Result of FASTA (omim) for
pFN21AE5124
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5124, 84 aa
1>>>pF1KE5124 84 - 84 aa - 84 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7234+/-0.000272; mu= 11.6397+/- 0.017
mean_var=62.4912+/-12.441, 0's: 0 Z-trim(119.8): 80 B-trim: 28 in 1/53
Lambda= 0.162243
statistics sampled from 34131 (34220) to 34131 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.783), E-opt: 0.2 (0.401), width: 16
Scan time: 3.630
The best scores are: opt bits E(85289)
NP_066937 (OMIM: 605753) serine protease inhibitor ( 84) 587 144.7 1.7e-35
NP_001258649 (OMIM: 605753) serine protease inhibi ( 119) 490 122.1 1.5e-28
NP_001258647 (OMIM: 605753) serine protease inhibi ( 134) 490 122.2 1.6e-28
XP_011532707 (OMIM: 605753) PREDICTED: serine prot ( 186) 393 99.6 1.4e-21
NP_003113 (OMIM: 167790,167800,608189) serine prot ( 79) 180 49.4 7.5e-07
NP_001035523 (OMIM: 613511) serine protease inhibi ( 86) 169 46.9 4.8e-06
NP_995313 (OMIM: 615868) serine protease inhibitor ( 80) 163 45.4 1.2e-05
NP_001182219 (OMIM: 615868) serine protease inhibi ( 80) 163 45.4 1.2e-05
NP_055286 (OMIM: 613929) serine protease inhibitor ( 86) 162 45.2 1.5e-05
XP_016865198 (OMIM: 613511) PREDICTED: serine prot ( 107) 157 44.1 3.9e-05
NP_001035218 (OMIM: 615205) serine protease inhibi ( 94) 143 40.8 0.00035
NP_006837 (OMIM: 147050,256500,605010) serine prot (1064) 145 42.1 0.0016
XP_011535853 (OMIM: 147050,256500,605010) PREDICTE (1066) 145 42.1 0.0016
NP_001121170 (OMIM: 147050,256500,605010) serine p (1094) 145 42.1 0.0016
XP_011539731 (OMIM: 103320,615120) PREDICTED: agri (2004) 140 41.2 0.0059
NP_940978 (OMIM: 103320,615120) agrin isoform 2 pr (2045) 140 41.2 0.006
XP_005244806 (OMIM: 103320,615120) PREDICTED: agri (2049) 140 41.2 0.006
NP_001292204 (OMIM: 103320,615120) agrin isoform 1 (2068) 140 41.2 0.006
>>NP_066937 (OMIM: 605753) serine protease inhibitor Kaz (84 aa)
initn: 587 init1: 587 opt: 587 Z-score: 758.5 bits: 144.7 E(85289): 1.7e-35
Smith-Waterman score: 587; 100.0% identity (100.0% similar) in 84 aa overlap (1-84:1-84)
10 20 30 40 50 60
pF1KE5 MALSVLRLALLLLAVTFAASLIPQFGLFSKYRTPNCSQYRLPGCPRHFNPVCGSDMSTYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MALSVLRLALLLLAVTFAASLIPQFGLFSKYRTPNCSQYRLPGCPRHFNPVCGSDMSTYA
10 20 30 40 50 60
70 80
pF1KE5 NECTLCMKIREGGHNIKIIRNGPC
::::::::::::::::::::::::
NP_066 NECTLCMKIREGGHNIKIIRNGPC
70 80
>>NP_001258649 (OMIM: 605753) serine protease inhibitor (119 aa)
initn: 578 init1: 490 opt: 490 Z-score: 633.7 bits: 122.1 E(85289): 1.5e-28
Smith-Waterman score: 490; 100.0% identity (100.0% similar) in 66 aa overlap (19-84:54-119)
10 20 30 40
pF1KE5 MALSVLRLALLLLAVTFAASLIPQFGLFSKYRTPNCSQYRLPGCPRHF
::::::::::::::::::::::::::::::
NP_001 GPGERGPPEKSGFGSQTGGGPCPAPGGLGDASLIPQFGLFSKYRTPNCSQYRLPGCPRHF
30 40 50 60 70 80
50 60 70 80
pF1KE5 NPVCGSDMSTYANECTLCMKIREGGHNIKIIRNGPC
::::::::::::::::::::::::::::::::::::
NP_001 NPVCGSDMSTYANECTLCMKIREGGHNIKIIRNGPC
90 100 110
>>NP_001258647 (OMIM: 605753) serine protease inhibitor (134 aa)
initn: 578 init1: 490 opt: 490 Z-score: 633.0 bits: 122.2 E(85289): 1.6e-28
Smith-Waterman score: 490; 100.0% identity (100.0% similar) in 66 aa overlap (19-84:69-134)
10 20 30 40
pF1KE5 MALSVLRLALLLLAVTFAASLIPQFGLFSKYRTPNCSQYRLPGCPRHF
::::::::::::::::::::::::::::::
NP_001 QTGGGPCPAPGGLGDGTRAPVTGGSPEDLPASLIPQFGLFSKYRTPNCSQYRLPGCPRHF
40 50 60 70 80 90
50 60 70 80
pF1KE5 NPVCGSDMSTYANECTLCMKIREGGHNIKIIRNGPC
::::::::::::::::::::::::::::::::::::
NP_001 NPVCGSDMSTYANECTLCMKIREGGHNIKIIRNGPC
100 110 120 130
>>XP_011532707 (OMIM: 605753) PREDICTED: serine protease (186 aa)
initn: 405 init1: 393 opt: 393 Z-score: 508.3 bits: 99.6 E(85289): 1.4e-21
Smith-Waterman score: 393; 100.0% identity (100.0% similar) in 51 aa overlap (34-84:136-186)
10 20 30 40 50 60
pF1KE5 SVLRLALLLLAVTFAASLIPQFGLFSKYRTPNCSQYRLPGCPRHFNPVCGSDMSTYANEC
::::::::::::::::::::::::::::::
XP_011 DRRGKTAGAGGGWRCRCCAWRCCSWQLPSQPNCSQYRLPGCPRHFNPVCGSDMSTYANEC
110 120 130 140 150 160
70 80
pF1KE5 TLCMKIREGGHNIKIIRNGPC
:::::::::::::::::::::
XP_011 TLCMKIREGGHNIKIIRNGPC
170 180
>>NP_003113 (OMIM: 167790,167800,608189) serine protease (79 aa)
initn: 184 init1: 167 opt: 180 Z-score: 244.0 bits: 49.4 E(85289): 7.5e-07
Smith-Waterman score: 180; 38.7% identity (65.3% similar) in 75 aa overlap (10-84:6-79)
10 20 30 40 50 60
pF1KE5 MALSVLRLALLLLAVTFAASLIPQFGLFSKYRTPNCSQYRLPGCPRHFNPVCGSDMSTYA
..::.. :: . : : : .: . .: :: . ..::::.: .::
NP_003 MKVTGIFLLSALALLSLSGNTGADSLGREAKCYN-ELNGCTKIYDPVCGTDGNTYP
10 20 30 40 50
70 80
pF1KE5 NECTLCMKIREGGHNIKIIRNGPC
:::.::.. :. .: : ..:::
NP_003 NECVLCFENRKRQTSILIQKSGPC
60 70
>>NP_001035523 (OMIM: 613511) serine protease inhibitor (86 aa)
initn: 146 init1: 119 opt: 169 Z-score: 229.6 bits: 46.9 E(85289): 4.8e-06
Smith-Waterman score: 169; 33.3% identity (66.7% similar) in 81 aa overlap (10-84:7-86)
10 20 30 40 50
pF1KE5 MALSVLRLALLLLAVTFAASLIPQFGLFSKYRTPNCSQYRL--PG----CPRHFNPVCGS
.::::.:.:. . . . .: . .::.:. :: : . ..:.:::
NP_001 MRATAIVLLLALTLATMFSIECAKQTK-QMVDCSHYKKLPPGQQRFCHHMYDPICGS
10 20 30 40 50
60 70 80
pF1KE5 DMSTYANECTLCMKIREGGHNIKIIRNGPC
: .:: :.: .: :... ..:... : :
NP_001 DGKTYKNDCFFCSKVKKTDGTLKFVHFGKC
60 70 80
>>NP_995313 (OMIM: 615868) serine protease inhibitor Kaz (80 aa)
initn: 120 init1: 105 opt: 163 Z-score: 222.4 bits: 45.4 E(85289): 1.2e-05
Smith-Waterman score: 163; 32.1% identity (66.7% similar) in 81 aa overlap (6-84:1-80)
10 20 30 40 50
pF1KE5 MALSVLRLALLLLAVTFAASLIPQFGLFSKYRTPNCSQYRLPG--CPRHFNPVCGSDMST
..:. ..: ...: . :.::. .:.... : : :. :: :::: .:
NP_995 MKLSGMFLLLSLAL-FCFLTGVFSQGGQVDCGEFQDPKVYCTRESNPHCGSDGQT
10 20 30 40 50
60 70 80
pF1KE5 YANECTLCMKIREGGHNIKIIRNGPC
:.:.:..: : ..: .:.. . : :
NP_995 YGNKCAFCKAIVKSGGKISLKHPGKC
60 70 80
>>NP_001182219 (OMIM: 615868) serine protease inhibitor (80 aa)
initn: 120 init1: 105 opt: 163 Z-score: 222.4 bits: 45.4 E(85289): 1.2e-05
Smith-Waterman score: 163; 32.1% identity (66.7% similar) in 81 aa overlap (6-84:1-80)
10 20 30 40 50
pF1KE5 MALSVLRLALLLLAVTFAASLIPQFGLFSKYRTPNCSQYRLPG--CPRHFNPVCGSDMST
..:. ..: ...: . :.::. .:.... : : :. :: :::: .:
NP_001 MKLSGMFLLLSLAL-FCFLTGVFSQGGQVDCGEFQDPKVYCTRESNPHCGSDGQT
10 20 30 40 50
60 70 80
pF1KE5 YANECTLCMKIREGGHNIKIIRNGPC
:.:.:..: : ..: .:.. . : :
NP_001 YGNKCAFCKAIVKSGGKISLKHPGKC
60 70 80
>>NP_055286 (OMIM: 613929) serine protease inhibitor Kaz (86 aa)
initn: 121 init1: 89 opt: 162 Z-score: 220.7 bits: 45.2 E(85289): 1.5e-05
Smith-Waterman score: 162; 33.7% identity (57.0% similar) in 86 aa overlap (1-84:1-86)
10 20 30 40 50
pF1KE5 MALSVLRLALLLLAVTFAASLIP-QFGLFSKYRTPNCSQY-RLPGCPRHFNPVCGSDMST
::. .:: : :. . .: : . : : : .. . : : . : :::.: :
NP_055 MAVRQWVIALALAALLVVDREVPVAAGKLPFSRMPICEHMVESPTCSQMSNLVCGTDGLT
10 20 30 40 50 60
60 70 80
pF1KE5 YANECTLCMKIREGGHNIKIIRNGPC
:.::: ::. . ..:.:...: :
NP_055 YTNECQLCLARIKTKQDIQIMKDGKC
70 80
>>XP_016865198 (OMIM: 613511) PREDICTED: serine protease (107 aa)
initn: 113 init1: 89 opt: 157 Z-score: 213.1 bits: 44.1 E(85289): 3.9e-05
Smith-Waterman score: 157; 35.7% identity (67.9% similar) in 56 aa overlap (35-84:52-107)
10 20 30 40 50
pF1KE5 VLRLALLLLAVTFAASLIPQFGLFSKYRTPNCSQYRL--PG----CPRHFNPVCGSDMST
.::.:. :: : . ..:.:::: .:
XP_016 EHNEPRRLMGLTQPEHLQGIECAKQTKQMVDCSHYKKLPPGQQRFCHHMYDPICGSDGKT
30 40 50 60 70 80
60 70 80
pF1KE5 YANECTLCMKIREGGHNIKIIRNGPC
: :.: .: :... ..:... : :
XP_016 YKNDCFFCSKVKKTDGTLKFVHFGKC
90 100
84 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 21:37:58 2016 done: Mon Nov 7 21:37:58 2016
Total Scan time: 3.630 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]