Result of FASTA (omim) for
pFN21AB6792
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6792, 155 aa
1>>>pF1KB6792 155 - 155 aa - 155 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0325+/-0.000325; mu= 13.1385+/- 0.020
mean_var=57.7105+/-12.075, 0's: 0 Z-trim(116.3): 29 B-trim: 1604 in 1/51
Lambda= 0.168829
statistics sampled from 27289 (27318) to 27289 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.32), width: 16
Scan time: 5.460
The best scores are: opt bits E(85289)
NP_036407 (OMIM: 605507,614204) interleukin-36 rec ( 155) 1060 265.8 1.9e-71
NP_775262 (OMIM: 605507,614204) interleukin-36 rec ( 155) 1060 265.8 1.9e-71
XP_011509423 (OMIM: 137215,147679,612628,612852) P ( 143) 414 108.5 4.2e-24
NP_001305843 (OMIM: 137215,147679,612628,612852) i ( 143) 414 108.5 4.2e-24
XP_005263718 (OMIM: 137215,147679,612628,612852) P ( 143) 414 108.5 4.2e-24
NP_776215 (OMIM: 137215,147679,612628,612852) inte ( 143) 414 108.5 4.2e-24
NP_000568 (OMIM: 137215,147679,612628,612852) inte ( 159) 414 108.5 4.6e-24
NP_776214 (OMIM: 137215,147679,612628,612852) inte ( 177) 414 108.5 5.1e-24
NP_776213 (OMIM: 137215,147679,612628,612852) inte ( 180) 414 108.5 5.1e-24
NP_775184 (OMIM: 615296) interleukin-1 family memb ( 152) 365 96.5 1.7e-20
NP_115945 (OMIM: 615296) interleukin-1 family memb ( 152) 365 96.5 1.7e-20
NP_775270 (OMIM: 605508) interleukin-36 beta isofo ( 157) 260 71.0 8.9e-13
XP_011509264 (OMIM: 605508) PREDICTED: interleukin ( 157) 260 71.0 8.9e-13
XP_016859295 (OMIM: 605509) PREDICTED: interleukin ( 158) 245 67.3 1.1e-11
XP_011509267 (OMIM: 605509) PREDICTED: interleukin ( 158) 245 67.3 1.1e-11
XP_005263696 (OMIM: 605509) PREDICTED: interleukin ( 158) 245 67.3 1.1e-11
NP_055255 (OMIM: 605509) interleukin-36 alpha [Hom ( 158) 245 67.3 1.1e-11
NP_001265497 (OMIM: 605542) interleukin-36 gamma i ( 134) 230 63.6 1.2e-10
NP_062564 (OMIM: 605542) interleukin-36 gamma isof ( 169) 230 63.7 1.5e-10
NP_775297 (OMIM: 605510) interleukin-37 isoform 5 ( 192) 229 63.5 2e-10
NP_775294 (OMIM: 605510) interleukin-37 isoform 2 ( 197) 229 63.5 2e-10
XP_011509265 (OMIM: 605510) PREDICTED: interleukin ( 218) 229 63.5 2.2e-10
NP_055254 (OMIM: 605510) interleukin-37 isoform 1 ( 218) 229 63.5 2.2e-10
NP_775295 (OMIM: 605510) interleukin-37 isoform 3 ( 157) 213 59.5 2.5e-09
XP_011509266 (OMIM: 605510) PREDICTED: interleukin ( 178) 213 59.6 2.8e-09
NP_775296 (OMIM: 605510) interleukin-37 isoform 4 ( 178) 213 59.6 2.8e-09
XP_016859477 (OMIM: 137215,147720) PREDICTED: inte ( 238) 157 46.0 4.5e-05
NP_000567 (OMIM: 137215,147720) interleukin-1 beta ( 269) 157 46.0 5e-05
>>NP_036407 (OMIM: 605507,614204) interleukin-36 recepto (155 aa)
initn: 1060 init1: 1060 opt: 1060 Z-score: 1403.5 bits: 265.8 E(85289): 1.9e-71
Smith-Waterman score: 1060; 100.0% identity (100.0% similar) in 155 aa overlap (1-155:1-155)
10 20 30 40 50 60
pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSPVILG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSPVILG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VQGGSQCLSCGVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYPGWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VQGGSQCLSCGVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYPGWF
70 80 90 100 110 120
130 140 150
pF1KB6 LCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
:::::::::::::::::::::::::::::::::::
NP_036 LCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
130 140 150
>>NP_775262 (OMIM: 605507,614204) interleukin-36 recepto (155 aa)
initn: 1060 init1: 1060 opt: 1060 Z-score: 1403.5 bits: 265.8 E(85289): 1.9e-71
Smith-Waterman score: 1060; 100.0% identity (100.0% similar) in 155 aa overlap (1-155:1-155)
10 20 30 40 50 60
pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSPVILG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSPVILG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VQGGSQCLSCGVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYPGWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 VQGGSQCLSCGVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYPGWF
70 80 90 100 110 120
130 140 150
pF1KB6 LCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
:::::::::::::::::::::::::::::::::::
NP_775 LCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
130 140 150
>>XP_011509423 (OMIM: 137215,147679,612628,612852) PREDI (143 aa)
initn: 410 init1: 242 opt: 414 Z-score: 553.7 bits: 108.5 E(85289): 4.2e-24
Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (9-153:4-141)
10 20 30 40 50
pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSP--VI
::. : :..::.::::.:: :.. .: :.:.::: . : ..
XP_011 MQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVP-------IEPHALF
10 20 30 40
60 70 80 90 100 110
pF1KB6 LGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYP
::..::..:::: :.: : :: ::: .: . :..: :.: : : : :.:::::: :
XP_011 LGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFESAACP
50 60 70 80 90 100
120 130 140 150
pF1KB6 GWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
::::::. :::::: ::..:..: . .: ::::.
XP_011 GWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE
110 120 130 140
>>NP_001305843 (OMIM: 137215,147679,612628,612852) inter (143 aa)
initn: 410 init1: 242 opt: 414 Z-score: 553.7 bits: 108.5 E(85289): 4.2e-24
Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (9-153:4-141)
10 20 30 40 50
pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSP--VI
::. : :..::.::::.:: :.. .: :.:.::: . : ..
NP_001 MQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVP-------IEPHALF
10 20 30 40
60 70 80 90 100 110
pF1KB6 LGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYP
::..::..:::: :.: : :: ::: .: . :..: :.: : : : :.:::::: :
NP_001 LGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFESAACP
50 60 70 80 90 100
120 130 140 150
pF1KB6 GWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
::::::. :::::: ::..:..: . .: ::::.
NP_001 GWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE
110 120 130 140
>>XP_005263718 (OMIM: 137215,147679,612628,612852) PREDI (143 aa)
initn: 410 init1: 242 opt: 414 Z-score: 553.7 bits: 108.5 E(85289): 4.2e-24
Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (9-153:4-141)
10 20 30 40 50
pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSP--VI
::. : :..::.::::.:: :.. .: :.:.::: . : ..
XP_005 MQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVP-------IEPHALF
10 20 30 40
60 70 80 90 100 110
pF1KB6 LGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYP
::..::..:::: :.: : :: ::: .: . :..: :.: : : : :.:::::: :
XP_005 LGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFESAACP
50 60 70 80 90 100
120 130 140 150
pF1KB6 GWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
::::::. :::::: ::..:..: . .: ::::.
XP_005 GWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE
110 120 130 140
>>NP_776215 (OMIM: 137215,147679,612628,612852) interleu (143 aa)
initn: 410 init1: 242 opt: 414 Z-score: 553.7 bits: 108.5 E(85289): 4.2e-24
Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (9-153:4-141)
10 20 30 40 50
pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSP--VI
::. : :..::.::::.:: :.. .: :.:.::: . : ..
NP_776 MQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVP-------IEPHALF
10 20 30 40
60 70 80 90 100 110
pF1KB6 LGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYP
::..::..:::: :.: : :: ::: .: . :..: :.: : : : :.:::::: :
NP_776 LGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFESAACP
50 60 70 80 90 100
120 130 140 150
pF1KB6 GWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
::::::. :::::: ::..:..: . .: ::::.
NP_776 GWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE
110 120 130 140
>>NP_000568 (OMIM: 137215,147679,612628,612852) interleu (159 aa)
initn: 410 init1: 242 opt: 414 Z-score: 553.0 bits: 108.5 E(85289): 4.6e-24
Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (9-153:20-157)
10 20 30 40
pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRW
::. : :..::.::::.:: :.. .: :.:.:::
NP_000 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVP---
10 20 30 40 50
50 60 70 80 90 100
pF1KB6 LDASLSP--VILGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMG
. : ..::..::..:::: :.: : :: ::: .: . :..: :.: : : :
NP_000 ----IEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSG
60 70 80 90 100 110
110 120 130 140 150
pF1KB6 LTSSFESAAYPGWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
:.:::::: :::::::. :::::: ::..:..: . .: ::::.
NP_000 PTTSFESAACPGWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE
120 130 140 150
>>NP_776214 (OMIM: 137215,147679,612628,612852) interleu (177 aa)
initn: 410 init1: 242 opt: 414 Z-score: 552.3 bits: 108.5 E(85289): 5.1e-24
Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (9-153:38-175)
10 20 30
pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIK
::. : :..::.::::.:: :.. .:
NP_776 RSHLITLLLFLFHSETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 GEEISVVPNRWLDASLSP--VILGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKES
:.:.::: . : ..::..::..:::: :.: : :: ::: .: . :..
NP_776 EEKIDVVP-------IEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQD
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB6 KSFTFYRRDMGLTSSFESAAYPGWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
: :.: : : : :.:::::: :::::::. :::::: ::..:..: . .: ::::.
NP_776 KRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE
130 140 150 160 170
>>NP_776213 (OMIM: 137215,147679,612628,612852) interleu (180 aa)
initn: 410 init1: 242 opt: 414 Z-score: 552.2 bits: 108.5 E(85289): 5.1e-24
Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (9-153:41-178)
10 20 30
pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIK
::. : :..::.::::.:: :.. .:
NP_776 GGGGGEGEDNADSKETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNL
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB6 GEEISVVPNRWLDASLSP--VILGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKES
:.:.::: . : ..::..::..:::: :.: : :: ::: .: . :..
NP_776 EEKIDVVP-------IEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQD
80 90 100 110 120
100 110 120 130 140 150
pF1KB6 KSFTFYRRDMGLTSSFESAAYPGWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
: :.: : : : :.:::::: :::::::. :::::: ::..:..: . .: ::::.
NP_776 KRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE
130 140 150 160 170 180
>>NP_775184 (OMIM: 615296) interleukin-1 family member 1 (152 aa)
initn: 342 init1: 210 opt: 365 Z-score: 488.8 bits: 96.5 E(85289): 1.7e-20
Smith-Waterman score: 365; 43.8% identity (68.8% similar) in 144 aa overlap (11-153:12-150)
10 20 30 40 50
pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSPVIL
.: . :.:: ...:::.: : . .:.: ..::: : . :..:
NP_775 MCSLPMARYYIIKYADQKALYTRDGQLLVGDPVADNCC-AEKICILPNRGLARTKVPIFL
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 GVQGGSQCLSCGVGQE-PTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYPG
:.::::.::.: .: :.: :: ::: ::: :..:. :::.. . : . .:.::.::
NP_775 GIQGGSRCLACVETEEGPSLQLEDVNIEELYKGGEEATRFTFFQSSSGSAFRLEAAAWPG
60 70 80 90 100 110
120 130 140 150
pF1KB6 WFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
:::: : .:::.::. : .. : :::.:
NP_775 WFLCGPAEPQQPVQLTKESEPSAR----TKFYFEQSW
120 130 140 150
155 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:18:11 2016 done: Sat Nov 5 18:18:12 2016
Total Scan time: 5.460 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]