Result of FASTA (ccds) for
pFN21AE1355
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1355, 282 aa
1>>>pF1KE1355 282 - 282 aa - 282 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9800+/-0.000853; mu= 16.2474+/- 0.052
mean_var=54.2118+/-10.745, 0's: 0 Z-trim(104.3): 16 B-trim: 0 in 0/50
Lambda= 0.174192
statistics sampled from 7837 (7845) to 7837 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.241), width: 16
Scan time: 2.310
The best scores are: opt bits E(32554)
CCDS10507.1 DNASE1 gene_id:1773|Hs108|chr16 ( 282) 1875 479.2 1.4e-135
CCDS2886.1 DNASE1L3 gene_id:1776|Hs108|chr3 ( 305) 795 207.8 7.7e-54
CCDS14747.1 DNASE1L1 gene_id:1774|Hs108|chrX ( 302) 626 165.4 4.6e-41
CCDS42105.1 DNASE1L2 gene_id:1775|Hs108|chr16 ( 299) 556 147.8 9.1e-36
CCDS58836.1 DNASE1L3 gene_id:1776|Hs108|chr3 ( 275) 547 145.5 4.1e-35
>>CCDS10507.1 DNASE1 gene_id:1773|Hs108|chr16 (282 aa)
initn: 1875 init1: 1875 opt: 1875 Z-score: 2547.4 bits: 479.2 E(32554): 1.4e-135
Smith-Waterman score: 1875; 100.0% identity (100.0% similar) in 282 aa overlap (1-282:1-282)
10 20 30 40 50 60
pF1KE1 MRGMKLLGALLALAALLQGAVSLKIAAFNIQTFGETKMSNATLVSYIVQILSRYDIALVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MRGMKLLGALLALAALLQGAVSLKIAAFNIQTFGETKMSNATLVSYIVQILSRYDIALVQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EVRDSHLTAVGKLLDNLNQDAPDTYHYVVSEPLGRNSYKERYLFVYRPDQVSAVDSYYYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EVRDSHLTAVGKLLDNLNQDAPDTYHYVVSEPLGRNSYKERYLFVYRPDQVSAVDSYYYD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 DGCEPCGNDTFNREPAIVRFFSRFTEVREFAIVPLHAAPGDAVAEIDALYDVYLDVQEKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 DGCEPCGNDTFNREPAIVRFFSRFTEVREFAIVPLHAAPGDAVAEIDALYDVYLDVQEKW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GLEDVMLMGDFNAGCSYVRPSQWSSIRLWTSPTFQWLIPDSADTTATPTHCAYDRIVVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 GLEDVMLMGDFNAGCSYVRPSQWSSIRLWTSPTFQWLIPDSADTTATPTHCAYDRIVVAG
190 200 210 220 230 240
250 260 270 280
pF1KE1 MLLRGAVVPDSALPFNFQAAYGLSDQLAQAISDHYPVEVMLK
::::::::::::::::::::::::::::::::::::::::::
CCDS10 MLLRGAVVPDSALPFNFQAAYGLSDQLAQAISDHYPVEVMLK
250 260 270 280
>>CCDS2886.1 DNASE1L3 gene_id:1776|Hs108|chr3 (305 aa)
initn: 678 init1: 364 opt: 795 Z-score: 1080.1 bits: 207.8 E(32554): 7.7e-54
Smith-Waterman score: 795; 44.8% identity (72.4% similar) in 279 aa overlap (7-282:5-282)
10 20 30 40 50 60
pF1KE1 MRGMKLLGALLALAALLQGAVSLKIAAFNIQTFGETKMSNATLVSYIVQILSRYDIALVQ
:. :: : ...:....: .::...:::.:. . . .. ::....: :: ::.
CCDS28 MSRELAPLLLLLLSIHSALAMRICSFNVRSFGESKQEDKNAMDVIVKVIKRCDIILVM
10 20 30 40 50
70 80 90 100 110
pF1KE1 EVRDSHLTAVGKLLDNLNQDAPD--TYHYVVSEPLGRNSYKERYLFVYRPDQVSAVDSYY
:..::. :...::... ::.::.: ::::.:::.: :.:. ::. ::.
CCDS28 EIKDSNNRICPILMEKLNRNSRRGITYNYVISSRLGRNTYKEQYAFLYKEKLVSVKRSYH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 YDDGCEPCGNDTFNREPAIVRFFSRFTEVREFAIVPLHAAPGDAVAEIDALYDVYLDVQE
: : . :.:.::: .: : : : :..:.:.:::..: .: ::: : .:: ::..
CCDS28 YHDY-QDGDADVFSREPFVVWFQSPHTAVKDFVIIPLHTTPETSVKEIDELVEVYTDVKH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 KWGLEDVMLMGDFNAGCSYVRPSQWSSIRLWTSPTFQWLIPDSADTTATP-THCAYDRIV
.: :. ..::::::::::: . :..::: :.: : ::: :. :::. :.:::::::
CCDS28 RWKAENFIFMGDFNAGCSYVPKKAWKNIRLRTDPRFVWLIGDQEDTTVKKSTNCAYDRIV
180 190 200 210 220 230
240 250 260 270 280
pF1KE1 VAGMLLRGAVVPDSALPFNFQAAYGLSDQLAQAISDHYPVEVMLK
. :. . ..::: : :.:: :: :... : .:::.::: :.
CCDS28 LRGQEIVSSVVPKSNSVFDFQKAYKLTEEEALDVSDHFPVEFKLQSSRAFTNSKKSVTLR
240 250 260 270 280 290
CCDS28 KKTKSKRS
300
>>CCDS14747.1 DNASE1L1 gene_id:1774|Hs108|chrX (302 aa)
initn: 562 init1: 275 opt: 626 Z-score: 850.6 bits: 165.4 E(32554): 4.6e-41
Smith-Waterman score: 626; 39.1% identity (68.8% similar) in 276 aa overlap (9-282:6-273)
10 20 30 40 50 60
pF1KE1 MRGMKLLGALLALAALLQGAVSLKIAAFNIQTFGETKMSNATLVSYIVQILSRYDIALVQ
::: : : .:: ...: ::: : . .:.. ... .:.::.: :: ..:
CCDS14 MHYPTALLFLI-LANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQ
10 20 30 40 50
70 80 90 100 110
pF1KE1 EVRDSHLTAVGKLLDNLNQ-DAPDTYHYVVSEPLGRNSYKERYLFVYRPDQVSAVDSYYY
:: :: .:. :: .::. :. : . : :::..: : :.. :: ......:: :
CCDS14 EVVDSSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 DDGCEPCGNDTFNREPAIVRFFSRFTEVREFAIVPLHAAPGDAVAEIDALYDVYLDVQEK
.: .:.: ::: ...: . . ...::::..: . :..:::::.:.:...
CCDS14 NDE-----DDVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 WGLEDVMLMGDFNAGCSYVRPSQWSSIRLWTSPTFQWLIPDSADTTA-TPTHCAYDRIVV
: .::.:.::::: :. . .. ....: : : :.:.: :. :::. . :::.:::.:.
CCDS14 WQSKDVILLGDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVL
180 190 200 210 220 230
240 250 260 270 280
pF1KE1 AGMLLRGAVVPDSALPFNFQAAYGLSDQLAQAISDHYPVEVMLK
: :. . .: :.: ... :... : ::::::::: ::
CCDS14 HGERCRSLL--HTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLL
240 250 260 270 280
CCDS14 LLSLLSPQLCPAA
290 300
>>CCDS42105.1 DNASE1L2 gene_id:1775|Hs108|chr16 (299 aa)
initn: 898 init1: 556 opt: 556 Z-score: 755.6 bits: 147.8 E(32554): 9.1e-36
Smith-Waterman score: 916; 51.2% identity (73.4% similar) in 297 aa overlap (6-282:7-296)
10 20 30 40 50
pF1KE1 MRGMKLLGALLALAALLQGAVSLKIAAFNIQTFGETKMSNATLVSYIVQILSRYDIALV
::.:: :: : :...:.:.:::::.::..:.:. . : :..::. ::.:::
CCDS42 MGGPRALLAALWALEA--AGTAALRIGAFNIQSFGDSKVSDPACGSIIAKILAGYDLALV
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 QEVRDSHLTAVGKLLDNLNQDAPDTYHYVVSEPLGRNSYKERYLFVYRPDQVSAVDSYYY
::::: :.::. :....:. . : .: :.::::..::: :::::: : ::.::.: :
CCDS42 QEVRDPDLSAVSALMEQINSVSEHEYSFVSSQPLGRDQYKEMYLFVYRKDAVSVVDTYLY
60 70 80 90 100 110
120 130 140 150
pF1KE1 DDGCEPCGNDTFNREPAIVRFFSRFTEVR--------------------EFAIVPLHAAP
: : .:.:.::: .:.: . : : .....::::::
CCDS42 PD---P--EDVFSREPFVVKFSAPGTGERAPPLPSRRALTPPPLPAAAQNLVLIPLHAAP
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE1 GDAVAEIDALYDVYLDVQEKWGLEDVMLMGDFNAGCSYVRPSQWSSIRLWTSPTFQWLIP
.::::::::::::::: .::: .:....::::: ::::: ..:..::: .: .:.::::
CCDS42 HQAVAEIDALYDVYLDVIDKWGTDDMLFLGDFNADCSYVRAQDWAAIRLRSSEVFKWLIP
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE1 DSADTTATPTHCAYDRIVVAGMLLRGAVVPDSALPFNFQAAYGLSDQLAQAISDHYPVEV
::::::. . :::::::. : :: .. :.:: .:: .::.. : :::::.::::
CCDS42 DSADTTVGNSDCAYDRIVACGARLRRSLKPQSATVHDFQEEFGLDQTQALAISDHFPVEV
240 250 260 270 280 290
280
pF1KE1 MLK
::
CCDS42 TLKFHR
>>CCDS58836.1 DNASE1L3 gene_id:1776|Hs108|chr3 (275 aa)
initn: 694 init1: 364 opt: 547 Z-score: 744.0 bits: 145.5 E(32554): 4.1e-35
Smith-Waterman score: 644; 40.1% identity (65.3% similar) in 277 aa overlap (7-282:5-252)
10 20 30 40 50 60
pF1KE1 MRGMKLLGALLALAALLQGAVSLKIAAFNIQTFGETKMSNATLVSYIVQILSRYDIALVQ
:. :: : ...:....: .::...:::.:. . . .. ::....: :: ::.
CCDS58 MSRELAPLLLLLLSIHSALAMRICSFNVRSFGESKQEDKNAMDVIVKVIKRCDIILVM
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 EVRDSHLTAVGKLLDNLNQDAPDTYHYVVSEPLGRNSYKERYLFVYRPDQVSAVDSYYYD
:..::. :...:: .:. . : : ::.:
CCDS58 EIKDSNNRICPILMEKLN--------------------REKLVSVKR--------SYHYH
60 70 80 90
130 140 150 160 170 180
pF1KE1 DGCEPCGNDTFNREPAIVRFFSRFTEVREFAIVPLHAAPGDAVAEIDALYDVYLDVQEKW
: . :.:.::: .: : : : :..:.:.:::..: .: ::: : .:: ::...:
CCDS58 DY-QDGDADVFSREPFVVWFQSPHTAVKDFVIIPLHTTPETSVKEIDELVEVYTDVKHRW
100 110 120 130 140
190 200 210 220 230
pF1KE1 GLEDVMLMGDFNAGCSYVRPSQWSSIRLWTSPTFQWLIPDSADTTATP-THCAYDRIVVA
:. ..::::::::::: . :..::: :.: : ::: :. :::. :.:::::::.
CCDS58 KAENFIFMGDFNAGCSYVPKKAWKNIRLRTDPRFVWLIGDQEDTTVKKSTNCAYDRIVLR
150 160 170 180 190 200
240 250 260 270 280
pF1KE1 GMLLRGAVVPDSALPFNFQAAYGLSDQLAQAISDHYPVEVMLK
:. . ..::: : :.:: :: :... : .:::.::: :.
CCDS58 GQEIVSSVVPKSNSVFDFQKAYKLTEEEALDVSDHFPVEFKLQSSRAFTNSKKSVTLRKK
210 220 230 240 250 260
CCDS58 TKSKRS
270
282 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:31:13 2016 done: Sun Nov 6 22:31:13 2016
Total Scan time: 2.310 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]