Result of FASTA (ccds) for
pFN21AE0628
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0628, 372 aa
1>>>pF1KE0628 372 - 372 aa - 372 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.5838+/-0.00142; mu= -0.5957+/- 0.081
mean_var=301.2767+/-71.579, 0's: 0 Z-trim(106.0): 629 B-trim: 96 in 1/49
Lambda= 0.073891
statistics sampled from 7973 (8757) to 7973 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.63), E-opt: 0.2 (0.269), width: 16
Scan time: 2.870
The best scores are: opt bits E(32554)
CCDS2315.1 STK17B gene_id:9262|Hs108|chr2 ( 372) 2459 276.6 2.5e-74
CCDS5470.1 STK17A gene_id:9263|Hs108|chr7 ( 414) 1230 145.6 7.3e-35
CCDS12116.1 DAPK3 gene_id:1613|Hs108|chr19 ( 454) 860 106.2 5.8e-23
CCDS43842.1 DAPK1 gene_id:1612|Hs108|chr9 (1430) 865 107.4 8.2e-23
CCDS10188.1 DAPK2 gene_id:23604|Hs108|chr15 ( 370) 832 103.1 4e-22
CCDS13191.1 MYLK2 gene_id:85366|Hs108|chr20 ( 596) 682 87.4 3.5e-17
CCDS34330.1 MYLK4 gene_id:340156|Hs108|chr6 ( 388) 678 86.8 3.6e-17
CCDS43141.1 MYLK gene_id:4638|Hs108|chr3 (1845) 667 86.4 2.2e-16
CCDS46896.1 MYLK gene_id:4638|Hs108|chr3 (1914) 667 86.4 2.2e-16
CCDS76861.1 MYLK3 gene_id:91807|Hs108|chr16 ( 478) 654 84.3 2.4e-16
CCDS10723.2 MYLK3 gene_id:91807|Hs108|chr16 ( 819) 654 84.6 3.4e-16
CCDS3028.1 KALRN gene_id:8997|Hs108|chr3 (1289) 637 83.0 1.6e-15
CCDS3883.1 TRIO gene_id:7204|Hs108|chr5 (3097) 613 80.9 1.6e-14
CCDS3704.1 CAMK2D gene_id:817|Hs108|chr4 ( 478) 578 76.2 6.7e-14
CCDS43263.1 CAMK2D gene_id:817|Hs108|chr4 ( 478) 578 76.2 6.7e-14
CCDS54797.1 CAMK2D gene_id:817|Hs108|chr4 ( 489) 578 76.2 6.8e-14
CCDS47127.1 CAMK2D gene_id:817|Hs108|chr4 ( 492) 578 76.2 6.8e-14
CCDS82950.1 CAMK2D gene_id:817|Hs108|chr4 ( 498) 578 76.2 6.8e-14
CCDS3703.1 CAMK2D gene_id:817|Hs108|chr4 ( 499) 578 76.2 6.8e-14
CCDS82948.1 CAMK2D gene_id:817|Hs108|chr4 ( 512) 578 76.2 7e-14
CCDS4103.1 CAMK4 gene_id:814|Hs108|chr5 ( 473) 577 76.1 7.1e-14
CCDS82949.1 CAMK2D gene_id:817|Hs108|chr4 ( 533) 578 76.3 7.1e-14
CCDS7336.1 CAMK2G gene_id:818|Hs108|chr10 ( 495) 577 76.1 7.3e-14
CCDS54421.1 TTN gene_id:7273|Hs108|chr2 (26926) 611 81.8 7.5e-14
CCDS54423.1 TTN gene_id:7273|Hs108|chr2 (27051) 611 81.8 7.5e-14
CCDS54422.1 TTN gene_id:7273|Hs108|chr2 (27118) 611 81.8 7.5e-14
CCDS7337.1 CAMK2G gene_id:818|Hs108|chr10 ( 527) 577 76.1 7.6e-14
CCDS73153.1 CAMK2G gene_id:818|Hs108|chr10 ( 539) 577 76.2 7.7e-14
CCDS7338.1 CAMK2G gene_id:818|Hs108|chr10 ( 556) 577 76.2 7.9e-14
CCDS54424.1 TTN gene_id:7273|Hs108|chr2 (33423) 611 82.0 8.6e-14
CCDS74610.1 TTN gene_id:7273|Hs108|chr2 (34350) 611 82.0 8.8e-14
CCDS59435.1 TTN gene_id:7273|Hs108|chr2 (35991) 611 82.0 9e-14
CCDS10851.1 PSKH1 gene_id:5681|Hs108|chr16 ( 424) 566 74.9 1.5e-13
CCDS43386.1 CAMK2A gene_id:815|Hs108|chr5 ( 478) 566 74.9 1.6e-13
CCDS43387.1 CAMK2A gene_id:815|Hs108|chr5 ( 489) 563 74.6 2e-13
CCDS42824.1 SPEG gene_id:10290|Hs108|chr2 (3267) 575 76.9 2.8e-13
CCDS7092.1 CAMK1D gene_id:57118|Hs108|chr10 ( 357) 553 73.4 3.5e-13
CCDS7091.1 CAMK1D gene_id:57118|Hs108|chr10 ( 385) 553 73.4 3.7e-13
CCDS58065.1 OBSCN gene_id:84033|Hs108|chr1 (7968) 571 76.9 6.7e-13
CCDS59204.1 OBSCN gene_id:84033|Hs108|chr1 (8923) 571 77.0 7.2e-13
CCDS2582.1 CAMK1 gene_id:8536|Hs108|chr3 ( 370) 528 70.7 2.3e-12
CCDS5489.1 CAMK2B gene_id:816|Hs108|chr7 ( 449) 528 70.8 2.6e-12
CCDS5488.1 CAMK2B gene_id:816|Hs108|chr7 ( 479) 528 70.9 2.7e-12
CCDS5487.1 CAMK2B gene_id:816|Hs108|chr7 ( 492) 528 70.9 2.7e-12
CCDS5486.1 CAMK2B gene_id:816|Hs108|chr7 ( 503) 528 70.9 2.8e-12
CCDS43573.1 CAMK2B gene_id:816|Hs108|chr7 ( 517) 528 70.9 2.8e-12
CCDS5485.1 CAMK2B gene_id:816|Hs108|chr7 ( 518) 528 70.9 2.8e-12
CCDS5484.1 CAMK2B gene_id:816|Hs108|chr7 ( 542) 528 70.9 2.9e-12
CCDS5483.1 CAMK2B gene_id:816|Hs108|chr7 ( 666) 528 71.0 3.3e-12
CCDS1486.1 CAMK1G gene_id:57172|Hs108|chr1 ( 476) 524 70.4 3.6e-12
>>CCDS2315.1 STK17B gene_id:9262|Hs108|chr2 (372 aa)
initn: 2459 init1: 2459 opt: 2459 Z-score: 1448.0 bits: 276.6 E(32554): 2.5e-74
Smith-Waterman score: 2459; 100.0% identity (100.0% similar) in 372 aa overlap (1-372:1-372)
10 20 30 40 50 60
pF1KE0 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 AKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 LCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 GMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 QETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 QETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFEN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRFRFDDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 LFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRFRFDDSL
310 320 330 340 350 360
370
pF1KE0 PNPHELVSDLLC
::::::::::::
CCDS23 PNPHELVSDLLC
370
>>CCDS5470.1 STK17A gene_id:9263|Hs108|chr7 (414 aa)
initn: 1259 init1: 1202 opt: 1230 Z-score: 739.4 bits: 145.6 E(32554): 7.3e-35
Smith-Waterman score: 1251; 54.5% identity (78.9% similar) in 374 aa overlap (13-367:41-413)
10 20 30 40
pF1KE0 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILT-SKELGR
:::: . .. : :.. : : ..::::
CCDS54 GSSPGATSGSGRAGRGLSGPCRPPPPPQARGLLTEIRAV-VRTEPFQDGYSLCPGRELGR
20 30 40 50 60
50 60 70 80 90 100
pF1KE0 GKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYE
:::::::.::.:..:.:.::::..:::.::::: ::.:::::::::.. : :::::::::
CCDS54 GKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWVINLHEVYE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 NTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKP
..::.::.::::::::::. :. . : .:.:: ::..::::::..:: ..:::::::
CCDS54 TASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKP
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 QNILLSSIYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNI
:::::.: :::::::::::.:: . .. :::::::::::.:::::.::::. :::::.:
CCDS54 QNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSI
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE0 GIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKR
:...:..:: :::.:.:.:::.:::::.:..:::: :. .:. :.:::..::::.:: :
CCDS54 GVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDR
250 260 270 280 290 300
290 300 310 320
pF1KE0 PTAEICLSHSWLQQWDF-ENLFHPEET--SSSSQTQDHSV---RSSEDKT-SKSS-----
::: ::.: :: : .. : :. :.. ... . ::: :. ::. .: :
CCDS54 ATAEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSETKESIVTEE
310 320 330 340 350 360
330 340 350 360 370
pF1KE0 ----CNGTCGDREDKENIPEDSSMVSKRFRFDDSLPN--PHELVSDLLC
. : :. ...:. ... .::::.:.. : . : :..
CCDS54 LIVVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQEIPGEFIY
370 380 390 400 410
>>CCDS12116.1 DAPK3 gene_id:1613|Hs108|chr19 (454 aa)
initn: 829 init1: 461 opt: 860 Z-score: 525.8 bits: 106.2 E(32554): 5.8e-23
Smith-Waterman score: 860; 41.6% identity (73.9% similar) in 341 aa overlap (24-355:5-340)
10 20 30 40 50 60
pF1KE0 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA
..:. .. : . ..::: :.::.::.: .:.::.:::
CCDS12 MSTFRQEDVEDHYEM-GEELGSGQFAIVRKCRQKGTGKEYA
10 20 30 40
70 80 90 100 110
pF1KE0 AKFLKKRR-----RGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAG
:::.:::: :: . : :: .:. .:. . : .:.::...:: ....:::: ..:
CCDS12 AKFIKKRRLSSSRRGVS-REEIEREVNILREIRH-PNIITLHDIFENKTDVVLILELVSG
50 60 70 80 90
120 130 140 150 160 170
pF1KE0 GEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNI-LLSSIYPLGD
::.:.. : : : ..:... ...::::.::.:::.. :.:.::::.:: ::.. :
CCDS12 GELFDF-LAE-KESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPR
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE0 IKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSP
::..:::...:: . :...:.::::..::::.::.:. .:::.::.:.:.::. .::
CCDS12 IKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASP
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE0 FVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQ
:.:: .::: ::: :: :..:: ::..:.:: :::. ::::.:..: : : :::..
CCDS12 FLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIK
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE0 QWDFENLFHPEETSSSSQTQDHSVRSSEDKTSKSSC---NGTCGDREDKENIPEDSSMVS
.:. . . . . ...: .: .. : :.. .: : .. :... .
CCDS12 AIRRRNVRGEDSGRKPERRRLKTTRLKEYTIKSHSSLPPNNSYADFERFSKVLEEAAAAE
280 290 300 310 320 330
360 370
pF1KE0 KRFRFDDSLPNPHELVSDLLC
. .:
CCDS12 EGLRELQRSRRLCHEDVEALAAIYEEKEAWYREESDSLGQDLRRLRQELLKTEALKRQAQ
340 350 360 370 380 390
>>CCDS43842.1 DAPK1 gene_id:1612|Hs108|chr9 (1430 aa)
initn: 789 init1: 420 opt: 865 Z-score: 523.0 bits: 107.4 E(32554): 8.2e-23
Smith-Waterman score: 873; 42.5% identity (72.4% similar) in 369 aa overlap (24-370:5-367)
10 20 30 40 50 60
pF1KE0 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA
..:: ...: :..::: :.::::..: :::: .::
CCDS43 MTVFRQENVDDYYD-TGEELGSGQFAVVKKCREKSTGLQYA
10 20 30 40
70 80 90 100 110
pF1KE0 AKFLKKRR-----RGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAG
:::.:::: :: . : .: .:...:. . : ::.::::::: ...::::: .::
CCDS43 AKFIKKRRTKSSRRGVS-REDIEREVSILKEIQH-PNVITLHEVYENKTDVILILELVAG
50 60 70 80 90
120 130 140 150 160 170
pF1KE0 GEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNI-LLSSIYPLGD
::.:.. : : : ..:... ...::::.::::::. .:.:.::::.:: ::. :
CCDS43 GELFDF-LAE-KESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPR
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE0 IKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSP
:::.:::...:: . :...:.::::..::::.::.:. .:::.::.:.:.::. .::
CCDS43 IKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASP
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE0 FVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQ
:.:. .::: :.: :: .. .: ::..: :: :::. ::::.:.:: : . :.: :..
CCDS43 FLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK
220 230 240 250 260 270
300 310 320 330 340
pF1KE0 QWDFENLFHPEETS---------SSSQTQDHSVR--SSEDKTSKS--SCNGTCGDREDKE
: .. . . .. .. . .::: : .. :.: : .. : : .
CCDS43 PKDTQQALSRKASAVNMEKFKKFAARKKWKQSVRLISLCQRLSRSFLSRSNMSVARSD-D
280 290 300 310 320 330
350 360 370
pF1KE0 NIPEDSSMVSKRFRF---DDSLPNPHELVSDLLC
.. :..:.: : . ::..:. ..:...:
CCDS43 TLDEEDSFVMKAIIHAINDDNVPGLQHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQIL
340 350 360 370 380 390
CCDS43 QLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARY
400 410 420 430 440 450
>>CCDS10188.1 DAPK2 gene_id:23604|Hs108|chr15 (370 aa)
initn: 795 init1: 409 opt: 832 Z-score: 510.7 bits: 103.1 E(32554): 4e-22
Smith-Waterman score: 832; 46.7% identity (77.7% similar) in 287 aa overlap (18-297:8-289)
10 20 30 40 50
pF1KE0 MSRRRFDCRSISGLLTTTPQI-PIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEY
.:.. :.:... ..:: . ..::: :.::.:..: :::: ::
CCDS10 MFQASMRSPNMEPFKQQKVEDFYDI-GEELGSGQFAIVKKCREKSTGLEY
10 20 30 40
60 70 80 90 100 110
pF1KE0 AAKFLKKR-----RRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAA
::::.::: ::: . : :: .:...:. . ::.::.:::: ....:::: ..
CCDS10 AAKFIKKRQSRASRRGVS-REEIEREVSILRQVLH-HNVITLHDVYENRTDVVLILELVS
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE0 GGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNI-LLSSIYPLG
:::.:.. . : .::... .:::::.:: ::: ..:.:.::::.:: ::.. :.
CCDS10 GGELFDFLAQK--ESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIP
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE0 DIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTS
::..:::....: . :...:.::::..::::.::.:. .:::.::.:.:.::. .:
CCDS10 HIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGAS
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE0 PFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWL
::.:. .::: ::. :. :..:: ::..:.:: :::..::::. .:: : . : : :.
CCDS10 PFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWI
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE0 QQWDFENLFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKR
:
CCDS10 TPVDNQQAMVRRESVVNLENFRKQYVRRRWKLSFSIVSLCNHLTRSLMKKVHLRPDEDLR
290 300 310 320 330 340
>>CCDS13191.1 MYLK2 gene_id:85366|Hs108|chr20 (596 aa)
initn: 659 init1: 405 opt: 682 Z-score: 421.9 bits: 87.4 E(32554): 3.5e-17
Smith-Waterman score: 682; 37.9% identity (67.4% similar) in 301 aa overlap (1-293:246-540)
10 20
pF1KE0 MSRRRFDCRSISGLLTTTP------QIPIK
.. :. :: .: : .. ..
CCDS13 GQAKMQGDTSRGIEFQAVPSEKSEVGQALCLTAREEDCFQILDDCPPPPAPFPHRMVELR
220 230 240 250 260 270
30 40 50 60 70 80
pF1KE0 MENFNNFYILTSKE-LGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAV
: .. . ..::: :: :::..: :. :.:: . ::: .::. .: . .: :: :
CCDS13 TGNVSSEFSMNSKEALGGGKFGAVCTCMEKATGLKLAAKVIKKQT-PKD-KEMVLLEIEV
280 290 300 310 320 330
90 100 110 120 130 140
pF1KE0 LELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQIL
.. . .:.:. . :. ::.:..:: :::.: . : .. .: :.. ...::
CCDS13 MNQLNH-RNLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHL-TEVDTMVFVRQIC
340 350 360 370 380 390
150 160 170 180 190 200
pF1KE0 EGVYYLHQNNIVHLDLKPQNILLSSIYPLGD-IKIVDFGMSRKIGHACELREIMGTPEYL
.:. ..:. ..::::::.::: . : .::.:::..:. . .:. .::::.:
CCDS13 DGILFMHKMRVLHLDLKPENIL--CVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFL
400 410 420 430 440
210 220 230 240 250 260
pF1KE0 APEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSV
.::..::: :. ::::..:.:.::::. :::.:.:. :: :. . : ..:::: .:
CCDS13 SPEVVNYDQISDKTDMWSMGVITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAV
450 460 470 480 490 500
270 280 290 300 310 320
pF1KE0 SQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFENLFHPEETSSSSQTQDHSVRSSE
:. : ::...:.::. . : .: ::.: ::
CCDS13 SDEAKDFVSNLIVKDQRARMNAAQCLAHPWLNNLAEKAKRCNRRLKSQILLKKYLMKRRW
510 520 530 540 550 560
330 340 350 360 370
pF1KE0 DKTSKSSCNGTCGDREDKENIPEDSSMVSKRFRFDDSLPNPHELVSDLLC
CCDS13 KKNFIAVSAANRFKKISSSGALMALGV
570 580 590
>>CCDS34330.1 MYLK4 gene_id:340156|Hs108|chr6 (388 aa)
initn: 593 init1: 371 opt: 678 Z-score: 421.7 bits: 86.8 E(32554): 3.6e-17
Smith-Waterman score: 678; 37.7% identity (70.0% similar) in 297 aa overlap (21-315:93-384)
10 20 30 40
pF1KE0 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKE-LGRGKFAVVRQ
. :. :.:: ... : :: :.:. :..
CCDS34 LTERMPVKSKRTSALAVDIPAPPAPFDHRIVTAKQGAVNSFYTVSKTEILGGGRFGQVHK
70 80 90 100 110 120
50 60 70 80 90 100
pF1KE0 CISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILI
: .:: . :::..: : :. . :. .::.:.. .:.:....:. ..:.:.
CCDS34 CEETATGLKLAAKIIKTR--GMKDKEEVKNEISVMNQLDHA-NLIQLYDAFESKNDIVLV
130 140 150 160 170
110 120 130 140 150 160
pF1KE0 LEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSI
.::. :::.:. . : . ..: :.: ..::: ::. ..:: :.::::::.::: .
CCDS34 MEYVDGGELFDRIIDE-SYNLTELDTILFMKQICEGIRHMHQMYILHLDLKPENILCVN-
180 190 200 210 220 230
170 180 190 200 210 220
pF1KE0 YPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLL
.:::.:::..:. .:. .::::.::::..::: .. ::::..:.::::::
CCDS34 RDAKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYDFVSFPTDMWSVGVIAYMLL
240 250 260 270 280 290
230 240 250 260 270 280
pF1KE0 THTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLS
. :::.:... :: :: : .: :...:. : .::..::.:. : .: :.
CCDS34 SGLSPFLGDNDAETLNNILACRWDLEDEEFQDISEEAKEFISKLLIKEKSWRISASEALK
300 310 320 330 340 350
290 300 310 320 330 340
pF1KE0 HSWLQQWDFENLFHPEETSS-SSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSS
: ::.. ... .. .. .. .:..::
CCDS34 HPWLSDHKLHSRLNAQKKKNRGSDAQDFVTK
360 370 380
>>CCDS43141.1 MYLK gene_id:4638|Hs108|chr3 (1845 aa)
initn: 584 init1: 402 opt: 667 Z-score: 407.7 bits: 86.4 E(32554): 2.2e-16
Smith-Waterman score: 667; 35.2% identity (72.0% similar) in 304 aa overlap (26-328:1389-1682)
10 20 30 40 50
pF1KE0 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKST
.. ..:: . . :: :::. : . . :.:
CCDS43 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEER-LGSGKFGQVFRLVEKKT
1360 1370 1380 1390 1400 1410
60 70 80 90 100 110
pF1KE0 GQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAG
. .:.::.: . . .: .::.... . :.... ...:. ..:...:: ..:
CCDS43 RKVWAGKFFKAYSAKE--KENIRQEISIMNCLHH-PKLVQCVDAFEEKANIVMVLEIVSG
1420 1430 1440 1450 1460 1470
120 130 140 150 160 170
pF1KE0 GEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGD-
::.: . : :. .: . :. ..:: ::: :.:...::::::::.::. . :
CCDS43 GELFERIIDEDFEL-TERECIKYMRQISEGVEYIHKQGIVHLDLKPENIM--CVNKTGTR
1480 1490 1500 1510 1520 1530
180 190 200 210 220 230
pF1KE0 IKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSP
::..:::..:.. .: :. ..::::..:::..::.:: :::::.::.: :.:.. ::
CCDS43 IKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSP
1540 1550 1560 1570 1580 1590
240 250 260 270 280 290
pF1KE0 FVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQ
:.:....:: :..... :...:.:. .:. : :::..:: :. ..: ::.: ::.
CCDS43 FMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLM
1600 1610 1620 1630 1640 1650
300 310 320 330 340 350
pF1KE0 QWDFENLFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRF
. : .:. . :... . . .: . .::...
CCDS43 K-DTKNM--EAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSP
1660 1670 1680 1690 1700
360 370
pF1KE0 RFDDSLPNPHELVSDLLC
CCDS43 TSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPD
1710 1720 1730 1740 1750 1760
>>CCDS46896.1 MYLK gene_id:4638|Hs108|chr3 (1914 aa)
initn: 584 init1: 402 opt: 667 Z-score: 407.5 bits: 86.4 E(32554): 2.2e-16
Smith-Waterman score: 667; 35.2% identity (72.0% similar) in 304 aa overlap (26-328:1458-1751)
10 20 30 40 50
pF1KE0 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKST
.. ..:: . . :: :::. : . . :.:
CCDS46 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEER-LGSGKFGQVFRLVEKKT
1430 1440 1450 1460 1470 1480
60 70 80 90 100 110
pF1KE0 GQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAG
. .:.::.: . . .: .::.... . :.... ...:. ..:...:: ..:
CCDS46 RKVWAGKFFKAYSAKE--KENIRQEISIMNCLHH-PKLVQCVDAFEEKANIVMVLEIVSG
1490 1500 1510 1520 1530 1540
120 130 140 150 160 170
pF1KE0 GEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGD-
::.: . : :. .: . :. ..:: ::: :.:...::::::::.::. . :
CCDS46 GELFERIIDEDFEL-TERECIKYMRQISEGVEYIHKQGIVHLDLKPENIM--CVNKTGTR
1550 1560 1570 1580 1590 1600
180 190 200 210 220 230
pF1KE0 IKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSP
::..:::..:.. .: :. ..::::..:::..::.:: :::::.::.: :.:.. ::
CCDS46 IKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSP
1610 1620 1630 1640 1650 1660
240 250 260 270 280 290
pF1KE0 FVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQ
:.:....:: :..... :...:.:. .:. : :::..:: :. ..: ::.: ::.
CCDS46 FMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLM
1670 1680 1690 1700 1710 1720
300 310 320 330 340 350
pF1KE0 QWDFENLFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRF
. : .:. . :... . . .: . .::...
CCDS46 K-DTKNM--EAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSP
1730 1740 1750 1760 1770
360 370
pF1KE0 RFDDSLPNPHELVSDLLC
CCDS46 TSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPD
1780 1790 1800 1810 1820 1830
>>CCDS76861.1 MYLK3 gene_id:91807|Hs108|chr16 (478 aa)
initn: 616 init1: 376 opt: 654 Z-score: 406.9 bits: 84.3 E(32554): 2.4e-16
Smith-Waterman score: 654; 40.0% identity (69.5% similar) in 275 aa overlap (21-293:161-429)
10 20 30 40
pF1KE0 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKE-LGRGKFAVVRQ
. .: ... : . ..: :: :.:. :..
CCDS76 AVRRMPPGAEAGSVVLDDSPAPPAPFEHRVVSVKETSISAGYEVCQHEVLGGGRFGQVHR
140 150 160 170 180 190
50 60 70 80 90 100
pF1KE0 CISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILI
: :::: :::..: . ..: : .. .:: ... : .:.:....:. :.
CCDS76 CTEKSTGLPLAAKIIKVKS-AKD-REDVKNEINIMN-QLSHVNLIQLYDAFESKHSCTLV
200 210 220 230 240
110 120 130 140 150 160
pF1KE0 LEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSI
.::. :::.:. : .. .: ::. . .:: :::.::::. :.::::::.::: .
CCDS76 MEYVDGGELFDRITDEKYHL-TELDVVLFTRQICEGVHYLHQHYILHLDLKPENIL--CV
250 260 270 280 290 300
170 180 190 200 210 220
pF1KE0 YPLG-DIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYML
: .:::.:::..:. .:. .::::.::::..::. .. ::::..:.:.:::
CCDS76 NQTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYML
310 320 330 340 350 360
230 240 250 260 270 280
pF1KE0 LTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICL
:. :::.:: . ::. : . . :.. .:: ..:. : ::.. ::::. : .: ::
CCDS76 LSGLSPFLGETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCL
370 380 390 400 410 420
290 300 310 320 330 340
pF1KE0 SHSWLQQWDFENLFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSS
.: ::
CCDS76 KHEWLNNLPAKASRSKTRLKSQLLLQKYIAQRKWKKHFYVVTAANRLRKFPTSP
430 440 450 460 470
372 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:23:45 2016 done: Tue Nov 8 01:23:46 2016
Total Scan time: 2.870 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]