Result of FASTA (omim) for
pFN21AE4343
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4343, 354 aa
1>>>pF1KE4343 354 - 354 aa - 354 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2632+/-0.000392; mu= 17.1800+/- 0.024
mean_var=74.3418+/-14.803, 0's: 0 Z-trim(113.9): 72 B-trim: 677 in 2/50
Lambda= 0.148750
statistics sampled from 23426 (23498) to 23426 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.657), E-opt: 0.2 (0.276), width: 16
Scan time: 7.970
The best scores are: opt bits E(85289)
NP_001209 (OMIM: 143860,603263) carbonic anhydrase ( 354) 2377 519.4 4.7e-147
NP_996808 (OMIM: 143860,603263) carbonic anhydrase ( 343) 1988 435.9 6.1e-122
NP_001280571 (OMIM: 143860,603263) carbonic anhydr ( 283) 1340 296.8 3.8e-80
NP_036245 (OMIM: 604832) carbonic anhydrase 14 pre ( 337) 916 205.9 1.1e-52
XP_005245116 (OMIM: 604832) PREDICTED: carbonic an ( 336) 914 205.4 1.5e-52
XP_005245117 (OMIM: 604832) PREDICTED: carbonic an ( 319) 863 194.5 2.8e-49
XP_006711322 (OMIM: 604832) PREDICTED: carbonic an ( 318) 862 194.3 3.2e-49
XP_011507681 (OMIM: 604832) PREDICTED: carbonic an ( 323) 761 172.6 1.1e-42
XP_006711324 (OMIM: 604832) PREDICTED: carbonic an ( 281) 748 169.8 6.7e-42
XP_016856382 (OMIM: 604832) PREDICTED: carbonic an ( 263) 695 158.4 1.7e-38
NP_001207 (OMIM: 603179) carbonic anhydrase 9 prec ( 459) 692 157.9 4.1e-38
XP_011540385 (OMIM: 114780) PREDICTED: carbonic an ( 294) 674 153.9 4.2e-37
NP_001206 (OMIM: 114780) carbonic anhydrase 6 isof ( 308) 650 148.8 1.5e-35
NP_001257429 (OMIM: 114780) carbonic anhydrase 6 i ( 313) 650 148.8 1.6e-35
XP_011540386 (OMIM: 114780) PREDICTED: carbonic an ( 324) 650 148.8 1.6e-35
NP_005173 (OMIM: 114770) carbonic anhydrase 7 isof ( 264) 585 134.8 2.2e-31
NP_940986 (OMIM: 611436) carbonic anhydrase 13 [Ho ( 262) 571 131.8 1.7e-30
NP_001122303 (OMIM: 114800) carbonic anhydrase 1 i ( 261) 570 131.5 2e-30
NP_001158302 (OMIM: 114800) carbonic anhydrase 1 i ( 261) 570 131.5 2e-30
NP_001122302 (OMIM: 114800) carbonic anhydrase 1 i ( 261) 570 131.5 2e-30
NP_001729 (OMIM: 114800) carbonic anhydrase 1 isof ( 261) 570 131.5 2e-30
NP_001122301 (OMIM: 114800) carbonic anhydrase 1 i ( 261) 570 131.5 2e-30
XP_005265410 (OMIM: 176886) PREDICTED: receptor-ty (1416) 557 129.3 5.2e-29
NP_002832 (OMIM: 176886) receptor-type tyrosine-pr (1445) 557 129.3 5.3e-29
NP_000058 (OMIM: 259730,611492) carbonic anhydrase ( 260) 544 126.0 9.5e-29
NP_005172 (OMIM: 114750) carbonic anhydrase 3 [Hom ( 260) 542 125.5 1.3e-28
NP_001193768 (OMIM: 176891,600263) receptor-type t (1448) 543 126.3 4.2e-28
NP_001193767 (OMIM: 176891,600263) receptor-type t (1455) 543 126.3 4.2e-28
XP_016867966 (OMIM: 176891,600263) PREDICTED: rece (2301) 543 126.4 6.1e-28
XP_005250576 (OMIM: 176891,600263) PREDICTED: rece (2308) 543 126.4 6.1e-28
NP_002842 (OMIM: 176891,600263) receptor-type tyro (2315) 543 126.4 6.1e-28
XP_011521613 (OMIM: 114770) PREDICTED: carbonic an ( 242) 518 120.4 4.3e-27
XP_016856384 (OMIM: 604832) PREDICTED: carbonic an ( 244) 511 118.9 1.2e-26
XP_016856383 (OMIM: 604832) PREDICTED: carbonic an ( 262) 511 118.9 1.3e-26
NP_000708 (OMIM: 114760,600852) carbonic anhydrase ( 312) 502 117.0 5.7e-26
NP_004047 (OMIM: 114815,613227) carbonic anhydrase ( 290) 498 116.1 9.7e-26
NP_001308766 (OMIM: 114815,613227) carbonic anhydr ( 290) 498 116.1 9.7e-26
XP_011521614 (OMIM: 114770) PREDICTED: carbonic an ( 208) 482 112.6 8.1e-25
NP_001014435 (OMIM: 114770) carbonic anhydrase 7 i ( 208) 482 112.6 8.1e-25
XP_005256193 (OMIM: 114770) PREDICTED: carbonic an ( 208) 482 112.6 8.1e-25
NP_001308767 (OMIM: 114815,613227) carbonic anhydr ( 263) 477 111.6 2e-24
NP_001257430 (OMIM: 114780) carbonic anhydrase 6 i ( 248) 472 110.5 4.1e-24
NP_001730 (OMIM: 114761,615751) carbonic anhydrase ( 305) 456 107.1 5.2e-23
XP_016862453 (OMIM: 176886) PREDICTED: receptor-ty (1329) 448 105.9 5.4e-22
NP_001278896 (OMIM: 114800) carbonic anhydrase 1 i ( 195) 436 102.7 7.2e-22
NP_001076002 (OMIM: 604642) carbonic anhydrase-rel ( 328) 436 102.9 1.1e-21
NP_001076003 (OMIM: 604642) carbonic anhydrase-rel ( 328) 436 102.9 1.1e-21
NP_064563 (OMIM: 604642) carbonic anhydrase-relate ( 328) 436 102.9 1.1e-21
XP_016884736 (OMIM: 300230) PREDICTED: carbonic an ( 278) 434 102.4 1.3e-21
XP_005274499 (OMIM: 300230) PREDICTED: carbonic an ( 317) 434 102.4 1.4e-21
>>NP_001209 (OMIM: 143860,603263) carbonic anhydrase 12 (354 aa)
initn: 2377 init1: 2377 opt: 2377 Z-score: 2761.1 bits: 519.4 E(85289): 4.7e-147
Smith-Waterman score: 2377; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:1-354)
10 20 30 40 50 60
pF1KE4 MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 HSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 HWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 PSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 NPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQVCTAAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQVCTAAGL
250 260 270 280 290 300
310 320 330 340 350
pF1KE4 SLGIILSLALAGILGICIVVVVSIWLFRRKSIKKGDNKGVIYKPATKMETEAHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLGIILSLALAGILGICIVVVVSIWLFRRKSIKKGDNKGVIYKPATKMETEAHA
310 320 330 340 350
>>NP_996808 (OMIM: 143860,603263) carbonic anhydrase 12 (343 aa)
initn: 1981 init1: 1981 opt: 1988 Z-score: 2310.2 bits: 435.9 E(85289): 6.1e-122
Smith-Waterman score: 2277; 96.9% identity (96.9% similar) in 354 aa overlap (1-354:1-343)
10 20 30 40 50 60
pF1KE4 MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 HSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 HSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 HWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 HWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 PSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 PSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 NPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQVCTAAGL
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 NPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQ---------
250 260 270 280 290
310 320 330 340 350
pF1KE4 SLGIILSLALAGILGICIVVVVSIWLFRRKSIKKGDNKGVIYKPATKMETEAHA
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 --GIILSLALAGILGICIVVVVSIWLFRRKSIKKGDNKGVIYKPATKMETEAHA
300 310 320 330 340
>>NP_001280571 (OMIM: 143860,603263) carbonic anhydrase (283 aa)
initn: 1551 init1: 1333 opt: 1340 Z-score: 1559.8 bits: 296.8 E(85289): 3.8e-80
Smith-Waterman score: 1731; 79.9% identity (79.9% similar) in 354 aa overlap (1-354:1-283)
10 20 30 40 50 60
pF1KE4 MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDL
:::::::::::::::::::::::::::::::::::
NP_001 MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYF-------------------------
10 20 30
70 80 90 100 110 120
pF1KE4 HSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHL
:::::::::::::::::::::::::
NP_001 -----------------------------------VKLNLPSDMHIQGLQSRYSATQLHL
40 50 60
130 140 150 160 170 180
pF1KE4 HWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFN
70 80 90 100 110 120
190 200 210 220 230 240
pF1KE4 PSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFR
130 140 150 160 170 180
250 260 270 280 290 300
pF1KE4 NPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQVCTAAGL
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQ---------
190 200 210 220 230
310 320 330 340 350
pF1KE4 SLGIILSLALAGILGICIVVVVSIWLFRRKSIKKGDNKGVIYKPATKMETEAHA
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --GIILSLALAGILGICIVVVVSIWLFRRKSIKKGDNKGVIYKPATKMETEAHA
240 250 260 270 280
>>NP_036245 (OMIM: 604832) carbonic anhydrase 14 precurs (337 aa)
initn: 832 init1: 517 opt: 916 Z-score: 1067.0 bits: 205.9 E(85289): 1.1e-52
Smith-Waterman score: 916; 43.4% identity (74.9% similar) in 327 aa overlap (29-352:19-337)
10 20 30 40 50 60
pF1KE4 MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDL
:..::: :: :.. : .:: ::. :::::.
NP_036 MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDI
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 HSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHL
..: . .: .: :. .::. ... . : ::::.:.:.::: ... :: .: :.::::
NP_036 QTDSVTFDPDLPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHL
60 70 80 90 100 110
130 140 150 160 170
pF1KE4 HWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMG-SF
:::. ..: :::: .... ::::::::.:: : . : :... .:::::..:::.: .
NP_036 HWGQKGSPGGSEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 NPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVF
: .:..:.:::..:..: :.. :: ::..::::.. ..:.:: :::::::: .::::::
NP_036 NIAYEHILSHLHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVF
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 RNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQVCTAAG
:::.::: :. .:. :. ..:: . ...:.: .: ...:.:..:: :. ...
NP_036 YRRSQISMEQLEKLQGTLFSTE-EEPS-KLLVQNYRALQPLNQRMVFASFIQA----GSS
240 250 260 270 280
300 310 320 330 340 350
pF1KE4 LSLGIILSLALAGILGICIVVVVSIWLFRRKSIKKG--DNKGVIYKPATKMETEAHA
. : .:::.. ::: :. ........ :: :: . :.:.. : . :::
NP_036 YTTGEMLSLGV-GILVGCLCLLLAVYFIARKIRKKRLENRKSVVFTSA-QATTEA
290 300 310 320 330
>>XP_005245116 (OMIM: 604832) PREDICTED: carbonic anhydr (336 aa)
initn: 832 init1: 517 opt: 914 Z-score: 1064.7 bits: 205.4 E(85289): 1.5e-52
Smith-Waterman score: 914; 43.4% identity (74.6% similar) in 327 aa overlap (29-352:19-336)
10 20 30 40 50 60
pF1KE4 MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDL
:..::: :: :.. : .:: ::. :::::.
XP_005 MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDI
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 HSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHL
..: . .: .: :. .::. ... . : ::::.:.:.::: ... :: .: :.::::
XP_005 QTDSVTFDPDLPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHL
60 70 80 90 100 110
130 140 150 160 170
pF1KE4 HWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMG-SF
:::. ..: :::: .... ::::::::.:: : . : :... .:::::..:::.: .
XP_005 HWGQKGSPGGSEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 NPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVF
: .:..:.:::..:..: :.. :: ::..::::.. ..:.:: :::::::: .::::::
XP_005 NIAYEHILSHLHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVF
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 RNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQVCTAAG
:::.::: :. .:. :. ..:: . ...:.: .: ...:.:..:: : ...
XP_005 YRRSQISMEQLEKLQGTLFSTE-EEPS-KLLVQNYRALQPLNQRMVFASFIQ-----GSS
240 250 260 270 280
300 310 320 330 340 350
pF1KE4 LSLGIILSLALAGILGICIVVVVSIWLFRRKSIKKG--DNKGVIYKPATKMETEAHA
. : .:::.. ::: :. ........ :: :: . :.:.. : . :::
XP_005 YTTGEMLSLGV-GILVGCLCLLLAVYFIARKIRKKRLENRKSVVFTSA-QATTEA
290 300 310 320 330
>>XP_005245117 (OMIM: 604832) PREDICTED: carbonic anhydr (319 aa)
initn: 774 init1: 517 opt: 863 Z-score: 1005.8 bits: 194.5 E(85289): 2.8e-49
Smith-Waterman score: 863; 46.0% identity (76.8% similar) in 272 aa overlap (29-299:19-288)
10 20 30 40 50 60
pF1KE4 MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDL
:..::: :: :.. : .:: ::. :::::.
XP_005 MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDI
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 HSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHL
..: . .: .: :. .::. ... . : ::::.:.:.::: ... :: .: :.::::
XP_005 QTDSVTFDPDLPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHL
60 70 80 90 100 110
130 140 150 160 170
pF1KE4 HWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMG-SF
:::. ..: :::: .... ::::::::.:: : . : :... .:::::..:::.: .
XP_005 HWGQKGSPGGSEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 NPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVF
: .:..:.:::..:..: :.. :: ::..::::.. ..:.:: :::::::: .::::::
XP_005 NIAYEHILSHLHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVF
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 RNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQVCTAAG
:::.::: :. .:. :. ..:: . ...:.: .: ...:.:..:: :. ..:
XP_005 YRRSQISMEQLEKLQGTLFSTE-EEPS-KLLVQNYRALQPLNQRMVFASFIQAGSSYTTG
240 250 260 270 280
300 310 320 330 340 350
pF1KE4 LSLGIILSLALAGILGICIVVVVSIWLFRRKSIKKGDNKGVIYKPATKMETEAHA
XP_005 RRGWKTERVWSSPQHKPRLRHKFLLRYHGCG
290 300 310
>>XP_006711322 (OMIM: 604832) PREDICTED: carbonic anhydr (318 aa)
initn: 774 init1: 517 opt: 862 Z-score: 1004.7 bits: 194.3 E(85289): 3.2e-49
Smith-Waterman score: 862; 47.0% identity (77.7% similar) in 264 aa overlap (29-291:19-280)
10 20 30 40 50 60
pF1KE4 MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDL
:..::: :: :.. : .:: ::. :::::.
XP_006 MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDI
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 HSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHL
..: . .: .: :. .::. ... . : ::::.:.:.::: ... :: .: :.::::
XP_006 QTDSVTFDPDLPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHL
60 70 80 90 100 110
130 140 150 160 170
pF1KE4 HWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMG-SF
:::. ..: :::: .... ::::::::.:: : . : :... .:::::..:::.: .
XP_006 HWGQKGSPGGSEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 NPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVF
: .:..:.:::..:..: :.. :: ::..::::.. ..:.:: :::::::: .::::::
XP_006 NIAYEHILSHLHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVF
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 RNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQVCTAAG
:::.::: :. .:. :. ..:: . ...:.: .: ...:.:..:: :
XP_006 YRRSQISMEQLEKLQGTLFSTE-EEPS-KLLVQNYRALQPLNQRMVFASFIQGSSYTTGR
240 250 260 270 280
300 310 320 330 340 350
pF1KE4 LSLGIILSLALAGILGICIVVVVSIWLFRRKSIKKGDNKGVIYKPATKMETEAHA
XP_006 RGWKTERVWSSPQHKPRLRHKFLLRYHGCG
290 300 310
>>XP_011507681 (OMIM: 604832) PREDICTED: carbonic anhydr (323 aa)
initn: 664 init1: 349 opt: 761 Z-score: 887.5 bits: 172.6 E(85289): 1.1e-42
Smith-Waterman score: 761; 39.8% identity (71.3% similar) in 324 aa overlap (32-352:12-323)
10 20 30 40 50 60
pF1KE4 PRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDLH
: .. :: . :. . . . ..:. :
XP_011 MLFSALLLEVIWI-LAADGGQHWTYEGEQISRPPDNPFTLG
10 20 30 40
70 80 90 100 110 120
pF1KE4 SDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLH
: .. : .::. ... . : ::::.:.:.::: ... :: .: :.:::::
XP_011 PPHLAGRHTVRP---HGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHLH
50 60 70 80 90
130 140 150 160 170 180
pF1KE4 WGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMG-SFN
::. ..: :::: .... ::::::::.:: : . : :... .:::::..:::.: . :
XP_011 WGQKGSPGGSEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE4 PSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFR
.:..:.:::..:..: :.. :: ::..::::.. ..:.:: :::::::: .::::::
XP_011 IAYEHILSHLHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFY
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE4 NPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQVCTAAGL
:::.::: :. .:. :. ..:: . ...:.: .: ...:.:..:: :. ...
XP_011 RRSQISMEQLEKLQGTLFSTE-EEPS-KLLVQNYRALQPLNQRMVFASFIQA----GSSY
220 230 240 250 260 270
310 320 330 340 350
pF1KE4 SLGIILSLALAGILGICIVVVVSIWLFRRKSIKKG--DNKGVIYKPATKMETEAHA
. : .:::.. ::: :. ........ :: :: . :.:.. : . :::
XP_011 TTGEMLSLGV-GILVGCLCLLLAVYFIARKIRKKRLENRKSVVFTSA-QATTEA
280 290 300 310 320
>>XP_006711324 (OMIM: 604832) PREDICTED: carbonic anhydr (281 aa)
initn: 664 init1: 349 opt: 748 Z-score: 873.2 bits: 169.8 E(85289): 6.7e-42
Smith-Waterman score: 748; 43.4% identity (75.6% similar) in 279 aa overlap (77-352:11-281)
50 60 70 80 90 100
pF1KE4 YPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHI
.::. ... . : ::::.:.:.::: ...
XP_006 MGVNTGRMRPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYL
10 20 30 40
110 120 130 140 150 160
pF1KE4 QGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEG
:: .: :.:::::::. ..: :::: .... ::::::::.:: : . : :... .:
XP_006 GGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQG
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE4 LAVLAVLIEMG-SFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSL
::::..:::.: . : .:..:.:::..:..: :.. :: ::..::::.. ..:.:: :::
XP_006 LAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSL
110 120 130 140 150 160
230 240 250 260 270 280
pF1KE4 TTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLV
::::: .:::::: :::.::: :. .:. :. ..:: . ...:.: .: ...:.:
XP_006 TTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTE-EEPS-KLLVQNYRALQPLNQRMV
170 180 190 200 210
290 300 310 320 330 340
pF1KE4 YTSFSQVQVCTAAGLSLGIILSLALAGILGICIVVVVSIWLFRRKSIKKG--DNKGVIYK
..:: : .... . : .:::.. ::: :. ........ :: :: . :.:..
XP_006 FASFIQ----AGSSYTTGEMLSLGV-GILVGCLCLLLAVYFIARKIRKKRLENRKSVVFT
220 230 240 250 260 270
350
pF1KE4 PATKMETEAHA
: . :::
XP_006 SA-QATTEA
280
>>XP_016856382 (OMIM: 604832) PREDICTED: carbonic anhydr (263 aa)
initn: 606 init1: 349 opt: 695 Z-score: 812.2 bits: 158.4 E(85289): 1.7e-38
Smith-Waterman score: 695; 46.4% identity (78.1% similar) in 224 aa overlap (77-299:11-232)
50 60 70 80 90 100
pF1KE4 YPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHI
.::. ... . : ::::.:.:.::: ...
XP_016 MGVNTGRMRPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYL
10 20 30 40
110 120 130 140 150 160
pF1KE4 QGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEG
:: .: :.:::::::. ..: :::: .... ::::::::.:: : . : :... .:
XP_016 GGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQG
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE4 LAVLAVLIEMG-SFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSL
::::..:::.: . : .:..:.:::..:..: :.. :: ::..::::.. ..:.:: :::
XP_016 LAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSL
110 120 130 140 150 160
230 240 250 260 270 280
pF1KE4 TTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLV
::::: .:::::: :::.::: :. .:. :. ..:: . ...:.: .: ...:.:
XP_016 TTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTE-EEPS-KLLVQNYRALQPLNQRMV
170 180 190 200 210
290 300 310 320 330 340
pF1KE4 YTSFSQVQVCTAAGLSLGIILSLALAGILGICIVVVVSIWLFRRKSIKKGDNKGVIYKPA
..:: :. ..:
XP_016 FASFIQAGSSYTTGRRGWKTERVWSSPQHKPRLRHKFLLRYHGCG
220 230 240 250 260
354 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 02:10:56 2016 done: Sun Nov 6 02:10:57 2016
Total Scan time: 7.970 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]