FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6819, 162 aa
  1>>>pF1KB6819 162 - 162 aa - 162 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.7562+/-0.000367; mu= 14.7432+/- 0.023
 mean_var=53.5702+/-10.660, 0's: 0 Z-trim(112.9): 16  B-trim: 492 in 1/50
 Lambda= 0.175232
 statistics sampled from 21930 (21938) to 21930 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.64), E-opt: 0.2 (0.257), width:  16
 Scan time:  4.950

The best scores are:                                      opt bits E(85289)
NP_000576 (OMIM: 600554) interleukin-15 isoform 1  ( 162) 1054 274.1   7e-74
NP_751915 (OMIM: 600554) interleukin-15 isoform 2  ( 135)  806 211.3 4.5e-55
NP_068575 (OMIM: 605384,615767) interleukin-21 iso ( 162)  125 39.2  0.0035
NP_001193935 (OMIM: 605384,615767) interleukin-21  ( 153)  121 38.2  0.0067


>>NP_000576 (OMIM: 600554) interleukin-15 isoform 1 prep  (162 aa)
 initn: 1054 init1: 1054 opt: 1054  Z-score: 1447.4  bits: 274.1 E(85289): 7e-74
Smith-Waterman score: 1054; 100.0% identity (100.0% similar) in 162 aa overlap (1-162:1-162)

               10        20        30        40        50        60
pF1KB6 MRISKPHLRSISIQCYLCLLLNSHFLTEAGIHVFILGCFSAGLPKTEANWVNVISDLKKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MRISKPHLRSISIQCYLCLLLNSHFLTEAGIHVFILGCFSAGLPKTEANWVNVISDLKKI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 EDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILANN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILANN
               70        80        90       100       110       120

              130       140       150       160  
pF1KB6 SLSSNGNVTESGCKECEELEEKNIKEFLQSFVHIVQMFINTS
       ::::::::::::::::::::::::::::::::::::::::::
NP_000 SLSSNGNVTESGCKECEELEEKNIKEFLQSFVHIVQMFINTS
              130       140       150       160  

>>NP_751915 (OMIM: 600554) interleukin-15 isoform 2 prep  (135 aa)
 initn: 806 init1: 806 opt: 806  Z-score: 1109.8  bits: 211.3 E(85289): 4.5e-55
Smith-Waterman score: 806; 100.0% identity (100.0% similar) in 125 aa overlap (38-162:11-135)

        10        20        30        40        50        60       
pF1KB6 LRSISIQCYLCLLLNSHFLTEAGIHVFILGCFSAGLPKTEANWVNVISDLKKIEDLIQSM
                                     ::::::::::::::::::::::::::::::
NP_751                     MVLGTIDLCSCFSAGLPKTEANWVNVISDLKKIEDLIQSM
                                   10        20        30        40

        70        80        90       100       110       120       
pF1KB6 HIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILANNSLSSNGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 HIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILANNSLSSNGN
               50        60        70        80        90       100

       130       140       150       160  
pF1KB6 VTESGCKECEELEEKNIKEFLQSFVHIVQMFINTS
       :::::::::::::::::::::::::::::::::::
NP_751 VTESGCKECEELEEKNIKEFLQSFVHIVQMFINTS
              110       120       130     

>>NP_068575 (OMIM: 605384,615767) interleukin-21 isoform  (162 aa)
 initn:  82 init1:  52 opt: 125  Z-score: 178.2  bits: 39.2 E(85289): 0.0035
Smith-Waterman score: 125; 25.9% identity (61.2% similar) in 116 aa overlap (51-160:43-149)

               30        40        50         60        70         
pF1KB6 LNSHFLTEAGIHVFILGCFSAGLPKTEANWVNVISDLKK-IEDLIQSMHIDATLYTESDV
                                     ......::. ..::.  .     : .  ::
NP_068 ICLMVIFLGTLVHKSSSQGQDRHMIRMRQLIDIVDQLKNYVNDLVPEF-----LPAPEDV
             20        30        40        50        60            

      80        90       100       110         120       130       
pF1KB6 HPSCKVTAMKCFLLELQVISLESGDASIHDTVENLII--LANNSLSSNGNVTESG---CK
       . .:. .:..::    :  .:.:.... .. . :. :  :  .  :.:..  ..    : 
NP_068 ETNCEWSAFSCF----QKAQLKSANTGNNERIINVSIKKLKRKPPSTNAGRRQKHRLTCP
        70            80        90       100       110       120   

          140       150       160             
pF1KB6 ECEELEEKNIKEFLQSFVHIVQMFINTS           
        :.  :.:  ::::. :  ..: .:.             
NP_068 SCDSYEKKPPKEFLERFKSLLQKMIHQHLSSRTHGSEDS
           130       140       150       160  

>>NP_001193935 (OMIM: 605384,615767) interleukin-21 isof  (153 aa)
 initn:  78 init1:  52 opt: 121  Z-score: 173.1  bits: 38.2 E(85289): 0.0067
Smith-Waterman score: 121; 25.9% identity (60.7% similar) in 112 aa overlap (51-156:43-145)

               30        40        50         60        70         
pF1KB6 LNSHFLTEAGIHVFILGCFSAGLPKTEANWVNVISDLKK-IEDLIQSMHIDATLYTESDV
                                     ......::. ..::.  .     : .  ::
NP_001 ICLMVIFLGTLVHKSSSQGQDRHMIRMRQLIDIVDQLKNYVNDLVPEF-----LPAPEDV
             20        30        40        50        60            

      80        90       100       110         120       130       
pF1KB6 HPSCKVTAMKCFLLELQVISLESGDASIHDTVENLII--LANNSLSSNGNVTESG---CK
       . .:. .:..::    :  .:.:.... .. . :. :  :  .  :.:..  ..    : 
NP_001 ETNCEWSAFSCF----QKAQLKSANTGNNERIINVSIKKLKRKPPSTNAGRRQKHRLTCP
        70            80        90       100       110       120   

          140       150       160    
pF1KB6 ECEELEEKNIKEFLQSFVHIVQMFINTS  
        :.  :.:  ::::. :  ..:        
NP_001 SCDSYEKKPPKEFLERFKSLLQKVSTLSFI
           130       140       150   




162 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 04:01:31 2016 done: Sat Nov  5 04:01:32 2016
 Total Scan time:  4.950 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]