLEPMDTIFVKNVKEDGPAHRAGLRTGDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIVYPPESAVHCSLKEEENGGRGGGPSPRYRLEPMDTIFVKNVKEDGPAHRAGLRTGDRL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 VKVNGESVIGKTYSQVIALIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNEPYSGEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKVNGESVIGKTYSQVIALIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNEPYSGEAR
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 SIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPRSPAAWSDPGLRVPPAARAHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPRSPAAWSDPGLRVPPAARAHL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA1 DNSSLGMSQPRPSPGAFPHLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQVPRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNSSLGMSQPRPSPGAFPHLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQVPRRA
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA1 GERRCPAMAPRARSASQDRLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLSRATR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GERRCPAMAPRARSASQDRLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLSRATR
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 SAEALGPGALVSPRFERCGWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGYIGYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAEALGPGALVSPRFERCGWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGYIGYR
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 SYSPSFQRRTGLLHALSFRDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTRALEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYSPSFQRRTGLLHALSFRDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTRALEP
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 PAEDRGDEVVLRQKPPTGRKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPLATTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAEDRGDEVVLRQKPPTGRKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPLATTE
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA1 DSLASIPFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRHYSQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSLASIPFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRHYSQD
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA1 CSSIKAGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSSIKAGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSL
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA1 DSWGTSEDADAPSKRHSTSDLSDATFSDIRREGWLYYKQILTKKGKKAGSGLRQWKRVYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSWGTSEDADAPSKRHSTSDLSDATFSDIRREGWLYYKQILTKKGKKAGSGLRQWKRVYA
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA1 ALRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTT
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA1 ADFCEYLFQAEDRDDMLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSSGPKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADFCEYLFQAEDRDDMLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSSGPKA
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA1 DSSPKGSRGLGGLKSEFLKQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSSPKGSRGLGGLKSEFLKQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAP
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA1 RAFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRG
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA1 PGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKL
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KA1 IRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMP
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KA1 DRYKIVETLIQHSDWFFSDEEDKGERT--PVGDKEPQAVPNIEYLLPNIGRTVPPGDPGS
:::::::::::::::::::::::::: :: . :. :
XP_016 DRYKIVETLIQHSDWFFSDEEDKGERILPPVVQPSPRYV
1090 1100 1110
pF1KA1 ADLLEI
>>XP_006722056 (OMIM: 610590) PREDICTED: rho GTPase-acti (1249 aa)
initn: 7396 init1: 7396 opt: 7405 Z-score: 3836.4 bits: 721.9 E(85289): 6e-207
Smith-Waterman score: 7405; 97.5% identity (98.2% similar) in 1122 aa overlap (3-1121:21-1142)
10 20 30 40
pF1KA1 MEQLPLGPRDGCSPRRPFPWQGPRTLLLYKSPQDGFGFTLRH
::::::::::::::::::::::::::::::::::::::::
XP_006 MNGVAFCLVGIPPRPEPRPPQLPLGPRDGCSPRRPFPWQGPRTLLLYKSPQDGFGFTLRH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA1 FIVYPPESAVHCSLKEEENGGRGGGPSPRYRLEPMDTIFVKNVKEDGPAHRAGLRTGDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FIVYPPESAVHCSLKEEENGGRGGGPSPRYRLEPMDTIFVKNVKEDGPAHRAGLRTGDRL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 VKVNGESVIGKTYSQVIALIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNEPYSGEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKVNGESVIGKTYSQVIALIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNEPYSGEAR
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 SIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPRSPAAWSDPGLRVPPAARAHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPRSPAAWSDPGLRVPPAARAHL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA1 DNSSLGMSQPRPSPGAFPHLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQVPRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DNSSLGMSQPRPSPGAFPHLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQVPRRA
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA1 GERRCPAMAPRARSASQDRLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLSRATR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GERRCPAMAPRARSASQDRLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLSRATR
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 SAEALGPGALVSPRFERCGWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGYIGYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SAEALGPGALVSPRFERCGWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGYIGYR
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 SYSPSFQRRTGLLHALSFRDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTRALEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SYSPSFQRRTGLLHALSFRDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTRALEP
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 PAEDRGDEVVLRQKPPTGRKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPLATTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PAEDRGDEVVLRQKPPTGRKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPLATTE
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA1 DSLASIPFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRHYSQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSLASIPFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRHYSQD
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA1 CSSIKAGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CSSIKAGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSL
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA1 DSWGTSEDADAPSKRHSTSDLSDATFSDIRREGWLYYKQILTKKGKKAGSGLRQWKRVYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSWGTSEDADAPSKRHSTSDLSDATFSDIRREGWLYYKQILTKKGKKAGSGLRQWKRVYA
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA1 ALRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTT
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA1 ADFCEYLFQAEDRDDMLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSSGPKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ADFCEYLFQAEDRDDMLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSSGPKA
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA1 DSSPKGSRGLGGLKSEFLKQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSSPKGSRGLGGLKSEFLKQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAP
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA1 RAFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RAFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRG
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA1 PGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKL
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KA1 IRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMP
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110
pF1KA1 DRYKIVETLIQHSDWFFSDEEDKGERT--PVGDKEPQAV-PNIEYLLPNIGRTVPPGDPG
:::::::::::::::::::::::::: :: . :.. : . :. : . :.
XP_006 DRYKIVETLIQHSDWFFSDEEDKGERILPPVVQPSPRVRGPPRRSRTPGRCWRSPSSRPS
1090 1100 1110 1120 1130 1140
1120
pF1KA1 SADLLEI
.:
XP_006 TASARSGGRRGGWAAAPTTTRSRRRTSLGRGPQRRGLRSGRRGRCLAPSPPRPPDASVPR
1150 1160 1170 1180 1190 1200
>>XP_011523379 (OMIM: 610590) PREDICTED: rho GTPase-acti (1117 aa)
initn: 7396 init1: 7396 opt: 7400 Z-score: 3834.5 bits: 721.3 E(85289): 7.6e-207
Smith-Waterman score: 7400; 99.4% identity (99.5% similar) in 1096 aa overlap (3-1096:21-1116)
10 20 30 40
pF1KA1 MEQLPLGPRDGCSPRRPFPWQGPRTLLLYKSPQDGFGFTLRH
::::::::::::::::::::::::::::::::::::::::
XP_011 MNGVAFCLVGIPPRPEPRPPQLPLGPRDGCSPRRPFPWQGPRTLLLYKSPQDGFGFTLRH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA1 FIVYPPESAVHCSLKEEENGGRGGGPSPRYRLEPMDTIFVKNVKEDGPAHRAGLRTGDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FIVYPPESAVHCSLKEEENGGRGGGPSPRYRLEPMDTIFVKNVKEDGPAHRAGLRTGDRL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 VKVNGESVIGKTYSQVIALIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNEPYSGEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKVNGESVIGKTYSQVIALIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNEPYSGEAR
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 SIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPRSPAAWSDPGLRVPPAARAHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPRSPAAWSDPGLRVPPAARAHL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA1 DNSSLGMSQPRPSPGAFPHLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQVPRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNSSLGMSQPRPSPGAFPHLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQVPRRA
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA1 GERRCPAMAPRARSASQDRLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLSRATR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GERRCPAMAPRARSASQDRLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLSRATR
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 SAEALGPGALVSPRFERCGWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGYIGYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAEALGPGALVSPRFERCGWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGYIGYR
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 SYSPSFQRRTGLLHALSFRDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTRALEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYSPSFQRRTGLLHALSFRDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTRALEP
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 PAEDRGDEVVLRQKPPTGRKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPLATTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAEDRGDEVVLRQKPPTGRKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPLATTE
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA1 DSLASIPFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRHYSQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSLASIPFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRHYSQD
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA1 CSSIKAGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSSIKAGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSL
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA1 DSWGTSEDADAPSKRHSTSDLSDATFSDIRREGWLYYKQILTKKGKKAGSGLRQWKRVYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSWGTSEDADAPSKRHSTSDLSDATFSDIRREGWLYYKQILTKKGKKAGSGLRQWKRVYA
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA1 ALRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTT
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA1 ADFCEYLFQAEDRDDMLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSSGPKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADFCEYLFQAEDRDDMLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSSGPKA
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA1 DSSPKGSRGLGGLKSEFLKQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSSPKGSRGLGGLKSEFLKQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAP
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA1 RAFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRG
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA1 PGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKL
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KA1 IRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMP
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KA1 DRYKIVETLIQHSDWFFSDEEDKGERT--PVGDKEPQAVPNIEYLLPNIGRTVPPGDPGS
:::::::::::::::::::::::::: :: . :
XP_011 DRYKIVETLIQHSDWFFSDEEDKGERILPPVVQPSPS
1090 1100 1110
pF1KA1 ADLLEI
>>XP_011523376 (OMIM: 610590) PREDICTED: rho GTPase-acti (1397 aa)
initn: 7069 init1: 7069 opt: 7069 Z-score: 3662.5 bits: 689.9 E(85289): 2.9e-197
Smith-Waterman score: 7069; 100.0% identity (100.0% similar) in 1044 aa overlap (77-1120:1-1044)
50 60 70 80 90 100
pF1KA1 PPESAVHCSLKEEENGGRGGGPSPRYRLEPMDTIFVKNVKEDGPAHRAGLRTGDRLVKVN
::::::::::::::::::::::::::::::
XP_011 MDTIFVKNVKEDGPAHRAGLRTGDRLVKVN
10 20 30
110 120 130 140 150 160
pF1KA1 GESVIGKTYSQVIALIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNEPYSGEARSIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GESVIGKTYSQVIALIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNEPYSGEARSIPE
40 50 60 70 80 90
170 180 190 200 210 220
pF1KA1 PPPICYPRKTYAPPARASTRATMVPEPTSALPSDPRSPAAWSDPGLRVPPAARAHLDNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPICYPRKTYAPPARASTRATMVPEPTSALPSDPRSPAAWSDPGLRVPPAARAHLDNSS
100 110 120 130 140 150
230 240 250 260 270 280
pF1KA1 LGMSQPRPSPGAFPHLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQVPRRAGERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGMSQPRPSPGAFPHLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQVPRRAGERR
160 170 180 190 200 210
290 300 310 320 330 340
pF1KA1 CPAMAPRARSASQDRLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLSRATRSAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPAMAPRARSASQDRLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLSRATRSAEA
220 230 240 250 260 270
350 360 370 380 390 400
pF1KA1 LGPGALVSPRFERCGWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGYIGYRSYSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGPGALVSPRFERCGWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGYIGYRSYSP
280 290 300 310 320 330
410 420 430 440 450 460
pF1KA1 SFQRRTGLLHALSFRDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTRALEPPAED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFQRRTGLLHALSFRDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTRALEPPAED
340 350 360 370 380 390
470 480 490 500 510 520
pF1KA1 RGDEVVLRQKPPTGRKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPLATTEDSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGDEVVLRQKPPTGRKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPLATTEDSLA
400 410 420 430 440 450
530 540 550 560 570 580
pF1KA1 SIPFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRHYSQDCSSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIPFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRHYSQDCSSI
460 470 480 490 500 510
590 600 610 620 630 640
pF1KA1 KAGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSLDSWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSLDSWG
520 530 540 550 560 570
650 660 670 680 690 700
pF1KA1 TSEDADAPSKRHSTSDLSDATFSDIRREGWLYYKQILTKKGKKAGSGLRQWKRVYAALRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSEDADAPSKRHSTSDLSDATFSDIRREGWLYYKQILTKKGKKAGSGLRQWKRVYAALRA
580 590 600 610 620 630
710 720 730 740 750 760
pF1KA1 RSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTTADFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTTADFC
640 650 660 670 680 690
770 780 790 800 810 820
pF1KA1 EYLFQAEDRDDMLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSSGPKADSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYLFQAEDRDDMLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSSGPKADSSP
700 710 720 730 740 750
830 840 850 860 870 880
pF1KA1 KGSRGLGGLKSEFLKQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAPRAFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGSRGLGGLKSEFLKQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAPRAFG
760 770 780 790 800 810
890 900 910 920 930 940
pF1KA1 VRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDI
820 830 840 850 860 870
950 960 970 980 990 1000
pF1KA1 NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDL
880 890 900 910 920 930
1010 1020 1030 1040 1050 1060
pF1KA1 PGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYK
940 950 960 970 980 990
1070 1080 1090 1100 1110 1120
pF1KA1 IVETLIQHSDWFFSDEEDKGERTPVGDKEPQAVPNIEYLLPNIGRTVPPGDPGSADLLEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVETLIQHSDWFFSDEEDKGERTPVGDKEPQAVPNIEYLLPNIGRTVPPGDPGSDSTTCS
1000 1010 1020 1030 1040 1050
XP_011 SAKSKGSWAPKKEPYAREMLAISFISAVNRKRKKRREARGLGSSTDDDSEQEAHKPGAGA
1060 1070 1080 1090 1100 1110
>>XP_011523377 (OMIM: 610590) PREDICTED: rho GTPase-acti (1285 aa)
initn: 6332 init1: 6332 opt: 6332 Z-score: 3283.0 bits: 619.5 E(85289): 4e-176
Smith-Waterman score: 6332; 100.0% identity (100.0% similar) in 932 aa overlap (189-1120:1-932)
160 170 180 190 200 210
pF1KA1 GEARSIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPRSPAAWSDPGLRVPPAA
::::::::::::::::::::::::::::::
XP_011 MVPEPTSALPSDPRSPAAWSDPGLRVPPAA
10 20 30
220 230 240 250 260 270
pF1KA1 RAHLDNSSLGMSQPRPSPGAFPHLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAHLDNSSLGMSQPRPSPGAFPHLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQV
40 50 60 70 80 90
280 290 300 310 320 330
pF1KA1 PRRAGERRCPAMAPRARSASQDRLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRRAGERRCPAMAPRARSASQDRLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLS
100 110 120 130 140 150
340 350 360 370 380 390
pF1KA1 RATRSAEALGPGALVSPRFERCGWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RATRSAEALGPGALVSPRFERCGWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGY
160 170 180 190 200 210
400 410 420 430 440 450
pF1KA1 IGYRSYSPSFQRRTGLLHALSFRDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGYRSYSPSFQRRTGLLHALSFRDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTR
220 230 240 250 260 270
460 470 480 490 500 510
pF1KA1 ALEPPAEDRGDEVVLRQKPPTGRKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALEPPAEDRGDEVVLRQKPPTGRKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPL
280 290 300 310 320 330
520 530 540 550 560 570
pF1KA1 ATTEDSLASIPFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATTEDSLASIPFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRH
340 350 360 370 380 390
580 590 600 610 620 630
pF1KA1 YSQDCSSIKAGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSQDCSSIKAGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFT
400 410 420 430 440 450
640 650 660 670 680 690
pF1KA1 DGSLDSWGTSEDADAPSKRHSTSDLSDATFSDIRREGWLYYKQILTKKGKKAGSGLRQWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGSLDSWGTSEDADAPSKRHSTSDLSDATFSDIRREGWLYYKQILTKKGKKAGSGLRQWK
460 470 480 490 500 510
700 710 720 730 740 750
pF1KA1 RVYAALRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVYAALRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVF
520 530 540 550 560 570
760 770 780 790 800 810
pF1KA1 RLTTADFCEYLFQAEDRDDMLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLTTADFCEYLFQAEDRDDMLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSS
580 590 600 610 620 630
820 830 840 850 860 870
pF1KA1 GPKADSSPKGSRGLGGLKSEFLKQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPKADSSPKGSRGLGGLKSEFLKQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNK
640 650 660 670 680 690
880 890 900 910 920 930
pF1KA1 KAAPRAFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAAPRAFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQ
700 710 720 730 740 750
940 950 960 970 980 990
pF1KA1 LNRGPGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNRGPGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRT
760 770 780 790 800 810
1000 1010 1020 1030 1040 1050
pF1KA1 LRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMV
820 830 840 850 860 870
1060 1070 1080 1090 1100 1110
pF1KA1 THMPDRYKIVETLIQHSDWFFSDEEDKGERTPVGDKEPQAVPNIEYLLPNIGRTVPPGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THMPDRYKIVETLIQHSDWFFSDEEDKGERTPVGDKEPQAVPNIEYLLPNIGRTVPPGDP
880 890 900 910 920 930
1120
pF1KA1 GSADLLEI
::
XP_011 GSDSTTCSSAKSKGSWAPKKEPYAREMLAISFISAVNRKRKKRREARGLGSSTDDDSEQE
940 950 960 970 980 990
>>XP_006722055 (OMIM: 610590) PREDICTED: rho GTPase-acti (1408 aa)
initn: 4727 init1: 4727 opt: 4735 Z-score: 2458.9 bits: 467.2 E(85289): 3.2e-130
Smith-Waterman score: 6898; 92.6% identity (92.6% similar) in 1118 aa overlap (3-1120:21-1055)
10 20 30 40
pF1KA1 MEQLPLGPRDGCSPRRPFPWQGPRTLLLYKSPQDGFGFTLRH
::::::::::::::::::::::::::::::::::::::::
XP_006 MNGVAFCLVGIPPRPEPRPPQLPLGPRDGCSPRRPFPWQGPRTLLLYKSPQDGFGFTLRH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA1 FIVYPPESAVHCSLKEEENGGRGGGPSPRYRLEPMDTIFVKNVKEDGPAHRAGLRTGDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FIVYPPESAVHCSLKEEENGGRGGGPSPRYRLEPMDTIFVKNVKEDGPAHRAGLRTGDRL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 VKVNGESVIGKTYSQVIALIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNEPYSGEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKVNGESVIGKTYSQVIALIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNEPYSGEAR
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 SIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPRSPAAWSDPGLRVPPAARAHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPRSPAAWSDPGLRVPPAARAHL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA1 DNSSLGMSQPRPSPGAFPHLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQVPRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DNSSLGMSQPRPSPGAFPHLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQVPRRA
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA1 GERRCPAMAPRARSASQDRLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLSRATR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GERRCPAMAPRARSASQDRLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLSRATR
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 SAEALGPGALVSPRFERCGWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGYIGYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SAEALGPGALVSPRFERCGWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGYIGYR
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 SYSPSFQRRTGLLHALSFRDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTRALEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SYSPSFQRRTGLLHALSFRDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTRALEP
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 PAEDRGDEVVLRQKPPTGRKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPLATTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PAEDRGDEVVLRQKPPTGRKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPLATTE
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA1 DSLASIPFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRHYSQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSLASIPFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRHYSQD
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA1 CSSIKAGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CSSIKAGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSL
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA1 DSWGTSEDADAPSKRHSTSDLSDATFSDIRREGWLYYKQILTKKGKKAGSGLRQWKRVYA
::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSWGTSEDADAPSKRHSTSDLSDATFSDIRREGWLYYKQILTKKGK--------------
670 680 690 700
710 720 730 740 750 760
pF1KA1 ALRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTT
XP_006 ------------------------------------------------------------
770 780 790 800 810 820
pF1KA1 ADFCEYLFQAEDRDDMLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSSGPKA
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ---------AEDRDDMLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSSGPKA
710 720 730 740 750
830 840 850 860 870 880
pF1KA1 DSSPKGSRGLGGLKSEFLKQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSSPKGSRGLGGLKSEFLKQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAP
760 770 780 790 800 810
890 900 910 920 930 940
pF1KA1 RAFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RAFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRG
820 830 840 850 860 870
950 960 970 980 990 1000
pF1KA1 PGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKL
880 890 900 910 920 930
1010 1020 1030 1040 1050 1060
pF1KA1 IRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMP
940 950 960 970 980 990
1070 1080 1090 1100 1110 1120
pF1KA1 DRYKIVETLIQHSDWFFSDEEDKGERTPVGDKEPQAVPNIEYLLPNIGRTVPPGDPGSAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DRYKIVETLIQHSDWFFSDEEDKGERTPVGDKEPQAVPNIEYLLPNIGRTVPPGDPGSDS
1000 1010 1020 1030 1040 1050
pF1KA1 LLEI
XP_006 TTCSSAKSKGSWAPKKEPYAREMLAISFISAVNRKRKKRREARGLGSSTDDDSEQEAHKP
1060 1070 1080 1090 1100 1110
1126 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 02:21:53 2016 done: Sat Nov 5 02:21:55 2016
Total Scan time: 13.710 Total Display time: 0.480
Function used was FASTA [36.3.4 Apr, 2011]