Result of FASTA (omim) for
pFN21AB5467
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5467, 328 aa
1>>>pF1KB5467 328 - 328 aa - 328 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3497+/-0.000296; mu= 16.1569+/- 0.019
mean_var=75.9413+/-15.714, 0's: 0 Z-trim(118.0): 71 B-trim: 161 in 1/51
Lambda= 0.147175
statistics sampled from 30529 (30601) to 30529 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.724), E-opt: 0.2 (0.359), width: 16
Scan time: 8.710
The best scores are: opt bits E(85289)
NP_001208 (OMIM: 604644) carbonic anhydrase-relate ( 328) 2244 485.5 6.6e-137
NP_001076002 (OMIM: 604642) carbonic anhydrase-rel ( 328) 1223 268.7 1.2e-71
NP_064563 (OMIM: 604642) carbonic anhydrase-relate ( 328) 1223 268.7 1.2e-71
NP_001076003 (OMIM: 604642) carbonic anhydrase-rel ( 328) 1223 268.7 1.2e-71
XP_016880367 (OMIM: 604642) PREDICTED: carbonic an ( 231) 874 194.5 1.8e-49
NP_000058 (OMIM: 259730,611492) carbonic anhydrase ( 260) 487 112.3 1.1e-24
NP_001730 (OMIM: 114761,615751) carbonic anhydrase ( 305) 449 104.3 3.3e-22
NP_940986 (OMIM: 611436) carbonic anhydrase 13 [Ho ( 262) 447 103.9 4e-22
XP_016884736 (OMIM: 300230) PREDICTED: carbonic an ( 278) 438 102.0 1.6e-21
NP_009151 (OMIM: 300230) carbonic anhydrase 5B, mi ( 317) 438 102.0 1.7e-21
XP_005274499 (OMIM: 300230) PREDICTED: carbonic an ( 317) 438 102.0 1.7e-21
NP_005173 (OMIM: 114770) carbonic anhydrase 7 isof ( 264) 433 100.9 3.1e-21
NP_004047 (OMIM: 114815,613227) carbonic anhydrase ( 290) 430 100.3 5.3e-21
NP_001308766 (OMIM: 114815,613227) carbonic anhydr ( 290) 430 100.3 5.3e-21
NP_005172 (OMIM: 114750) carbonic anhydrase 3 [Hom ( 260) 429 100.0 5.6e-21
NP_001122301 (OMIM: 114800) carbonic anhydrase 1 i ( 261) 412 96.4 6.9e-20
NP_001122303 (OMIM: 114800) carbonic anhydrase 1 i ( 261) 412 96.4 6.9e-20
NP_001158302 (OMIM: 114800) carbonic anhydrase 1 i ( 261) 412 96.4 6.9e-20
NP_001122302 (OMIM: 114800) carbonic anhydrase 1 i ( 261) 412 96.4 6.9e-20
NP_001729 (OMIM: 114800) carbonic anhydrase 1 isof ( 261) 412 96.4 6.9e-20
XP_016879135 (OMIM: 114761,615751) PREDICTED: carb ( 314) 397 93.3 7.2e-19
XP_006711322 (OMIM: 604832) PREDICTED: carbonic an ( 318) 394 92.7 1.1e-18
XP_005245117 (OMIM: 604832) PREDICTED: carbonic an ( 319) 394 92.7 1.1e-18
XP_005245116 (OMIM: 604832) PREDICTED: carbonic an ( 336) 394 92.7 1.2e-18
NP_036245 (OMIM: 604832) carbonic anhydrase 14 pre ( 337) 394 92.7 1.2e-18
XP_011521613 (OMIM: 114770) PREDICTED: carbonic an ( 242) 386 90.9 3e-18
NP_001308767 (OMIM: 114815,613227) carbonic anhydr ( 263) 385 90.7 3.7e-18
XP_016884737 (OMIM: 300230) PREDICTED: carbonic an ( 248) 367 86.9 5e-17
XP_011521614 (OMIM: 114770) PREDICTED: carbonic an ( 208) 363 86.0 7.8e-17
NP_001014435 (OMIM: 114770) carbonic anhydrase 7 i ( 208) 363 86.0 7.8e-17
XP_005256193 (OMIM: 114770) PREDICTED: carbonic an ( 208) 363 86.0 7.8e-17
XP_016869307 (OMIM: 114815,613227) PREDICTED: carb ( 206) 359 85.1 1.4e-16
NP_001207 (OMIM: 603179) carbonic anhydrase 9 prec ( 459) 352 83.9 7.3e-16
NP_001278896 (OMIM: 114800) carbonic anhydrase 1 i ( 195) 347 82.5 7.8e-16
NP_996808 (OMIM: 143860,603263) carbonic anhydrase ( 343) 347 82.7 1.2e-15
NP_001209 (OMIM: 143860,603263) carbonic anhydrase ( 354) 347 82.7 1.2e-15
NP_001257429 (OMIM: 114780) carbonic anhydrase 6 i ( 313) 342 81.6 2.4e-15
XP_011540385 (OMIM: 114780) PREDICTED: carbonic an ( 294) 331 79.3 1.1e-14
NP_001206 (OMIM: 114780) carbonic anhydrase 6 isof ( 308) 331 79.3 1.2e-14
XP_011540386 (OMIM: 114780) PREDICTED: carbonic an ( 324) 331 79.3 1.2e-14
XP_016856382 (OMIM: 604832) PREDICTED: carbonic an ( 263) 327 78.4 1.9e-14
XP_006711324 (OMIM: 604832) PREDICTED: carbonic an ( 281) 327 78.4 2e-14
XP_011507681 (OMIM: 604832) PREDICTED: carbonic an ( 323) 327 78.4 2.2e-14
XP_005265410 (OMIM: 176886) PREDICTED: receptor-ty (1416) 319 77.2 2.3e-13
NP_002832 (OMIM: 176886) receptor-type tyrosine-pr (1445) 319 77.2 2.3e-13
NP_001280571 (OMIM: 143860,603263) carbonic anhydr ( 283) 297 72.0 1.6e-12
NP_001280604 (OMIM: 259730,611492) carbonic anhydr ( 159) 293 71.0 1.9e-12
XP_011521612 (OMIM: 114761,615751) PREDICTED: carb ( 222) 287 69.8 5.9e-12
XP_011521611 (OMIM: 114761,615751) PREDICTED: carb ( 376) 289 70.4 6.7e-12
NP_000708 (OMIM: 114760,600852) carbonic anhydrase ( 312) 279 68.2 2.5e-11
>>NP_001208 (OMIM: 604644) carbonic anhydrase-related pr (328 aa)
initn: 2244 init1: 2244 opt: 2244 Z-score: 2578.9 bits: 485.5 E(85289): 6.6e-137
Smith-Waterman score: 2244; 100.0% identity (100.0% similar) in 328 aa overlap (1-328:1-328)
10 20 30 40 50 60
pF1KB5 MGAAARLSAPRALVLWAALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGAAARLSAPRALVLWAALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LCAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPAPRPVVNVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPAPRPVVNVS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GGPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPNG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LAILSLFVNVASTSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAILSLFVNVASTSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LSTPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNSRPLQPLAHRALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSTPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNSRPLQPLAHRALR
250 260 270 280 290 300
310 320
pF1KB5 GNRDPRHPERRCRGPNYRLHVDGVPHGR
::::::::::::::::::::::::::::
NP_001 GNRDPRHPERRCRGPNYRLHVDGVPHGR
310 320
>>NP_001076002 (OMIM: 604642) carbonic anhydrase-related (328 aa)
initn: 1210 init1: 1210 opt: 1223 Z-score: 1407.3 bits: 268.7 E(85289): 1.2e-71
Smith-Waterman score: 1223; 58.9% identity (84.0% similar) in 287 aa overlap (32-318:30-314)
10 20 30 40 50 60
pF1KB5 GAAARLSAPRALVLWAALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWSL
: ::.::. .::.::: : ::::::.::.:
NP_001 MEIVWEVLFLLQANFIVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNL
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 CAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPAPRPVVNVSG
:.::::::::..: .....:::: :::..:::.:. ::.::::::::. . .::.::
NP_001 CSVGKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 GPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPNGL
::. ::::: :.:: ::..:. :::: .: :.::.::::::.:.::: : . :...::::
NP_001 GPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 AILSLFVNVASTSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSL
...:.:..:...:::::.:.:::::::::.::::::.:: :..: :.::. .::::.::.
NP_001 VVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSM
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB5 STPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNSRPLQPLAHRALRG
. ::: ::..::.... . :: .::::::::::: ::::: :.: : ::.::: .: .:
NP_001 TIPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRT
240 250 260 270 280 290
310 320
pF1KB5 NRDPRHPERRCRGPNYRLHVDGVPHGR
: . . : :: :
NP_001 NINFSLQGKDC--PNNRAQKLQYRVNEWLLK
300 310 320
>>NP_064563 (OMIM: 604642) carbonic anhydrase-related pr (328 aa)
initn: 1210 init1: 1210 opt: 1223 Z-score: 1407.3 bits: 268.7 E(85289): 1.2e-71
Smith-Waterman score: 1223; 58.9% identity (84.0% similar) in 287 aa overlap (32-318:30-314)
10 20 30 40 50 60
pF1KB5 GAAARLSAPRALVLWAALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWSL
: ::.::. .::.::: : ::::::.::.:
NP_064 MEIVWEVLFLLQANFIVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNL
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 CAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPAPRPVVNVSG
:.::::::::..: .....:::: :::..:::.:. ::.::::::::. . .::.::
NP_064 CSVGKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 GPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPNGL
::. ::::: :.:: ::..:. :::: .: :.::.::::::.:.::: : . :...::::
NP_064 GPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 AILSLFVNVASTSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSL
...:.:..:...:::::.:.:::::::::.::::::.:: :..: :.::. .::::.::.
NP_064 VVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSM
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB5 STPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNSRPLQPLAHRALRG
. ::: ::..::.... . :: .::::::::::: ::::: :.: : ::.::: .: .:
NP_064 TIPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRT
240 250 260 270 280 290
310 320
pF1KB5 NRDPRHPERRCRGPNYRLHVDGVPHGR
: . . : :: :
NP_064 NINFSLQGKDC--PNNRAQKLQYRVNEWLLK
300 310 320
>>NP_001076003 (OMIM: 604642) carbonic anhydrase-related (328 aa)
initn: 1210 init1: 1210 opt: 1223 Z-score: 1407.3 bits: 268.7 E(85289): 1.2e-71
Smith-Waterman score: 1223; 58.9% identity (84.0% similar) in 287 aa overlap (32-318:30-314)
10 20 30 40 50 60
pF1KB5 GAAARLSAPRALVLWAALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWSL
: ::.::. .::.::: : ::::::.::.:
NP_001 MEIVWEVLFLLQANFIVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNL
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 CAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPAPRPVVNVSG
:.::::::::..: .....:::: :::..:::.:. ::.::::::::. . .::.::
NP_001 CSVGKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 GPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPNGL
::. ::::: :.:: ::..:. :::: .: :.::.::::::.:.::: : . :...::::
NP_001 GPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 AILSLFVNVASTSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSL
...:.:..:...:::::.:.:::::::::.::::::.:: :..: :.::. .::::.::.
NP_001 VVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSM
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB5 STPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNSRPLQPLAHRALRG
. ::: ::..::.... . :: .::::::::::: ::::: :.: : ::.::: .: .:
NP_001 TIPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRT
240 250 260 270 280 290
310 320
pF1KB5 NRDPRHPERRCRGPNYRLHVDGVPHGR
: . . : :: :
NP_001 NINFSLQGKDC--PNNRAQKLQYRVNEWLLK
300 310 320
>>XP_016880367 (OMIM: 604642) PREDICTED: carbonic anhydr (231 aa)
initn: 863 init1: 863 opt: 874 Z-score: 1009.0 bits: 194.5 E(85289): 1.8e-49
Smith-Waterman score: 874; 57.5% identity (82.2% similar) in 219 aa overlap (100-318:1-217)
70 80 90 100 110 120
pF1KB5 PVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPAPRPVVNVSGGPLLYSHR
.::::::::. . .::.::::. ::::
XP_016 MYNTGRHVSLRLDKEHLVNISGGPMTYSHR
10 20 30
130 140 150 160 170 180
pF1KB5 LSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPNGLAILSLFVN
: :.:: ::..:. :::: .: :.::.::::::.:.::: : . :...::::...:.:..
XP_016 LEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIK
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB5 VASTSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSET
:...:::::.:.:::::::::.::::::.:: :..: :.::. .::::.::.. ::: ::
XP_016 VSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYET
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB5 VTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNSRPLQPLAHRALRGNRDPRHPE
..::.... . :: .::::::::::: ::::: :.: : ::.::: .: .: : .
XP_016 ASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQG
160 170 180 190 200 210
310 320
pF1KB5 RRCRGPNYRLHVDGVPHGR
. : :: :
XP_016 KDC--PNNRAQKLQYRVNEWLLK
220 230
>>NP_000058 (OMIM: 259730,611492) carbonic anhydrase 2 i (260 aa)
initn: 442 init1: 199 opt: 487 Z-score: 564.2 bits: 112.3 E(85289): 1.1e-24
Smith-Waterman score: 487; 34.5% identity (68.6% similar) in 258 aa overlap (48-302:12-258)
20 30 40 50 60 70
pF1KB5 ALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWSLCAVGKRQSPVDVELKR
:: : . . . : :.::::::.. .
NP_000 MSHHWGYGKHNGPEHW---HKDFPI-AKGERQSPVDIDTHT
10 20 30
80 90 100 110 120 130
pF1KB5 VLYDPFLPPLRLSTG-GEKLRGTLYNTGR--HVSFLPAPRPVVNVSGGPLLYSHRLSELR
. ::: : :: .: . .:: . :.:. .: : . .: ..:::: ..:: ...
NP_000 AKYDPSLKPLSVSYDQATSLR--ILNNGHAFNVEFDDSQDKAV-LKGGPLDGTYRLIQFH
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB5 LLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPNGLAILSLFVNVASTS
. .:. :: :::: .... ..::..:.:.: . ::.:. : . :.:::.:..:..:.: .
NP_000 FHWGSLDGQGSEHTVDKKKYAAELHLVHWNTK-YGDFGKAVQQPDGLAVLGIFLKVGS-A
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB5 NPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWIL
.: :.... :.. :. :. . . ... . :.:::. . :: :::.::: : ::::.
NP_000 KPGLQKVV--DVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIV
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB5 IDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNSRPLQPLAHRALRGNRDPRHPERRCRG
. . ....: :. ..: :. : .. . . : :: ::: .: ....
NP_000 LKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
220 230 240 250 260
320
pF1KB5 PNYRLHVDGVPHGR
>>NP_001730 (OMIM: 114761,615751) carbonic anhydrase 5A, (305 aa)
initn: 394 init1: 252 opt: 449 Z-score: 519.6 bits: 104.3 E(85289): 3.3e-22
Smith-Waterman score: 449; 33.2% identity (67.2% similar) in 235 aa overlap (65-297:61-290)
40 50 60 70 80 90
pF1KB5 WSYKDNLQGNFVPGPPFWGLVNAAWSLCAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGE
: ::::.... . .::: : :::.: .
NP_001 GRWCSQRSCAWQTSNNTLHPLWTVPVSVPGGTRQSPINIQWRDSVYDPQLKPLRVSYEAA
40 50 60 70 80 90
100 110 120 130 140 150
pF1KB5 KLRGTLYNTGR--HVSFLPAPRPVVNVSGGPLLYSHRLSELRLLFGARDGAGSEHQINHQ
. ..::: .: : : . . ..::::: .::..... .:: . .:::: .. .
NP_001 SCL-YIWNTGYLFQVEFDDATE-ASGISGGPLENHYRLKQFHFHWGAVNEGGSEHTVDGH
100 110 120 130 140
160 170 180 190 200 210
pF1KB5 GFSAEVQLIHFNQELYGNFSAASRGPNGLAILSLFVNVASTSNPFLSRLLNRDTITRISY
.. ::..:.:.:. : :.. : : ::::....:..... . :.::. : . .:..
NP_001 AYPAELHLVHWNSVKYQNYKEAVVGENGLAVIGVFLKLGA-HHQTLQRLV--DILPEIKH
150 160 170 180 190 200
220 230 240 250 260 270
pF1KB5 KNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWILIDRALNITSLQMHSLRLL
:. .. .. :.: . . :: :::.::: .:.::::. . .... :. ..: :
NP_001 KDARAAMRPFDPSTLLPTCWDYWTYAGSLTTPPLTESVTWIIQKEPVEVAPSQLSAFRTL
210 220 230 240 250 260
280 290 300 310 320
pF1KB5 SQNPPSQIFQSLSGNSRPLQPLAHRALRGNRDPRHPERRCRGPNYRLHVDGVPHGR
. .. . . .: :::::: .:
NP_001 LFSALGEEEKMMVNNYRPLQPLMNRKVWASFQATNEGTRS
270 280 290 300
>>NP_940986 (OMIM: 611436) carbonic anhydrase 13 [Homo s (262 aa)
initn: 407 init1: 235 opt: 447 Z-score: 518.2 bits: 103.9 E(85289): 4e-22
Smith-Waterman score: 452; 31.9% identity (62.2% similar) in 270 aa overlap (35-302:6-260)
10 20 30 40 50 60
pF1KB5 ARLSAPRALVLWAALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWSLCAV
:.:... :: : . :
NP_940 MSRLSWGYREH------NGPIHW----KEFFPIAD
10 20
70 80 90 100 110 120
pF1KB5 GKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGR--HVSFLPAPRPVVNVSGG
: .:::.... :.: :: : :: .. . . . :.:. .:.: . : . ::
NP_940 GDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAK-IISNSGHSFNVDFDDTENKSV-LRGG
30 40 50 60 70 80
130 140 150 160 170 180
pF1KB5 PLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPNGLA
:: :.:: ...: .:. : :::: .. ...::....:.:.. : .: :.. :.:::
NP_940 PLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDGLA
90 100 110 120 130 140
190 200 210 220 230 240
pF1KB5 ILSLFVNVASTSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLS
.:..:.... : :... ::. :. :. . ...: :.: :. . :: :::.
NP_940 VLGVFLQIGEP-NSQLQKI--TDTLDSIKEKGKQTRFTNFDLLSLLPPSWDYWTYPGSLT
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB5 TPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNSRPLQPLAHRALRGN
.:: :.::::.. . .::.: :. ..: : . .. : .: :: ::: : .:..
NP_940 VPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRAS
210 220 230 240 250 260
310 320
pF1KB5 RDPRHPERRCRGPNYRLHVDGVPHGR
NP_940 FH
>>XP_016884736 (OMIM: 300230) PREDICTED: carbonic anhydr (278 aa)
initn: 403 init1: 247 opt: 438 Z-score: 507.5 bits: 102.0 E(85289): 1.6e-21
Smith-Waterman score: 438; 32.2% identity (63.1% similar) in 255 aa overlap (50-302:11-256)
20 30 40 50 60 70
pF1KB5 GAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWSLCAVGKRQSPVDVELKRVL
:.: :. : : ::::.... . .
XP_016 MLYQGQVGVHPLWESVD----LVPGGDRQSPINIRWRDSV
10 20 30
80 90 100 110 120 130
pF1KB5 YDPFLPPLRLSTGGEKLRGTLYNTGRH--VSFLPAPRPVVNVSGGPLLYSHRLSELRLLF
::: : :: .: ..:.: : : . : ..:::: ...::..... .
XP_016 YDPGLKPLTISYDPATCLH-VWNNGYSFLVEFEDSTDKSV-IKGGPLEHNYRLKQFHFHW
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB5 GARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPNGLAILSLFVNVASTSNPF
:: :. :::: .. . : ::..:.:.: . :: :. ::::....:..... .
XP_016 GAIDAWGSEHTVDSKCFPAELHLVHWNAVRFENFEDAALEENGLAVIGVFLKLGK-HHKE
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB5 LSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWILIDR
:..:. ::. :..:. . ... :.: . ::.:::.::: ::.::::. .
XP_016 LQKLV--DTLPSIKHKDALVEFGSFDPSCLMPTCPDYWTYSGSLTTPPLSESVTWIIKKQ
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB5 ALNITSLQMHSLRLLSQNPPSQIFQSLSGNSRPLQPLAHRALRGNRDPRHPERRCRGPNY
... :....: : . .. . . : :::::: .:..:..
XP_016 PVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQPLMNRTVRSSFRHDYVLNVQAKPKP
220 230 240 250 260 270
320
pF1KB5 RLHVDGVPHGR
XP_016 ATSQATP
>>NP_009151 (OMIM: 300230) carbonic anhydrase 5B, mitoch (317 aa)
initn: 403 init1: 247 opt: 438 Z-score: 506.7 bits: 102.0 E(85289): 1.7e-21
Smith-Waterman score: 438; 32.2% identity (63.1% similar) in 255 aa overlap (50-302:50-295)
20 30 40 50 60 70
pF1KB5 GAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWSLCAVGKRQSPVDVELKRVL
:.: :. : : ::::.... . .
NP_009 WRKFQIPRFMPARPCSLYTCTYKTRNRALHPLWESVD----LVPGGDRQSPINIRWRDSV
20 30 40 50 60 70
80 90 100 110 120 130
pF1KB5 YDPFLPPLRLSTGGEKLRGTLYNTGRH--VSFLPAPRPVVNVSGGPLLYSHRLSELRLLF
::: : :: .: ..:.: : : . : ..:::: ...::..... .
NP_009 YDPGLKPLTISYDPATCLH-VWNNGYSFLVEFEDSTDKSV-IKGGPLEHNYRLKQFHFHW
80 90 100 110 120 130
140 150 160 170 180 190
pF1KB5 GARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPNGLAILSLFVNVASTSNPF
:: :. :::: .. . : ::..:.:.: . :: :. ::::....:..... .
NP_009 GAIDAWGSEHTVDSKCFPAELHLVHWNAVRFENFEDAALEENGLAVIGVFLKLGK-HHKE
140 150 160 170 180 190
200 210 220 230 240 250
pF1KB5 LSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWILIDR
:..:. ::. :..:. . ... :.: . ::.:::.::: ::.::::. .
NP_009 LQKLV--DTLPSIKHKDALVEFGSFDPSCLMPTCPDYWTYSGSLTTPPLSESVTWIIKKQ
200 210 220 230 240 250
260 270 280 290 300 310
pF1KB5 ALNITSLQMHSLRLLSQNPPSQIFQSLSGNSRPLQPLAHRALRGNRDPRHPERRCRGPNY
... :....: : . .. . . : :::::: .:..:..
NP_009 PVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQPLMNRTVRSSFRHDYVLNVQAKPKP
260 270 280 290 300 310
320
pF1KB5 RLHVDGVPHGR
NP_009 ATSQATP
328 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 12:52:33 2016 done: Sat Nov 5 12:52:34 2016
Total Scan time: 8.710 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]